(-)-Epigallocatechin-3-gallate downregulates Pg-P and BCRP in a tamoxifen resistant MCF-7 cell line

Phytomedicine

Volumn 17, Issue 5, 2010, Pages 356-362

  Farabegoli, F ^a   Papi, A ^a   Bartolini, G ^a   Ostan, R ^b   Orlandi, M ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

BCRP; Breast carcinoma; Green tea; MRP1; P gp; Tamoxifen

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; EPIGALLOCATECHIN GALLATE; GLYCOPROTEIN P; MESSENGER RNA; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN BAX; PROTEIN BCL 2; TAMOXIFEN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CELL STRAIN MCF 7; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; GROWTH INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSCRIPTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ATP-BINDING CASSETTE TRANSPORTERS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CAMELLIA SINENSIS; CATECHIN; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION; HUMANS; LEUPEPTINS; MITOXANTRONE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; P-GLYCOPROTEIN; PLANT EXTRACTS; PROTEASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; TAMOXIFEN;

EID: 76749101143     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.01.001     Document Type: Article

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