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Volumn 5, Issue 2, 2012, Pages 101-103

Translation of pharmacogenetics to clinical practice: What will it take?

Author keywords

clopidogrel; genetic testing; personalized medicine; pharmacogenetics

Indexed keywords

ANTIDEPRESSANT AGENT; ARYLDIALKYLPHOSPHATASE 1; CARBAMAZEPINE; CLOPIDOGREL; CODEINE; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; FLUOROURACIL; HLA B ANTIGEN; IRINOTECAN; MORPHINE; NEUROLEPTIC AGENT; PHENYTOIN; TAMOXIFEN; WARFARIN;

EID: 84858422325     PISSN: 17512433     EISSN: 17512441     Source Type: Journal    
DOI: 10.1586/ecp.11.77     Document Type: Review
Times cited : (5)

References (16)
  • 2
    • 79960553096 scopus 로고    scopus 로고
    • Facilitating clinical implementation of pharmacogenomics
    • Mrazek DA, Lerman C. Facilitating clinical implementation of pharmacogenomics. J. Amer. Med. Assoc. 306, 304-305 (2011).
    • (2011) J. Amer. Med. Assoc. , vol.306 , pp. 304-305
    • Mrazek, D.A.1    Lerman, C.2
  • 3
    • 33749321054 scopus 로고    scopus 로고
    • CYP2C19.2 polymorphism contributes to a diminished pharmacodynamic response to clopidogrel
    • Brandt JT, Kirkwood S, Mukopadhay N. CYP2C19. 2 polymorphism contributes to a diminished pharmacodynamic response to clopidogrel. J. Am. Coll. Cardiol. 47(Suppl.), 380A (2006).
    • (2006) J. Am. Coll. Cardiol. , vol.47 SUPPL.
    • Brandt, J.T.1    Kirkwood, S.2    Mukopadhay, N.3
  • 4
    • 69249219296 scopus 로고    scopus 로고
    • Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
    • Shuldiner AR, O'Connell JR, Bliden KP et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA 302(8), 849-857 (2009).
    • (2009) JAMA , vol.302 , Issue.8 , pp. 849-857
    • Shuldiner, A.R.1    O'Connell, J.R.2    Bliden, K.P.3
  • 5
    • 58249135635 scopus 로고    scopus 로고
    • Cytochrome P450 CYP 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study
    • Collet JP, Hulot JS, Pena A, Villard E, Estave JB, Silvain J. Cytochrome P450 CYP 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study. Lancet 373, 309-317 (2009).
    • (2009) Lancet , vol.373 , pp. 309-317
    • Collet, J.P.1    Hulot, J.S.2    Pena, A.3    Villard, E.4    Estave, J.B.5    Silvain, J.6
  • 6
    • 65249145201 scopus 로고    scopus 로고
    • Cytochrome P450 2C 19 loss-of-function polymorphism and stent thrombosis following coronary intervention
    • Sibbing D, Stegherr J, Latz W, Koch W, Mehilli J, Dorrier K. Cytochrome P450 2C 19 loss-of-function polymorphism and stent thrombosis following coronary intervention. Eur. Heart J. 30, 916-922 (2009).
    • (2009) Eur. Heart J. , vol.30 , pp. 916-922
    • Sibbing, D.1    Stegherr, J.2    Latz, W.3    Koch, W.4    Mehilli, J.5    Dorrier, K.6
  • 7
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome P-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD et al. Cytochrome P-450 polymorphisms and response to clopidogrel. N. Engl. J. Med. 360, 354-362 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 8
    • 77957310177 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 polymorphism, suboptimal reperfusion and all-cause mortality in patients with acute myocardial infarction
    • Malek LA, Przyluski J, Spiewak M et al. Cytochrome P450 2C19 polymorphism, suboptimal reperfusion and all-cause mortality in patients with acute myocardial infarction. Cardiology 117(2), 81-87 (2010).
