-
1
-
-
0030935086
-
Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
-
Bertz RJ, Granneman GR (1997) Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin Pharmacokinet 32:210-258
-
(1997)
Clin Pharmacokinet
, vol.32
, pp. 210-258
-
-
Bertz, R.J.1
Granneman, G.R.2
-
3
-
-
0030995879
-
Molecular mechanism of genetic polymorphism of drug metabolism
-
Meyer UA, Zanger UM (1997) Molecular mechanism of genetic polymorphism of drug metabolism. Annu Rev Pharmacol Toxicol 37:269-296
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 269-296
-
-
Meyer, U.A.1
Zanger, U.M.2
-
4
-
-
8944256082
-
Nomenclature for human CYP2D6 alleles
-
Daly AK, Brockmöller J, Broly F, Eichelbaum M, Evans WE, Gonzalez FJ, Huang J-D, Idle JR, Ingelman-Sundberg M, Ishizaki T, Jacqz-Aigrain E, Meyer UA, Nebert DW, Steen VM, Wolf CR, Zanger UM (1996) Nomenclature for human CYP2D6 alleles. Pharmacogenetics 6:193-201
-
(1996)
Pharmacogenetics
, vol.6
, pp. 193-201
-
-
Daly, A.K.1
Brockmöller, J.2
Broly, F.3
Eichelbaum, M.4
Evans, W.E.5
Gonzalez, F.J.6
Huang, J.-D.7
Idle, J.R.8
Ingelman-Sundberg, M.9
Ishizaki, T.10
Jacqz-Aigrain, E.11
Meyer, U.A.12
Nebert, D.W.13
Steen, V.M.14
Wolf, C.R.15
Zanger, U.M.16
-
5
-
-
0031884233
-
Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in German population
-
Griese E-U, Zanger UM, Brudermanns U, Gaedigk A, Mikus G, Mörike K, Stüven T, Eichelbaum M (1998) Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in German population. Pharmacogenetics 8:15-26
-
(1998)
Pharmacogenetics
, vol.8
, pp. 15-26
-
-
Griese, E.-U.1
Zanger, U.M.2
Brudermanns, U.3
Gaedigk, A.4
Mikus, G.5
Mörike, K.6
Stüven, T.7
Eichelbaum, M.8
-
6
-
-
0029834060
-
Clinical importance of genetic polymorphism of drug oxidation
-
Edeki T (1996) Clinical importance of genetic polymorphism of drug oxidation. Mount Sinai J Med 63:290-300
-
(1996)
Mount Sinai J Med
, vol.63
, pp. 290-300
-
-
Edeki, T.1
-
7
-
-
0028318740
-
Pharmacogenetic aspects in the metabolism of psychotropic drug: Pharmacokinetics and clinical implications
-
Spina E, Caputi AP (1994) Pharmacogenetic aspects in the metabolism of psychotropic drug: pharmacokinetics and clinical implications. Pharmacol Res 29:121-137
-
(1994)
Pharmacol Res
, vol.29
, pp. 121-137
-
-
Spina, E.1
Caputi, A.P.2
-
8
-
-
9044221758
-
Antidepressant and drug-metabolizing enzymes - Expert group report
-
Meyer UA, Amrein R, Balant LP, Bertilsson L, Eichelbaum M, Guenter TW, Henauer S, Jackson P, Laux G, Mikkelsen H, Peck C, Pollock B, Priest R, Sjöqvist F, Delini-Stula A (1996) Antidepressant and drug-metabolizing enzymes - expert group report. Acta Psychiatr Scand 93:71-79
-
(1996)
Acta Psychiatr Scand
, vol.93
, pp. 71-79
-
-
Meyer, U.A.1
Amrein, R.2
Balant, L.P.3
Bertilsson, L.4
Eichelbaum, M.5
Guenter, T.W.6
Henauer, S.7
Jackson, P.8
Laux, G.9
Mikkelsen, H.10
Peck, C.11
Pollock, B.12
Priest, R.13
Sjöqvist, F.14
Delini-Stula, A.15
-
9
-
-
0031028101
-
Relationship between plasma desipramine levels, CYP2D6 phenotype and clinical response to desipramine: A prospective study
-
Spina E, Gitto C, Avenoso A, Campo GM, Caputi AP, Perucca E (1997) Relationship between plasma desipramine levels, CYP2D6 phenotype and clinical response to desipramine: a prospective study. Eur J Clin Pharmacol 51:395-398
-
(1997)
Eur J Clin Pharmacol
