메뉴 건너뛰기




Volumn 77, Issue 1, 2015, Pages 29-35

The promise of psychiatric pharmacogenomics

Author keywords

CYP2C19; CYP2D6; Depression; GWAS; Pharmacogenetics; Schizophrenia

Indexed keywords

ANTIDEPRESSANT AGENT; HLA ANTIGEN; MOOD STABILIZER; NEUROLEPTIC AGENT; PSYCHOTROPIC AGENT;

EID: 84920645334     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2014.09.009     Document Type: Review
Times cited : (46)

References (87)
  • 1
    • 34548181277 scopus 로고    scopus 로고
    • Systematic review of the incidence and characteristics of preventable adverse drug events in ambulatory care
    • L.A. Thomsen, A.G. Winterstein, B. Søndergaard, L.S. Haugbølle, and A. Melander Systematic review of the incidence and characteristics of preventable adverse drug events in ambulatory care Ann Pharmacother 41 2007 1411 1426
    • (2007) Ann Pharmacother , vol.41 , pp. 1411-1426
    • Thomsen, L.A.1    Winterstein, A.G.2    Søndergaard, B.3    Haugbølle, L.S.4    Melander, A.5
  • 2
    • 77949320495 scopus 로고    scopus 로고
    • Pharmacogenetics of idiosyncratic adverse drug reactions
    • J. Uetrecht, Springer-Verlag Berlin
    • M. Pirmohamed Pharmacogenetics of idiosyncratic adverse drug reactions J. Uetrecht, Adverse Drug Reactions 2010 Springer-Verlag Berlin 477 491
    • (2010) Adverse Drug Reactions , pp. 477-491
    • Pirmohamed, M.1
  • 3
    • 69049114189 scopus 로고    scopus 로고
    • Pharmacogenomics of adverse drug reactions: Practical applications and perspectives
    • L. Becquemont Pharmacogenomics of adverse drug reactions: Practical applications and perspectives Pharmacogenomics 10 2009 961 969
    • (2009) Pharmacogenomics , vol.10 , pp. 961-969
    • Becquemont, L.1
  • 4
    • 84872899545 scopus 로고    scopus 로고
    • Pharmacogenomics of drug-metabolizing enzymes: A recent update on clinical implications and endogenous effects
    • S.C. Sim, M. Kacevska, and M. Ingelman-Sundberg Pharmacogenomics of drug-metabolizing enzymes: A recent update on clinical implications and endogenous effects Pharmacogenomics J 13 2013 1 11
    • (2013) Pharmacogenomics J , vol.13 , pp. 1-11
    • Sim, S.C.1    Kacevska, M.2    Ingelman-Sundberg, M.3
  • 6
    • 0022220338 scopus 로고
    • Genetic polymorphism of mephenytoin p(4′)-hydroxylation: Difference between Orientals and Caucasians
    • M. Jurima, T. Inaba, D. Kadar, and W. Kalow Genetic polymorphism of mephenytoin p(4′)-hydroxylation: Difference between Orientals and Caucasians Br J Clin Pharmacol 19 1985 483 487
    • (1985) Br J Clin Pharmacol , vol.19 , pp. 483-487
    • Jurima, M.1    Inaba, T.2    Kadar, D.3    Kalow, W.4
  • 7
    • 0026506140 scopus 로고
    • Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin
    • L. Bertilsson, Y.Q. Lou, Y.L. Du, Y. Liu, T.Y. Kuang, and X.M. Liao Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin Clin Pharmacol Ther 51 1992 388 397
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 388-397
    • Bertilsson, L.1    Lou, Y.Q.2    Du, Y.L.3    Liu, Y.4    Kuang, T.Y.5    Liao, X.M.6
  • 8
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • N. Risch, and K. Merikangas The future of genetic studies of complex human diseases Science 273 1996 1516 1517
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 9
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • 1000 Genomes Project Consortium
    • 1000 Genomes Project Consortium A map of human genome variation from population-scale sequencing Nature 467 2010 1061 1073
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 10
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • International HapMap Consortium
    • International HapMap Consortium A second generation human haplotype map of over 3.1 million SNPs Nature 449 2007 851 861
    • (2007) Nature , vol.449 , pp. 851-861
  • 11
    • 77956331627 scopus 로고    scopus 로고
    • Integrating common and rare genetic variation in diverse human populations
