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Volumn 26, Issue 8, 2006, Pages 1721-1728

Pathogenesis of calcific aortic valve disease: A disease process comes of age (and a good deal more)

Author keywords

Angiotensin II; Aortic valve disease; Calcification; Lipoproteins; Matrix

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LIPOPROTEIN; OLMESARTAN; OSTEOPONTIN;

EID: 33746860419     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000227513.13697.ac     Document Type: Short Survey
Times cited : (254)

References (79)
  • 2
    • 0033565955 scopus 로고    scopus 로고
    • Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly
    • Otto CM, Lind BK, Kitzman DW, Gersh BJ, Siscovick DS. Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly [see comments]. N Engl J Med. 1999;341:142-147.
    • (1999) N Engl J Med , vol.341 , pp. 142-147
    • Otto, C.M.1    Lind, B.K.2    Kitzman, D.W.3    Gersh, B.J.4    Siscovick, D.S.5
  • 3
    • 0027477079 scopus 로고
    • Prevalence of aortic valve abnormalities in the elderly: An echocardiographic study of a random population sample
    • Lindroos M, Kupari M, Heikkila J, Tilvis R. Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample. J Am Coll Cardiol. 1993;21:1220-1225.
    • (1993) J Am Coll Cardiol , vol.21 , pp. 1220-1225
    • Lindroos, M.1    Kupari, M.2    Heikkila, J.3    Tilvis, R.4
  • 4
    • 14044262240 scopus 로고    scopus 로고
    • Frequency by decades of unicuspid, bicuspid, and tricuspid aortic valves in adults having isolated aortic valve replacement for aortic stenosis, with or without associated aortic regurgitation
    • Roberts WC, Ko JM. Frequency by decades of unicuspid, bicuspid, and tricuspid aortic valves in adults having isolated aortic valve replacement for aortic stenosis, with or without associated aortic regurgitation. Circulation. 2005;111:920-925.
    • (2005) Circulation , vol.111 , pp. 920-925
    • Roberts, W.C.1    Ko, J.M.2
  • 6
    • 0000955180 scopus 로고
    • Aging changes in the aortic and mitral valves: Histologic and histochemical studies, with observations on the pathogenesis of calcific aortic stenosis and calcification of the mitral annulus
    • Sell S, Scully RE. Aging changes in the aortic and mitral valves: histologic and histochemical studies, with observations on the pathogenesis of calcific aortic stenosis and calcification of the mitral annulus. Am J Pathol. 1965;46:345-365.
    • (1965) Am J Pathol , vol.46 , pp. 345-365
    • Sell, S.1    Scully, R.E.2
  • 7
    • 0028329052 scopus 로고
    • Accumulation of T lymphocytes and expression of interleukin-2 receptors in nonrheumatic stenotic aortic valves
    • Olsson M, Dalsgaard CJ, Haegerstrand A, Rosenqvist M, Ryden L, Nilsson J. Accumulation of T lymphocytes and expression of interleukin-2 receptors in nonrheumatic stenotic aortic valves. J Am Coll Cardiol. 1994;23:1162-1170.
    • (1994) J Am Coll Cardiol , vol.23 , pp. 1162-1170
    • Olsson, M.1    Dalsgaard, C.J.2    Haegerstrand, A.3    Rosenqvist, M.4    Ryden, L.5    Nilsson, J.6
  • 8
    • 0027991976 scopus 로고
    • Characterization of the early lesion of 'degenerative' valvular aortic stenosis. Histological and immunohistochemical studies
    • Otto CM, Kuusisto J, Reichenbach DD, Gown AM, O'Brien KD. Characterization of the early lesion of 'degenerative' valvular aortic stenosis. Histological and immunohistochemical studies. Circulation. 1994;90:844-853.
    • (1994) Circulation , vol.90 , pp. 844-853
    • Otto, C.M.1    Kuusisto, J.2    Reichenbach, D.D.3    Gown, A.M.4    O'Brien, K.D.5
  • 9
    • 0028081392 scopus 로고
    • Expression of HLA-DR antigen and smooth muscle cell differentiation markers by valvular fibroblasts in degenerative aortic stenosis
    • Olsson M, Rosenqvist M, Nilsson J. Expression of HLA-DR antigen and smooth muscle cell differentiation markers by valvular fibroblasts in degenerative aortic stenosis. J Am Coll Cardiol. 1994;24:1664-1671.
