-
2
-
-
84855353573
-
Heart disease and stroke statistics-2012 update: A report from the American Heart Association
-
Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, et al. Heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation 2012;125:e2-220.
-
(2012)
Circulation
, vol.125
, pp. e2-e220
-
-
Roger, V.L.1
Go, A.S.2
Lloyd-Jones, D.M.3
Benjamin, E.J.4
Berry, J.D.5
Borden, W.B.6
-
3
-
-
0027477079
-
Prevalence of aortic valve abnormalities in the elderly: An echocardiographic study of a random population sample
-
Lindroos M, Kupari M, Heikkila J, Tilvis R. Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample. J Am Coll Cardiol 1993;21:1220-5.
-
(1993)
J Am Coll Cardiol
, vol.21
, pp. 1220-1225
-
-
Lindroos, M.1
Kupari, M.2
Heikkila, J.3
Tilvis, R.4
-
5
-
-
77952560272
-
Statins for calcific aortic valve stenosis: Into oblivion after SALTIRE and SEAS? An extensive review from bench to bedside
-
Hermans H, Herijgers P, Holvoet P, Verbeken E, Meuris B, Flameng W, et al. Statins for calcific aortic valve stenosis: into oblivion after SALTIRE and SEAS? An extensive review from bench to bedside. Curr Probl Cardiol 2010;35:284-306.
-
(2010)
Curr Probl Cardiol
, vol.35
, pp. 284-306
-
-
Hermans, H.1
Herijgers, P.2
Holvoet, P.3
Verbeken, E.4
Meuris, B.5
Flameng, W.6
-
7
-
-
0037024284
-
Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve
-
Rajamannan NM, Subramaniam M, Springett M, Sebo TC, Niekrasz M, McConnell JP, et al. Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve. Circulation 2002;105:2660-5.
-
(2002)
Circulation
, vol.105
, pp. 2660-2665
-
-
Rajamannan, N.M.1
Subramaniam, M.2
Springett, M.3
Sebo, T.C.4
Niekrasz, M.5
McConnell, J.P.6
-
8
-
-
50249161499
-
Development of aortic valve sclerosis or stenosis in rabbits: Role of cholesterol and calcium
-
Drolet MC, Couet J, Arsenault M. Development of aortic valve sclerosis or stenosis in rabbits: role of cholesterol and calcium. J Heart Valve Dis 2008;17:381-7.
-
(2008)
J Heart Valve Dis
, vol.17
, pp. 381-387
-
-
Drolet, M.C.1
Couet, J.2
Arsenault, M.3
-
9
-
-
32644445773
-
A high fat/high carbohydrate diet induces aortic valve disease in C57BL/6Jmice
-
Drolet MC, Roussel E, Deshaies Y, Couet J, Arsenault M. A high fat/high carbohydrate diet induces aortic valve disease in C57BL/6Jmice. J Am Coll Cardiol 2006;47:850-5.
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 850-855
-
-
Drolet, M.C.1
Roussel, E.2
Deshaies, Y.3
Couet, J.4
Arsenault, M.5
-
10
-
-
82955247920
-
The LDLR deficient mouse as a model for aortic calcification and quantification by micro-computed tomography
-
Awan Z, Denis M, Bailey D, Giaid A, Prat A, Goltzman D, et al. The LDLR deficient mouse as a model for aortic calcification and quantification by micro-computed tomography. Atherosclerosis 2011;219:455-62.
-
(2011)
Atherosclerosis
, vol.219
, pp. 455-462
-
-
Awan, Z.1
Denis, M.2
Bailey, D.3
Giaid, A.4
Prat, A.5
Goltzman, D.6
-
11
-
-
24644467759
-
Mutations in NOTCH1 cause aortic valve disease
-
Garg V, Muth AN, Ransom JF, Schluterman MK, Barnes R, King IN, et al. Mutations in NOTCH1 cause aortic valve disease. Nature 2005;437:270-4.
-
(2005)
Nature
, vol.437
, pp. 270-274
-
-
Garg, V.1
Muth, A.N.2
Ransom, J.F.3
Schluterman, M.K.4
Barnes, R.5
King, I.N.6
-
12
-
-
0026725757
-
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
-
Plump AS, Smith JD, Hayek T, Aalto-Setala K, Walsh A, Verstuyft JG, et al. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 1992;71:343-53.
-
(1992)
Cell
, vol.71
, pp. 343-353
-
-
Plump, A.S.1
Smith, J.D.2
Hayek, T.3
Aalto-Setala, K.4
Walsh, A.5
Verstuyft, J.G.6
-
14
-
-
84870878926
-
The progression of calcific aortic valve disease through injury, cell dysfunction, and disruptive biologic and physical force feedback loops
-
Li C, Xu S, Gotlieb AI. The progression of calcific aortic valve disease through injury, cell dysfunction, and disruptive biologic and physical force feedback loops. Cardiovasc Pathol 2013;22:1-8.
-
(2013)
Cardiovasc Pathol
, vol.22
, pp. 1-8
-
-
Li, C.1
Xu, S.2
Gotlieb, A.I.3
-
15
-
-
34547564544
-
Molecular and functional characteristics of heart-valve interstitial cells
-
Chester AH, Taylor PM. Molecular and functional characteristics of heart-valve interstitial cells. Philos Trans R Soc Lond B Biol Sci 2007;362:1437-43.
-
(2007)
Philos Trans R Soc Lond B Biol Sci
, vol.362
, pp. 1437-1443
-
-
Chester, A.H.1
Taylor, P.M.2
-
16
-
-
33746560203
-
Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch
-
Ku CH, Johnson PH, Batten P, Sarathchandra P, Chambers RC, Taylor PM, et al. Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch. Cardiovasc Res 2006;71:548-56.
-
(2006)
Cardiovasc Res
, vol.71
, pp. 548-556
-
-
Ku, C.H.1
Johnson, P.H.2
Batten, P.3
Sarathchandra, P.4
Chambers, R.C.5
Taylor, P.M.6
-
17
-
-
84868152490
-
Characterization of porcine aortic valvular interstitial cell 'calcified' nodules
-
Cloyd KL, El-Hamamsy I, Boonrungsiman S, Hedegaard M, Gentleman E, Sarathchandra P, et al. Characterization of porcine aortic valvular interstitial cell 'calcified' nodules. PLoS One 2012;7:e48154.
-
(2012)
PLoS One
, vol.7
, pp. e48154
-
-
Cloyd, K.L.1
El-Hamamsy, I.2
Boonrungsiman, S.3
Hedegaard, M.4
Gentleman, E.5
Sarathchandra, P.6
-
18
-
-
0037314647
-
Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis
-
[discussion 65-6]
-
Jian B, Narula N, Li QY, Mohler ER, Levy RJ. Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis. Ann Thorac Surg 2003;75:457-65 [discussion 65-6].
-
(2003)
Ann Thorac Surg
, vol.75
, pp. 457-465
-
-
Jian, B.1
Narula, N.2
Li, Q.Y.3
Mohler, E.R.4
Levy, R.J.5
-
19
-
-
0038711036
-
Human aortic valve calcification is associated with an osteoblast phenotype
-
Rajamannan NM, Subramaniam M, Rickard D, Stock SR, Donovan J, Springett M, et al. Human aortic valve calcification is associated with an osteoblast phenotype. Circulation 2003;107:2181-4.
-
(2003)
Circulation
, vol.107
, pp. 2181-2184
-
-
Rajamannan, N.M.1
Subramaniam, M.2
Rickard, D.3
Stock, S.R.4
Donovan, J.5
Springett, M.6
-
20
-
-
36749077107
-
Models of aortic valve calcification
-
Guerraty M, Mohler ER. Models of aortic valve calcification. J Investig Med 2007;55:278-83.
-
(2007)
J Investig Med
, vol.55
, pp. 278-283
-
-
Guerraty, M.1
Mohler, E.R.2
-
21
-
-
0035916929
-
Bone formation and inflammation in cardiac valves
-
Mohler ER, Gannon F, Reynolds C, Zimmerman R, Keane MG, Kaplan FS. Bone formation and inflammation in cardiac valves. Circulation 2001;103:1522-8.