, vol.51
, pp. 395-398
-
-
Spina, E.1
Gitto, C.2
Avenoso, A.3
Campo, G.M.4
Caputi, A.P.5
Perucca, E.6
-
10
-
-
0030476715
-
Clinical implications of antidepressant pharmacokinetics and pharmacogenetics
-
Cohen LJ, DeVane CL (1996) Clinical implications of antidepressant pharmacokinetics and pharmacogenetics Ann Pharmacother 30:1471-1480
-
(1996)
Ann Pharmacother
, vol.30
, pp. 1471-1480
-
-
Cohen, L.J.1
DeVane, C.L.2
-
11
-
-
0027483214
-
Genetically variable metabolism of antidepressants and neuroleptic drug in man
-
Dahl ML, Bertilsson L (1993) Genetically variable metabolism of antidepressants and neuroleptic drug in man. Pharmacogenetics 3:61-70
-
(1993)
Pharmacogenetics
, vol.3
, pp. 61-70
-
-
Dahl, M.L.1
Bertilsson, L.2
-
12
-
-
0024333471
-
Disposition of perphenazine is related to polymorphic debrisoquine hydroxylation in human beings
-
Dahl-Puustinen ML, Lidén A, Alm C, Nordin C, Bertilsson L (1989) Disposition of perphenazine is related to polymorphic debrisoquine hydroxylation in human beings. Clin Pharmacol Ther 46:78-81
-
(1989)
Clin Pharmacol Ther
, vol.46
, pp. 78-81
-
-
Dahl-Puustinen, M.L.1
Lidén, A.2
Alm, C.3
Nordin, C.4
Bertilsson, L.5
-
13
-
-
0029979414
-
Polymorphic drug oxidation: Relevance to the treatment of psychiatric disorders
-
Bertilsson L, Dahl ML (1996) Polymorphic drug oxidation: relevance to the treatment of psychiatric disorders. CNS Drugs 5:200-223
-
(1996)
CNS Drugs
, vol.5
, pp. 200-223
-
-
Bertilsson, L.1
Dahl, M.L.2
-
14
-
-
0032712465
-
Drug extrapyrimidal side effects. CYP2D6 genotypes and phenotypes
-
Vandel P, Haffen E, Vandel S, Bonin B, Nezelhof S, Sechter D, Broly F, Biouard P, Dalery J (1999) Drug extrapyrimidal side effects. CYP2D6 genotypes and phenotypes. Eur J Clin Pharmacol 55:659-665
-
(1999)
Eur J Clin Pharmacol
, vol.55
, pp. 659-665
-
-
Vandel, P.1
Haffen, E.2
Vandel, S.3
Bonin, B.4
Nezelhof, S.5
Sechter, D.6
Broly, F.7
Biouard, P.8
Dalery, J.9
-
15
-
-
10544248170
-
The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: Screening costs and influence on clinical outcomes in psychiatry
-
Chen S, Chou WH, Blouin RA, Mao Z, Humpries LL, Meek QC, Neill JR, Martin WL, Hays LR, Wedlund PJ (1996) The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: screening costs and influence on clinical outcomes in psychiatry. Clin Pharmacol Ther 60:522-534
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 522-534
-
-
Chen, S.1
Chou, W.H.2
Blouin, R.A.3
Mao, Z.4
Humpries, L.L.5
Meek, Q.C.6
Neill, J.R.7
Martin, W.L.8
Hays, L.R.9
Wedlund, P.J.10
-
16
-
-
0031695414
-
Pilot study of cytochrome P450-2D6 genotype in a psychiatric state hospital
-
De Leon J, Barnhill J, Rogers T, Boyle J, Chou WH, Wedlund PJ (1998) Pilot study of cytochrome P450-2D6 genotype in a psychiatric state hospital. Am J Psychiatry 155:1278-1280
-
(1998)
Am J Psychiatry
, vol.155
, pp. 1278-1280
-
-
De Leon, J.1
Barnhill, J.2
Rogers, T.3
Boyle, J.4
Chou, W.H.5
Wedlund, P.J.6
-
17
-
-
0001697297
-
Extension of a pilot study: Impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness
-
Chou WH, Yan FX, De Leon J, Barnhill J, Roger T, Cronin M, Pho M, Xiao V, Ryder TB, Liu WW, Teiling C, Wedlund PJ (2000) Extension of a pilot study: impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness. J Clin Psychopharmacol 20:246-251
-