    • International HapMap Consortium
    • International HapMap Consortium Integrating common and rare genetic variation in diverse human populations Nature 467 2010 52 58
    • (2010) Nature , vol.467 , pp. 52-58
  • 14
    • 84861940981 scopus 로고    scopus 로고
    • Pharmacogenomics and personalized medicine in neuropsychiatry
    • F. McMahon, and T. Insel Pharmacogenomics and personalized medicine in neuropsychiatry Neuron 74 2012 773 776
    • (2012) Neuron , vol.74 , pp. 773-776
    • McMahon, F.1    Insel, T.2
  • 15
    • 3142519666 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response
    • J. Kirchheiner, K. Nickchen, M. Bauer, M.L. Wong, J. Licinio, I. Roots, and J. Brockmoller Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response Mol Psychiatry 9 2004 442 473
    • (2004) Mol Psychiatry , vol.9 , pp. 442-473
    • Kirchheiner, J.1    Nickchen, K.2    Bauer, M.3    Wong, M.L.4    Licinio, J.5    Roots, I.6    Brockmoller, J.7
  • 16
    • 29544449443 scopus 로고    scopus 로고
    • Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19
    • J. de Leon, S.C. Armstrong, and K.L. Cozza Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19 Psychosomatics 47 2006 75 85
    • (2006) Psychosomatics , vol.47 , pp. 75-85
    • De Leon, J.1    Armstrong, S.C.2    Cozza, K.L.3
  • 17
    • 84876665512 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants
    • J.K. Hicks, J.J. Swen, C.F. Thorn, K. Sangkuhl, E.D. Kharasch, and V.L. Ellingrod Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants Clin Pharmacol Ther 93 2013 402 408
    • (2013) Clin Pharmacol Ther , vol.93 , pp. 402-408
    • Hicks, J.K.1    Swen, J.J.2    Thorn, C.F.3    Sangkuhl, K.4    Kharasch, E.D.5    Ellingrod, V.L.6
  • 18
    • 30044433660 scopus 로고    scopus 로고
    • Evaluation of outcomes with citalopram for depression using measurement-based care in STAR∗D: Implications for clinical practice
    • M.H. Trivedi, A.J. Rush, S.R. Wisniewski, A.A. Nierenberg, D. Warden, and L. Ritz Evaluation of outcomes with citalopram for depression using measurement-based care in STAR∗D: Implications for clinical practice Am J Psychiatry 163 2006 28 40
    • (2006) Am J Psychiatry , vol.163 , pp. 28-40
    • Trivedi, M.H.1    Rush, A.J.2    Wisniewski, S.R.3    Nierenberg, A.A.4    Warden, D.5    Ritz, L.6
  • 19
    • 0015123855 scopus 로고
    • Differentiation of two genetically specific types of depression by the response to antidepressant drugs
    • C.M.B. Pare, and J.W. Mack Differentiation of two genetically specific types of depression by the response to antidepressant drugs J Med Genet 8 1971 306 309
    • (1971) J Med Genet , vol.8 , pp. 306-309
    • Pare, C.M.B.1    Mack, J.W.2
  • 20
    • 0032167874 scopus 로고    scopus 로고
    • Familial concordance of fluvoxamine response as a tool for differentiating mood disorder pedigrees
    • L. Franchini, A. Serretti, M. Gasperini, and E. Smeraldi Familial concordance of fluvoxamine response as a tool for differentiating mood disorder pedigrees J Psychiatr Res 32 1998 255 259
    • (1998) J Psychiatr Res , vol.32 , pp. 255-259
    • Franchini, L.1    Serretti, A.2    Gasperini, M.3    Smeraldi, E.4
  • 21
    • 57749177273 scopus 로고    scopus 로고
    • Increased carrier prevalence of deficient CYP2C9, CYP2C19 and CYP2D6 alleles in depressed patients referred to a tertiary psychiatric hospital
    • G. Ruaño, D. Villagra, U.S. Rahim, A. Windemuth, M. Kocherla, and B. Bower Increased carrier prevalence of deficient CYP2C9, CYP2C19 and CYP2D6 alleles in depressed patients referred to a tertiary psychiatric hospital Per Med 5 2008 579 587
    • (2008) Per Med , vol.5 , pp. 579-587
    • Ruaño, G.1    Villagra, D.2    Rahim, U.S.3    Windemuth, A.4    Kocherla, M.5    Bower, B.6
  • 22
    • 84878736766 scopus 로고    scopus 로고