-
(2001)
Circulation
, vol.103
, pp. 1522-1528
-
-
Mohler, E.R.1
Gannon, F.2
Reynolds, C.3
Zimmerman, R.4
Keane, M.G.5
Kaplan, F.S.6
-
22
-
-
80052890196
-
Can valvular interstitial cells become true osteoblasts? A side-by-side comparison
-
Monzack EL, Masters KS. Can valvular interstitial cells become true osteoblasts? A side-by-side comparison. J Heart Valve Dis 2011;20:449-63.
-
(2011)
J Heart Valve Dis
, vol.20
, pp. 449-463
-
-
Monzack, E.L.1
Masters, K.S.2
-
24
-
-
85047679915
-
Endothelial cell orientation on aortic valve leaflets
-
Deck JD. Endothelial cell orientation on aortic valve leaflets. Cardiovasc Res 1986;20:760-7.
-
(1986)
Cardiovasc Res
, vol.20
, pp. 760-767
-
-
Deck, J.D.1
-
25
-
-
0023948817
-
Calf Cardiac Valvular Endothelial-Cells in Culture - Production of Glycosaminoglycans, Prostacyclin and Fibronectin
-
Manduteanu I, Popov D, Radu A, Simionescu M. Calf Cardiac Valvular Endothelial-Cells in Culture - Production of Glycosaminoglycans, Prostacyclin and Fibronectin. J Mol Cell Cardiol 1988;20:103-18.
-
(1988)
J Mol Cell Cardiol
, vol.20
, pp. 103-118
-
-
Manduteanu, I.1
Popov, D.2
Radu, A.3
Simionescu, M.4
-
26
-
-
0026629902
-
Nitric-Oxide as a Secretory Product of Mammalian-Cells
-
Nathan C. Nitric-Oxide as a Secretory Product of Mammalian-Cells. FASEB J 1992;6:3051-64.
-
(1992)
FASEB J
, vol.6
, pp. 3051-3064
-
-
Nathan, C.1
-
27
-
-
84868202254
-
Role of Circulating Osteogenic Progenitor Cells in Calcific Aortic Stenosis
-
Gossl M, Khosla S, Zhang X, Higano N, Jordan KL, Loeffler D, et al. Role of Circulating Osteogenic Progenitor Cells in Calcific Aortic Stenosis. J Am Coll Cardiol 2012;60:1945-53.
-
(2012)
J Am Coll Cardiol
, vol.60
, pp. 1945-1953
-
-
Gossl, M.1
Khosla, S.2
Zhang, X.3
Higano, N.4
Jordan, K.L.5
Loeffler, D.6
-
29
-
-
21044437380
-
Spectrum of calcific aortic valve disease - Pathogenesis, disease progression, and treatment strategies
-
Freeman RV, Otto CM. Spectrum of calcific aortic valve disease - Pathogenesis, disease progression, and treatment strategies. Circulation 2005;111:3316-26.
-
(2005)
Circulation
, vol.111
, pp. 3316-3326
-
-
Freeman, R.V.1
Otto, C.M.2
-
30
-
-
84877732914
-
Inflammation Is Associated with the Remodeling of Calcific Aortic Valve Disease
-
Cote N, Mahmut A, Bosse Y, Couture C, Page S, Trahan S, et al. Inflammation Is Associated with the Remodeling of Calcific Aortic Valve Disease. Inflammation 2013;36:573-81.
-
(2013)
Inflammation
, vol.36
, pp. 573-581
-
-
Cote, N.1
Mahmut, A.2
Bosse, Y.3
Couture, C.4
Page, S.5
Trahan, S.6
-
31
-
-
20144377112
-
Inflammatory regulation of extracellular matrix remodeling in calcific aortic valve stenosis
-
Kaden JJ, Demp fle CE, Grobholz R, Fischer CS, Vocke DC, Kilic R, et al. Inflammatory regulation of extracellular matrix remodeling in calcific aortic valve stenosis. Cardiovasc Pathol 2005;14:80-7.
-
(2005)
Cardiovasc Pathol
, vol.14
, pp. 80-87
-
-
Kaden, J.J.1
Demp Fle, C.E.2
Grobholz, R.3
Fischer, C.S.4
Vocke, D.C.5
Kilic, R.6
-
32
-
-
79957674758
-
Molecular Imaging Insights Into Early Inflammatory Stages of Arterial and Aortic Valve Calcification
-
New SEP, Aikawa E. Molecular Imaging Insights Into Early Inflammatory Stages of Arterial and Aortic Valve Calcification. Circ Res 2011;108:1381-91.
-
(2011)
Circ Res
, vol.108
, pp. 1381-1391
-
-
New, S.E.P.1
Aikawa, E.2
-
33
-
-
84874884559
-
Inflammatory Characteristics of Stenotic Aortic Valves: A Comparison between Rheumatic and Nonrheumatic Aortic Stenosis
-
Wallby L, Steffensen T, Jonasson L, Broqvist M. Inflammatory Characteristics of Stenotic Aortic Valves: A Comparison between Rheumatic and Nonrheumatic Aortic Stenosis. Cardiol Res Pract 2013:895215.
-
(2013)
Cardiol Res Pract
, pp. 895215
-
-
Wallby, L.1
Steffensen, T.2
Jonasson, L.3
Broqvist, M.4
-
34
-
-
36348976915
-
The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology
-
Liu AC, Joag VR, Gotlieb AI. The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology. Am J Pathol 2007;171:1407-18.
-
(2007)
Am J Pathol
, vol.171
, pp. 1407-1418
-
-
Liu, A.C.1
Joag, V.R.2
Gotlieb, A.I.3
-
35
-
-
33749676226
-
Human pulmonary valve progenitor cells exhibit endothelial/mesenchymal plasticity in response to vascular endothelial growth factor-A and transforming growth factor-beta2
-
Paruchuri S, Yang JH, Aikawa E, Melero-Martin JM, Khan ZA, Loukogeorgakis S, et al. Human pulmonary valve progenitor cells exhibit endothelial/mesenchymal plasticity in response to vascular endothelial growth factor-A and transforming growth factor-beta2. Circ Res 2006;99:861-9.
-
(2006)
Circ Res
, vol.99
, pp. 861-869
-
-
Paruchuri, S.1
Yang, J.H.2
Aikawa, E.3
Melero-Martin, J.M.4
Khan, Z.A.5
Loukogeorgakis, S.6
-
36
-
-
84055179016
-
Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve
-
Balachandran K, Alford PW, Wylie-Sears J, Goss JA, Grosberg A, Bischoff J, et al. Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve. Proc Natl Acad Sci U S A 2011;108:19943-8.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 19943-19948
-
-
Balachandran, K.1
Alford, P.W.2
Wylie-Sears, J.3
Goss, J.A.4
Grosberg, A.5
Bischoff, J.6
-
37
-
-
84894988652
-
Myocardial contraction and hyaluronic acidmechanotransduction in epithelial-to-mesenchymal transformation of endocardial cells
-
Sewell-Loftin MK, DeLaughter DM, Peacock JR, Brown CB, Baldwin HS, Barnett JV, et al. Myocardial contraction and hyaluronic acidmechanotransduction in epithelial-to-mesenchymal transformation of endocardial cells. Biomaterials 2014;35:2809-15.
-
(2014)
Biomaterials
, vol.35
, pp. 2809-2815
-
-
Sewell-Loftin, M.K.1
DeLaughter, D.M.2
Peacock, J.R.3
Brown, C.B.4
Baldwin, H.S.5
Barnett, J.V.6
-
38
-
-
0033057678
-
Identification and characterization of calcifying valve cells from human and canine aortic valves
-
Mohler ER, Chawla MK, Chang AW, Vyavahare N, Levy RJ, Graham L, et al. Identification and characterization of calcifying valve cells from human and canine aortic valves. J Heart Valve Dis 1999;8:254-60.