    • (1994) J Am Coll Cardiol , vol.24 , pp. 1664-1671
    • Olsson, M.1    Rosenqvist, M.2    Nilsson, J.3
  • 10
    • 0014809688 scopus 로고
    • The pathogenesis of atherosclerosis of the mitral and aortic valves
    • Walton KW, Williamson N, Johnson AG. The pathogenesis of atherosclerosis of the mitral and aortic valves. J Pathol. 1970;101:205-220.
    • (1970) J Pathol , vol.101 , pp. 205-220
    • Walton, K.W.1    Williamson, N.2    Johnson, A.G.3
  • 12
    • 0032936072 scopus 로고    scopus 로고
    • Presence of oxidized low density lipoprotein in nonrheumatic stenotic aortic valves
    • Olsson M, Thyberg J, Nilsson J. Presence of oxidized low density lipoprotein in nonrheumatic stenotic aortic valves. Arterioscler Thromb Vasc Biol. 1999;19:1218-1222.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1218-1222
    • Olsson, M.1    Thyberg, J.2    Nilsson, J.3
  • 18
    • 24644510707 scopus 로고    scopus 로고
    • Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp5 receptor pathway
    • Rajamannan NM, Subramaniam M, Caira F, Stock SR, Spelsberg TC. Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp5 receptor pathway. Circulation. 2005;112:I229-I234.
    • (2005) Circulation , vol.112
    • Rajamannan, N.M.1    Subramaniam, M.2    Caira, F.3    Stock, S.R.4    Spelsberg, T.C.5
  • 21
    • 0036785975 scopus 로고    scopus 로고
    • T lymphocyte infiltration in non-rheumatic aortic stenosis: A comparative descriptive study between tricuspid and bicuspid aortic valves
    • Wallby L, Janerot-Sjoberg B, Steffensen T, Broqvist M. T lymphocyte infiltration in non-rheumatic aortic stenosis: a comparative descriptive study between tricuspid and bicuspid aortic valves. Heart. 2002;88:348-351.
    • (2002) Heart , vol.88 , pp. 348-351
    • Wallby, L.1    Janerot-Sjoberg, B.2    Steffensen, T.3    Broqvist, M.4
  • 22
    • 0034768262 scopus 로고    scopus 로고
    • The vitamin D receptor genotype predisposes to the development of calcific aortic valve stenosis
    • Ortlepp JR, Hoffmann R, Ohme F, Lauscher J, Bleckmann F, Hanrath P. The vitamin D receptor genotype predisposes to the development of calcific aortic valve stenosis. Heart. 2001;85:635-638.
    • (2001) Heart , vol.85 , pp. 635-638
    • Ortlepp, J.R.1    Hoffmann, R.2    Ohme, F.3    Lauscher, J.4    Bleckmann, F.5    Hanrath, P.6
  • 23
    • 0142053965 scopus 로고    scopus 로고
    • Association between apolipoprotein e alleles and calcific valvular heart disease
    • Novaro GM, Sachar R, Pearce GL, Sprecher DL, Griffin BP. Association between apolipoprotein E alleles and calcific valvular heart disease. Circulation. 2003;108:1804-1808.
    • (2003) Circulation , vol.108 , pp. 1804-1808
    • Novaro, G.M.1    Sachar, R.2    Pearce, G.L.3    Sprecher, D.L.4    Griffin, B.P.5
  • 26
    • 0037414072 scopus 로고    scopus 로고
    • Experimental aortic valve stenosis in rabbits
    • Drolet MC, Arsenault M, Couet J. Experimental aortic valve stenosis in rabbits. J Am Coll Cardiol. 2003;41:1211-1217.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1211-1217
    • Drolet, M.C.1    Arsenault, M.2    Couet, J.3
  • 27
    • 33748103611 scopus 로고    scopus 로고
    • Angiotensin Receptor 1 Blocker Reduces Atherosclerotic Changes of Aortic Valve in Hypercholesterolemic Rabbit Model
    • Arishiro K, Hoshiga M, Negoro N, Okabe T, Ishihara T, Hanafusa T Angiotensin Receptor 1 Blocker Reduces Atherosclerotic Changes of Aortic Valve in Hypercholesterolemic Rabbit Model. J Am Coll Cardiol. 2006;47:284A-285A.
