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Volumn 121, Issue 1, 2015, Pages 41-52

EGCG inhibits properties of glioma stem-like cells and synergizes with temozolomide through downregulation of P-glycoprotein inhibition

Author keywords

EGCG; Glioma; Neurosphere culture; P gp; Stem cell; Temozolomide

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 1; ANTINEOPLASTIC AGENT; CATECHIN; DACARBAZINE; EPIGALLOCATECHIN GALLATE; ISOENZYME; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; RETINAL DEHYDROGENASE; TEMOZOLOMIDE;

EID: 84921055072     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-014-1604-1     Document Type: Article
Times cited : (94)

References (50)
  • 1
    • 49649104978 scopus 로고    scopus 로고
    • Mechanisms of chemoresistance to alkylating agents in malignant glioma
    • COI: 1:CAS:528:DC%2BD1cXmtVCmt7s%3D, PID: 18483356
    • Sarkaria JN, Kitange GJ, James CD, Plummer R, Calvert H, Weller M, Wick W (2008) Mechanisms of chemoresistance to alkylating agents in malignant glioma. Clin Cancer Res 14:2900–2908. doi:10.1158/1078-0432.CCR-07-1719
    • (2008) Clin Cancer Res , vol.14 , pp. 2900-2908
    • Sarkaria, J.N.1    Kitange, G.J.2    James, C.D.3    Plummer, R.4    Calvert, H.5    Weller, M.6    Wick, W.7
  • 2
    • 84875718417 scopus 로고    scopus 로고
    • Chemotherapy for gliomas in mainland China: an overview
    • COI: 1:CAS:528:DC%2BC3sXnvFygtr0%3D, PID: 23761809
    • Sai K, Yang QY, Shen D, Chen ZP (2013) Chemotherapy for gliomas in mainland China: an overview. Oncol Lett 5:1448–1452. doi:10.3892/ol.2013.1264
    • (2013) Oncol Lett , vol.5 , pp. 1448-1452
    • Sai, K.1    Yang, Q.Y.2    Shen, D.3    Chen, Z.P.4
  • 3
    • 4944250781 scopus 로고    scopus 로고
    • Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
    • COI: 1:CAS:528:DC%2BD2cXotFalsLs%3D, PID: 15466194
    • Galli R, Binda E, Orfanelli U, Cipelletti B, Gritti A, De Vitis S, Fiocco R, Foroni C, Dimeco F, Vescovi A (2004) Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 64:7011–7021. doi:10.1158/0008-5472.CAN-04-1364
    • (2004) Cancer Res , vol.64 , pp. 7011-7021
    • Galli, R.1    Binda, E.2    Orfanelli, U.3    Cipelletti, B.4    Gritti, A.5    De Vitis, S.6    Fiocco, R.7    Foroni, C.8    Dimeco, F.9    Vescovi, A.10
  • 4
    • 79960656490 scopus 로고    scopus 로고
    • O(6)-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry
    • COI: 1:CAS:528:DC%2BC3MXhsVKmtrjO, PID: 21745538
    • Christmann M, Verbeek B, Roos WP, Kaina B (2011) O(6)-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry. Biochim Biophys Acta 1816:179–190. doi:10.1016/j.bbcan.2011.06.002
    • (2011) Biochim Biophys Acta , vol.1816 , pp. 179-190
    • Christmann, M.1    Verbeek, B.2    Roos, W.P.3    Kaina, B.4
  • 5
    • 70350150304 scopus 로고    scopus 로고
    • Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma
    • COI: 1:CAS:528:DC%2BD1MXhsVyisrjP, PID: 19832037
    • Nakai E, Park K, Yawata T, Chihara T, Kumazawa A, Nakabayashi H, Shimizu K (2009) Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma. Cancer Invest 27:901–908. doi:10.3109/07357900801946679
    • (2009) Cancer Invest , vol.27 , pp. 901-908
    • Nakai, E.1    Park, K.2    Yawata, T.3    Chihara, T.4    Kumazawa, A.5    Nakabayashi, H.6    Shimizu, K.7
  • 6
    • 79954504838 scopus 로고    scopus 로고
    • Preliminary screening and identification of stem cell-like sphere clones in a gallbladder cancer cell line GBC-SD