-
(1999)
J Heart Valve Dis
, vol.8
, pp. 254-260
-
-
Mohler, E.R.1
Chawla, M.K.2
Chang, A.W.3
Vyavahare, N.4
Levy, R.J.5
Graham, L.6
-
39
-
-
7044260650
-
Expression of bone sialoprotein and bone morphogenetic protein-2 in calcific aortic stenosis
-
Kaden JJ, Bickelhaupt S, Grobholz R, Vahl CF, Hagl S, Brueckmann M, et al. Expression of bone sialoprotein and bone morphogenetic protein-2 in calcific aortic stenosis. J Heart Valve Dis 2004;13:560-6.
-
(2004)
J Heart Valve Dis
, vol.13
, pp. 560-566
-
-
Kaden, J.J.1
Bickelhaupt, S.2
Grobholz, R.3
Vahl, C.F.4
Hagl, S.5
Brueckmann, M.6
-
40
-
-
0242664267
-
Msx2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors
-
Cheng SL, Shao JS, Charlton-Kachigian N, Loewy AP, Towler DA. Msx2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors. J Biol Chem 2003;278:45969-77.
-
(2003)
J Biol Chem
, vol.278
, pp. 45969-45977
-
-
Cheng, S.L.1
Shao, J.S.2
Charlton-Kachigian, N.3
Loewy, A.P.4
Towler, D.A.5
-
41
-
-
70349135494
-
Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: Role of Smad1 and extracellular signal-regulated kinase 1/2
-
Yang XP, Meng XZ, Su X, Mauchley DC, Ao LH, Cleveland JC, et al. Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: Role of Smad1 and extracellular signal-regulated kinase 1/2. J Thorac Cardiovasc Surg 2009;138:1008-15.
-
(2009)
J Thorac Cardiovasc Surg
, vol.138
, pp. 1008-1015
-
-
Yang, X.P.1
Meng, X.Z.2
Su, X.3
Mauchley, D.C.4
Ao, L.H.5
Cleveland, J.C.6
-
42
-
-
33646564670
-
Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: Effects of steady shear stress
-
Butcher JT, Nerem RM. Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress. Tissue Eng 2006;12:905-15.
-
(2006)
Tissue Eng
, vol.12
, pp. 905-915
-
-
Butcher, J.T.1
Nerem, R.M.2
-
43
-
-
84876562106
-
Sidespecific endothelial-dependent regulation of aortic valve calcification: Interplay of hemodynamics and nitric oxide signaling
-
Richards J, El-Hamamsy I, Chen S, Sarang Z, Sarathchandra P, Yacoub MH, et al. Sidespecific endothelial-dependent regulation of aortic valve calcification: interplay of hemodynamics and nitric oxide signaling. Am J Pathol 2013;182:1922-31.
-
(2013)
Am J Pathol
, vol.182
, pp. 1922-1931
-
-
Richards, J.1
El-Hamamsy, I.2
Chen, S.3
Sarang, Z.4
Sarathchandra, P.5
Yacoub, M.H.6
-
44
-
-
84888606219
-
A three-dimensional co-culture model of the aortic valve using magnetic levitation
-
Tseng H, Balaoing LR, Grigoryan B, Raphael RM, Killian TC, Souza GR, et al. A three-dimensional co-culture model of the aortic valve using magnetic levitation. Acta Biomater 2014;10:173-82.
-
(2014)
Acta Biomater
, vol.10
, pp. 173-182
-
-
Tseng, H.1
Balaoing, L.R.2
Grigoryan, B.3
Raphael, R.M.4
Killian, T.C.5
Souza, G.R.6
-
45
-
-
0034681453
-
Oxidized low density lipoproteins regulate synthesis of monkey aortic smooth muscle cell proteoglycans that have enhanced native low density lipoprotein binding properties
-
Chang MY, Potter-Perigo S, Tsoi C, Chait A, Wight TN. Oxidized low density lipoproteins regulate synthesis of monkey aortic smooth muscle cell proteoglycans that have enhanced native low density lipoprotein binding properties. J Biol Chem 2000;275:4766-73.
-
(2000)
J Biol Chem
, vol.275
, pp. 4766-4773
-
-
Chang, M.Y.1
Potter-Perigo, S.2
Tsoi, C.3
Chait, A.4
Wight, T.N.5
-
46
-
-
84857662538
-
Swine as models in biomedical research and toxicology testing
-
Swindle MM, Makin A, Herron AJ, Clubb FJ, Frazier KS. Swine as models in biomedical research and toxicology testing. Vet Pathol 2012;49:344-56.
-
(2012)
Vet Pathol
, vol.49
, pp. 344-356
-
-
Swindle, M.M.1
Makin, A.2
Herron, A.J.3
Clubb, F.J.4
Frazier, K.S.5
-
47
-
-
0032127268
-
The atherosclerotic Yucatan animal model to study the arterial response after balloon angioplasty: The natural history of remodeling
-
de Smet BJ, van der Zande J, van der Helm YJ, Kuntz RE, Borst C, Post MJ. The atherosclerotic Yucatan animal model to study the arterial response after balloon angioplasty: the natural history of remodeling. Cardiovasc Res 1998;39:224-32.
-
(1998)
Cardiovasc Res
, vol.39
, pp. 224-232
-
-
De Smet, B.J.1
Van Der Zande, J.2
Van Der Helm, Y.J.3
Kuntz, R.E.4
Borst, C.5
Post, M.J.6
-
48
-
-
17644380642
-
Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves
-
Simmons CA, Grant GR, Manduchi E, Davies PF. Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves. Circ Res 2005;96:792-9.
-
(2005)
Circ Res
, vol.96
, pp. 792-799
-
-
Simmons, C.A.1
Grant, G.R.2
Manduchi, E.3
Davies, P.F.4
-
49
-
-
0023463272
-
Porcine cardiac valvular subendothelial cells in culture: Cell isolation and growth characteristics
-
Johnson CM, Hanson MN, Helgeson SC. Porcine cardiac valvular subendothelial cells in culture: cell isolation and growth characteristics. J Mol Cell Cardiol 1987;19:1185-93.
-
(1987)
J Mol Cell Cardiol
, vol.19
, pp. 1185-1193
-
-
Johnson, C.M.1
Hanson, M.N.2
Helgeson, S.C.3
-
50
-
-
0029872448
-
Cell biology of valvular interstitial cells
-
Mulholland DL, Gotlieb AI. Cell biology of valvular interstitial cells. Can J Cardiol 1996;12:231-6.
-
(1996)
Can J Cardiol
, vol.12
, pp. 231-236
-
-
Mulholland, D.L.1
Gotlieb, A.I.2
-
51
-
-
70449706072
-
Factors influencing the oxygen consumption rate of aortic valve interstitial cells: Application to tissue engineering
-
Wang L, Wilshaw SP, Korossis S, Fisher J, Jin Z, Ingham E. Factors influencing the oxygen consumption rate of aortic valve interstitial cells: application to tissue engineering. Tissue Eng Part C Methods 2009;15:355-63.
-
(2009)
Tissue Eng Part C Methods
, vol.15
, pp. 355-363
-
-
Wang, L.1
Wilshaw, S.P.2
Korossis, S.3
Fisher, J.4
Jin, Z.5
Ingham, E.6
-
52
-
-
28944438309
-
Activation of valvular interstitial cells is mediated by transforming growth factor-beta 1 interactions with matrix molecules
-
Cushing MC, Liao JT, Anseth KS. Activation of valvular interstitial cells is mediated by transforming growth factor-beta 1 interactions with matrix molecules. Matrix Biol 2005;24:428-37.
-
(2005)
Matrix Biol
, vol.24
, pp. 428-437
-
-
Cushing, M.C.1
Liao, J.T.2
Anseth, K.S.3
-
53
-
-
41749083044
-
Cofilin is a marker of myofibroblast differentiation in cells from porcine aortic cardiac valves
-
Pho M, Lee W, Watt DR, Laschinger C, Simmons CA, McCulloch CA. Cofilin is a marker of myofibroblast differentiation in cells from porcine aortic cardiac valves. Am J Physiol Heart Circ Physiol 2008;294:H1767-78.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
, pp. H1767-H1778
-
-
Pho, M.1
Lee, W.2
Watt, D.R.3
Laschinger, C.4
Simmons, C.A.5
McCulloch, C.A.6
-
54
-
-
33847293734
-
Transforming growth factor-beta1 mechanisms in aortic valve calcification: Increased alkaline phosphatase and related events
-
Clark-Greuel JN, Connolly JM, Sorichillo E, Narula NR, Rapoport HS, Mohler ER, et al. Transforming growth factor-beta1 mechanisms in aortic valve calcification: increased alkaline phosphatase and related events. Ann Thorac Surg 2007;83:946-53.
