Apoptosis of beta cells in diabetes mellitus

DNA and Cell Biology

Volumn 33, Issue 11, 2014, Pages 743-748

  Anuradha, Rachakatla ^a   Saraswati, Mudigonda ^a   Kumar, Kishore G ^a   Rani, Surekha H ^a  

^a OSMANIA UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; ANTIOXIDANT;

ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; DIABETES MELLITUS; DRUG TARGETING; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; HYPERGLYCEMIA; MOLECULAR PATHOLOGY; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REVIEW; GENETIC PREDISPOSITION; GENETICS; METABOLISM;

ANTIOXIDANTS; APOPTOSIS; DIABETES MELLITUS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN-SECRETING CELLS;

EID: 84920814282     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2014.2352     Document Type: Review

References (50)

1. Allen, D. A. , Yaqoob, M. M. , and Harwood, S. M. (2005). Mechanisms of high glucose-induced apoptosis and its relationship to diabetic complications. J Nutr Biochem 12, 705-713.
2. Babic, I. , Cherry, E. , and Fujita, D. J. (2006). SUMO modification of Sam68 enhances its ability to repress cyclin D1 expression and inhibits its ability to induce apoptosis. Oncogene 25, 4955-4964.
3. Bonora, E. (2008). Protection of pancreatic beta-cells: is it feasible. Nutr Metab Cardiovasc Dis 18, 74-83.
4. Bosca, L. , and Hortelano, S. (1999). Mechanisms of nitric oxidedependent apoptosis: involvement of mitochondrial mediators. Cell Signal 11, 239-244.
5. Cnop, M. , Welsh, N. , Jonas, J. C. , Jörns, A. , Lenzen, S. , and Eizirik, D. L. (2005). Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 54, S97-S107.
6. Dana, T. G. , Rongkun, L. , and Thomas, W. O. (2007). Diabetesenhanced inflammation and apoptosis-impact on periodontal pathosis. Periodontol 2000 45, 128-137.
7. Delphine, F. , and Pierre, B. (2011). T2DM: why epigenetics?. J Nutr Metab 2011, 17.
8. Dickson, L. M. , and Rhodes, C. J. (2004). Pancreatic B-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt. Am J Physiol Endocrinol Metab 287, E192-E198.
9. Dotta, F. , Fondelli, C. , and Mario, U. D. (2005). Type 1 diabetes mellitus as a polygenicmultifactorial disease: immunopathogenic mechanisms of beta-cell destruction. Acta Biomed 76 Suppl 3, 14-18.
10. Drucker, D. J. (2003). Glucagon-like peptide-1 and the islet beta-cell: augmentation of cell proliferation and inhibition of apoptosis. Endocrinology 144, 5145-5148.
11. Eizirik, D. L. , and Mandrup-Poulen, T. (2001). A choice of death-the signal-transduction of immune-mediated b-cell apoptosis. Diabetologia 44, 2115-2213.
12. Evans, J. C. , Frayling, T. M. , Cassell, P. G. , Saker, P. J. , Hitman, G. A. , Walker, M. , Levy, J. C. , Stephen, ORahill, S. , Rao, P. V. , Bennett, A. J. , Jones, E. C. , Menzel, S. , Prestwich, P. , Simecek, N. , Wishart, M. , Dhillon, R. , Fletcher, C. , Millward, A. , Demaine, A. , Wilkin, T. , Horikawa, Y. , Cox, N. J. , Bell, G. I. , Ellard, S. , McCarthy, M. I. , and Hattersley, A. T. (2001). Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom. Am J Hum Genet 69, 544-552.
13. Evans, J. L. , Goldfine, I. D. , Maddux, B. A. , and Grodsky, G. M. (2002). Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 23, 599-622.
14. Francés, D. E. , Ronco, M. T. , Monti, J. A. , Ingaramo, P. I. , Pisani, G. B. , Parody, J. P. , Pellegrino, J. M. , Sanz, P. M. , Carrillo, M. C. , and Carnovale, C. E. (2010). Hyperglycemia induces apoptosis in rat liver through the increase of hydroxyl radical: new insights into the insulin effect. J Endocrinol 205, 187-200.
15. Garber, A. J. (2011). Long-acting glucagon-like peptide 1 receptor agonists: a review of their efficacy and tolerability. Diabetes Care 34 Suppl 2, S279-S284.
