Pro-apoptotic effect of Epigallo-catechin-3-gallate on B lymphocytes through regulating BAFF/PI3K/Akt/mTOR signaling in rats with collagen-induced arthritis

European Journal of Pharmacology

Volumn 690, Issue 1-3, 2012, Pages 214-225

  Liu, Dandan ^a   Li, Peipei ^a   Song, Shanshan ^a   Liu, Yunjie ^a   Wang, Qingtong ^a   Chang, Yan ^a   Wu, Yujing ^a   Chen, Jingyu ^a   Zhao, Wendi ^a   Zhang, Lingling ^a   Wei, Wei ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; B lymphocytes; Collagen induced arthritis; Epigallo catechin 3 gallate; PI3K Akt mTOR signaling

Indexed keywords

B CELL ACTIVATING FACTOR; B CELL ACTIVATING FACTOR RECEPTOR; BIM PROTEIN; COLLAGEN ANTIBODY; COLLAGEN TYPE 2 ANTIBODY; EPIGALLOCATECHIN GALLATE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PAEONIFLORIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN P110; PROTEIN P110 DELTA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTHRITIS; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DRUG EFFECT; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; ANKLE JOINT; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ARTHRITIS, EXPERIMENTAL; B-CELL ACTIVATING FACTOR; B-CELL ACTIVATION FACTOR RECEPTOR; B-LYMPHOCYTES; BCL-X PROTEIN; CATECHIN; CELL PROLIFERATION; COLLAGEN TYPE II; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IMMUNOGLOBULIN ISOTYPES; MALE; MEMBRANE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPLEEN; TOR SERINE-THREONINE KINASES;

EID: 84864433190     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.06.026     Document Type: Article

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