-
(2007)
Ann Thorac Surg
, vol.83
, pp. 946-953
-
-
Clark-Greuel, J.N.1
Connolly, J.M.2
Sorichillo, E.3
Narula, N.R.4
Rapoport, H.S.5
Mohler, E.R.6
-
56
-
-
84858447975
-
Pathology, protein expression and signaling in myxomatous mitral valve degeneration: Comparison of dogs and humans
-
Aupperle H, Disatian S. Pathology, protein expression and signaling in myxomatous mitral valve degeneration: comparison of dogs and humans. J Vet Cardiol 2012;14:59-71.
-
(2012)
J Vet Cardiol
, vol.14
, pp. 59-71
-
-
Aupperle, H.1
Disatian, S.2
-
57
-
-
0842305028
-
Mechanism of dystrophic calcification in rabbit aortas: Temporal and spatial distributions of calcifying vesicles and calcification-related structural proteins
-
Hsu HH, Tawfik O, Sun F. Mechanism of dystrophic calcification in rabbit aortas: temporal and spatial distributions of calcifying vesicles and calcification-related structural proteins. Cardiovasc Pathol 2004;13:3-10.
-
(2004)
Cardiovasc Pathol
, vol.13
, pp. 3-10
-
-
Hsu, H.H.1
Tawfik, O.2
Sun, F.3
-
58
-
-
0035005753
-
Experimental hypercholesterolemia induces apoptosis in the aortic valve
-
Rajamannan NM, Sangiorgi G, Springett M, Arnold K, Mohacsi T, Spagnoli LG, et al. Experimental hypercholesterolemia induces apoptosis in the aortic valve. J Heart Valve Dis 2001;10:371-4.
-
(2001)
J Heart Valve Dis
, vol.10
, pp. 371-374
-
-
Rajamannan, N.M.1
Sangiorgi, G.2
Springett, M.3
Arnold, K.4
Mohacsi, T.5
Spagnoli, L.G.6
-
59
-
-
0036185431
-
Induction of calcification in rabbit aortas by high cholesterol diets: Roles of calcifiable vesicles in dystrophic calcification
-
Hsu HH, Camacho NC, Tawfik O, Sun F. Induction of calcification in rabbit aortas by high cholesterol diets: roles of calcifiable vesicles in dystrophic calcification. Atherosclerosis 2002;161:85-94.
-
(2002)
Atherosclerosis
, vol.161
, pp. 85-94
-
-
Hsu, H.H.1
Camacho, N.C.2
Tawfik, O.3
Sun, F.4
-
60
-
-
0028216808
-
Notch1 is essential for postimplantation development in mice
-
Swiatek PJ, Lindsell CE, del Amo FF, Weinmaster G, Gridley T. Notch1 is essential for postimplantation development in mice. Genes Dev 1994;8:707-19.
-
(1994)
Genes Dev
, vol.8
, pp. 707-719
-
-
Swiatek, P.J.1
Lindsell, C.E.2
Del Amo, F.F.3
Weinmaster, G.4
Gridley, T.5
-
61
-
-
79959714407
-
Diet-induced aortic valve disease in mice haploinsufficient for the Notch pathway effector RBPJK/CSL
-
Nus M, MacGrogan D, Martinez-Poveda B, Benito Y, Casanova JC, Fernandez-Aviles F, et al. Diet-induced aortic valve disease in mice haploinsufficient for the Notch pathway effector RBPJK/CSL. Arterioscler Thromb Vasc Biol 2011;31:1580-8.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 1580-1588
-
-
Nus, M.1
MacGrogan, D.2
Martinez-Poveda, B.3
Benito, Y.4
Casanova, J.C.5
Fernandez-Aviles, F.6
-
62
-
-
77955943689
-
Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: A role for inflammation
-
Hjortnaes J, Butcher J, Figueiredo JL, Riccio M, Kohler RH, Kozloff KM, et al. Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation. Eur Heart J 2010;31:1975-84.
-
(2010)
Eur Heart J
, vol.31
, pp. 1975-1984
-
-
Hjortnaes, J.1
Butcher, J.2
Figueiredo, J.L.3
Riccio, M.4
Kohler, R.H.5
Kozloff, K.M.6
-
63
-
-
0027958084
-
ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree
-
Nakashima Y, Plump AS, Raines EW, Breslow JL, Ross R. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb 1994;14:133-40.
-
(1994)
Arterioscler Thromb
, vol.14
, pp. 133-140
-
-
Nakashima, Y.1
Plump, A.S.2
Raines, E.W.3
Breslow, J.L.4
Ross, R.5
-
64
-
-
0032516054
-
Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: No accentuation by apolipoprotein(a)
-
Sanan DA, Newland DL, Tao R, Marcovina S, Wang J, Mooser V, et al. Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a). Proc Natl Acad Sci U S A 1998;95:4544-9.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 4544-4549
-
-
Sanan, D.A.1
Newland, D.L.2
Tao, R.3
Marcovina, S.4
Wang, J.5
Mooser, V.6
-
66
-
-
33645739512
-
Human semilunar cardiac valve remodeling by activated cells from fetus to adult: Implications for postnatal adaptation, pathology, and tissue engineering
-
Aikawa E, Whittaker P, Farber M, Mendelson K, Padera RF, Aikawa M, et al. Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. Circulation 2006;113:1344-52.
-
(2006)
Circulation
, vol.113
, pp. 1344-1352
-
-
Aikawa, E.1
Whittaker, P.2
Farber, M.3
Mendelson, K.4
Padera, R.F.5
Aikawa, M.6
-
67
-
-
79958828890
-
Cell-matrix interactions in the pathobiology of calcific aortic valve disease: Critical roles for matricellular, matricrine, and matrix mechanics cues
-
Chen JH, Simmons CA. Cell-matrix interactions in the pathobiology of calcific aortic valve disease: critical roles for matricellular, matricrine, and matrix mechanics cues. Circ Res 2011;108:1510-24.
-
(2011)
Circ Res
, vol.108
, pp. 1510-1524
-
-
Chen, J.H.1
Simmons, C.A.2
-
68
-
-
64049113676
-
Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix
-
Yip CY, Chen JH, Zhao R, Simmons CA. Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix. Arterioscler Thromb Vasc Biol 2009;29:936-42.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 936-942
-
-
Yip, C.Y.1
Chen, J.H.2
Zhao, R.3
Simmons, C.A.4
-
69
-
-
77951610270
-
Regulation of valvular interstitial cell calcification by adhesive peptide sequences
-
Gu X, Masters KS. Regulation of valvular interstitial cell calcification by adhesive peptide sequences. J Biomed Mater Res A 2010;93:1620-30.
-
(2010)
J Biomed Mater Res A
, vol.93
, pp. 1620-1630
-
-
Gu, X.1
Masters, K.S.2
-
70
-
-
59649120970
-
Substrate properties influence calcification in valvular interstitial cell culture
-
Benton JA, Kern HB, Anseth KS. Substrate properties influence calcification in valvular interstitial cell culture. J Heart Valve Dis 2008;17:689-99.
-
(2008)
J Heart Valve Dis
, vol.17
, pp. 689-699
-
-
Benton, J.A.1
Kern, H.B.2
Anseth, K.S.3
-
71
-
-
0037213852
-
Three-dimensional tissue structure affects sensitivity of fibroblasts to TGF-beta 1
-
Kunz-Schughart LA, Wenninger S, Neumeier T, Seidl P, Knuechel R. Three-dimensional tissue structure affects sensitivity of fibroblasts to TGF-beta 1. Am J Physiol Cell Physiol 2003;284:C209-19.