    • Length of psychiatric hospitalization is correlated with CYP2D6 functional status in inpatients with major depressive disorder
    • G. Ruaño, B.L. Szarek, D. Villagra, K. Gorowski, M. Kocherla, and R.L. Seip Length of psychiatric hospitalization is correlated with CYP2D6 functional status in inpatients with major depressive disorder Biomark Med 7 2013 429 439
    • (2013) Biomark Med , vol.7 , pp. 429-439
    • Ruaño, G.1    Szarek, B.L.2    Villagra, D.3    Gorowski, K.4    Kocherla, M.5    Seip, R.L.6
  • 23
    • 10544248170 scopus 로고    scopus 로고
    • The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: Screening costs and influence on clinical outcomes in psychiatry
    • S. Chen, W.H. Chou, R.A. Blouin, Z. Mao, L.L. Humphries, and Q.C. Meek The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: Screening costs and influence on clinical outcomes in psychiatry Clin Pharmacol Ther 60 1996 522 534
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 522-534
    • Chen, S.1    Chou, W.H.2    Blouin, R.A.3    Mao, Z.4    Humphries, L.L.5    Meek, Q.C.6
  • 24
    • 0001697297 scopus 로고    scopus 로고
    • Extension of a pilot study: Impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness
    • W.H. Chou, F.X. Yan, L.J. de, J. Barnhill, T. Rogers, and M. Cronin Extension of a pilot study: Impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness J Clin Psychopharmacol 20 2000 246 251
    • (2000) J Clin Psychopharmacol , vol.20 , pp. 246-251
    • Chou, W.H.1    Yan, F.X.2    De, L.J.3    Barnhill, J.4    Rogers, T.5    Cronin, M.6
  • 26
    • 84861456823 scopus 로고    scopus 로고
    • Intuitive pharmacogenetics: Spontaneous risperidone dosage is related to CYP2D6, CYP3A5 and ABCB1 genotypes
    • S. Mas, P. Gasso, S. Alvarez, E. Parellada, M. Bernardo, and A. Lafuente Intuitive pharmacogenetics: Spontaneous risperidone dosage is related to CYP2D6, CYP3A5 and ABCB1 genotypes Pharmacogenomics J 12 2012 255 259
    • (2012) Pharmacogenomics J , vol.12 , pp. 255-259
    • Mas, S.1    Gasso, P.2    Alvarez, S.3    Parellada, E.4    Bernardo, M.5    Lafuente, A.6
  • 27
    • 0038130873 scopus 로고    scopus 로고
    • Polymorphic drug metabolism (CYP2D6) and utilisation of psychotropic drugs in hospitalised psychiatric patients: A retrospective study
    • W.J. Tamminga, J. Wemer, B. Oosterhuis, B.A. de, S. Vranckx, and B.F. Drenth Polymorphic drug metabolism (CYP2D6) and utilisation of psychotropic drugs in hospitalised psychiatric patients: A retrospective study Eur J Clin Pharmacol 59 2003 57 64
    • (2003) Eur J Clin Pharmacol , vol.59 , pp. 57-64
    • Tamminga, W.J.1    Wemer, J.2    Oosterhuis, B.3    De, B.A.4    Vranckx, S.5    Drenth, B.F.6
  • 28
    • 45549103890 scopus 로고    scopus 로고
    • Psychiatrists' attitudes regarding genetic testing and patient safeguards: A preliminary study
    • J.G. Hoop, L.W. Roberts, K.A. Green Hammond, and N.J. Cox Psychiatrists' attitudes regarding genetic testing and patient safeguards: A preliminary study Genet Test 12 2008 245 252
    • (2008) Genet Test , vol.12 , pp. 245-252
    • Hoop, J.G.1    Roberts, L.W.2    Green Hammond, K.A.3    Cox, N.J.4
  • 29
    • 77953805956 scopus 로고    scopus 로고
    • Clinical and ethical considerations in pharmacogenetic testing: Views of physicians in 3 "early adopting" departments of psychiatry
    • J.G. Hoop, M.I. Lapid, R.M. Paulson, and L.W. Roberts Clinical and ethical considerations in pharmacogenetic testing: Views of physicians in 3 "early adopting" departments of psychiatry J Clin Psychiatry 71 2010 745 753
    • (2010) J Clin Psychiatry , vol.71 , pp. 745-753
    • Hoop, J.G.1    Lapid, M.I.2    Paulson, R.M.3    Roberts, L.W.4
  • 31
    • 69949184308 scopus 로고    scopus 로고
    • A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    • M. Ising, S. Lucae, E.B. Binder, T. Bettecken, M. Uhr, and S. Ripke A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression Arch Gen Psychiatry 66 2009 966 975