    • (2010) Cardiology , vol.117 , Issue.2 , pp. 81-87
    • Malek, L.A.1    Przyluski, J.2    Spiewak, M.3
  • 9
    • 84858999257 scopus 로고    scopus 로고
    • Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: Systematic review and meta-analysis
    • doi:10.1136/bmj.d4588 Epub ahead of print
    • Bauer T, Boumann HJ, van Werkum JW, Ford NF, ten Berg JM, Taubert D. Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: systematic review and meta-analysis. Br. Med. J. doi:10.1136/bmj.d4588 (2011) (Epub ahead of print).
    • (2011) Br. Med. J.
    • Bauer, T.1    Boumann, H.J.2    Van Werkum, J.W.3    Ford, N.F.4    Ten Berg, J.M.5    Taubert, D.6
  • 10
    • 78651239845 scopus 로고    scopus 로고
    • Paraoxonase-1 is a major determinant of clopidogrel efficacy
    • Bouman HJ, Schomig E, van Werkum JW et al. Paraoxonase-1 is a major determinant of clopidogrel efficacy. Nat. Med. 17(1), 110-116 (2010).
    • (2010) Nat. Med. , vol.17 , Issue.1 , pp. 110-116
    • Bouman, H.J.1    Schomig, E.2    Van Werkum, J.W.3
  • 11
    • 82955240702 scopus 로고    scopus 로고
    • CYP2C19 but not PON1 genetic variants influence clopidogrel pharmacokinetics, pharmacodynamics, and clinical efficacy in post-myocardial infarction patients
    • Hulot JS, Collet JP, Cayla G et al. CYP2C19 but not PON1 genetic variants influence clopidogrel pharmacokinetics, pharmacodynamics, and clinical efficacy in post-myocardial infarction patients. Circ. Cardiovasc. Interv. 1, 4(5), 422-428 (2011).
    • (2011) Circ. Cardiovasc. Interv. , vol.1 , Issue.4-5 , pp. 422-428
    • Hulot, J.S.1    Collet, J.P.2    Cayla, G.3
  • 12
    • 81855211733 scopus 로고    scopus 로고
    • Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease
    • doi:10.1001/jama.2011.1703 Epub ahead of print
    • Mega JL, Hochholzer W, Frelinger AL 3rd et al. Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease. JAMA doi:10.1001/jama.2011.1703 (2011) (Epub ahead of print).
    • (2011) JAMA
    • Mega, J.L.1    Hochholzer, W.2    Frelinger III, A.L.3
  • 13
    • 84872330167 scopus 로고    scopus 로고
    • Clopidogrel resistance: Where are we now
    • doi:10.1111/j.1755-5922.2011.00296.x. Epub ahead of print
    • Qureshi Z, Hobson AR. Clopidogrel 'resistance': where are we now? Cardiovasc. Ther. doi:10.1111/j.1755-5922.2011.00296.x. (2011) (Epub ahead of print).
    • (2011) Cardiovasc. Ther.
    • Qureshi, Z.1    Hobson, A.R.2
  • 14
    • 80053232385 scopus 로고    scopus 로고
    • The pharmacogenetics of antiplatelet agents: Towards personalized therapy
    • Ahmad T, Voora D, Becker RC. The pharmacogenetics of antiplatelet agents: Towards personalized therapy? Nat. Rev. Cardiol. 8, 560-571 (2011).
    • (2011) Nat. Rev. Cardiol. , vol.8 , pp. 560-571
    • Ahmad, T.1    Voora, D.2    Becker, R.C.3
  • 16
    • 77957172283 scopus 로고    scopus 로고
    • Pharmacogenomics instruction in US and Canadian medical schools: Implications for personalized medicine
    • Green JS, O'Brien TJ, Chiappinelli VA, Harralson AF. Pharmacogenomics instruction in US and Canadian medical schools: Implications for personalized medicine. Pharmacogenomics 11, 1331-1340 (2010).
    • (2010) Pharmacogenomics , vol.11 , pp. 1331-1340
    • Green, J.S.1    O'Brien, T.J.2    Chiappinelli, V.A.3    Harralson, A.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.