-
(2003)
Am J Physiol Cell Physiol
, vol.284
, pp. C209-C219
-
-
Kunz-Schughart, L.A.1
Wenninger, S.2
Neumeier, T.3
Seidl, P.4
Knuechel, R.5
-
72
-
-
5144233686
-
Porcine aortic valve interstitial cells in three-dimensional culture: Comparison of phenotype with aortic smooth muscle cells
-
Butcher JT, Nerem RM. Porcine aortic valve interstitial cells in three-dimensional culture: Comparison of phenotype with aortic smooth muscle cells. J Heart Valve Dis 2004;13:478-85.
-
(2004)
J Heart Valve Dis
, vol.13
, pp. 478-485
-
-
Butcher, J.T.1
Nerem, R.M.2
-
73
-
-
0026575408
-
Micromechanics of the fibrosa and the ventricularis in aortic valve leaflets
-
Vesely I, Noseworthy R. Micromechanics of the fibrosa and the ventricularis in aortic valve leaflets. J Biomech 1992;25:101-13.
-
(1992)
J Biomech
, vol.25
, pp. 101-113
-
-
Vesely, I.1
Noseworthy, R.2
-
74
-
-
84867185117
-
A novel technique for quantifying mouse heart valve leaflet stiffness with atomic force microscopy
-
Sewell-Loftin MK, Brown CB, Baldwin HS, Merryman WD. A novel technique for quantifying mouse heart valve leaflet stiffness with atomic force microscopy. J Heart Valve Dis 2012;21:513-20.
-
(2012)
J Heart Valve Dis
, vol.21
, pp. 513-520
-
-
Sewell-Loftin, M.K.1
Brown, C.B.2
Baldwin, H.S.3
Merryman, W.D.4
-
75
-
-
27744572738
-
The effects of cellular contraction on aortic valve leaflet flexural stiffness
-
Merryman WD, Huang HY, Schoen FJ, Sacks MS. The effects of cellular contraction on aortic valve leaflet flexural stiffness. J Biomech 2006;39:88-96.
-
(2006)
J Biomech
, vol.39
, pp. 88-96
-
-
Merryman, W.D.1
Huang, H.Y.2
Schoen, F.J.3
Sacks, M.S.4
-
76
-
-
78049440523
-
Microstructural and biomechanical alterations of the human aorta as a function of age and location
-
Haskett D, Johnson G, Zhou A, Utzinger U, Vande Geest J. Microstructural and biomechanical alterations of the human aorta as a function of age and location. Biomech Model Mechanobiol 2010;9:725-36.
-
(2010)
Biomech Model Mechanobiol
, vol.9
, pp. 725-736
-
-
Haskett, D.1
Johnson, G.2
Zhou, A.3
Utzinger, U.4
Vande Geest, J.5
-
77
-
-
72149090648
-
Mechano-potential etiologies of aortic valve disease
-
Merryman WD. Mechano-potential etiologies of aortic valve disease. J Biomech 2010;43:87-92.
-
(2010)
J Biomech
, vol.43
, pp. 87-92
-
-
Merryman, W.D.1
-
78
-
-
64749086542
-
Aortic valve calcification: Basic science to clinical practice
-
Akat K, Borggrefe M, Kaden JJ. Aortic valve calcification: basic science to clinical practice. Heart 2009;95:616-23.
-
(2009)
Heart
, vol.95
, pp. 616-623
-
-
Akat, K.1
Borggrefe, M.2
Kaden, J.J.3
-
79
-
-
0037417964
-
Flow, NO, and atherogenesis
-
Cooke JP. Flow, NO, and atherogenesis. Proc Natl Acad Sci U S A 2003;100:768-70.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 768-770
-
-
Cooke, J.P.1
-
80
-
-
27844457560
-
Interstitial fluid flow induces myofibroblast differentiation and collagen alignment in vitro
-
Ng CP, Hinz B, Swartz MA. Interstitial fluid flow induces myofibroblast differentiation and collagen alignment in vitro. J Cell Sci 2005;118:4731-9.
-
(2005)
J Cell Sci
, vol.118
, pp. 4731-4739
-
-
Ng, C.P.1
Hinz, B.2
Swartz, M.A.3
-
81
-
-
84871762585
-
Calcific nodule morphogenesis by heart valve interstitial cells is strain dependent
-
Fisher CI, Chen J, Merryman WD. Calcific nodule morphogenesis by heart valve interstitial cells is strain dependent. Biomech Model Mechanobiol 2013;12:5-17.
-
(2013)
Biomech Model Mechanobiol
, vol.12
, pp. 5-17
-
-
Fisher, C.I.1
Chen, J.2
Merryman, W.D.3
-
82
-
-
77954568359
-
Elevated cyclic stretch induces aortic valve calcification in a bone morphogenic protein-dependent manner
-
Balachandran K, Sucosky P, Jo H, Yoganathan AP. Elevated cyclic stretch induces aortic valve calcification in a bone morphogenic protein-dependent manner. Am J Pathol 2010;177:49-57.
-
(2010)
Am J Pathol
, vol.177
, pp. 49-57
-
-
Balachandran, K.1
Sucosky, P.2
Jo, H.3
Yoganathan, A.P.4
-
83
-
-
4344715209
-
Mechanical stimulation and mitogen-activated protein kinase signaling independently regulate osteogenic differentiation and mineralization by calcifying vascular cells
-
Simmons CA, Nikolovski J, Thornton AJ, Matlis S, Mooney DJ. Mechanical stimulation and mitogen-activated protein kinase signaling independently regulate osteogenic differentiation and mineralization by calcifying vascular cells. J Biomech 2004;37:1531-41.
-
(2004)
J Biomech
, vol.37
, pp. 1531-1541
-
-
Simmons, C.A.1
Nikolovski, J.2
Thornton, A.J.3
Matlis, S.4
Mooney, D.J.5
-
84
-
-
34548485827
-
Synergistic effects of cyclic tension and transforming growth factor-beta1 on the aortic valve myofibroblast
-
Merryman WD, Lukoff HD, Long RA, Engelmayr GC, Hopkins RA, Sacks MS. Synergistic effects of cyclic tension and transforming growth factor-beta1 on the aortic valve myofibroblast. Cardiovasc Pathol 2007;16:268-76.
-
(2007)
Cardiovasc Pathol
, vol.16
, pp. 268-276
-
-
Merryman, W.D.1
Lukoff, H.D.2
Long, R.A.3
Engelmayr, G.C.4
Hopkins, R.A.5
Sacks, M.S.6
-
85
-
-
4043127381
-
Valvular myofibroblast activation by transforming growth factor-beta: Implications for pathological extracellular matrix remodeling in heart valve disease
-
Walker GA, Masters KS, Shah DN, Anseth KS, Leinwand LA. Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res 2004;95:253-60.
-
(2004)
Circ Res
, vol.95
, pp. 253-260
-
-
Walker, G.A.1
Masters, K.S.2
Shah, D.N.3
Anseth, K.S.4
Leinwand, L.A.5
-
86
-
-
84867398372
-
5-HT(2B) antagonism arrests non-canonical TGF-beta1-induced valvular myofibroblast differentiation
-
Hutcheson JD, Ryzhova LM, Setola V, Merryman WD. 5-HT(2B) antagonism arrests non-canonical TGF-beta1-induced valvular myofibroblast differentiation. J Mol Cell Cardiol 2012;53:707-14.
-
(2012)
J Mol Cell Cardiol
, vol.53
, pp. 707-714
-
-
Hutcheson, J.D.1
Ryzhova, L.M.2
Setola, V.3
Merryman, W.D.4
-
87
-
-
37249044357
-
Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix
-
Wipff PJ, Rifkin DB, Meister JJ, Hinz B. Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix. J Cell Biol 2007;179:1311-23.
-
(2007)
J Cell Biol
, vol.179
, pp. 1311-1323
-
-
Wipff, P.J.1
Rifkin, D.B.2
Meister, J.J.3
Hinz, B.4
-
88
-
-
44949107350
-
Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells
-
Cushing MC, Mariner PD, Liao JT, Sims EA, Anseth KS. Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells. FASEB J 2008;22:1769-77.
