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Volumn 20, Issue 6, 2010, Pages 316-320

Studying the effect of LPS on cytotoxicity and apoptosis in PC12 neuronal cells: Role of Bax, Bcl-2, and Caspase-3 protein expression

Author keywords

Apoptosis; Bax; Bcl2; Caspase; Cytotoxicity; LPS

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BACTERIUM LIPOPOLYSACCHARIDE; BETA ACTIN; CASPASE 3; ENDOTOXIN; PROCASPASE 3; PROTEIN BAX; PROTEIN BCL 2;

EID: 77953805193     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376516.2010.486420     Document Type: Article
Times cited : (44)

References (26)
  • 1
    • 10944234609 scopus 로고    scopus 로고
    • Neurotoxic effects of lipopolysaccharide on nigral dopaminergic neurons are mediated by microglial activation, interleukin-1beta, and expression of caspase-11 in mice
    • Arai H, Furuya T, Yasuda T, Miura M, Mizuno Y, Mochizuki H. 2004. Neurotoxic effects of lipopolysaccharide on nigral dopaminergic neurons are mediated by microglial activation, interleukin-1beta, and expression of caspase-11 in mice. J Biol Chem 279:51647-141653
    • (2004) J Biol Chem , vol.279 , pp. 51647-141653
    • Arai, H.1    Furuya, T.2    Yasuda, T.3    Miura, M.4    Mizuno, Y.5    Mochizuki, H.6
  • 2
    • 0035146889 scopus 로고    scopus 로고
    • Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function
    • Barger SW, Basile AS. 2001. Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function. J Neurochem 76:846-854.
    • (2001) J Neurochem , vol.76 , pp. 846-854
    • Barger, S.W.1    Basile, A.S.2
  • 3
    • 0026738695 scopus 로고
    • Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
    • Chao CC, Hu S, Molitor TW, Shaskan EG, Peterson PK. 1992. Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J Immunol 149:2736-2741.
    • (1992) J Immunol , vol.149 , pp. 2736-2741
    • Chao, C.C.1    Hu, S.2    Molitor, T.W.3    Shaskan, E.G.4    Peterson, P.K.5
  • 4
    • 0028089896 scopus 로고
    • Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures
    • Dawson VL, Brahmbhatt HP, Mong JA, Dawson TM. 1994. Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures. Neuropharmacology 33:1425-1430.
    • (1994) Neuropharmacology , vol.33 , pp. 1425-1430
    • Dawson, V.L.1    Brahmbhatt, H.P.2    Mong, J.A.3    Dawson, T.M.4
  • 5
    • 33847698059 scopus 로고    scopus 로고
    • Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages
    • Emre Y, Hurtaud C, Nubel T, Criscuolo F, Ricquier D, Cassard-Doulcier AM. 2007. Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages. Biochem J 402:271-278.
    • (2007) Biochem J , vol.402 , pp. 271-278
    • Emre, Y.1    Hurtaud, C.2    Nubel, T.3    Criscuolo, F.4    Ricquier, D.5    Cassard-Doulcier, A.M.6
  • 6
    • 28244442462 scopus 로고    scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in human disease
    • Fadeel B, Orrenius S. 2005. Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease. J Intern Med 258:479-517.
    • (2005) J Intern Med , vol.258 , pp. 479-517
    • Fadeel, B.1    Orrenius, S.2
  • 7
    • 0037417220 scopus 로고    scopus 로고
    • Apoptosis and caspases in neurodegenerative diseases
    • Friedlander RM. 2003. Apoptosis and caspases in neurodegenerative diseases. N Engl J Med 348:1365-1375.
    • (2003) N Engl J Med , vol.348 , pp. 1365-1375
    • Friedlander, R.M.1
  • 8
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene LA, Tischler AS. 1976. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 73:2424-2428.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 9
    • 2642605346 scopus 로고    scopus 로고
    • Induction of nitric oxide synthase and nitric oxidemediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/ lipopolysaccharide
    • Heneka MT, Loschmann PA, Gleichmann M, Weller M, Schulz JB, Wullner U, Klockgether T. 1998. Induction of nitric oxide synthase and nitric oxidemediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharide. J Neurochem 71:88-94.
    • (1998) J Neurochem , vol.71 , pp. 88-94
    • Heneka, M.T.1    Loschmann, P.A.2    Gleichmann, M.3    Weller, M.4    Schulz, J.B.5    Wullner, U.6    Klockgether, T.7
  • 10
    • 33645910880 scopus 로고    scopus 로고
    • Salmonella lipopolysaccharide (LPS) mediated neurodegeneration in hippocampal slice cultures
    • Johansson S, Bohman S, Radesäter AC, Oberg C, Luthman J. 2005. Salmonella lipopolysaccharide (LPS) mediated neurodegeneration in hippocampal slice cultures. Neurotox Res 8:207-220.
    • (2005) Neurotox Res , vol.8 , pp. 207-220
    • Johansson, S.1    Bohman, S.2    Radesäter, A.C.3    Oberg, C.4    Luthman, J.5
  • 11
    • 2342502556 scopus 로고    scopus 로고
    • Neuronal apoptosis in neurodegenerative diseases: From basic research to clinical application
    • Kermer P, Liman J, Weishaupt JH, Bahr M. 2004. Neuronal apoptosis in neurodegenerative diseases: from basic research to clinical application. Neurodegener Dis 1:9-19.
    • (2004) Neurodegener Dis , vol.1 , pp. 9-19