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 966-975
    • Ising, M.1    Lucae, S.2    Binder, E.B.3    Bettecken, T.4    Uhr, M.5    Ripke, S.6
  • 33
    • 77951779878 scopus 로고    scopus 로고
    • Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    • R. Uher, N. Perroud, M.Y.M. Ng, J. Hauser, N. Henigsberg, and W. Maier Genome-wide pharmacogenetics of antidepressant response in the GENDEP project Am J Psychiatry 167 2010 555 564
    • (2010) Am J Psychiatry , vol.167 , pp. 555-564
    • Uher, R.1    Perroud, N.2    Ng, M.Y.M.3    Hauser, J.4    Henigsberg, N.5    Maier, W.6
  • 34
    • 84881174811 scopus 로고    scopus 로고
    • Possible association of CUX1 gene polymorphisms with antidepressant response in major depressive disorder
    • D. Sasayama, A. Hiraishi, M. Tatsumi, K. Kamijima, M. Ikeda, and W. Umene-Nakano Possible association of CUX1 gene polymorphisms with antidepressant response in major depressive disorder Pharmacogenomics J 13 2013 354 358
    • (2013) Pharmacogenomics J , vol.13 , pp. 354-358
    • Sasayama, D.1    Hiraishi, A.2    Tatsumi, M.3    Kamijima, K.4    Ikeda, M.5    Umene-Nakano, W.6
  • 35
    • 84884592615 scopus 로고    scopus 로고
    • Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: Genome-wide associations and functional genomics
    • Y. Ji, J.M. Biernacka, S. Hebbring, Y. Chai, G.D. Jenkins, and A. Batzler Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: Genome-wide associations and functional genomics Pharmacogenomics J 13 2013 456 463
    • (2013) Pharmacogenomics J , vol.13 , pp. 456-463
    • Ji, Y.1    Biernacka, J.M.2    Hebbring, S.3    Chai, Y.4    Jenkins, G.D.5    Batzler, A.6
  • 36
    • 79961126893 scopus 로고    scopus 로고
    • Genome-wide association studies of antidepressant outcome: A brief review
    • G. Laje, and F.J. McMahon Genome-wide association studies of antidepressant outcome: A brief review Prog Neuropsychopharmacol Biol Psychiatry 35 2011 1553 1557
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry , vol.35 , pp. 1553-1557
    • Laje, G.1    McMahon, F.J.2
  • 37
    • 84873348443 scopus 로고    scopus 로고
    • Common genetic variation and antidepressant efficacy in major depressive disorder: A meta-analysis of three genome-wide pharmacogenetic studies
    • GENDEP Investigators, MARS Investigators, and STAR∗D Investigators
    • GENDEP Investigators, MARS Investigators, and STAR∗D Investigators Common genetic variation and antidepressant efficacy in major depressive disorder: A meta-analysis of three genome-wide pharmacogenetic studies Am J Psychiatry 170 2013 207 217
    • (2013) Am J Psychiatry , vol.170 , pp. 207-217
  • 38
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: The emerging picture and its implications
    • P.F. Sullivan, M.J. Daly, and M. O'Donovan Genetic architectures of psychiatric disorders: The emerging picture and its implications Nat Rev Genet 13 2012 537 551
    • (2012) Nat Rev Genet , vol.13 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O'Donovan, M.3
  • 39
    • 37349093041 scopus 로고    scopus 로고
    • Recommendations from the EGAPP Working Group: Testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors
    • EGAPP
    • EGAPP Recommendations from the EGAPP Working Group: Testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors Genet Med 9 2007 819 825
    • (2007) Genet Med , vol.9 , pp. 819-825
  • 43
    • 84885082776 scopus 로고    scopus 로고
    • Utility of integrated pharmacogenomic testing to support the treatment of major depressive disorder in a psychiatric outpatient setting
    • D.K. Hall-Flavin, J.G. Winner, J.D. Allen, J.M. Carhart, B. Proctor, and K.A. Snyder Utility of integrated pharmacogenomic testing to support the treatment of major depressive disorder in a psychiatric outpatient setting Pharmacogenet Genomics 23 2013 535 548