-
(2008)
FASEB J
, vol.22
, pp. 1769-1777
-
-
Cushing, M.C.1
Mariner, P.D.2
Liao, J.T.3
Sims, E.A.4
Anseth, K.S.5
-
89
-
-
84871778802
-
Cadherin-11 regulates cell-cell tension necessary for calcific nodule formation by valvular myofibroblasts
-
Hutcheson JD, Chen J, Sewell-Loftin MK, Ryzhova LM, Fisher CI, Su YR, et al. Cadherin-11 regulates cell-cell tension necessary for calcific nodule formation by valvular myofibroblasts. Arterioscler Thromb Vasc Biol 2013;33:114-20.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 114-120
-
-
Hutcheson, J.D.1
Chen, J.2
Sewell-Loftin, M.K.3
Ryzhova, L.M.4
Fisher, C.I.5
Su, Y.R.6
-
90
-
-
84880517293
-
Molecular and cellular aspects of calcific aortic valve disease
-
Towler DA. Molecular and cellular aspects of calcific aortic valve disease. Circ Res 2013;113:198-208.
-
(2013)
Circ Res
, vol.113
, pp. 198-208
-
-
Towler, D.A.1
-
91
-
-
77949388887
-
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
-
Peacock JD, Levay AK, Gillaspie DB, Tao G, Lincoln J. Reduced sox9 function promotes heart valve calcification phenotypes in vivo. Circ Res 2010;106:712-9.
-
(2010)
Circ Res
, vol.106
, pp. 712-719
-
-
Peacock, J.D.1
Levay, A.K.2
Gillaspie, D.B.3
Tao, G.4
Lincoln, J.5
-
92
-
-
18244390222
-
Msx2 promotes cardiovascular calcification by activating paracrine Wnt signals
-
Shao JS, Cheng SL, Pingsterhaus JM, Charlton-Kachigian N, Loewy AP, Towler DA. Msx2 promotes cardiovascular calcification by activating paracrine Wnt signals. J Clin Invest 2005;115:1210-20.
-
(2005)
J Clin Invest
, vol.115
, pp. 1210-1220
-
-
Shao, J.S.1
Cheng, S.L.2
Pingsterhaus, J.M.3
Charlton-Kachigian, N.4
Loewy, A.P.5
Towler, D.A.6
-
93
-
-
80052890627
-
Inhibition of pathological differentiation of valvular interstitial cells by C-type natriuretic peptide
-
Yip CY, Blaser MC, Mirzaei Z, Zhong X, Simmons CA. Inhibition of pathological differentiation of valvular interstitial cells by C-type natriuretic peptide. Arterioscler Thromb Vasc Biol 2011;31:1881-9.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 1881-1889
-
-
Yip, C.Y.1
Blaser, M.C.2
Mirzaei, Z.3
Zhong, X.4
Simmons, C.A.5
-
94
-
-
24644510707
-
Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp5 receptor pathway
-
Rajamannan NM, Subramaniam M, Caira F, Stock SR, Spelsberg TC. Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp5 receptor pathway. Circulation 2005;112:I229-34.
-
(2005)
Circulation
, vol.112
, pp. I229-I234
-
-
Rajamannan, N.M.1
Subramaniam, M.2
Caira, F.3
Stock, S.R.4
Spelsberg, T.C.5
-
95
-
-
84872953219
-
Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis
-
Branchetti E, Sainger R, Poggio P, Grau JB, Patterson-Fortin J, Bavaria JE, et al. Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis. Arterioscler Thromb Vasc Biol 2013;33:e66-74.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. e66-e74
-
-
Branchetti, E.1
Sainger, R.2
Poggio, P.3
Grau, J.B.4
Patterson-Fortin, J.5
Bavaria, J.E.6
-
96
-
-
49849089138
-
Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans
-
Miller JD, Chu Y, Brooks RM, Richenbacher WE, Pena-Silva R, Heistad DD. Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans. J Am Coll Cardiol 2008;52:843-50.
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 843-850
-
-
Miller, J.D.1
Chu, Y.2
Brooks, R.M.3
Richenbacher, W.E.4
Pena-Silva, R.5
Heistad, D.D.6
-
97
-
-
79251474710
-
Inhibition of Notch1 signaling by Runx2 during osteoblast differentiation
-
Ann EJ, Kim HY, Choi YH, Kim MY, Mo JS, Jung J, et al. Inhibition of Notch1 signaling by Runx2 during osteoblast differentiation. J Bone Miner Res 2011;26:317-30.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 317-330
-
-
Ann, E.J.1
Kim, H.Y.2
Choi, Y.H.3
Kim, M.Y.4
Mo, J.S.5
Jung, J.6
-
98
-
-
81155128090
-
Inhibitory role of Notch1 in calcific aortic valve disease
-
Acharya A, Hans CP, Koenig SN, Nichols HA, Galindo CL, Garner HR, et al. Inhibitory role of Notch1 in calcific aortic valve disease. PLoS One 2011;6:e27743.
-
(2011)
PLoS One
, vol.6
, pp. e27743
-
-
Acharya, A.1
Hans, C.P.2
Koenig, S.N.3
Nichols, H.A.4
Galindo, C.L.5
Garner, H.R.6
-
99
-
-
40749104256
-
Oxidant generation predominates around calcifying foci and enhances progression of aortic valve calcification
-
Liberman M, Bassi E, Martinatti MK, Lario FC, Wosniak J, Pomerantzeff PM, et al. Oxidant generation predominates around calcifying foci and enhances progression of aortic valve calcification. Arterioscler Thromb Vasc Biol 2008;28:463-70.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 463-470
-
-
Liberman, M.1
Bassi, E.2
Martinatti, M.K.3
Lario, F.C.4
Wosniak, J.5
Pomerantzeff, P.M.6
-
100
-
-
84887922423
-
Effects of dexamethasone, ascorbic acid and beta-glycerophosphate on the osteogenic differentiation of stem cells in vitro
-
Langenbach F, Handschel J. Effects of dexamethasone, ascorbic acid and beta-glycerophosphate on the osteogenic differentiation of stem cells in vitro. Stem Cell Res Ther 2013;4:117.
-
(2013)
Stem Cell Res Ther
, vol.4
, pp. 117
-
-
Langenbach, F.1
Handschel, J.2
-
101
-
-
0024397110
-
In vitro mineralization of fetal rat parietal bones in defined serum-free medium: Effect of beta-glycerol phosphate
-
Gronowicz G, Woodiel FN, McCarthy MB, Raisz LG. In vitro mineralization of fetal rat parietal bones in defined serum-free medium: effect of beta-glycerol phosphate. J Bone Miner Res 1989;4:313-24.
-
(1989)
J Bone Miner Res
, vol.4
, pp. 313-324
-
-
Gronowicz, G.1
Woodiel, F.N.2
McCarthy, M.B.3
Raisz, L.G.4
-
102
-
-
79953012725
-
Tumor necrosis factor-alpha accelerates the calcification of human aortic valve interstitial cells obtained from patients with calcific aortic valve stenosis via the BMP2-Dlx5 pathway
-
Yu Z, Seya K, Daitoku K, Motomura S, Fukuda I, Furukawa K. Tumor necrosis factor-alpha accelerates the calcification of human aortic valve interstitial cells obtained from patients with calcific aortic valve stenosis via the BMP2-Dlx5 pathway. J Pharmacol Exp Ther 2011;337:16-23.
-
(2011)
J Pharmacol Exp Ther
, vol.337
, pp. 16-23
-
-
Yu, Z.1
Seya, K.2
Daitoku, K.3
Motomura, S.4
Fukuda, I.5
Furukawa, K.6
-
103
-
-
36348963624
-
Aortic Msx2-Wnt calcification cascade is regulated by TNF-alpha-dependent signals in diabetic Ldlr-/-mice
-
Al-Aly Z, Shao JS, Lai CF, Huang E, Cai J, Behrmann A, et al. Aortic Msx2-Wnt calcification cascade is regulated by TNF-alpha-dependent signals in diabetic Ldlr-/-mice. Arterioscler Thromb Vasc Biol 2007;27:2589-96.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 2589-2596
-
-
Al-Aly, Z.1
Shao, J.S.2
Lai, C.F.3
Huang, E.4
Cai, J.5
Behrmann, A.6
-
104
-
-
54749138371
-
Notch signaling in cardiovascular disease and calcification
-
Rusanescu G, Weissleder R, Aikawa E. Notch signaling in cardiovascular disease and calcification. Curr Cardiol Rev 2008;4:148-56.