    • PID: 21462380
    • Yin BB, Wu SJ, Zong HJ, Ma BJ, Cai D (2011) Preliminary screening and identification of stem cell-like sphere clones in a gallbladder cancer cell line GBC-SD. J Zhejiang Univ Sci B 12:256–263. doi:10.1631/jzus.B1000303
    • (2011) J Zhejiang Univ Sci B , vol.12 , pp. 256-263
    • Yin, B.B.1    Wu, S.J.2    Zong, H.J.3    Ma, B.J.4    Cai, D.5
  • 7
    • 3042569646 scopus 로고    scopus 로고
    • Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance
    • COI: 1:CAS:528:DC%2BD2cXkvFWltr4%3D, PID: 15205350
    • Imai Y, Tsukahara S, Asada S, Sugimoto Y (2004) Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance. Cancer Res 64:4346–4352. doi:10.1158/0008-5472.CAN-04-0078
    • (2004) Cancer Res , vol.64 , pp. 4346-4352
    • Imai, Y.1    Tsukahara, S.2    Asada, S.3    Sugimoto, Y.4
  • 8
    • 32544451627 scopus 로고    scopus 로고
    • Reversal of MDR1/P-glycoprotein-mediated multidrug resistance by vector-based RNA interference in vitro and in vivo
    • COI: 1:CAS:528:DC%2BD28XkvVSntrk%3D, PID: 16319528
    • Shi Z, Liang YJ, Chen ZS, Wang XW, Wang XH, Ding Y, Chen LM, Yang XP, Fu LW (2006) Reversal of MDR1/P-glycoprotein-mediated multidrug resistance by vector-based RNA interference in vitro and in vivo. Cancer Biol Ther 5:39–47
    • (2006) Cancer Biol Ther , vol.5 , pp. 39-47
    • Shi, Z.1    Liang, Y.J.2    Chen, Z.S.3    Wang, X.W.4    Wang, X.H.5    Ding, Y.6    Chen, L.M.7    Yang, X.P.8    Fu, L.W.9
  • 9
    • 84884813627 scopus 로고    scopus 로고
    • Bortezomib overcomes MGMT-related resistance of glioblastoma cell lines to temozolomide in a schedule-dependent manner
    • PID: 23645448
    • Vlachostergios PJ, Hatzidaki E, Befani CD, Liakos P, Papandreou CN (2013) Bortezomib overcomes MGMT-related resistance of glioblastoma cell lines to temozolomide in a schedule-dependent manner. Invest New Drugs. doi:10.1007/s10637-013-9968-1
    • (2013) Invest New Drugs
    • Vlachostergios, P.J.1    Hatzidaki, E.2    Befani, C.D.3    Liakos, P.4    Papandreou, C.N.5
  • 10
    • 80555123045 scopus 로고    scopus 로고
    • Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications
    • COI: 1:CAS:528:DC%2BC3MXhsVaqsb3K, PID: 21827739
    • Singh BN, Shankar S, Srivastava RK (2011) Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochem Pharmacol 82:1807–1821. doi:10.1016/j.bcp.2011.07.093
    • (2011) Biochem Pharmacol , vol.82 , pp. 1807-1821
    • Singh, B.N.1    Shankar, S.2    Srivastava, R.K.3
  • 11
    • 34547680062 scopus 로고    scopus 로고
    • Green tea polyphenols: biology and therapeutic implications in cancer
    • COI: 1:CAS:528:DC%2BD2sXosF2ru7g%3D, PID: 17569617
    • Shankar S, Ganapathy S, Srivastava RK (2007) Green tea polyphenols: biology and therapeutic implications in cancer. Front Biosci 12:4881–4899
    • (2007) Front Biosci , vol.12 , pp. 4881-4899
    • Shankar, S.1    Ganapathy, S.2    Srivastava, R.K.3
  • 12
    • 84873992343 scopus 로고    scopus 로고
    • Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation
    • COI: 1:CAS:528:DC%2BC3sXhvFSls7k%3D, PID: 23333498
    • Chen H, Landen CN, Li Y, Alvarez RD, Tollefsbol TO (2013) Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation. Exp Cell Res 319:697–706. doi:10.1016/j.yexcr.2012.12.026
    • (2013) Exp Cell Res , vol.319 , pp. 697-706
