Myocardial contraction and hyaluronic acid mechanotransduction inepithelial-to-mesenchymal transformation of endocardial cells

Biomaterials

Volumn 35, Issue 9, 2014, Pages 2809-2815

  Sewell Loftin, Mary Kathryn ^a   DeLaughter, Daniel M ^b   Peacock, Jon R ^a   Brown, Christopher B ^c   Baldwin, H Scott ^b,c   Barnett, Joey V ^b   Merryman, W David ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

Collagen; Epithelial to mesenchymal transition (EMT); Heart valve; Hyaluronic acid; Mechanical properties

Indexed keywords

COLLAGEN; EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT); HEART VALVE; HYALURONIC ACID; MECHANICAL PROPERTIES;

ANIMALS; CELL PROLIFERATION; CHICKENS; COLLAGEN TYPE I; CROSS-LINKING REAGENTS; ENDOCARDIUM; EPITHELIAL-MESENCHYMAL TRANSITION; HYALURONIC ACID; MECHANOTRANSDUCTION, CELLULAR; METHACRYLATES; MYOCARDIAL CONTRACTION; SIGNAL TRANSDUCTION; TISSUE SCAFFOLDS;

EID: 84894988652     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.12.051     Document Type: Article

References (32)

1. Barnett J.V., Desgrosellier J.S. Early events in valvulogenesis: a signaling perspective. Birth Defects Res C Embryo Today 2003, 69(1):58-72.
2. Olivey H.E., Mundell N.A., Austin A.F., Barnett J.V. Transforming growth factor-beta stimulates epithelial-mesenchymal transformation in the proepicardium. Dev Dyn 2006, 235(1):50-59.
3. Combs M.D., Yutzey K.E. Heart valve development: regulatory networks in development and disease. Circ Res 2009, 105(5):408-421.
4. Hinton R.B., Yutzey K.E. Heart valve structure and function in development and disease. Annu Rev Physiol 2011, 73:29-46.
5. Rodriguez K.J., Piechura L.M., Masters K.S. Regulation of valvular interstitial cell phenotype and function by hyaluronic acid in 2-d and 3-d culture environments. Matrix Biol 2011, 30(1):70-82.
6. Sewell-Loftin M.K., Chun Y.W., Khademhosseini A., Merryman W.D. Emt-inducing biomaterials for heart valve engineering: taking cues from developmental biology. JCardiovasc Transl Res 2011, 4(5):658-671.
7. Armstrong E.J., Bischoff J. Heart valve development - endothelial cell signaling and differentiation. Circ Res 2004, 95(5):459-470.
8. Craig E.A., Parker P., Austin A.F., Barnett J.V., Camenisch T.D. Involvement of the mekk1 signaling pathway in the regulation of epicardial cell behavior by hyaluronan. Cell Signal 2010, 22(6):968-976.
9. Hill C.R., Sanchez N.S., Love J.D., Arrieta J.A., Hong C.C., Brown C.B., et al. Bmp2 signals loss of epithelial character in epicardial cells but requires the type iii tgfbeta receptor to promote invasion. Cell Signal 2012, 24(5):1012-1022.
10. Sanchez N.S., Barnett J.V. Tgfbeta and bmp-2 regulate epicardial cell invasion via tgfbetar3 activation of the par6/smurf1/rhoa pathway. Cell Signal 2012, 24(2):539-548.
11. Townsend T.A., Robinson J.Y., How T., DeLaughter D.M., Blobe G.C., Barnett J.V. Endocardial cell epithelial-mesenchymal transformation requires type iii tgfbeta receptor interaction with gipc. Cell Signal 2012, 24(1):247-256.
12. Chiu Y.N., Norris R.A., Mahler G., Recknagel A., Butcher J.T. Transforming growth factor beta, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: relevance for heart valve tissue engineering. Tissue Eng Part A 2010, 16(11):3375-3383.
13. Stevens M.V., Broka D.M., Parker P., Rogowitz E., Vaillancourt R.R., Camenisch T.D. Mekk3 initiates transforming growth factor beta 2-dependent epithelial-to-mesenchymal transition during endocardial cushion morphogenesis. Circ Res 2008, 103(12):1430-1440.
14. Bernanke D.H., Markwald R.R. Migratory behavior of cardiac cushion tissue cells in a collagen-lattice culture system. Dev Biol 1982, 91(2):235-245.
