메뉴 건너뛰기




Volumn 5, Issue 6, 2008, Pages 579-587

Increased carrier prevalence of deficient CYP2C9, CYP2C19 and CYP2D6 alleles in depressed patients referred to a tertiary psychiatric hospital

Author keywords

Alleles; CYP2C19; CYP2C9; CYP2D6; Drug metabolism; Patient safety; Pharmacogenetics; Psychotropic drug safety

Indexed keywords

AMFEBUTAMONE; ARIPIPRAZOLE; CLONAZEPAM; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; FLUOXETINE; LAMOTRIGINE; METHYLPHENIDATE; OXCARBAZEPINE; PAROXETINE; QUETIAPINE; RISPERIDONE; SERTRALINE; TOPIRAMATE; VALPROIC ACID; VENLAFAXINE;

EID: 57749177273     PISSN: 17410541     EISSN: 1744828X     Source Type: Journal    
DOI: 10.2217/17410541.5.6.579     Document Type: Article
Times cited : (9)

References (33)
  • 1
    • 0031001720 scopus 로고    scopus 로고
    • Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
    • Murray CJ, Lopez AD: Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 349, 1498-1504 (1997).
    • (1997) Lancet , vol.349 , pp. 1498-1504
    • Murray, C.J.1    Lopez, A.D.2
  • 2
    • 29544449443 scopus 로고    scopus 로고
    • Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19
    • de Leon J, Armstrong SC, Cozza KL: Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19. Psychosomatics 47, 75-85 (2006).
    • (2006) Psychosomatics , vol.47 , pp. 75-85
    • de Leon, J.1    Armstrong, S.C.2    Cozza, K.L.3
  • 3
    • 33646807029 scopus 로고    scopus 로고
    • Clinical implementation of psychiatric pharmacogenomic testing
    • Mrazek DA: Clinical implementation of psychiatric pharmacogenomic testing. Pers. Med. 2, 93-95 (2005).
    • (2005) Pers. Med , vol.2 , pp. 93-95
    • Mrazek, D.A.1
  • 4
    • 34548395024 scopus 로고    scopus 로고
    • Incorporating pharmacogenetics into clinical practice: Reality of a new tool in psychiatry. The context of genetic testing in clinical psychiatric practice
    • Mrazek DA: Incorporating pharmacogenetics into clinical practice: reality of a new tool in psychiatry. The context of genetic testing in clinical psychiatric practice. CNS. Spear. 11, 3-4 (2006).
    • (2006) CNS. Spear , vol.11 , pp. 3-4
    • Mrazek, D.A.1
  • 6
    • 3142519666 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response
    • Kirchheiner J, Nickchen K, Bauer M et al.: Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response. Mol. Psychiatry 9, 442-473 (2004).
    • (2004) Mol. Psychiatry , vol.9 , pp. 442-473
    • Kirchheiner, J.1    Nickchen, K.2    Bauer, M.3
  • 8
    • 34249331703 scopus 로고    scopus 로고
    • Somatic complications of psychotropic medications in a patient with multiple CYP2 drug metabolism deficiencies
    • Ruaño G, Blair CL, Bower B et al.: Somatic complications of psychotropic medications in a patient with multiple CYP2 drug metabolism deficiencies. Conn. Med. 71, 197-200 (2007).
    • (2007) Conn. Med , vol.71 , pp. 197-200
    • Ruaño, G.1    Blair, C.L.2    Bower, B.3
  • 9
    • 13544249943 scopus 로고    scopus 로고
    • Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity
    • Ingelman-Sundberg M: Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics. J. 5, 6-13 (2005).
    • (2005) Pharmacogenomics. J , vol.5 , pp. 6-13
    • Ingelman-Sundberg, M.1
  • 10
    • 2042437099 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 and antidepressant toxicity and response: What is the evidence?
    • Wedlund PJ, de Leon J: Cytochrome P450 2D6 and antidepressant toxicity and response: what is the evidence? Clin. Pharmacol. Ther. 75, 373-375 (2004).
    • (2004) Clin. Pharmacol. Ther , vol.75 , pp. 373-375
    • Wedlund, P.J.1    de Leon, J.2
  • 11