    • (2013) Pharmacogenet Genomics , vol.23 , pp. 535-548
    • Hall-Flavin, D.K.1    Winner, J.G.2    Allen, J.D.3    Carhart, J.M.4    Proctor, B.5    Snyder, K.A.6
  • 45
    • 67651174493 scopus 로고    scopus 로고
    • Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study
    • C. Lavedan, L. Licamele, S. Volpi, J. Hamilton, C. Heaton, and K. Mack Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study Mol Psychiatry 14 2009 804 819
    • (2009) Mol Psychiatry , vol.14 , pp. 804-819
    • Lavedan, C.1    Licamele, L.2    Volpi, S.3    Hamilton, J.4    Heaton, C.5    Mack, K.6
  • 46
    • 66949165513 scopus 로고    scopus 로고
    • A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder
    • R.H. Perlis, J.W. Smoller, M.A. Ferreira, A. McQuillin, N. Bass, and J. Lawrence A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder Am J Psychiatry 166 2009 718 725
    • (2009) Am J Psychiatry , vol.166 , pp. 718-725
    • Perlis, R.H.1    Smoller, J.W.2    Ferreira, M.A.3    McQuillin, A.4    Bass, N.5    Lawrence, J.6
  • 47
    • 84879219224 scopus 로고    scopus 로고
    • Assessment of response to lithium maintenance treatment in bipolar disorder: A Consortium on Lithium Genetics (ConLiGen) report
    • M. Manchia, M. Adli, N. Akula, R. Ardau, J.M. Aubry, and L. Backlund Assessment of response to lithium maintenance treatment in bipolar disorder: A Consortium on Lithium Genetics (ConLiGen) report PLoS One 8 2013 e65636
    • (2013) PLoS One , vol.8 , pp. e65636
    • Manchia, M.1    Adli, M.2    Akula, N.3    Ardau, R.4    Aubry, J.M.5    Backlund, L.6
  • 48
    • 70249083016 scopus 로고    scopus 로고
    • Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients
    • G. Laje, A.S. Allen, N. Akula, H. Manji, R.A. John, and F.J. McMahon Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients Pharmacogenet Genomics 19 2009 666 674
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 666-674
    • Laje, G.1    Allen, A.S.2    Akula, N.3    Manji, H.4    John, R.A.5    McMahon, F.J.6
  • 49
    • 79959981469 scopus 로고    scopus 로고
    • Genomewide association scan of suicidal thoughts and behaviour in major depression
    • A. Schosser, A.W. Butler, M. Ising, N. Perroud, R. Uher, and M.Y. Ng Genomewide association scan of suicidal thoughts and behaviour in major depression PLoS One 6 2011 e20690
    • (2011) PLoS One , vol.6 , pp. e20690
    • Schosser, A.1    Butler, A.W.2    Ising, M.3    Perroud, N.4    Uher, R.5    Ng, M.Y.6
  • 50
    • 84856164097 scopus 로고    scopus 로고
    • Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project
    • N. Perroud, R. Uher, M.Y.M. Ng, M. Guipponi, J. Hauser, and N. Henigsberg Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project Pharmacogenomics J 12 2012 68 77
    • (2012) Pharmacogenomics J , vol.12 , pp. 68-77
    • Perroud, N.1    Uher, R.2    Ng, M.Y.M.3    Guipponi, M.4    Hauser, J.5    Henigsberg, N.6
  • 51
    • 79951813616 scopus 로고    scopus 로고
    • Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs
    • D.E. Adkins, K. Aberg, J.L. McClay, J. Bukszar, Z. Zhao, and P. Jia Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs Mol Psychiatry 16 2011 321 332
    • (2011) Mol Psychiatry , vol.16 , pp. 321-332
    • Adkins, D.E.1    Aberg, K.2    McClay, J.L.3    Bukszar, J.4    Zhao, Z.5    Jia, P.6
  • 52
    • 84858999530 scopus 로고    scopus 로고
    • Genome-wide association study of antipsychotic-induced QTc interval prolongation
    • K. Åberg, D.E. Adkins, Y. Liu, J.L. McClay, J. Bukszar, and P. Jia Genome-wide association study of antipsychotic-induced QTc interval prolongation Pharmacogenomics J 12 2012 165 172
    • (2012) Pharmacogenomics J , vol.12 , pp. 165-172
    • Åberg, K.1    Adkins, D.E.2    Liu, Y.3    McClay, J.L.4    Bukszar, J.5    Jia, P.6
  • 53
    • 70350574270 scopus 로고    scopus 로고
    • Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia
    • S. Volpi, C. Heaton, K. Mack, J.B. Hamilton, R. Lannan, and C.D. Wolfgang Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia Mol Psychiatry 14 2008 1024 1031
    • (2008) Mol Psychiatry , vol.14 , pp. 1024-1031
    • Volpi, S.1    Heaton, C.2    Mack, K.3    Hamilton, J.B.4    Lannan, R.5    Wolfgang, C.D.6
  • 55
    • 70349574008 scopus 로고    scopus 로고
    • Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients
    • A. Alkelai, L. Greenbaum, A. Rigbi, K. Kanyas, and B. Lerer Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients Psychopharmacology 206 2009 491 499
    • (2009) Psychopharmacology , vol.206 , pp. 491-499
    • Alkelai, A.1    Greenbaum, L.2    Rigbi, A.3    Kanyas, K.4    Lerer, B.5
  • 57
    • 79953216429 scopus 로고    scopus 로고
    • Carbamazepine-induced toxic effects and HLA-B∗1502 screening in Taiwan
    • P. Chen, J.J. Lin, C.S. Lu, C.T. Ong, P.F. Hsieh, and C.C. Yang Carbamazepine-induced toxic effects and HLA-B∗1502 screening in Taiwan N Engl J Med 364 2011 1126 1133
    • (2011) N Engl J Med , vol.364 , pp. 1126-1133
    • Chen, P.1    Lin, J.J.2    Lu, C.S.3    Ong, C.T.4    Hsieh, P.F.5    Yang, C.C.6
  • 58
    • 79551600984 scopus 로고    scopus 로고
    • Genome-wide association study identifies HLA-A∗3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population
    • T. Ozeki, T. Mushiroda, A. Yowang, A. Takahashi, M. Kubo, and Y. Shirakata Genome-wide association study identifies HLA-A∗3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population Hum Mol Genet 20 2011 1034 1041
    • (2011) Hum Mol Genet , vol.20 , pp. 1034-1041
    • Ozeki, T.1    Mushiroda, T.2    Yowang, A.3    Takahashi, A.4    Kubo, M.5    Shirakata, Y.6
  • 60
    • 84865975078 scopus 로고    scopus 로고
    • Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain
    • A.K. Malhotra, C.U. Correll, N.I. Chowdhury, D.J. Muller, P.K. Gregersen, and A.T. Lee Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain Arch Gen Psychiatry 69 2012 904 912
    • (2012) Arch Gen Psychiatry , vol.69 , pp. 904-912
    • Malhotra, A.K.1    Correll, C.U.2    Chowdhury, N.I.3    Muller, D.J.4    Gregersen, P.K.5    Lee, A.T.6
  • 61
    • 33646404622 scopus 로고    scopus 로고
    • Melanocortin 4 receptor mutations in a large cohort of severely obese adults: Prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating
    • C. Lubrano-Berthelier, B. Dubern, J.M. Lacorte, F. Picard, A. Shapiro, and S. Zhang Melanocortin 4 receptor mutations in a large cohort of severely obese adults: Prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating J Clin Endocrinol Metab 91 2006 1811 1818
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1811-1818
    • Lubrano-Berthelier, C.1    Dubern, B.2    Lacorte, J.M.3    Picard, F.4    Shapiro, A.5    Zhang, S.6
  • 62
    • 58149163142 scopus 로고    scopus 로고
    • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
    • C.J. Willer, E.K. Speliotes, R.J. Loos, S. Li, C.M. Lindgren, and I.M. Heid Six new loci associated with body mass index highlight a neuronal influence on body weight regulation Nat Genet 41 2009 25 34
    • (2009) Nat Genet , vol.41 , pp. 25-34
    • Willer, C.J.1    Speliotes, E.K.2    Loos, R.J.3    Li, S.4    Lindgren, C.M.5    Heid, I.M.6
  • 63
    • 84879952310 scopus 로고    scopus 로고
    • Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies
    • E.L. Nurmi, S.L. Spilman, F. Whelan, L.L. Scahill, M.G. Aman, and C.J. McDougle Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies Transl Psychiatry 3 2013 e274
    • (2013) Transl Psychiatry , vol.3 , pp. e274
    • Nurmi, E.L.1    Spilman, S.L.2    Whelan, F.3    Scahill, L.L.4    Aman, M.G.5    McDougle, C.J.6
  • 64
    • 84883355708 scopus 로고    scopus 로고
    • MC4R rs489693: A clinical risk factor for second generation antipsychotic-related weight gain?