    • Chen, H.1    Landen, C.N.2    Li, Y.3    Alvarez, R.D.4    Tollefsbol, T.O.5
  • 13
    • 34347251957 scopus 로고    scopus 로고
    • The green tea polyphenol, epigallocatechin-3-gallate inhibits telomerase and induces apoptosis in drug-resistant lung cancer cells
    • COI: 1:CAS:528:DC%2BD2sXntFamt70%3D, PID: 17585882
    • Sadava D, Whitlock E, Kane SE (2007) The green tea polyphenol, epigallocatechin-3-gallate inhibits telomerase and induces apoptosis in drug-resistant lung cancer cells. Biochem Biophys Res Commun 360:233–237. doi:10.1016/j.bbrc.2007.06.030
    • (2007) Biochem Biophys Res Commun , vol.360 , pp. 233-237
    • Sadava, D.1    Whitlock, E.2    Kane, S.E.3
  • 14
    • 76749101143 scopus 로고    scopus 로고
    • (-)-Epigallocatechin-3-gallate downregulates Pg-P and BCRP in a tamoxifen resistant MCF-7 cell line
    • COI: 1:CAS:528:DC%2BC3cXlvFOmt74%3D, PID: 20149610
    • Farabegoli F, Papi A, Bartolini G, Ostan R, Orlandi M (2010) (-)-Epigallocatechin-3-gallate downregulates Pg-P and BCRP in a tamoxifen resistant MCF-7 cell line. Phytomedicine 17:356–362. doi:10.1016/j.phymed.2010.01.001
    • (2010) Phytomedicine , vol.17 , pp. 356-362
    • Farabegoli, F.1    Papi, A.2    Bartolini, G.3    Ostan, R.4    Orlandi, M.5
  • 15
    • 80052446519 scopus 로고    scopus 로고
    • Reversal effect of 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone on multi-drug resistance in resistant human hepatocellular carcinoma cell line BEL-7402/5-FU
    • COI: 1:CAS:528:DC%2BC3MXhtFait7rF, PID: 21596545
    • Huang HY, Niu JL, Zhao LM, Lu YH (2011) Reversal effect of 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone on multi-drug resistance in resistant human hepatocellular carcinoma cell line BEL-7402/5-FU. Phytomedicine 18:1086–1092. doi:10.1016/j.phymed.2011.04.001
    • (2011) Phytomedicine , vol.18 , pp. 1086-1092
    • Huang, H.Y.1    Niu, J.L.2    Zhao, L.M.3    Lu, Y.H.4
  • 16
    • 0019551730 scopus 로고
    • Western blotting”: electrophoretic transfer of proteins from sodium dodecyl sulfate–polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
    • COI: 1:CAS:528:DyaL3MXhvVOqtbs%3D, PID: 6266278
    • Burnette WN (1981) “Western blotting”: electrophoretic transfer of proteins from sodium dodecyl sulfate–polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem 112:195–203
    • (1981) Anal Biochem , vol.112 , pp. 195-203
    • Burnette, W.N.1
  • 17
    • 77955158299 scopus 로고    scopus 로고
    • The utility and limitations of neurosphere assay, CD133 immunophenotyping and side population assay in glioma stem cell research
    • COI: 1:CAS:528:DC%2BC3cXhtFKht7bN, PID: 20331619
    • Wan F, Zhang S, Xie R, Gao B, Campos B, Herold-Mende C, Lei T (2010) The utility and limitations of neurosphere assay, CD133 immunophenotyping and side population assay in glioma stem cell research. Brain Pathol 20:877–889. doi:10.1111/j.1750-3639.2010.00379.x
    • (2010) Brain Pathol , vol.20 , pp. 877-889
    • Wan, F.1    Zhang, S.2    Xie, R.3    Gao, B.4    Campos, B.5    Herold-Mende, C.6    Lei, T.7
  • 18
    • 33845988686 scopus 로고    scopus 로고
    • Neurosphere assays: growth factors and hormone differences in tumor and nontumor studies
    • COI: 1:CAS:528:DC%2BD2sXkslCrtw%3D%3D, PID: 16945995
    • Chaichana K, Zamora-Berridi G, Camara-Quintana J, Quinones-Hinojosa A (2006) Neurosphere assays: growth factors and hormone differences in tumor and nontumor studies. Stem Cells 24:2851–2857. doi:10.1634/stemcells.2006-0399