    • (2006) J Am Coll Cardiol , vol.47
    • Arishiro, K.1    Hoshiga, M.2    Negoro, N.3    Okabe, T.4    Ishihara, T.5    Hanafusa, T.6
  • 30
    • 32644445773 scopus 로고    scopus 로고
    • A high fat/high carbohydrate diet induces aortic valve disease in C57BL/6J mice
    • Drolet MC, Roussel E, Deshaies Y, Couet J, Arsenault M. A high fat/high carbohydrate diet induces aortic valve disease in C57BL/6J mice. J Am Coll Cardiol. 2006;47:850-855.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 850-855
    • Drolet, M.C.1    Roussel, E.2    Deshaies, Y.3    Couet, J.4    Arsenault, M.5
  • 31
    • 0035975938 scopus 로고    scopus 로고
    • Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis
    • Novaro GM, Tiong IY, Pearce GL, Lauer MS, Sprecher DL, Griffin BP. Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis. Circulation. 2001;104:2205-2209.
    • (2001) Circulation , vol.104 , pp. 2205-2209
    • Novaro, G.M.1    Tiong, I.Y.2    Pearce, G.L.3    Lauer, M.S.4    Sprecher, D.L.5    Griffin, B.P.6
  • 32
    • 0037145893 scopus 로고    scopus 로고
    • Association of cholesterol levels, hydroxymethylglutaryl coenzyme-A reductase inhibitor treatment, and progression of aortic stenosis in the community
    • Bellamy MF, Pellikka PA, Klarich KW, Tajik AJ, Enriquez-Sarano M. Association of cholesterol levels, hydroxymethylglutaryl coenzyme-A reductase inhibitor treatment, and progression of aortic stenosis in the community. J Am Coll Cardiol. 2002;40:1723-1730.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 1723-1730
    • Bellamy, M.F.1    Pellikka, P.A.2    Klarich, K.W.3    Tajik, A.J.4    Enriquez-Sarano, M.5
  • 34
    • 0035899912 scopus 로고    scopus 로고
    • Progression of aortic valve calcification: Association with coronary atherosclerosis and cardiovascular risk factors
    • Pohle K, Maffert R, Ropers D, Moshage W, Stilianakis N, Daniel WG, Achenbach S. Progression of aortic valve calcification: association with coronary atherosclerosis and cardiovascular risk factors. Circulation. 2001;104:1927-1932.
    • (2001) Circulation , vol.104 , pp. 1927-1932
    • Pohle, K.1    Maffert, R.2    Ropers, D.3    Moshage, W.4    Stilianakis, N.5    Daniel, W.G.6    Achenbach, S.7
  • 35
    • 0037197017 scopus 로고    scopus 로고
    • HMG CoA reductase inhibitor (statin) and aortic valve calcium
    • Shavelle DM, Takasu J, Budoff MJ, Mao S, O'Brien KD. HMG CoA reductase inhibitor (statin) and aortic valve calcium. Lancet. 2002;359:1125-1126.
    • (2002) Lancet , vol.359 , pp. 1125-1126
    • Shavelle, D.M.1    Takasu, J.2    Budoff, M.J.3    Mao, S.4    O'Brien, K.D.5
  • 38
    • 0026320323 scopus 로고
    • Development and progression of aortic valve stenosis: Atherosclerosis risk factors - A causal relationship? A clinical morphologic study
    • Mohler ER, Sheridan MJ, Nichols R, Harvey WP, Waller BF. Development and progression of aortic valve stenosis: atherosclerosis risk factors - a causal relationship? A clinical morphologic study. Clin Cardiol. 1991;14:995-999.
    • (1991) Clin Cardiol , vol.14 , pp. 995-999
    • Mohler, E.R.1    Sheridan, M.J.2    Nichols, R.3    Harvey, W.P.4    Waller, B.F.5
  • 39
    • 0035885130 scopus 로고    scopus 로고
    • Association of coronary risk factors and use of statins with progression of mild valvular aortic stenosis in older persons
    • Aronow WS, Ahn C, Kronzon I, Goldman ME. Association of coronary risk factors and use of statins with progression of mild valvular aortic stenosis in older persons. Am J Cardiol. 2001;88:693-695.