    • F. Czerwensky, S. Leucht, and W. Steimer MC4R rs489693: A clinical risk factor for second generation antipsychotic-related weight gain? Int J Neuropsychopharmacol 16 2013 2103 2109
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 2103-2109
    • Czerwensky, F.1    Leucht, S.2    Steimer, W.3
  • 65
    • 17644423416 scopus 로고    scopus 로고
    • CYP2D6 polymorphisms and the risk of tardive dyskinesia in schizophrenia: A meta-analysis
    • N.A. Patsopoulos, E.E. Ntzani, E. Zintzaras, and J.P. Ioannidis CYP2D6 polymorphisms and the risk of tardive dyskinesia in schizophrenia: A meta-analysis Pharmacogenet Genomics 15 2005 151 158
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 151-158
    • Patsopoulos, N.A.1    Ntzani, E.E.2    Zintzaras, E.3    Ioannidis, J.P.4
  • 66
    • 79955508661 scopus 로고    scopus 로고
    • Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine-induced agranulocytosis
    • M.C. Athanasiou, M. Dettling, I. Cascorbi, I. Mosyagin, B.A. Salisbury, and K.A. Pierz Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine-induced agranulocytosis J Clin Psychiatry 72 2011 458 463
    • (2011) J Clin Psychiatry , vol.72 , pp. 458-463
    • Athanasiou, M.C.1    Dettling, M.2    Cascorbi, I.3    Mosyagin, I.4    Salisbury, B.A.5    Pierz, K.A.6
  • 67
    • 77955061641 scopus 로고    scopus 로고
    • Pharmacogenetics and human genetic polymorphisms
    • A.K. Daly Pharmacogenetics and human genetic polymorphisms Biochem J 429 2010 435 449
    • (2010) Biochem J , vol.429 , pp. 435-449
    • Daly, A.K.1
  • 68
    • 84876529436 scopus 로고    scopus 로고
    • Clinical implementation of pharmacogenetics: More than one gene at a time
    • J.A. Johnson, T.E. Klein, and M.V. Relling Clinical implementation of pharmacogenetics: More than one gene at a time Clin Pharmacol Ther 93 2013 384 385
    • (2013) Clin Pharmacol Ther , vol.93 , pp. 384-385
    • Johnson, J.A.1    Klein, T.E.2    Relling, M.V.3
  • 69
    • 84870065029 scopus 로고    scopus 로고
    • VeriStrat has prognostic value in advanced stage NSCLC patients treated with erlotinib and sorafenib
    • J.L. Kuiper, J.S. Lind, H.J. Groen, J. Roder, J. Grigorieva, and H. Roder VeriStrat has prognostic value in advanced stage NSCLC patients treated with erlotinib and sorafenib Br J Cancer 107 2012 1820 1825
    • (2012) Br J Cancer , vol.107 , pp. 1820-1825
    • Kuiper, J.L.1    Lind, J.S.2    Groen, H.J.3    Roder, J.4    Grigorieva, J.5    Roder, H.6
  • 70
    • 82755181967 scopus 로고    scopus 로고
    • Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action
    • J. Xuan, G. Pan, Y. Qiu, L. Yang, M. Su, and Y. Liu Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action J Proteome Res 10 2011 5433 5443
    • (2011) J Proteome Res , vol.10 , pp. 5433-5443
    • Xuan, J.1    Pan, G.2    Qiu, Y.3    Yang, L.4    Su, M.5    Liu, Y.6
  • 71
    • 40949152450 scopus 로고    scopus 로고
    • Pharmacogenetic studies in depression: A proposal for methodologic guidelines
    • A. Serretti, M. Kato, and J.L. Kennedy Pharmacogenetic studies in depression: A proposal for methodologic guidelines Pharmacogenomics J 8 2008 90 100
    • (2008) Pharmacogenomics J , vol.8 , pp. 90-100
    • Serretti, A.1    Kato, M.2    Kennedy, J.L.3
  • 74
    • 60849115571 scopus 로고    scopus 로고
    • Pharmacogenetics - Tailoring treatment for the outliers
    • J. Woodcock, and L.J. Lesko Pharmacogenetics - tailoring treatment for the outliers N Engl J Med 360 2009 811 813
    • (2009) N Engl J Med , vol.360 , pp. 811-813
    • Woodcock, J.1    Lesko, L.J.2
  • 75
    • 84879321551 scopus 로고    scopus 로고
    • A Clinical risk stratification tool for predicting treatment resistance in major depressive disorder
    • R.H. Perlis A Clinical risk stratification tool for predicting treatment resistance in major depressive disorder Biol Psychiatry 74 2013 7 14
    • (2013) Biol Psychiatry , vol.74 , pp. 7-14
    • Perlis, R.H.1
  • 76
    • 84877645710 scopus 로고    scopus 로고
    • Pharmacogenetics in clinical practice: How far have we come and where are we going?