    • Kermer, P.1    Liman, J.2    Weishaupt, J.H.3    Bahr, M.4
  • 12
    • 0034663061 scopus 로고    scopus 로고
    • Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: Role of microglia
    • Kim WG, Mohney RP, Wilson B, Jeohn GH, Liu B, Hong JS. 2000. Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J Neurosci 20:6309-6316.
    • (2000) J Neurosci , vol.20 , pp. 6309-6316
    • Kim, W.G.1    Mohney, R.P.2    Wilson, B.3    Jeohn, G.H.4    Liu, B.5    Hong, J.S.6
  • 13
    • 26444560960 scopus 로고    scopus 로고
    • Caspases: Pharmacological manipulation of cell death
    • Lavrik IN, Golks A, Krammer PH. 2005. Caspases: pharmacological manipulation of cell death. J Clin Invest 115:2665-2672.
    • (2005) J Clin Invest , vol.115 , pp. 2665-2672
    • Lavrik, I.N.1    Golks, A.2    Krammer, P.H.3
  • 14
    • 0037336701 scopus 로고    scopus 로고
    • Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway
    • Li Y, Liu L, Barger SW, Griffin WS. 2003. Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway. J Neurosci 23:1605-1611.
    • (2003) J Neurosci , vol.23 , pp. 1605-1611
    • Li, Y.1    Liu, L.2    Barger, S.W.3    Griffin, W.S.4
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 16
    • 33749036329 scopus 로고    scopus 로고
    • Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase
    • Qian L, Block ML, Wei SJ, Lin CF, Reece J, Pang H, Wilson B, Hong JS, Flood PM. 2006. Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase. J Pharmacol Exp Ther 319:44-52.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 44-52
    • Qian, L.1    Block, M.L.2    Wei, S.J.3    Lin, C.F.4    Reece, J.5    Pang, H.6    Wilson, B.7    Hong, J.S.8    Flood, P.M.9
  • 17
    • 33947512343 scopus 로고    scopus 로고
    • Neurotoxins and neurotoxicity mechanisms. An overview
    • Segura-Aguilar J, Kostrzewa RM. 2006. Neurotoxins and neurotoxicity mechanisms. An overview. Neurotox Res 10:263-287.
    • (2006) Neurotox Res , vol.10 , pp. 263-287
    • Segura-Aguilar, J.1    Kostrzewa, R.M.2
  • 20
    • 65749118790 scopus 로고    scopus 로고
    • Involvement of caspase-8, -9, and -3 in high glucose-induced apoptosis in PC12 cells
    • Sharifi AM, Eslami H, Larijani B, Davoodi J. 2009. Involvement of caspase-8, -9, and -3 in high glucose-induced apoptosis in PC12 cells. Neurosci Lett 459:47-51.
    • (2009) Neurosci Lett , vol.459 , pp. 47-51
    • Sharifi, A.M.1    Eslami, H.2    Larijani, B.3    Davoodi, J.4
  • 21
    • 38549178321 scopus 로고    scopus 로고
    • Studying the effects of lead on DNA fragmentation and proapoptotic Bax and antiapoptotic Bcl-2 protein expression in PC12 cells
    • Sharifi AM, Mousavi, SH. 2008. Studying the effects of lead on DNA fragmentation and proapoptotic Bax and antiapoptotic Bcl-2 protein expression in PC12 cells. Toxicol Mech Meth 18:75-79.
    • (2008) Toxicol Mech Meth , vol.18 , pp. 75-79
    • Sharifi, A.M.1    Mousavi, S.H.2
  • 23
    • 34547231622 scopus 로고    scopus 로고
    • Study of high glucose-induced apoptosis in PC12 cells: Role of bax protein
    • Sharifi AM, Mousavi SH, Farhadi M, Larijani B. 2007. Study of high glucose-induced apoptosis in PC12 cells: role of bax protein. J Pharmacol Sci 104:258-262.
    • (2007) J Pharmacol Sci , vol.104 , pp. 258-262
    • Sharifi, A.M.1    Mousavi, S.H.2    Farhadi, M.3    Larijani, B.4
  • 24
    • 0032168790 scopus 로고    scopus 로고
    • Apoptosis in vasculature of spontaneously hypertensive rats: Effect of an angiotensin converting enzyme inhibitor and a calcium channel antagonist
    • Sharifi AM, Schiffrin EL. 1998. Apoptosis in vasculature of spontaneously hypertensive rats: effect of an angiotensin converting enzyme inhibitor and a calcium channel antagonist. Am J Hypertens 11:1108-1116.
    • (1998) Am J Hypertens , vol.11 , pp. 1108-1116
    • Sharifi, A.M.1    Schiffrin, E.L.2
  • 25
    • 0041430632 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: Role of inducible nitric oxide synthase and protection by indomethacin
    • Shibata H, Katsuki H, Nishiwaki M, Kume T, Kaneko S, Akaike A. 2003. Lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: role of inducible nitric oxide synthase and protection by indomethacin. J Neurochem 86:1201-1212.
    • (2003) J Neurochem , vol.86 , pp. 1201-1212
    • Shibata, H.1    Katsuki, H.2    Nishiwaki, M.3    Kume, T.4    Kaneko, S.5    Akaike, A.6
  • 26
    • 27644568975 scopus 로고    scopus 로고
    • Involvement of proinflammatory factors, apoptosis, caspase-3 activation and Ca2+ disturbance in microglia activation-mediated dopaminergic cell degeneration
    • Wang X, Chen S, Ma G, Ye M, Lu G. 2005. Involvement of proinflammatory factors, apoptosis, caspase-3 activation and Ca2+ disturbance in microglia activation-mediated dopaminergic cell degeneration. Mech Ageing Dev 126:1241-1254.
    • (2005) Mech Ageing Dev , vol.126 , pp. 1241-1254
    • Wang, X.1    Chen, S.2    Ma, G.3    Ye, M.4    Lu, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.