Effects of light-to-moderate alcohol consumption on steatosis and steatohepatitis in severely obese patients

European Journal of Gastroenterology and Hepatology

Volumn 21, Issue 9, 2009, Pages 969-972

  Cotrim, Helma P ^a,e   Freitas, Luiz Antônio ^b   Alves, Erivaldo ^c   Almeida, Alessandro ^a   May, Daniel S ^a   Caldwell, Stephen ^d  

^a FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c Center for the Surgical Treatment of Obesity   (Brazil)

^d UNIVERSITY OF VIRGINIA   (United States)

^e Programa de Pós Graduação Em Medicina e Saúde PPGMS   (Brazil)

Author keywords

Alcoholic liver disease; Insulin resistance; Nonalcoholic fatty liver disease; Obesity

Indexed keywords

ALCOHOL;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BARIATRIC SURGERY; BODY MASS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATION; INSULIN RESISTANCE; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER DISEASE; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; OBESITY; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STEATOSIS;

ADULT; AGED; ALCOHOL DRINKING; BARIATRIC SURGERY; BODY MASS INDEX; CROSS-SECTIONAL STUDIES; FATTY LIVER; FEMALE; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED; OBESITY, MORBID; YOUNG ADULT;

EID: 69549122913     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MEG.0b013e328328f3ec     Document Type: Article

References (26)

1. Mokdad AH, Serdula MK, Dietz WH, Bowman BA, Marks JS, Koplan JP. The spread of the obesity epidemic in the United States, 1991-1998. JAMA 1999; 282:1519-1522.
2. World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser 2000; 894:i-xii, 1-253.
3. Australian Institute of Health and Welfare. Australia's Health 1998: the Sixth Biennial Health Report of the Australian Institute of Health and Welfare, 1998: 150-151 Australian Institute of Health and Welfare Canberra, Australia.
4. Flegal KM, Carroll MD, Kuczmarski RJ, Johnson CL. Overweight and obesity in the United States: prevalence and trends, 1960-1994. Int J Obes Relat Metab Disord 1998; 22:39-47.
5. Timar O, Sestier F, Levy E. Metabolic syndrome X: a review. Can J Cardiol 2000; 16:779-789.
6. Bell RA, Mayer-Davis EJ, Martin MA, D'Agostino RB Jr, Haffner SM. Associations between alcohol consumption and insulin sensitivity and cardiovascular disease risk factors: the insulin resistance and atherosclerosis study. Diabetes Care 2000; 23:1630-1636.
7. Keil U, Chambless LE, Doring A, Filipiak B, Stieber J. The relation of alcohol intake to coronary heart disease and all-cause mortality in a beer-drinking population. Epidemiology 1997; 8:150-156. (Pubitemid 27084185)
8. Bitencourt AG, Cotrim HP, Alves E, Almeida AM, Barbosa DBV, Santos AS D, et al. Doença hepática gordurosa não alcoólica: características clínicas e histológicas em obesos graves submetidos à cirurgia bariátrica (Nonalcoholic fatty liver disease: clinical and histological characteristics in obese who underwent bariatric surgery). Acta Gastroenterol Latinoam 2007; 37:224-230.
9. Guidorizzi de Siqueira AC, Cotrim HP, Rocha R, Carvalho FM, Freitas LAR, Barreto D, et al. Non-alcoholic fatty liver disease and insulin resistance: importance of risk factors and histological spectrum. Eur J Gastroenterol Hepatol 2005; 17:837-841. (Pubitemid 41073321)
10. Matteoni CA, Younossi ZM, Gramlich T, Boparai N, Liu YC, McCullough AJ. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999; 126:1413-1419. (Pubitemid 29258890)
11. Brunt EM, Neuschwander-Tetri BA, Oliver D, Wehmeier KR, Bacon BR. Nonalcoholic steatohepatitis: histologic features and clinical correlations with 30 blinded biopsy specimens. Hum Pathol 2004; 35:1070-1082. (Pubitemid 39165338)
12. Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41:1313-1321. (Pubitemid 40770284)
13. Dixon JB, Dixon ME, O'Brien PE. Alcohol consumption in the severely obese: relationship with the metabolic syndrome. Obes Res 2002; 10:245-252. (Pubitemid 135688231)
14. Junqueira LCU, Bignoles G, Brentani RR. Picrosirius staining plus polarization microcopy, a specific method for collagen detection in tissue sections. Histochem J 1979; 11:447-455.
15. Lidfeldt J, Nyberg P, Nerbrand C, Samsioe G, Schersten B, Agardh CD. Socio-demographic and psychosocial factors are associated with features ofthe metabolic syndrome: the Women's Health in the Lund Area (WHILA) Study. Diabetes Obes Metab 2003; 5:106-112. (Pubitemid 36372502)
16. Rosell M, de Faire U, Hellenius ML. Low prevalence of the metabolic syndrome in wine drinkers: is it the alcohol beverage or the lifestyle? Eur J Clin Nutr 2003; 57:227-234.
17. Solymoss BC, Bourassa MG, Lesperance J, Levesque S, Marcil M, Varga S, Campeau L. Incidence and clinical characteristics of the metabolic syndrome in patients with coronary artery disease. Coron Artery Dis 2003; 14:207-212. (Pubitemid 36578047)
18. Hulley SB, Gordon S. Alcohol and high-density lipoprotein cholesterol: causal inference from diverse study designs. Circulation 1981; 64:57-63. (Pubitemid 12224305)
19. Kiechl S, Willeit J, Poewe W, Egger G, Oberhollenzer F, Muggeo M, Bonora E. Insulin sensitivity and regular alcohol consumption: large, prospective, cross sectional population study (Bruneck study). BMJ 1996; 313:1040-1044. (Pubitemid 26371868)
20. Meyer KA, Conigrave KM, Chu NF, Rifai N, Spiegelman D, Stampfer MJ, Rimm EB. Alcohol consumption patterns and HbA1c, C-peptide and insulin concentrations in men. J Am Coll Nutr 2003; 22:185-194. (Pubitemid 36706265)
21. Shelmet JJ, Reichard GA, Skutches CL, Hoeldtke RD, Owen OE, Boden G. Ethanol causes acute inhibition of carbohydrates, fat, and protein oxidation and insulin resistance. J Clin Invest 1988; 81:1137-1145. (Pubitemid 18129405)
22. Lazarus S, Sparrow D, Weiss S. Alcohol intake and insulin levels. The Normative Aging Study. Am J Epidemiol 1997; 145:909-916. (Pubitemid 27200777)
23. Kiechl S,Willeit J, Poewe W, Egger G, Oberhollenzer F, Muggeo M, Bonora E. Insulin sensitivity and regular alcohol consumption: large, prospective, cross-sectional population study. BMJ 1996; 313:1040-1044. (Pubitemid 26371868)
24. Singh SP, Kumar Y, Snyder AK, Ellyin FE, Gilden JL. Effect of alcohol on glucose tolerance in normal and noninsulin-dependent diabetic subjects. Alcohol Clin Exp Res 1988; 12:727-730. (Pubitemid 19018871)
25. Dixon JB, Dixon ME, O'Brien PE. Pre-operative predictors of weight loss at 1-year after lap-band surgery. Obes Surg 2001; 11:200-207.
26. Dunn W, Xu R, Schwimmer JB. Modest wine drinking and decreased prevalence of suspected nonalcoholic fatty liver disease. Hepatology 2008; 47:1947-1954. (Pubitemid 351945562)