    • 0027464041 scopus 로고
    • Relationship between personality and debrisoquine hydroxylation capacity. Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6
    • LLerena A, Edman G, Cobaleda J, Benitez J, Schalling D, Bertilsson L: Relationship between personality and debrisoquine hydroxylation capacity. Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6. Acta Psychiatr. Scand. 87, 23-28 (1993).
    • (1993) Acta Psychiatr. Scand , vol.87 , pp. 23-28
    • LLerena, A.1    Edman, G.2    Cobaleda, J.3    Benitez, J.4    Schalling, D.5    Bertilsson, L.6
  • 13
    • 33847031732 scopus 로고    scopus 로고
    • CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure
    • Sistonen J, Sajantila A, Lao O, Corander J, Barbujani G, Fuselli S: CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure. Pharmacogenet. Genomics 17, 93-101 (2007).
    • (2007) Pharmacogenet. Genomics , vol.17 , pp. 93-101
    • Sistonen, J.1    Sajantila, A.2    Lao, O.3    Corander, J.4    Barbujani, G.5    Fuselli, S.6
  • 14
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford LD: CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 3, 229-243 (2002).
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1
  • 15
    • 0036073564 scopus 로고    scopus 로고
    • Cytochrome p450 phenotyping/genotyping in patients receiving antipsychotics: Useful aid to prescribing?
    • Dahl ML: Cytochrome p450 phenotyping/genotyping in patients receiving antipsychotics: useful aid to prescribing? Clin. Pharmacokinet. 41, 453-470 (2002).
    • (2002) Clin. Pharmacokinet , vol.41 , pp. 453-470
    • Dahl, M.L.1
  • 17
    • 34147150577 scopus 로고    scopus 로고
    • A clinical study of the association of antipsychotics with hyperlipidemia
    • de Leon J, Susce MT, Johnson M et al.: A clinical study of the association of antipsychotics with hyperlipidemia. Schizophr. Res. 92, 95-102 (2007).
    • (2007) Schizophr. Res , vol.92 , pp. 95-102
    • de Leon, J.1    Susce, M.T.2    Johnson, M.3
  • 18
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
    • Lazarou J, Pomeranz BH, Corey PN: Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 279, 1200-1205 (1998).
    • (1998) JAMA , vol.279 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 19
    • 0037420274 scopus 로고    scopus 로고
    • Incidence and preventability of adverse drug events among older persons in the ambulatory setting
    • Gurwitz JH, Field TS, Harrold LR et al.: Incidence and preventability of adverse drug events among older persons in the ambulatory setting. JAMA 289, 1107-1116 (2003).
    • (2003) JAMA , vol.289 , pp. 1107-1116
    • Gurwitz, J.H.1    Field, T.S.2    Harrold, L.R.3
  • 20
    • 0037421584 scopus 로고    scopus 로고
    • Inheritance and drug response
    • Weinshilboum R: Inheritance and drug response. N. Engl. J. Med. 348, 529-537 (2003).
    • (2003) N. Engl. J. Med , vol.348 , pp. 529-537
    • Weinshilboum, R.1
  • 21
    • 0035291754 scopus 로고    scopus 로고
    • Drug-related morbidity and mortality: Updating the cost-of-illness model
    • Ernst FR, Grizzle AJ: Drug-related morbidity and mortality: updating the cost-of-illness model. J. Am. Pharm. Assoc. (Wash.) 41, 192-199 (2001).
    • (2001) J. Am. Pharm. Assoc. (Wash.) , vol.41 , pp. 192-199
    • Ernst, F.R.1    Grizzle, A.J.2
  • 23
    • 28444490336 scopus 로고    scopus 로고
    • Physiogenomic analysis links serum creatine kinase activities during statin therapy to vascular smooth muscle homeostasis
    • Ruaño G, Thompson PD, Windemuth A et al.: Physiogenomic analysis links serum creatine kinase activities during statin therapy to vascular smooth muscle homeostasis. Pharmacogenomics 6, 865-872 (2005).