    • (2006) Stem Cells , vol.24 , pp. 2851-2857
    • Chaichana, K.1    Zamora-Berridi, G.2    Camara-Quintana, J.3    Quinones-Hinojosa, A.4
  • 19
    • 22244433866 scopus 로고    scopus 로고
    • Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2− cancer cells are similarly tumorigenic
    • COI: 1:CAS:528:DC%2BD2MXmt1egsrk%3D, PID: 16024622
    • Patrawala L, Calhoun T, Schneider-Broussard R, Zhou J, Claypool K, Tang DG (2005) Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2− cancer cells are similarly tumorigenic. Cancer Res 65:6207–6219. doi:10.1158/0008-5472.CAN-05-0592
    • (2005) Cancer Res , vol.65 , pp. 6207-6219
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3    Zhou, J.4    Claypool, K.5    Tang, D.G.6
  • 21
    • 84873410837 scopus 로고    scopus 로고
    • Glioblastoma cancer stem cells: role of the microenvironment and therapeutic targeting
    • COI: 1:CAS:528:DC%2BC38XhsFymur%2FF, PID: 23063412
    • Persano L, Rampazzo E, Basso G, Viola G (2013) Glioblastoma cancer stem cells: role of the microenvironment and therapeutic targeting. Biochem Pharmacol 85:612–622. doi:10.1016/j.bcp.2012.10.001
    • (2013) Biochem Pharmacol , vol.85 , pp. 612-622
    • Persano, L.1    Rampazzo, E.2    Basso, G.3    Viola, G.4
  • 23
    • 79953813644 scopus 로고    scopus 로고
    • Glioblastoma stem cells
    • PID: 21253762
    • Tabatabai G, Weller M (2011) Glioblastoma stem cells. Cell Tissue Res 343:459–465. doi:10.1007/s00441-010-1123-0
    • (2011) Cell Tissue Res , vol.343 , pp. 459-465
    • Tabatabai, G.1    Weller, M.2
  • 27
    • 75949101677 scopus 로고    scopus 로고
    • ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients’ outcome
    • COI: 1:CAS:528:DC%2BC3cXht1Kqs7g%3D, PID: 20010854
    • Li T, Su Y, Mei Y, Leng Q, Leng B, Liu Z, Stass SA, Jiang F (2010) ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients’ outcome. Lab Invest 90:234–244. doi:10.1038/labinvest.2009.127
    • (2010) Lab Invest , vol.90 , pp. 234-244
    • Li, T.1    Su, Y.2    Mei, Y.3    Leng, Q.4    Leng, B.5    Liu, Z.6    Stass, S.A.7    Jiang, F.8
  • 28
    • 65949112714 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
    • COI: 1:CAS:528:DC%2BD1MXksV2hsb0%3D, PID: 19336570
    • Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, Fields JZ, Wicha MS, Boman BM (2009) Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res 69:3382–3389. doi:10.1158/0008-5472.CAN-08-4418
    • (2009) Cancer Res , vol.69 , pp. 3382-3389
    • Huang, E.H.1    Hynes, M.J.2    Zhang, T.3    Ginestier, C.4    Dontu, G.5    Appelman, H.6    Fields, J.Z.7    Wicha, M.S.8    Boman, B.M.9
  • 29
    • 65249133087 scopus 로고    scopus 로고
    • AMP-activated protein kinase is involved in neural stem cell growth suppression and cell cycle arrest by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and glucose deprivation by down-regulating phospho-retinoblastoma protein and cyclin D
    • COI: 1:CAS:528:DC%2BD1MXisVSkt70%3D, PID: 19144636
    • Zang Y, Yu LF, Nan FJ, Feng LY, Li J (2009) AMP-activated protein kinase is involved in neural stem cell growth suppression and cell cycle arrest by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and glucose deprivation by down-regulating phospho-retinoblastoma protein and cyclin D. J Biol Chem 284:6175–6184. doi:10.1074/jbc.M806887200