    • (2001) Am J Cardiol , vol.88 , pp. 693-695
    • Aronow, W.S.1    Ahn, C.2    Kronzon, I.3    Goldman, M.E.4
  • 40
    • 0023232653 scopus 로고
    • Calcific aortic stenosis: A complication of chronic uraemia
    • Maher ER, Pazianas M, Curtis JR. Calcific aortic stenosis: a complication of chronic uraemia. Nephron. 1987;47:119-122.
    • (1987) Nephron , vol.47 , pp. 119-122
    • Maher, E.R.1    Pazianas, M.2    Curtis, J.R.3
  • 41
    • 3242696702 scopus 로고    scopus 로고
    • Valvular calcification in hemodialysis patients randomized to calcium-based phosphorus binders or sevelamer
    • Raggi P, Bommer J, Chertow GM. Valvular calcification in hemodialysis patients randomized to calcium-based phosphorus binders or sevelamer. J Heart Valve Dis. 2004;13:134-141.
    • (2004) J Heart Valve Dis , vol.13 , pp. 134-141
    • Raggi, P.1    Bommer, J.2    Chertow, G.M.3
  • 44
    • 0034641588 scopus 로고    scopus 로고
    • Are atherosclerotic processes involved in aortic-valve calcification?
    • Mohler ER III. Are atherosclerotic processes involved in aortic-valve calcification? Lancet. 2000;356:524-525.
    • (2000) Lancet , vol.356 , pp. 524-525
    • Mohler III, E.R.1
  • 47
    • 0033735304 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression in nonrheumatic aortic stenosis
    • Edep ME, Shirani J, Wolf P, Brown DL. Matrix metalloproteinase expression in nonrheumatic aortic stenosis. Cardiovasc Pathol. 2000;9:281-286.
    • (2000) Cardiovasc Pathol , vol.9 , pp. 281-286
    • Edep, M.E.1    Shirani, J.2    Wolf, P.3    Brown, D.L.4
  • 48
    • 0034987229 scopus 로고    scopus 로고
    • Expression of MMP2, MMP9, MT1-MMP, TIMP1, and TIMP2 mRNA in valvular lesions of the heart
    • Soini Y, Satta J, Maatta M, Autio-Harmainen H. Expression of MMP2, MMP9, MT1-MMP, TIMP1, and TIMP2 mRNA in valvular lesions of the heart. J Pathol. 2001;194:225-231.
    • (2001) J Pathol , vol.194 , pp. 225-231
    • Soini, Y.1    Satta, J.2    Maatta, M.3    Autio-Harmainen, H.4
  • 49
    • 0028063408 scopus 로고
    • Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
    • Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest. 1994;94:2493-2503.
    • (1994) J Clin Invest , vol.94 , pp. 2493-2503
    • Galis, Z.S.1    Sukhova, G.K.2    Lark, M.W.3    Libby, P.4
  • 51
    • 0028836794 scopus 로고
    • Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases
    • Galis ZS, Sukhova GK, Kranzhofer R, Clark S, Libby P. Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases. Proc Natl Acad Sci U S A. 1995;92:402-406.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 402-406
    • Galis, Z.S.1    Sukhova, G.K.2    Kranzhofer, R.3    Clark, S.4    Libby, P.5
  • 52
    • 0032508364 scopus 로고    scopus 로고
    • Comparison of apolipoprotein and proteoglycan deposits in human coronary atherosclerotic plaques: Colocalization of biglycan with apolipoproteins
    • O'Brien KD, Olin KL, Alpers CE, Chiu W, Ferguson M, Hudkins K, Wight TN, Chait A. Comparison of apolipoprotein and proteoglycan deposits in human coronary atherosclerotic plaques: colocalization of biglycan with apolipoproteins. Circulation. 1998;98:519-527.