    • (2005) Pharmacogenomics , vol.6 , pp. 865-872
    • Ruaño, G.1    Thompson, P.D.2    Windemuth, A.3
  • 24
    • 33646812979 scopus 로고    scopus 로고
    • High carrier prevalence of deficient and null alleles of CYP2 genes in a major USA hospital: Implications for personalized drug safety
    • Ruaño G, Makowski G, Windemuth A et al.: High carrier prevalence of deficient and null alleles of CYP2 genes in a major USA hospital: implications for personalized drug safety. Pers. Med. 3, 131-137 (2006).
    • (2006) Pers. Med , vol.3 , pp. 131-137
    • Ruaño, G.1    Makowski, G.2    Windemuth, A.3
  • 25
    • 33845439872 scopus 로고    scopus 로고
    • Determination of CYP2D6, CYP2C9 and CYP2C19 genotypes with Tag-It mutation detection assays
    • Melis R, Lyon E, McMillin GA: Determination of CYP2D6, CYP2C9 and CYP2C19 genotypes with Tag-It mutation detection assays. Expert Rev. Mol. Diagn. 6, 811-820 (2006).
    • (2006) Expert Rev. Mol. Diagn , vol.6 , pp. 811-820
    • Melis, R.1    Lyon, E.2    McMillin, G.A.3
  • 28
    • 0035293495 scopus 로고    scopus 로고
    • Cytochrome P450 isoforms involved in melatonin metabolism in human liver microsomes
    • Facciola G, Hidestrand M, von Bahr C, Tybring G: Cytochrome P450 isoforms involved in melatonin metabolism in human liver microsomes. Eur. J. Clin. Pharmacol. 56, 881-888 (2001).
    • (2001) Eur. J. Clin. Pharmacol , vol.56 , pp. 881-888
    • Facciola, G.1    Hidestrand, M.2    von Bahr, C.3    Tybring, G.4
  • 29
    • 20644448824 scopus 로고    scopus 로고
    • Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage
    • Wilke RA, Moore JH, Burmester JK: Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage. Pharmacogenet. Genomics 15, 415-421 (2005).
    • (2005) Pharmacogenet. Genomics , vol.15 , pp. 415-421
    • Wilke, R.A.1    Moore, J.H.2    Burmester, J.K.3
  • 30
    • 33746102723 scopus 로고    scopus 로고
    • CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: Implications for clinical practice and genetic testing
    • Cai WM, Nikoloff DM, Pan RM et al.: CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: implications for clinical practice and genetic testing. Pharmacogenomics. J. 6, 343-350 (2006).
    • (2006) Pharmacogenomics. J , vol.6 , pp. 343-350
    • Cai, W.M.1    Nikoloff, D.M.2    Pan, R.M.3
  • 31
    • 34548103768 scopus 로고    scopus 로고
    • CYP2C9, CYP2C19 and CYP2D6 allele frequencies in the Ashkenazi Jewish population
    • Scott SA, Edelmann L, Kornreich R, Erazo M, Desnick RJ: CYP2C9, CYP2C19 and CYP2D6 allele frequencies in the Ashkenazi Jewish population. Pharmacogenomics 8, 721-730 (2007).
    • (2007) Pharmacogenomics , vol.8 , pp. 721-730
    • Scott, S.A.1    Edelmann, L.2    Kornreich, R.3    Erazo, M.4    Desnick, R.J.5
  • 32
    • 37349093041 scopus 로고    scopus 로고
    • testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors
    • Recommendations from the EGAPP Working Group
    • Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors. Genet. Med. 9, 819-825 (2007).
    • (2007) Genet. Med , vol.9 , pp. 819-825
  • 33
    • 28844491802 scopus 로고    scopus 로고
    • Drug-metabolizing enzymes: Evidence for clinical utility of pharmacogenomic tests
    • Andersson T, Flockhart DA, Goldstein DB et al.: Drug-metabolizing enzymes: evidence for clinical utility of pharmacogenomic tests. Clin. Pharmacol. Ther. 78, 559-581 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.78 , pp. 559-581
    • Andersson, T.1    Flockhart, D.A.2    Goldstein, D.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.