    • J.A. Johnson Pharmacogenetics in clinical practice: How far have we come and where are we going? Pharmacogenomics 14 2013 835 843
    • (2013) Pharmacogenomics , vol.14 , pp. 835-843
    • Johnson, J.A.1
  • 77
    • 67651166984 scopus 로고    scopus 로고
    • Implementation of pharmacogenomics into the clinical practice of therapeutics: Issues for the clinician and the laboratorian
    • A.H. Wu, N. Babic, and K.T. Yeo Implementation of pharmacogenomics into the clinical practice of therapeutics: Issues for the clinician and the laboratorian Per Med 6 2009 315 327
    • (2009) Per Med , vol.6 , pp. 315-327
    • Wu, A.H.1    Babic, N.2    Yeo, K.T.3
  • 78
    • 79951809825 scopus 로고    scopus 로고
    • CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network
    • M.V. Relling, and T.E. Klein CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network Clin Pharmacol Ther 89 2011 464 467
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 464-467
    • Relling, M.V.1    Klein, T.E.2
  • 81
    • 77957172283 scopus 로고    scopus 로고
    • Pharmacogenomics instruction in US and Canadian medical schools: Implications for personalized medicine
    • J.S. Green, T.J. O'Brien, V.A. Chiappinelli, and A.F. Harralson Pharmacogenomics instruction in US and Canadian medical schools: Implications for personalized medicine Pharmacogenomics 11 2010 1331 1340
    • (2010) Pharmacogenomics , vol.11 , pp. 1331-1340
    • Green, J.S.1    O'Brien, T.J.2    Chiappinelli, V.A.3    Harralson, A.F.4
  • 82
    • 84858422325 scopus 로고    scopus 로고
    • Translation of pharmacogenetics to clinical practice: What will it take?
    • R.L. Slaughter Translation of pharmacogenetics to clinical practice: What will it take? Expert Rev Clin Pharmacol 5 2012 101 103
    • (2012) Expert Rev Clin Pharmacol , vol.5 , pp. 101-103
    • Slaughter, R.L.1
  • 83
    • 79959938418 scopus 로고    scopus 로고
    • Electronic medical records and personalized medicine
    • M.A. Hoffman, and M.S. Williams Electronic medical records and personalized medicine Hum Genet 130 2011 33 39
    • (2011) Hum Genet , vol.130 , pp. 33-39
    • Hoffman, M.A.1    Williams, M.S.2
  • 84
    • 84861344364 scopus 로고    scopus 로고
    • Electronic medical records as a tool in clinical pharmacology: Opportunities and challenges
    • D.M. Roden, H. Xu, J.C. Denny, and R.A. Wilke Electronic medical records as a tool in clinical pharmacology: Opportunities and challenges Clin Pharmacol Ther 91 2012 1083 1086
    • (2012) Clin Pharmacol Ther , vol.91 , pp. 1083-1086
    • Roden, D.M.1    Xu, H.2    Denny, J.C.3    Wilke, R.A.4
  • 85
    • 84866595897 scopus 로고    scopus 로고
    • The 1200 patients project: Creating a new medical model system for clinical implementation of pharmacogenomics
    • P.H. O'Donnell, A. Bush, J. Spitz, K. Danahey, D. Saner, and S. Das The 1200 patients project: Creating a new medical model system for clinical implementation of pharmacogenomics Clin Pharmacol Ther 92 2012 446 449
    • (2012) Clin Pharmacol Ther , vol.92 , pp. 446-449
    • O'Donnell, P.H.1    Bush, A.2    Spitz, J.3    Danahey, K.4    Saner, D.5    Das, S.6
  • 86
    • 84867848963 scopus 로고    scopus 로고
    • A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record
    • J.K. Hicks, K.R. Crews, J.M. Hoffman, N.M. Kornegay, M.R. Wilkinson, and R. Lorier A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record Clin Pharmacol Ther 92 2012 563 566
    • (2012) Clin Pharmacol Ther , vol.92 , pp. 563-566
    • Hicks, J.K.1    Crews, K.R.2    Hoffman, J.M.3    Kornegay, N.M.4    Wilkinson, M.R.5    Lorier, R.6
  • 87
    • 84862620703 scopus 로고    scopus 로고
    • Operational implementation of prospective genotyping for personalized medicine: The Design of the Vanderbilt PREDICT Project
    • J.M. Pulley, J.C. Denny, J.F. Peterson, G.R. Bernard, C.L. Vnencak-Jones, and A.H. Ramirez Operational implementation of prospective genotyping for personalized medicine: The Design of the Vanderbilt PREDICT Project Clin Pharmacol Ther 92 2012 87 95
    • (2012) Clin Pharmacol Ther , vol.92 , pp. 87-95
    • Pulley, J.M.1    Denny, J.C.2    Peterson, J.F.3    Bernard, G.R.4    Vnencak-Jones, C.L.5    Ramirez, A.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.