(2000)
J Clin Psychopharmacol
, vol.20
, pp. 246-251
-
-
Chou, W.H.1
Yan, F.X.2
De Leon, J.3
Barnhill, J.4
Roger, T.5
Cronin, M.6
Pho, M.7
Xiao, V.8
Ryder, T.B.9
Liu, W.W.10
Teiling, C.11
Wedlund, P.J.12
-
19
-
-
0029846193
-
Rapid detection of CYP2D6 null alleles by long distance and multiplex-polymerase chain reaction
-
Stüven T, Griese E-U, Kroemer HK, Eichelbaum M, Zanger UM (1996) Rapid detection of CYP2D6 null alleles by long distance and multiplex-polymerase chain reaction. Pharmacogenetics 6:417-421
-
(1996)
Pharmacogenetics
, vol.6
, pp. 417-421
-
-
Stüven, T.1
Griese, E.-U.2
Kroemer, H.K.3
Eichelbaum, M.4
Zanger, U.M.5
-
20
-
-
0007293059
-
Ultrarapid metabolizers of debrisoquin: Characterisation and PCR-based detection of alleles with duplication of the CYP2D6 gene
-
Løvlie R, Daly AK, Molven A, Idle JR, Steen VM (1996) Ultrarapid metabolizers of debrisoquin: characterisation and PCR-based detection of alleles with duplication of the CYP2D6 gene. FEBS Lett 392:30-34
-
(1996)
FEBS Lett
, vol.392
, pp. 30-34
-
-
Løvlie, R.1
Daly, A.K.2
Molven, A.3
Idle, J.R.4
Steen, V.M.5
-
21
-
-
0031923119
-
Ultrarapid drug metabolism: PCR-based detection of CYP2D6 gene duplication
-
Steijns LWS, van der Weide J (1998) Ultrarapid drug metabolism: PCR-based detection of CYP2D6 gene duplication. Clin Chem 44:914-917
-
(1998)
Clin Chem
, vol.44
, pp. 914-917
-
-
Steijns, L.W.S.1
Van Der Weide, J.2
-
22
-
-
85039663440
-
-
Washington DC, USA
-
Flockhart DA Web site of the Georgetown University Medical Center (Washington DC, USA) on http://www.dml.georgetown.edu/depts/pharmacology/davetab.html
-
-
-
-
24
-
-
0032983850
-
CYP2D6 and CYP2C19 activity in a large population of Dutch healthy volunteers: Indications for oral contraceptive-related gender differences
-
Tamminga WJ, Wemer J, Oosterhuis B, Wieling J, Wilffert B, De Leij LFMH, De Zeeuw RA, Jonkman JHG (1999) CYP2D6 and CYP2C19 activity in a large population of Dutch healthy volunteers: indications for oral contraceptive-related gender differences. Eur J Clin Pharmacol 55:177-184
-
(1999)
Eur J Clin Pharmacol
, vol.55
, pp. 177-184
-
-
Tamminga, W.J.1
Wemer, J.2
Oosterhuis, B.3
Wieling, J.4
Wilffert, B.5
De Leij, L.F.M.H.6
De Zeeuw, R.A.7
Jonkman, J.H.G.8
-
25
-
-
0029049844
-
Polymorphic drug metabolism in schizophrenic patients with tardive dyskinesia
-
Arthur H, Dahl ML, Siwers B, Sjöqvist F (1995) Polymorphic drug metabolism in schizophrenic patients with tardive dyskinesia. J Clin Pschopharmacol 15:211-216
-
(1995)
J Clin Pschopharmacol
, vol.15
, pp. 211-216
-
-
Arthur, H.1
Dahl, M.L.2
Siwers, B.3
Sjöqvist, F.4
-
26
-
-
0030659112
-
Seizures and myoclonus associated with antidepressant treatment: Assessment of potential risk factors, including CYP2D6 and CYP2C19 polymorphisms, and treatment with CYP2D6 inhibitors
-
Spiget O, Hedenmalm K, Dahl ML, Wiholm BE, Dahlqvist R (1997) Seizures and myoclonus associated with antidepressant treatment: assessment of potential risk factors, including CYP2D6 and CYP2C19 polymorphisms, and treatment with CYP2D6 inhibitors. Acta Psychiatr Scand 96:379-384
-
(1997)
Acta Psychiatr Scand
, vol.96
, pp. 379-384
-
-
Spiget, O.1
Hedenmalm, K.2
Dahl, M.L.3
Wiholm, B.E.4
Dahlqvist, R.5
-
27
-
-
0033043227
-
Clomipramine concentrations as a predictor of delayed response: A naturalistic study
