Reduced curvature of ligand-binding domain free-energy surface underlies partial agonism at NMDA receptors

Structure

Volumn 23, Issue 1, 2015, Pages 228-236

  Dai, Jian ^a   Zhou, Huan Xiang ^a  

^a Florida State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUN1 RECEPTOR; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PARTIAL AGONIST; UNCLASSIFIED DRUG; LIGAND; PROTEIN BINDING;

ARTICLE; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; FREE ENERGY SURFACE; LIGAND BINDING; PARTIAL AGONISM; PRIORITY JOURNAL; PROTEIN CONFORMATION; AGONISTS; BINDING SITE; CHEMISTRY; COMPUTER SIMULATION; METABOLISM; MOLECULAR MODEL; PROTEIN TERTIARY STRUCTURE;

BINDING SITES; COMPUTER SIMULATION; DRUG PARTIAL AGONISM; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84920987371     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2014.11.012     Document Type: Article

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