    • (1998) Circulation , vol.98 , pp. 519-527
    • O'Brien, K.D.1    Olin, K.L.2    Alpers, C.E.3    Chiu, W.4    Ferguson, M.5    Hudkins, K.6    Wight, T.N.7    Chait, A.8
  • 53
    • 33748094353 scopus 로고
    • Regional accumulation of proteoglycans in lesions of " degenerative" valvular aortic stenosis and their relationship to apolipoproteins
    • O'Brien KD, Otto CM, Reichenbach DD, Alpers CE, Wight TN. Regional accumulation of proteoglycans in lesions of "degenerative" valvular aortic stenosis and their relationship to apolipoproteins. Circulation. 1995;92(suppl I):I-612.
    • (1995) Circulation , vol.92 , Issue.1 SUPPL.
    • O'Brien, K.D.1    Otto, C.M.2    Reichenbach, D.D.3    Alpers, C.E.4    Wight, T.N.5
  • 54
    • 0024529015 scopus 로고
    • Cell biology of arterial proteoglycans
    • Wight TN. Cell biology of arterial proteoglycans. Arteriosclerosis. 1989;9:1-20.
    • (1989) Arteriosclerosis , vol.9 , pp. 1-20
    • Wight, T.N.1
  • 55
    • 0031036417 scopus 로고    scopus 로고
    • Possible functional interactions of apolipoprotein B-100 segments that associate with cell proteoglycans and the ApoB/E receptor
    • Olsson U, Camejo G, Hurt-Camejo E, Elfsber K, Wiklund O, Bondjers G. Possible functional interactions of apolipoprotein B-100 segments that associate with cell proteoglycans and the ApoB/E receptor. Arterioscler Thromb Vasc Biol. 1997;17:149-155.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 149-155
    • Olsson, U.1    Camejo, G.2    Hurt-Camejo, E.3    Elfsber, K.4    Wiklund, O.5    Bondjers, G.6
  • 58
    • 14644435807 scopus 로고    scopus 로고
    • Paradoxical effects of statins on aortic valve myofibroblasts and osteoblasts: Implications for end-stage valvular heart disease
    • Wu B, Elmariah S, Kaplan FS, Cheng G, Mohler ER III. Paradoxical effects of statins on aortic valve myofibroblasts and osteoblasts: implications for end-stage valvular heart disease. Arterioscler Thromb Vasc Biol. 2005;25:592-597.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 592-597
    • Wu, B.1    Elmariah, S.2    Kaplan, F.S.3    Cheng, G.4    Mohler III, E.R.5
  • 60
    • 0344196793 scopus 로고    scopus 로고
    • Induction of myocardial biglycan in heart failure in rats - An extracellular matrix component targeted by AT(1) receptor antagonism
    • Ahmed MS, Oie E, Vinge LE, Yndestad A, Andersen GG, Andersson Y, Attramadal T, Attramadal H. Induction of myocardial biglycan in heart failure in rats - an extracellular matrix component targeted by AT(1) receptor antagonism. Cardiovasc Res. 2003;60:557-568.
    • (2003) Cardiovasc Res , vol.60 , pp. 557-568
    • Ahmed, M.S.1    Oie, E.2    Vinge, L.E.3    Yndestad, A.4    Andersen, G.G.5    Andersson, Y.6    Attramadal, T.7    Attramadal, H.8
  • 63
    • 0020520113 scopus 로고
    • Calcific diseases. A concept
    • Anderson HC. Calcific diseases. A concept. Arch Pathol Lab Med. 1983;107:341-348.
    • (1983) Arch Pathol Lab Med , vol.107 , pp. 341-348
    • Anderson, H.C.1
  • 66
    • 0035408476 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 is associated with tenascin-C in calcific aortic stenosis
    • Jian B, Jones PL, Li Q, Mohler ER III, Schoen FJ, Levy RJ. Matrix metalloproteinase-2 is associated with tenascin-C in calcific aortic stenosis. Am J Pathol. 2001;159:321-327.