-
Gex-Fabry M, Balant-Gorgia AE, Balant LP (1999) Clomipramine concentrations as a predictor of delayed response: a naturalistic study. Eur J Clin Pharmacol 54:895-902
-
(1999)
Eur J Clin Pharmacol
, vol.54
, pp. 895-902
-
-
Gex-Fabry, M.1
Balant-Gorgia, A.E.2
Balant, L.P.3
-
28
-
-
0032821401
-
Failure to respond to treatment with typical antipsychotics is not associated with CYP2D6 ultrarapid hydroxylation
-
Aitchison JA, Munro J, Wright P, Smith S, Makoff AJ, Sachse C, Sham PC, Murray RM, Collier DA, Kerwin RW (1999) Failure to respond to treatment with typical antipsychotics is not associated with CYP2D6 ultrarapid hydroxylation. Br J Clin Pharmacol 48:388-394
-
(1999)
Br J Clin Pharmacol
, vol.48
, pp. 388-394
-
-
Aitchison, J.A.1
Munro, J.2
Wright, P.3
Smith, S.4
Makoff, A.J.5
Sachse, C.6
Sham, P.C.7
Murray, R.M.8
Collier, D.A.9
Kerwin, R.W.10
-
29
-
-
0032847231
-
Influence of CYP2D6 activity on the disposition and cardiovascular toxicity of the antidepressant agent venlafaxine in humans
-
Lessard E, Yessine MA, Hamelin BA, O'Hara G, LeBlanc J, Turgeon J (1999) Influence of CYP2D6 activity on the disposition and cardiovascular toxicity of the antidepressant agent venlafaxine in humans. Pharmacogenetics 9:435-443
-
(1999)
Pharmacogenetics
, vol.9
, pp. 435-443
-
-
Lessard, E.1
Yessine, M.A.2
Hamelin, B.A.3
O'Hara, G.4
LeBlanc, J.5
Turgeon, J.6
-
30
-
-
0032880890
-
Correlations between in vitro affinity of antipsychotics to various central neurotransmitter receptors and clinical incidence of their adverse drug reactions
-
Sekine Y, Rikihisa T, Ogata H, Echizen H, Arakawa Y (1999) Correlations between in vitro affinity of antipsychotics to various central neurotransmitter receptors and clinical incidence of their adverse drug reactions. Eur J Clin Pharmacol 55:583-587
-
(1999)
Eur J Clin Pharmacol
, vol.55
, pp. 583-587
-
-
Sekine, Y.1
Rikihisa, T.2
Ogata, H.3
Echizen, H.4
Arakawa, Y.5
-
31
-
-
0034612110
-
Pharmacogenetic prediction of clozapine response
-
Arranz MJ, Munro J, Birkett J, Bolonna A, Mancama D, Sodhi M, Lesch KP, Meyer JFW, Sham P, Collier DA, Muray RM, Kerwin RW (2000) Pharmacogenetic prediction of clozapine response. The Lancet 355:1615-1616
-
(2000)
The Lancet
, vol.355
, pp. 1615-1616
-
-
Arranz, M.J.1
Munro, J.2
Birkett, J.3
Bolonna, A.4
Mancama, D.5
Sodhi, M.6
Lesch, K.P.7
Meyer, J.F.W.8
Sham, P.9
Collier, D.A.10
Muray, R.M.11
Kerwin, R.W.12
-
32
-
-
0033973925
-
Pharmacogenetic methods as a complement to therapeutic monitoring of antidepressants and neuroleptics
-
Dahl M-L, Sjöqvist F (2000) Pharmacogenetic methods as a complement to therapeutic monitoring of antidepressants and neuroleptics. Ther Drug Monit 22:114-117
-
(2000)
Ther Drug Monit
, vol.22
, pp. 114-117
-
-
Dahl, M.-L.1
Sjöqvist, F.2
-
33
-
-
0034894010
-
CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: A first step towards subpopulation-specific dosages
-
Kirchheiner J, Brosen K, Dahl ML, Gram LF, Kasper S, Roots I, Sjöqvist F, Spina E, Bröckmöller J (2001) CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages. Acta Psychiatr Scand 104:173-192
-
(2001)
Acta Psychiatr Scand
, vol.104
, pp. 173-192
-
-
Kirchheiner, J.1
Brosen, K.2
Dahl, M.L.3
Gram, L.F.4
Kasper, S.5
Roots, I.6
Sjöqvist, F.7
Spina, E.8
Bröckmöller, J.9
|