    • (2009) J Biol Chem , vol.284 , pp. 6175-6184
    • Zang, Y.1    Yu, L.F.2    Nan, F.J.3    Feng, L.Y.4    Li, J.5
  • 31
    • 84867895444 scopus 로고    scopus 로고
    • Epigallocathechin gallate, polyphenol present in green tea, inhibits stem-like characteristics and epithelial-mesenchymal transition in nasopharyngeal cancer cell lines
    • COI: 1:CAS:528:DC%2BC3sXmt1Gks70%3D, PID: 23110507
    • Lin CH, Shen YA, Hung PH, Yu YB, Chen YJ (2012) Epigallocathechin gallate, polyphenol present in green tea, inhibits stem-like characteristics and epithelial-mesenchymal transition in nasopharyngeal cancer cell lines. BMC Complement Altern Med 12:201. doi:10.1186/1472-6882-12-201
    • (2012) BMC Complement Altern Med , vol.12 , pp. 201
    • Lin, C.H.1    Shen, Y.A.2    Hung, P.H.3    Yu, Y.B.4    Chen, Y.J.5
  • 32
    • 84884901283 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate attenuates head and neck cancer stem cell traits through suppression of Notch pathway
    • Lee SH, Nam HJ, Kang HJ, Kwon HW, Lim YC (2013) Epigallocatechin-3-gallate attenuates head and neck cancer stem cell traits through suppression of Notch pathway. Eur J Cancer. doi:10.1016/j.ejca.2013.06.025
    • (2013) Eur J Cancer
    • Lee, S.H.1    Nam, H.J.2    Kang, H.J.3    Kwon, H.W.4    Lim, Y.C.5
  • 33
    • 84862783302 scopus 로고    scopus 로고
    • Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells
    • COI: 1:CAS:528:DC%2BC38XkvFSrsLc%3D, PID: 22459208
    • Chen D, Pamu S, Cui Q, Chan TH, Dou QP (2012) Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells. Bioorg Med Chem 20:3031–3037. doi:10.1016/j.bmc.2012.03.002
    • (2012) Bioorg Med Chem , vol.20 , pp. 3031-3037
    • Chen, D.1    Pamu, S.2    Cui, Q.3    Chan, T.H.4    Dou, Q.P.5
  • 34
    • 84860214416 scopus 로고    scopus 로고
    • Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics
    • COI: 1:CAS:528:DC%2BC38XlslyrsLY%3D, PID: 21796625
    • Tang SN, Fu J, Nall D, Rodova M, Shankar S, Srivastava RK (2012) Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics. Int J Cancer 131:30–40. doi:10.1002/ijc.26323
    • (2012) Int J Cancer , vol.131 , pp. 30-40
    • Tang, S.N.1    Fu, J.2    Nall, D.3    Rodova, M.4    Shankar, S.5    Srivastava, R.K.6
  • 35
    • 77955641868 scopus 로고    scopus 로고
    • The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition
    • PID: 20718984
    • Tang SN, Singh C, Nall D, Meeker D, Shankar S, Srivastava RK (2010) The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition. J Mol Signal 5:14. doi:10.1186/1750-2187-5-14
    • (2010) J Mol Signal , vol.5 , pp. 14
    • Tang, S.N.1    Singh, C.2    Nall, D.3    Meeker, D.4    Shankar, S.5    Srivastava, R.K.6
  • 36
    • 79952440161 scopus 로고    scopus 로고
    • Epigallocatechin gallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor
    • PID: 21300025
    • Van Aller GS, Carson JD, Tang W, Peng H, Zhao L, Copeland RA, Tummino PJ, Luo L (2011) Epigallocatechin gallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor. Biochem Biophys Res Commun 406:194–199. doi:10.1016/j.bbrc.2011.02.010
    • (2011) Biochem Biophys Res Commun , vol.406 , pp. 194-199
    • Van Aller, G.S.1    Carson, J.D.2    Tang, W.3    Peng, H.4    Zhao, L.5    Copeland, R.A.6    Tummino, P.J.7    Luo, L.8
  • 37
    • 84861551579 scopus 로고    scopus 로고
    • ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines
    • COI: 1:CAS:528:DC%2BC38XotlWltrs%3D, PID: 22393246
    • Premkumar DR, Jane EP, DiDomenico JD, Vukmer NA, Agostino NR, Pollack IF (2012) ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines. J Pharmacol Exp Ther 341:859–872. doi:10.1124/jpet.112.191536
    • (2012) J Pharmacol Exp Ther , vol.341 , pp. 859-872
    • Premkumar, D.R.1    Jane, E.P.2    DiDomenico, J.D.3    Vukmer, N.A.4    Agostino, N.R.5    Pollack, I.F.6
  • 38
    • 79960798062 scopus 로고    scopus 로고
    • Proteomic approaches to study epigallocatechin gallate-provoked apoptosis of TSGH-8301 human urinary bladder carcinoma cells: roles of AKT and heat shock protein 27-modulated intrinsic apoptotic pathways
    • COI: 1:CAS:528:DC%2BC3MXhtF2jsbbF, PID: 21743966
    • Chen NG, Lu CC, Lin YH, Shen WC, Lai CH, Ho YJ, Chung JG, Lin TH, Lin YC, Yang JS (2011) Proteomic approaches to study epigallocatechin gallate-provoked apoptosis of TSGH-8301 human urinary bladder carcinoma cells: roles of AKT and heat shock protein 27-modulated intrinsic apoptotic pathways. Oncol Rep 26:939–947. doi:10.3892/or.2011.1377
    • (2011) Oncol Rep , vol.26 , pp. 939-947
    • Chen, N.G.1    Lu, C.C.2    Lin, Y.H.3    Shen, W.C.4    Lai, C.H.5    Ho, Y.J.6    Chung, J.G.7    Lin, T.H.8    Lin, Y.C.9    Yang, J.S.10
  • 39
    • 84864433190 scopus 로고    scopus 로고
    • Pro-apoptotic effect of epigallo-catechin-3-gallate on B lymphocytes through regulating BAFF/PI3 K/Akt/mTOR signaling in rats with collagen-induced arthritis
    • COI: 1:CAS:528:DC%2BC38XhtVOlsLfL, PID: 22760071
    • Liu D, Li P, Song S, Liu Y, Wang Q, Chang Y, Wu Y, Chen J, Zhao W, Zhang L, Wei W (2012) Pro-apoptotic effect of epigallo-catechin-3-gallate on B lymphocytes through regulating BAFF/PI3 K/Akt/mTOR signaling in rats with collagen-induced arthritis. Eur J Pharmacol 690:214–225. doi:10.1016/j.ejphar.2012.06.026
    • (2012) Eur J Pharmacol , vol.690 , pp. 214-225
    • Liu, D.1    Li, P.2    Song, S.3    Liu, Y.4    Wang, Q.5    Chang, Y.6    Wu, Y.7    Chen, J.8    Zhao, W.9    Zhang, L.10    Wei, W.11
  • 40
    • 80055026027 scopus 로고    scopus 로고
    • Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through the GSK-3beta/beta-catenin signaling pathway
    • COI: 1:CAS:528:DC%2BC3MXhsV2jsrnI, PID: 22046442
    • Li C, Zhou C, Wang S, Feng Y, Lin W, Lin S, Wang Y, Huang H, Liu P, Mu YG, Shen X (2011) Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through the GSK-3beta/beta-catenin signaling pathway. PLoS One 6:e27053. doi:10.1371/journal.pone.0027053
    • (2011) PLoS One , vol.6 , pp. 27053
    • Li, C.1    Zhou, C.2    Wang, S.3    Feng, Y.4    Lin, W.5    Lin, S.6    Wang, Y.7    Huang, H.8    Liu, P.9    Mu, Y.G.10    Shen, X.11
  • 41
    • 33645059697 scopus 로고    scopus 로고
    • The small organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death
    • COI: 1:CAS:528:DC%2BD28XhvV2gsbs%3D, PID: 16510597
    • Manero F, Gautier F, Gallenne T, Cauquil N, Gree D, Cartron PF, Geneste O, Gree R, Vallette FM, Juin P (2006) The small organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death. Cancer Res 66:2757–2764. doi:10.1158/0008-5472.CAN-05-2097
    • (2006) Cancer Res , vol.66 , pp. 2757-2764
    • Manero, F.1    Gautier, F.2    Gallenne, T.3    Cauquil, N.4    Gree, D.5    Cartron, P.F.6    Geneste, O.7    Gree, R.8    Vallette, F.M.9    Juin, P.10
  • 42
    • 70349296853 scopus 로고    scopus 로고