16. Garcia-Bailo, B. , El-Sohemy, A. , Haddad, P. S. , Arora, P. , Benzaied, F. , Karmali, M. , and Badawi, A. (2011). Vitamins D, C, and E in the prevention of type 2 diabetes mellitus: mod-ulation of inflammation and oxidative stress. Biologics 5, 7-19.
17. Halban, P. A. , Polonsky, K. S. , Bowden, D. W. , Hawkins, M. A. , Ling, C. , Mather, K. J. , Powers, A. C. , Rhodes, C. J. , Sussel, L. , and Weir, G. C. (2014). b-Cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. J Clin Endocrinol Metab 6, 1983-1992.
18. Inge, A. M. , Van den, O. , Hennie, G. R. , Mike, T. N. , and Suat, S. (2010). Endothelial dysfunction, inflammation, and apoptosis in diabetes mellitus. Mediators Inflamm 2010, 1-15.
19. Jeanette, S. J. , Alex, K. H. , David, J. R. , and Adviye, E. (2005). Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovasc Diabetol 4, 5.
20. Jenny, B. , Carla, M. G. , Fabrica, M. , Andriano, M. , Daniel, J. D. , Piero, M. , Conny, G. , Chantal, M. , Gabriel, N. , Andrea, J. , Decio, L. E. , and Esteban, N. G. (2011). Cytokines tumor necrosis factor-alpha and interferon-c induce pancreatic b-cell apoptosis through STAT1-mediated Bim protein activation. J Biol Chem 286, 39632-39643.
21. Karmen, S. , Damir, B. , and Dragan, D. (2013). Genetic and epigenetic factors in etiology of diabetes mellitus type 1. Pediatrics 132, 1112-1122.
22. Kiely, A. , Mcclenaghan, N. H. , Flatt, P. R. , and Newsholme, P. (2007). Pro-inflammatory cytokines increase glucose, alanine and triacylglycerol utilization but inhibit insulin secretion in a clonal pancreatic beta-cell line. J Endocrinol 195, 113-123.
23. Kim, J. Y. , Lim, D. M. , Park, H. S. , Moon, C. I. , Choi, K. J. , Lee, S. K. , Baik, H. W. , Park, K. Y. , and Kim, B. J. (2012). Exendin-4 protects against sulfonylurea-induced b-cell apoptosis. J Pharmacol Sci 118, 65-74.
24. Kitamura, T. (2013). The role of FOXO1 in b-cell failure and type 2 diabetes mellitus. Nat Rev Endocrinol 10, 615-623.
25. Kitamura, T. , and Ido Kitamura, Y. (2007). Role of FoxO proteins in pancreatic b cells. Endocr J 54, 507-515.
26. Krijnen, P. A. J. , Simsek, S. , and Niessen, H. W. M. (2009). Apoptosis in diabetes. Apoptosis 14, 1387-1388.
27. Lam, V. K. , Ma, R. C. , Lee, H. M. , Hu, C. , Park, K. S. , Furuta, H. , Wang, Y. , Tam, C. H. , Sim, X. , Ng, D. P. , Liu, J. , Wong, T. Y. , Tai, E. S. , Morris, A. P. , Tang, N. L. , Woo, J. , Leung, P. C. , Kong, A. P. , Ozaki, R. , Jia, W. P. , Lee, H. K. , Nanjo, K. , Xu, G. , Ng, M. C. , So, W. Y. , and Chan, J. C. (2013). Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations. PLoS One 8, 6.
28. Larsen, C. M. , Faulenbach, M. , Vaag, A. , Volund, A. , Ehses, J. A. , Seifert, B. , Mandrup-Poulsen, T. , and Donath, M. Y. (2007). Interleukin-1 receptor antagonist in type 2 diabetes mellitus. N Engl J Med 356, 1517-1526.
29. Lee, S. C. , and Pervaiz, S. (2007). Apoptosis in the pathophysiology of diabetes mellitus. Int J Biochem Cell Biol 39, 497-504.
30. Leonardi, O. , Mints, G. , and Hussain, M. A. (2003). Beta-cell apoptosis in the pathogenesis of human type 2 diabetes mellitus. Eur J Endocrinol 149, 99-102.
31. Mandrup-Poulsen, T. (1996). The role of interleukin-1 in the pathogenesis of IDDM. Diabetologia 39, 1005-1029.
32. Mao, Y. , Ootaka, T. , Saito, T. , Sato, H. , Sato, T. , and Ito, S. (2003). The involvement of advanced glycation endproducts (AGEs) in renal injury of diabetic glomerulosclerosis: association with phenotypic change in renal cells and infiltration of immune cells. Clin Exp Nephrol 7, 201-209.