15. Runyan R.B., Markwald R.R. Invasion of mesenchyme into three-dimensional collagen gels: a regional and temporal analysis of interaction in embryonic heart tissue. Dev Biol 1983, 95(1):108-114.
16. Camenisch T.D., Spicer A.P., Brehm-Gibson T., Biesterfeldt J., Augustine M.L., Calabro A., et al. Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme. JClin Invest 2000, 106(3):349-360.
17. Delaughter D.M., Saint-Jean L., Baldwin H.S., Barnett J.V. What chick and mouse models have taught us about the role of the endocardium in congenital heart disease. Birth Defects Res A Clin Mol Teratol 2011, 91(6):511-525.
18. Lencinas A., Tavares A.L., Barnett J.V., Runyan R.B. Collagen gel analysis of epithelial-mesenchymal transition in the embryo heart: an invitro model system for the analysis of tissue interaction, signal transduction, and environmental effects. Birth Defects Res C Embryo Today 2011, 93(4):298-311.
19. Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V. Requirement of type iii tgf-beta receptor for endocardial cell transformation in the heart. Science 1999, 283(5410):2080-2082.
20. Bernanke D.H., Markwald R.R. Effects of two glycosaminoglycans on seeding of cardiac cushion tissue cells into a collagen-lattice culture system. Anat Rec 1984, 210(1):25-31.
21. Baldwin H.S., Lloyd T.R., Solursh M. Hyaluronate degradation affects ventricular function of the early postlooped embryonic rat heart in situ. Circ Res 1994, 74(2):244-252.
22. Masters K.S., Shah D.N., Leinwand L.A., Anseth K.S. Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. Biomaterials 2005, 26(15):2517-2525.
23. Masters K.S., Shah D.N., Walker G., Leinwand L.A., Anseth K.S. Designing scaffolds for valvular interstitial cells: cell adhesion and function on naturally derived materials. JBiomed Mater Res A 2004, 71(1):172-180.
24. Brigham M.D., Bick A., Lo E., Bendali A., Burdick J.A., Khademhosseini A. Mechanically robust and bioadhesive collagen and photocrosslinkable hyaluronic acid semi-interpenetrating networks. Tissue Eng Part A 2009, 15(7):1645-1653.
25. Chopra A., Murray M.E., Byfield F.J., Mendez M.G., Halleluyan R., Restle D.J., et al. Augmentation of integrin-mediated mechanotransduction by hyaluronic acid. Biomaterials 2014, 35(1):71-82.
26. Merryman W.D. Mechano-potential etiologies of aortic valve disease. JBiomech 2010, 43(1):87-92.
27. Aikawa E., Whittaker P., Farber M., Mendelson K., Padera R.F., Aikawa M., et al. Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. Circulation 2006, 113(10):1344-1352.
28. Smeds K.A., Pfister-Serres A., Miki D., Dastgheib K., Inoue M., Hatchell D.L., et al. Photocrosslinkable polysaccharides for in situ hydrogel formation. JBiomed Mater Res 2001, 54(1):115-121.
29. Smeds K.A., Pfister-Serres A., Hatchell D.L., Grinstaff M.W. Synthesis of a novel polysaccharide hydrogel. JMacromol Sci Pure Appl Chem 1999, A36(7-8):981-989.
30. Sewell-Loftin M.K., Brown C.B., Baldwin H.S., Merryman W.D. Anovel technique for quantifying mouse heart valve leaflet stiffness with atomic force microscopy. JHeart Valve Dis 2012, 21:513-520.
31. Bartman T., Walsh E.C., Wen K.K., McKane M., Ren J., Alexander J., et al. Early myocardial function affects endocardial cushion development in zebrafish. PLoS Biol 2004, 2(5):E129.
32. Rodgers L.S., Lalani S., Hardy K.M., Xiang X., Broka D., Antin P.B., et al. Depolymerized hyaluronan induces vascular endothelial growth factor, a negative regulator of developmental epithelial-to-mesenchymal transformation. Circ Res 2006, 99(6):583-589.