Mechanism of partial agonism at the GluR2 AMPA receptor: Measurements of lobe orientation in solution

Biochemistry

Volumn 47, Issue 40, 2008, Pages 10600-10610

  Maltsev, Alexander S ^a   Ahmed, Ahmed H ^a   Fenwick, Michael K ^a   Jane, David E ^b   Oswald, Robert E ^a  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MECHANISMS; MOLECULAR BIOLOGY; MOLECULAR ORIENTATION; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POWDERS;

AGONISM; AMPA-RECEPTOR; BINDING DOMAIN; CHANNEL ACTIVATION; CHANNEL OPENING; CRYSTAL PACKINGS; CRYSTALLIZATION CONDITIONS; IONOTROPIC GLUTAMATE RECEPTORS; NMR SPECTROS COPY; RESIDUAL DIPOLAR COUPLINGS; SOLUTION CONFORMATIONS; STRUCTURAL CHANGES;

CRYSTAL STRUCTURE;

3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 2 HYDROXY 1 PROPANESULFONIC ACID; AMPA RECEPTOR; GLUTAMATE RECEPTOR 2; GLUTAMIC ACID; HEXANOL; KAINIC ACID; PARTIAL AGONIST; WILLARDIINE; ZINC;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG BINDING SITE; DRUG RECEPTOR BINDING; HYDROGEN BOND; NERVE CELL PLASTICITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN PURIFICATION; RECEPTOR DOWN REGULATION;

ALANINE; ANIMALS; CRYSTALLOGRAPHY, X-RAY; GLUTAMIC ACID; KAINIC ACID; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, AMPA; SOLUTIONS; URACIL;

EID: 53249115359     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800843c     Document Type: Article

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