33. Marc, Y. D. , Desiree, M. S. , Mirjam, F. , Helga, E. , Aurel, P. , and Jan, A. E. (2008). Islet inflammation in type 2 diabetes. Diabetes Care 31, S161-S164.
34. Maria, A. F. , Susana, R. , Ana, F. , Zalba, G. , and Diéz, J. (2001). Cardiomyocyte apoptotic cell death in arterial hypertension mechanisms and potential management. Hypertension 38, 1406-1441.
35. Mee, L. , Nabokina, S. M. , Sekar, V. T. , Subramanian, V. S. , Maedler, K. , and Said, H. M. (2009). Pancreatic beta cells and islets take up thiamine by a regulated carrier-mediated process: studies using mice and human pancreatic preparations. Am J Physiol Gastrointest Liver Physiol 297, G197-G206.
36. Moriwaki, M. , Itoh, N. , Miyagawa, J. , Yamamoto, K. , Imagawa, A. , Yamagata, K. , Iwahashi, H. , Nakajima, H. , Namba, M. , Nagata, S. , Hanafusa, T. , and Matsuzawa, Y. (1999). Fas and Fas ligand expression in inflamed islets in pancreas sections of patients with recent-onset Type I diabetes mellitus. Diabetologia 42, 1332-1340.
37. Nick, G. , Willium, A. , Rudert, M. T. , and Paul, D. R. (2000). Protection of human islets from the effects of interleukin-1b by adenoviral gene transfer of an IkB repressor. J Biol Chem 275, 36509-36513.
38. Nolse, R. L. , Hamid, Y. H. , Pociot, F. , Paulsen, S. , Andersen, K. M. , Borch-Johnsen, K. , Drivshol, T. , Hansen, T. , Pedersen, O. , and Mandrup-Poulsen, T. (2006). Association of a microsatellite in FASL to type II diabetesand of the FAS-670G4A genotype to insulin resistance. Genes Immun 7, 316-321.
39. Perez-Bravo, F. , Carrasco, E. , Gutierrez-Lopez, M. D. , Martinez, M. T. , Lopez, G. , and de los Rios, M. G. (1996). Genetic predisposition and environmental factors leading to the development of insulin-dependent diabetes mellitus in Chilean children. J Mol Med Berl 4, 105-109.
40. Robertson, R. P. , Harmon, J. , Oanh, P. , Tran, T. , and Vincent, P. (2004). Cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes. Diabetes 1, 47-56.
41. Sakahira, H. , Enari, M. , and Nagata, S. (1998). Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391, 96-99.
42. Seshadria, K. G. , Bubblu, T. , and Amarabalan, R. (2011). Role of vitamin D in diabetes. Endocrinol Metab 1, 47-56.
43. Straub, S. G. , and Sharp, G. W. (2002). Glucose-stimulated signaling pathways in bipha-sic insulin secretion. Diabetes Metab Res Rev 18, 451-463.
44. Thiemermann, C. , McDonald, M. C. , and Cuzzocrea, S. (2001). The stable nitroxide, tempol, attenuates the effects of peroxynitrite and oxygen-derived free radicals. Crit Care Med 29, 223-224.
45. Van belle, T. L. , Coppieters, K. T. , and Von herrath, M. G. (2011). Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol Rev 91, 79-118.
46. Wajchenberg, B. L. (2007). Beta-cell failure in diabetes and preservation by clinical treatment. Endocr Rev 28, 187-218.
47. Wang, Y. , Tong, R. , Wu. , Cai, S. , Welte, T. , and Chin, Y. E. (2000). Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation. Mol Cell Biol 13, 4505-4512.
48. Wild, S. , Roglic, G. , Green, A. , Sicree, R. , and King, H. (2004). Global Prevalence of Diabetes Estimates for the year 2000 and projections for 2030. Diabetescare 27, 1047-1053.
49. Yang, X. , Stennicke, H. R. , Wang, B. , Green, D. R. , Janicke, R. U. , Srinivasan, A. , Seth, P. , Salvesen, G. S. , and Froelich, C. J. (1998). Granzyme B mimics apical caspases: description of a unified pathway for trans-activation of executioner caspase-3 and -7. J Biol Chem 273, 34278-34283.
50. Yang, Y. , Chang, B. H. , Samson, S. L. , Ming, V. , Li, and Chan, L. (2009). The Kruppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription. Nucleic Acids Res 37, 2529-2538.