-
(2008)
Curr Cardiol Rev
, vol.4
, pp. 148-156
-
-
Rusanescu, G.1
Weissleder, R.2
Aikawa, E.3
-
105
-
-
84866466714
-
Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves
-
Zeng Q, Jin C, Ao L, Cleveland JC, Song R, Xu D, et al. Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves. Circulation 2012;126:S222-30.
-
(2012)
Circulation
, vol.126
, pp. S222-S230
-
-
Zeng, Q.1
Jin, C.2
Ao, L.3
Cleveland, J.C.4
Song, R.5
Xu, D.6
-
106
-
-
58949103283
-
Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2
-
Yang X, Fullerton DA, Su X, Ao L, Cleveland JC, Meng X. Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2. J Am Coll Cardiol 2009;53:491-500.
-
(2009)
J Am Coll Cardiol
, vol.53
, pp. 491-500
-
-
Yang, X.1
Fullerton, D.A.2
Su, X.3
Ao, L.4
Cleveland, J.C.5
Meng, X.6
-
107
-
-
33746860419
-
Pathogenesis of calcific aortic valve disease: A disease process comes of age (and a good deal more)
-
O'Brien KD. Pathogenesis of calcific aortic valve disease: a disease process comes of age (and a good deal more). Arterioscler Thromb Vasc Biol 2006;26:1721-8.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1721-1728
-
-
O'Brien, K.D.1
-
108
-
-
0347004546
-
Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulate aortic valve calcification
-
Kaden JJ, Bickelhaupt S, Grobholz R, Haase KK, Sarikoc A, Kilic R, et al. Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulate aortic valve calcification. J Mol Cell Cardiol 2004;36:57-66.
-
(2004)
J Mol Cell Cardiol
, vol.36
, pp. 57-66
-
-
Kaden, J.J.1
Bickelhaupt, S.2
Grobholz, R.3
Haase, K.K.4
Sarikoc, A.5
Kilic, R.6
-
109
-
-
21044441395
-
Distinct effects of PPARgamma insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells
-
Kawaguchi H, Akune T, Yamaguchi M, Ohba S, Ogata N, Chung UI, et al. Distinct effects of PPARgamma insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells. J Bone Miner Metab 2005;23:275-9.
-
(2005)
J Bone Miner Metab
, vol.23
, pp. 275-279
-
-
Kawaguchi, H.1
Akune, T.2
Yamaguchi, M.3
Ohba, S.4
Ogata, N.5
Chung, U.I.6
-
110
-
-
57349116705
-
Inhibition of calcifying nodule formation in cultured porcine aortic valve cells by nitric oxide donors
-
Kennedy JA, Hua X, Mishra K, Murphy GA, Rosenkranz AC, Horowitz JD. Inhibition of calcifying nodule formation in cultured porcine aortic valve cells by nitric oxide donors. Eur J Pharmacol 2009;602:28-35.
-
(2009)
Eur J Pharmacol
, vol.602
, pp. 28-35
-
-
Kennedy, J.A.1
Hua, X.2
Mishra, K.3
Murphy, G.A.4
Rosenkranz, A.C.5
Horowitz, J.D.6
-
111
-
-
20044364836
-
Atorvastatin inhibits calcification and enhances nitric oxide synthase production in the hypercholesterolaemic aortic valve
-
Rajamannan NM, Subramaniam M, Stock SR, Stone NJ, Springett M, Ignatiev KI, et al. Atorvastatin inhibits calcification and enhances nitric oxide synthase production in the hypercholesterolaemic aortic valve. Heart 2005;91:806-10.
-
(2005)
Heart
, vol.91
, pp. 806-810
-
-
Rajamannan, N.M.1
Subramaniam, M.2
Stock, S.R.3
Stone, N.J.4
Springett, M.5
Ignatiev, K.I.6
-
112
-
-
47249157776
-
Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling
-
Byon CH, Javed A, Dai Q, Kappes JC, Clemens TL, Darley-Usmar VM, et al. Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling. J Biol Chem 2008;283:15319-27.
-
(2008)
J Biol Chem
, vol.283
, pp. 15319-15327
-
-
Byon, C.H.1
Javed, A.2
Dai, Q.3
Kappes, J.C.4
Clemens, T.L.5
Darley-Usmar, V.M.6
-
113
-
-
84887497888
-
Aortic valvular interstitial cells apoptosis and calcification are mediated by TNF-related apoptosis-inducing ligand
-
Galeone A, Brunetti G, Oranger A, Greco G, Di Benedetto A, Mori G, et al. Aortic valvular interstitial cells apoptosis and calcification are mediated by TNF-related apoptosis-inducing ligand. Int J Cardiol 2013;169:296-304.
-
(2013)
Int J Cardiol
, vol.169
, pp. 296-304
-
-
Galeone, A.1
Brunetti, G.2
Oranger, A.3
Greco, G.4
Di Benedetto, A.5
Mori, G.6
-
114
-
-
73949092806
-
Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression
-
Benton JA, Kern HB, Leinwand LA, Mariner PD, Anseth KS. Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression. Arterioscler Thromb Vasc Biol 2009;29:1950-7.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 1950-1957
-
-
Benton, J.A.1
Kern, H.B.2
Leinwand, L.A.3
Mariner, P.D.4
Anseth, K.S.5
-
115
-
-
84885072423
-
Endoplasmic Reticulum Stress Participates in Aortic Valve Calcification in Hypercholesterolemic Animals
-
Cai ZJ, Li F, Gong W, Liu WJ, Duan QL, Chen C, et al. Endoplasmic Reticulum Stress Participates in Aortic Valve Calcification in Hypercholesterolemic Animals. Arterioscler Thromb Vasc 2013;33:2345-54.
-
(2013)
Arterioscler Thromb Vasc
, vol.33
, pp. 2345-2354
-
-
Cai, Z.J.1
Li, F.2
Gong, W.3
Liu, W.J.4
Duan, Q.L.5
Chen, C.6
-
116
-
-
33646466212
-
Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation
-
Caira FC, Stock SR, Gleason TG, McGee EC, Huang J, Bonow RO, et al. Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation. J Am Coll Cardiol 2006;47:1707-12.
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 1707-1712
-
-
Caira, F.C.1
Stock, S.R.2
Gleason, T.G.3
McGee, E.C.4
Huang, J.5
Bonow, R.O.6
-
117
-
-
19944425114
-
Triglycidylamine crosslinking of porcine aortic valve cusps or bovine pericardium results in improved biocompatibility, biomechanics, and calcification resistance: Chemical and biological mechanisms
-
Connolly JM, Alferiev I, Clark-Gruel JN, Eidelman N, Sacks M, Palmatory E, et al. Triglycidylamine crosslinking of porcine aortic valve cusps or bovine pericardium results in improved biocompatibility, biomechanics, and calcification resistance: chemical and biological mechanisms. Am J Pathol 2005;166:1-13.
-
(2005)
Am J Pathol
, vol.166
, pp. 1-13
-
-
Connolly, J.M.1
Alferiev, I.2
Clark-Gruel, J.N.3
Eidelman, N.4
Sacks, M.5
Palmatory, E.6
-
118
-
-
84878255608
-
Nanoanalytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification
-
Bertazzo S, Gentleman E, Cloyd KL, Chester AH, Yacoub MH, Stevens MM. Nanoanalytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification. Nat Mater 2013;12:576-83.
