Monosialoanglioside (GM1) prevents lead-induced neurotoxicity on long-term potentiation, SOD activity, MDA levels, and intracellular calcium levels of hippocampus in rats

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 379, Issue 5, 2009, Pages 517-524

  She, Jia Qi ^a   Wang, Ming ^a   Zhu, Da Miao ^a   Tang, Mingliang ^a   Chen, Ju Tao ^a   Wang, Lang ^a   Ruan, Di Yun ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Antioxidant system; Ganglioside GM1; Internal calcium levels; Long term potentiation; Pb2+

Indexed keywords

CALCIUM ION; LEAD; MALONALDEHYDE; MONOSIALOGANGLIOSIDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; HIPPOCAMPUS; LEAD POISONING; LONG TERM POTENTIATION; MALE; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NEUROTOXICITY; NONHUMAN; RAT;

ANIMALS; CALCIUM; FEMALE; G(M1) GANGLIOSIDE; HIPPOCAMPUS; LEAD POISONING, NERVOUS SYSTEM; LONG-TERM POTENTIATION; MALE; MALONDIALDEHYDE; ORGANOMETALLIC COMPOUNDS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 67349254139     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-008-0379-3     Document Type: Article

References (25)

1. A Bachis SJ Rabin M Del Fiacco I Mocchetti 2002 Gangliosides prevent excitotoxicity through activation of TrkB receptor Neurotox Res 4 3 225 234 (Pubitemid 34679373)
2. BJ Bacskai P Wallen V Lev-Ram S Grillner RY Tsien 1995 Activity-related calcium dynamics in lamprey motoneurons as revealed by video-rate confocal microscopy Neuron 14 1 19 28
3. D Bellinger J Sloman A Leviton M Rabinowitz HL Needleman C Waternaux 1991 Low-level lead exposure and children's cognitive function in the preschool years Pediatrics 87 2 219 227
4. GQ Bi MM Poo 1998 Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type J Neurosci 18 24 10464 10472
5. 3+ J Neurophysiol 71 4 1491 1497 (Pubitemid 24121845)
6. H Esterbauer KH Cheeseman 1990 Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal Methods Enzymol 186 407 421 (Pubitemid 20279982)
7. 2+/calmodulin-dependent protein kinase II by brain gangliosides J Neurochem 54 1 103 109
8. H Furuse H Waki K Kaneko S Fujii M Miura H Sasaki 1998 Effect of the mono- and tetra-sialogangliosides, GM1 and GQ1b, on long-term potentiation in the CA1 hippocampal neurons of the guinea pig Exp Brain Res Experimentelle Hirnforschung 123 3 307 314 (Pubitemid 28526352)
9. ME Gilbert CM Mack SM Lasley 1999 The influence of developmental period of lead exposure on long-term potentiation in the adult rat dentate gyrus in vivo Neurotoxicology 20 1 57 69
10. JM Gutteridge B Halliwell 1990 The measurement and mechanism of lipid peroxidation in biological systems Trends Biochem Sci 15 4 129 135 (Pubitemid 20186835)
11. MT Herrero I Perez-Otano C Oset A Kastner EC Hirsch Y Agid 1993 GM-1 ganglioside promotes the recovery of surviving midbrain dopaminergic neurons in MPTP-treated monkeys Neuroscience 56 4 965 972 (Pubitemid 23308651)
12. JW Lazarewicz E Salinska E Matyja 1995 Ganglioside GM1 prevents N-methyl-D-aspartate neurotoxicity in rabbit hippocampus in vivo. Effects on calcium homeostasis Mol Chem Neuropathol 24 2-3 165 177
13. JR Liu MP Ding EQ Wei JZ Huang Y Song Q Ding 2004 Monosialoganglioside protected ischemic rat hippocampal slices through stabilizing expression of N-methyl-D-aspartate receptor subunit Acta Pharmacologica Sinica 25 6 727 732 (Pubitemid 38736096)
14. T Ma HH Chen IK Ho 1999 Effects of chronic lead (Pb) exposure on neurobehavioral function and dopaminergic neurotransmitter receptors in rats Toxicol Lett 105 2 111 121 (Pubitemid 29132761)
15. J Markovac GW Goldstein 1988 Picomolar concentrations of lead stimulate brain protein kinase C Nature 334 6177 71 73 (Pubitemid 18160554)
16. Y Nagai 1995 Functional roles of gangliosides in bio-signaling Behav Brain Res 66 1-2 99 104
17. B Pei ZP Liu JW Chen 2002 Ganglioside GM(1) biphasically regulates the activity of protein kinase C by the effects on the structure of the lipid bilayer Chem Phys Lipids 114 2 131 138 (Pubitemid 34266987)
18. A Pompella 1997 Biochemistry and histochemistry of oxidant stress and lipid peroxidation Int J Vitam Nutr Res/Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung 67 5 289 297 (Pubitemid 27428691)
19. H Romer H Rahmann 1979 Effects of exogenous neuraminidase on unit activity in frog spinal cord and fish optic tectum Exp Brain Res Experimentelle Hirnforschung 34 1 49 58 (Pubitemid 9212837)
20. DY Ruan JT Chen C Zhao YZ Xu M Wang WF Zhao 1998 Impairment of long-term potentiation and paired-pulse facilitation in rat hippocampal dentate gyrus following developmental lead exposure in vivo Brain Res 806 2 196 201 (Pubitemid 29010494)
21. BA Sabel MD Slavin DG Stein 1984 GM1 ganglioside treatment facilitates behavioral recovery from bilateral brain damage Science (New York, NY) 225 4659 340 342 (Pubitemid 14085981)
22. JQ She M Wang DM Zhu LG Sun DY Ruan 2005 Effect of ganglioside on synaptic plasticity of hippocampus in lead-exposed rats in vivo Brain Res 1060 1-2 162 169 (Pubitemid 41483601)
23. Y Sun LW Oberley Y Li 1988 A simple method for clinical assay of superoxide dismutase Clin Chem 34 3 497 500 (Pubitemid 18102175)
24. XL Tang Y Qiu JF Turrens JZ Sun R Bolli 1997 Late preconditioning against stunning is not mediated by increased antioxidant defenses in conscious pigs Am J Physiol 273 4 Pt 2 H1651 H1657
25. A Wieraszko W Seifert 1984 Evidence for a functional role of gangliosides in synaptic transmission: studies on rat brain striatal slices Neurosci Lett 52 1-2 123 128 (Pubitemid 15179736)