    • (2001) Am J Pathol , vol.159 , pp. 321-327
    • Jian, B.1    Jones, P.L.2    Li, Q.3    Mohler III, E.R.4    Schoen, F.J.5    Levy, R.J.6
  • 67
    • 14544283020 scopus 로고    scopus 로고
    • Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: A potential mechanism for accelerated vascular calcification in ESRD
    • Reynolds JL, Joannides AJ, Skepper JN, McNair R, Schurgers LJ, Proudfoot D, Jahnen-Dechent W, Weissberg PL, Shanahan CM. Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol. 2004;15:2857-2867.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2857-2867
    • Reynolds, J.L.1    Joannides, A.J.2    Skepper, J.N.3    McNair, R.4    Schurgers, L.J.5    Proudfoot, D.6    Jahnen-Dechent, W.7    Weissberg, P.L.8    Shanahan, C.M.9
  • 69
    • 24944487122 scopus 로고    scopus 로고
    • Regression of medial elastocalcinosis in rat aorta: A new vascular function for carbonic anhydrase
    • Essalihi R, Dao HH, Gilbert LA, Bouvet C, Semerjian Y, McKee MD, Moreau P. Regression of medial elastocalcinosis in rat aorta: a new vascular function for carbonic anhydrase. Circulation. 2005;112:1628-1635.
    • (2005) Circulation , vol.112 , pp. 1628-1635
    • Essalihi, R.1    Dao, H.H.2    Gilbert, L.A.3    Bouvet, C.4    Semerjian, Y.5    McKee, M.D.6    Moreau, P.7
  • 70
    • 0027367239 scopus 로고
    • Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques
    • Giachelli CM, Bae N, Almeida M, Denhardt DT, Alpers CE, Schwartz SM. Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J Clin Invest. 1993;92:1686-1696.
    • (1993) J Clin Invest , vol.92 , pp. 1686-1696
    • Giachelli, C.M.1    Bae, N.2    Almeida, M.3    Denhardt, D.T.4    Alpers, C.E.5    Schwartz, S.M.6
  • 71
    • 0023238604 scopus 로고
    • Correlation of serum lipids, calcium, and phosphorus, diabetes mellitus and history of systemic hypertension with presence or absence of calcified or thickened aortic cusps or root in elderly patients
    • Aronow WS, Schwartz KS, Koenigsberg M. Correlation of serum lipids, calcium, and phosphorus, diabetes mellitus and history of systemic hypertension with presence or absence of calcified or thickened aortic cusps or root in elderly patients. Am J Cardiol. 1987;59:998-999.
    • (1987) Am J Cardiol , vol.59 , pp. 998-999
    • Aronow, W.S.1    Schwartz, K.S.2    Koenigsberg, M.3
  • 73
    • 0031974284 scopus 로고    scopus 로고
    • Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair
    • Wozney JM, Rosen V. Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair. Clin Orthop Relat Res. 1998;26-37.
    • (1998) Clin Orthop Relat Res , pp. 26-37
    • Wozney, J.M.1    Rosen, V.2
  • 76
    • 33645351946 scopus 로고    scopus 로고
    • BMP signaling is required for RUNX2-dependent induction of the osteoblast phenotype
    • Phimphilai M, Zhao Z, Boules H, Roca H, Franceschi RT. BMP signaling is required for RUNX2-dependent induction of the osteoblast phenotype. J Bone Miner Res. 2006;21:637-646.
    • (2006) J Bone Miner Res , vol.21 , pp. 637-646
    • Phimphilai, M.1    Zhao, Z.2    Boules, H.3    Roca, H.4    Franceschi, R.T.5
  • 77
    • 33646157733 scopus 로고    scopus 로고
    • Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification
    • Li X, Yang HY, Giachelli CM. Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification. Circ Res. 2006;98:905-912.
    • (2006) Circ Res , vol.98 , pp. 905-912
    • Li, X.1    Yang, H.Y.2    Giachelli, C.M.3
  • 78
    • 0035158955 scopus 로고    scopus 로고
    • Association between calcific aortic stenosis and hypercholesterolemia: Is there a need for a randomized controlled trial of cholesterol-lowering therapy?
    • Chui MC, Newby DE, Panarelli M, Bloomfield P, Boon NA. Association between calcific aortic stenosis and hypercholesterolemia: is there a need for a randomized controlled trial of cholesterol-lowering therapy? Clin Cardiol. 2001;24:52-55.
    • (2001) Clin Cardiol , vol.24 , pp. 52-55
    • Chui, M.C.1    Newby, D.E.2    Panarelli, M.3    Bloomfield, P.4    Boon, N.A.5


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