    • The ABCG2 resistance network of glioblastoma
    • PID: 19713741
    • Bleau AM, Huse JT, Holland EC (2009) The ABCG2 resistance network of glioblastoma. Cell Cycle 8:2936–2944
    • (2009) Cell Cycle , vol.8 , pp. 2936-2944
    • Bleau, A.M.1    Huse, J.T.2    Holland, E.C.3
  • 43
    • 31544464704 scopus 로고    scopus 로고
    • Targeted modulation of MGMT: clinical implications
    • COI: 1:CAS:528:DC%2BD28XmtlGqtg%3D%3D, PID: 16428468
    • Liu L, Gerson SL (2006) Targeted modulation of MGMT: clinical implications. Clin Cancer Res 12:328–331. doi:10.1158/1078-0432.CCR-05-2543
    • (2006) Clin Cancer Res , vol.12 , pp. 328-331
    • Liu, L.1    Gerson, S.L.2
  • 45
    • 84863665388 scopus 로고    scopus 로고
    • Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells
    • PID: 22701311
    • Ryu CH, Yoon WS, Park KY, Kim SM, Lim JY, Woo JS, Jeong CH, Hou Y, Jeun SS (2012) Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells. J Biomed Biotechnol 2012:987495. doi:10.1155/2012/987495
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 987495
    • Ryu, C.H.1    Yoon, W.S.2    Park, K.Y.3    Kim, S.M.4    Lim, J.Y.5    Woo, J.S.6    Jeong, C.H.7    Hou, Y.8    Jeun, S.S.9
  • 46
    • 79951577565 scopus 로고    scopus 로고
    • Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models
    • COI: 1:CAS:528:DC%2BC3MXit1Kjsb4%3D, PID: 21257259
    • Chen TC, Wang W, Golden EB, Thomas S, Sivakumar W, Hofman FM, Louie SG, Schonthal AH (2011) Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models. Cancer Lett 302:100–108. doi:10.1016/j.canlet.2010.11.008
    • (2011) Cancer Lett , vol.302 , pp. 100-108
    • Chen, T.C.1    Wang, W.2    Golden, E.B.3    Thomas, S.4    Sivakumar, W.5    Hofman, F.M.6    Louie, S.G.7    Schonthal, A.H.8
  • 47
    • 15744403992 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein function and reversal of multidrug resistance by (−)-epigallocatechin gallate in human cancer cells
    • COI: 1:CAS:528:DC%2BD2MXivVSnsLg%3D, PID: 15795098
    • Qian F, Wei D, Zhang Q, Yang S (2005) Modulation of P-glycoprotein function and reversal of multidrug resistance by (−)-epigallocatechin gallate in human cancer cells. Biomed Pharmacother 59:64–69. doi:10.1016/j.biopha.2005.01.002
    • (2005) Biomed Pharmacother , vol.59 , pp. 64-69
    • Qian, F.1    Wei, D.2    Zhang, Q.3    Yang, S.4
  • 49
    • 0037196568 scopus 로고    scopus 로고
    • Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols
    • COI: 1:CAS:528:DC%2BD38Xhtlersbg%3D, PID: 11853888
    • Jodoin J, Demeule M, Beliveau R (2002) Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols. Biochim Biophys Acta 1542:149–159
    • (2002) Biochim Biophys Acta , vol.1542 , pp. 149-159
    • Jodoin, J.1    Demeule, M.2    Beliveau, R.3
  • 50
    • 84891858084 scopus 로고    scopus 로고
    • Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/beta-catenin pathway
    • PID: 23897632
    • Riganti C, Salaroglio IC, Caldera V, Campia I, Kopecka J, Mellai M, Annovazzi L, Bosia A, Ghigo D, Schiffer D (2013) Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/beta-catenin pathway. Neuro Oncol. doi:10.1093/neuonc/not104
    • (2013) Neuro Oncol
    • Riganti, C.1    Salaroglio, I.C.2    Caldera, V.3    Campia, I.4    Kopecka, J.5    Mellai, M.6    Annovazzi, L.7    Bosia, A.8    Ghigo, D.9    Schiffer, D.10


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