-
(2013)
Nat Mater
, vol.12
, pp. 576-583
-
-
Bertazzo, S.1
Gentleman, E.2
Cloyd, K.L.3
Chester, A.H.4
Yacoub, M.H.5
Stevens, M.M.6
-
119
-
-
1242351794
-
Raman spectroscopy for diagnosis of calcification in human heart valves
-
Otero EU, Sathaiah S, Silveira L, Pomerantzeff PMA, Pasqualucci CAG. Raman spectroscopy for diagnosis of calcification in human heart valves. Spectrosc Int J 2004;18:75-84.
-
(2004)
Spectrosc Int J
, vol.18
, pp. 75-84
-
-
Otero, E.U.1
Sathaiah, S.2
Silveira, L.3
Pomerantzeff, P.M.A.4
Pasqualucci, C.A.G.5
-
120
-
-
79960969604
-
Detection of microcalcification in tissue with Raman spectroscopy
-
Tzang O, Kfir K, Flaxer E, Cheshnovsky O, Einav S. Detection of microcalcification in tissue with Raman spectroscopy. Cardiovasc Eng Technol 2011;2:228-33.
-
(2011)
Cardiovasc Eng Technol
, vol.2
, pp. 228-233
-
-
Tzang, O.1
Kfir, K.2
Flaxer, E.3
Cheshnovsky, O.4
Einav, S.5
-
122
-
-
0037469048
-
Mechanisms of bioprosthetic heart valve calcification
-
Brockbank KG, Song YC. Mechanisms of bioprosthetic heart valve calcification. Transplantation 2003;75:1133-5.
-
(2003)
Transplantation
, vol.75
, pp. 1133-1135
-
-
Brockbank, K.G.1
Song, Y.C.2
-
123
-
-
84904681695
-
-
Accessed 07, 2014, at
-
Atomic absorption spectroscopy. Accessed 07, 2014, at http://www.kau.edu.sa/Files/130002/Files/6785-AAs.pdf.
-
Atomic Absorption Spectroscopy
-
-
-
124
-
-
2342559147
-
An Alizarin red-based assay of mineralization by adherent cells in culture: Comparison with cetylpyridinium chloride extraction
-
Gregory CA, Gunn WG, Peister A, Prockop DJ. An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction. Anal Biochem 2004;329:77-84.
-
(2004)
Anal Biochem
, vol.329
, pp. 77-84
-
-
Gregory, C.A.1
Gunn, W.G.2
Peister, A.3
Prockop, D.J.4
-
125
-
-
84920743155
-
-
Accessed 07, 2014, at
-
von Kossa's Method - Calcium. Accessed 07, 2014, at http://library.med.utah.edu/WebPath/HISTHTML/MANUALS/VONKOSSA.PDF.
-
Von Kossa's Method - Calcium
-
-
-
126
-
-
0042659529
-
Von Kossa staining alone is not sufficient to confirm that mineralization in vitro represents bone formation
-
Bonewald LF, Harris SE, Rosser J, Dallas MR, Dallas SL, Camacho NP, et al. von Kossa staining alone is not sufficient to confirm that mineralization in vitro represents bone formation. Calcif Tissue Int 2003;72:537-47.
-
(2003)
Calcif Tissue Int
, vol.72
, pp. 537-547
-
-
Bonewald, L.F.1
Harris, S.E.2
Rosser, J.3
Dallas, M.R.4
Dallas, S.L.5
Camacho, N.P.6
-
127
-
-
0027161363
-
The von Kossa reaction for calcium deposits: Silver lactate staining increases sensitivity and reduces background
-
Rungby J, Kassem M, Eriksen EF, Danscher G. The von Kossa reaction for calcium deposits: silver lactate staining increases sensitivity and reduces background. Histochem J 1993;25:446-51.
-
(1993)
Histochem J
, vol.25
, pp. 446-451
-
-
Rungby, J.1
Kassem, M.2
Eriksen, E.F.3
Danscher, G.4
-
129
-
-
0025731731
-
Arsenazo III: An improvement of the routine calcium determination in serum
-
Janssen JW, Helbing AR. Arsenazo III: an improvement of the routine calcium determination in serum. Eur J Clin Chem Clin Biochem 1991;29:197-201.
-
(1991)
Eur J Clin Chem Clin Biochem
, vol.29
, pp. 197-201
-
-
Janssen, J.W.1
Helbing, A.R.2
-
130
-
-
84920743153
-
-
Accessed 07, 2014, at
-
Calcium oCPC. Accessed 07, 2014, at https://www.beckmancoulter.com/wsrportal/techdocs?docname=/cis/BAOSR6x13/%25%25/EN-CALCIUM%20(oCPC).pdf; 2009.
-
(2009)
Calcium OCPC
-
-
-
131
-
-
34848906634
-
Characterization of the calcification of cardiac valve bioprostheses by environmental scanning electron microscopy and vibrational spectroscopy
-
Delogne C, Lawford PV, Habesch SM, Carolan VA. Characterization of the calcification of cardiac valve bioprostheses by environmental scanning electron microscopy and vibrational spectroscopy. J Microsc 2007;228:62-77.
-
(2007)
J Microsc
, vol.228
, pp. 62-77
-
-
Delogne, C.1
Lawford, P.V.2
Habesch, S.M.3
Carolan, V.A.4
-
135
-
-
16644366212
-
Influence of receptor activator of nuclear factor kappa B on human aortic valve myofibroblasts
-
Kaden JJ, Dempfle CE, Kilic R, Sarikoc A, Hagl S, Lang S, et al. Influence of receptor activator of nuclear factor kappa B on human aortic valve myofibroblasts. Exp Mol Pathol 2005;78:36-40.
-
(2005)
Exp Mol Pathol
, vol.78
, pp. 36-40
-
-
Kaden, J.J.1
Dempfle, C.E.2
Kilic, R.3
Sarikoc, A.4
Hagl, S.5
Lang, S.6
-
136
-
-
84920748754
-
Ultrafine structure of human aortic valve calcific deposits
-
Grases F, Sohnel O, Zelenkova M. Ultrafine structure of human aortic valve calcific deposits. J Cytol Histol 2014;5:214.
-
(2014)
J Cytol Histol
, vol.5
, pp. 214
-
-
Grases, F.1
Sohnel, O.2
Zelenkova, M.3
-
137
-
-
38349058020
-
Supramolecular structure of human aortic valve and pericardial xenograft material: Atomic force microscopy study
-
Jastrzebska M, Mroz I, Barwinski B, Zalewska-Rejdak J, Turek A, Cwalina B. Supramolecular structure of human aortic valve and pericardial xenograft material: atomic force microscopy study. J Mater Sci Mater Med 2008;19:249-56.
-
(2008)
J Mater Sci Mater Med
, vol.19
, pp. 249-256
-
-
Jastrzebska, M.1
Mroz, I.2
Barwinski, B.3
Zalewska-Rejdak, J.4
Turek, A.5
Cwalina, B.6
-
138
-
-
82955245370
-
High-density lipoproteins (HDL) are present in stenotic aortic valves and may interfere with the mechanisms of valvular calcification
-
Lommi JI, Kovanen PT, Jauhiainen M, Lee-Rueckert M, Kupari M, Helske S. High-density lipoproteins (HDL) are present in stenotic aortic valves and may interfere with the mechanisms of valvular calcification. Atherosclerosis 2011;219:538-44.
-
(2011)
Atherosclerosis
, vol.219
, pp. 538-544
-
-
Lommi, J.I.1
Kovanen, P.T.2
Jauhiainen, M.3
Lee-Rueckert, M.4
Kupari, M.5
Helske, S.6
-
140
-
-
33644805453
-
Correlation between heart valve interstitial cell stiffness and transvalvular pressure: Implications for collagen biosynthesis
-
Merryman WD, Youn I, Lukoff HD, Krueger PM, Guilak F, Hopkins RA, et al. Correlation between heart valve interstitial cell stiffness and transvalvular pressure: implications for collagen biosynthesis. Am J Physiol Heart Circ Physiol 2006;290:H224-31.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
, pp. H224-H231
-
-
Merryman, W.D.1
Youn, I.2
Lukoff, H.D.3
Krueger, P.M.4
Guilak, F.5
Hopkins, R.A.6
|