Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve

Circulation

Volumn 105, Issue 22, 2002, Pages 2660-2665

  Rajamannan, Nalini M ^a   Subramaniam, Malayannan ^b   Springett, Margaret ^c   Sebo, Thomas C ^c   Niekrasz, Marek ^a   McConnell, Joseph P ^c   Singh, Ravinder J ^c   Stone, Neil J ^a   Bonow, Robert O ^a   Spelsberg, Thomas C ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Atherosclerosis; Cardiovascular diseases; Lipids; Physiology; Valves

Indexed keywords

ALKALINE PHOSPHATASE; ATORVASTATIN; C REACTIVE PROTEIN; CHOLESTEROL; CYCLINE; DYE; EOSIN; HEMATOXYLIN; MASSON TRICHROME; OSTEOPONTIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CBFA 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA VALVE; AORTA VALVE STENOSIS; ARTICLE; ATHEROSCLEROSIS; BONE MATRIX; BONE MINERALIZATION; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; COMPUTER ANALYSIS; CONTROLLED STUDY; ELECTRON MICROSCOPY; HYPERCHOLESTEROLEMIA; IMAGE ANALYSIS; IMMUNOGOLD LABELING; MACROPHAGE; MALE; MARKER GENE; MORPHOMETRICS; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; QUANTITATIVE ASSAY; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALKALINE PHOSPHATASE; ANIMALS; ANTICHOLESTEREMIC AGENTS; AORTIC VALVE; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CALCINOSIS; CELL DIVISION; CHOLESTEROL; CHOLESTEROL, DIETARY; DISEASE MODELS, ANIMAL; HEART VALVE DISEASES; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERCHOLESTEROLEMIA; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MALE; MICROSCOPY, IMMUNOELECTRON; OSTEOBLASTS; OSTEOPONTIN; PROLIFERATING CELL NUCLEAR ANTIGEN; PYRROLES; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIALOGLYCOPROTEINS;

EID: 0037024284     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000017435.87463.72     Document Type: Article

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