Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors

Development (Cambridge)

Volumn 142, Issue 1, 2015, Pages 70-81

  Karamitros, Dimitris ^a   Patmanidi, Alexandra L ^a   Kotantaki, Panoraia ^a   Potocnik, Alexandre J ^b   Bähr Ivacevic, Tomi ^c   Benes, Vladimir ^c   Lygerou, Zoi ^a   Kioussis, Dimitris ^b   Taraviras, Stavros ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Cell cycle; Epigenetic regulation; Fetal hematopoiesis; Geminin; HoxA9; Mouse; Transcriptional regulation

Indexed keywords

GEMININ; RNA POLYMERASE II; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR HOXA10; TRANSCRIPTION FACTOR HOXA9; BETA 2 MICROGLOBULIN; POLYCOMB REPRESSIVE COMPLEX 2; TRANSCRIPTOME; HISTONE; HOMEODOMAIN PROTEIN; SUZ12 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CHROMATIN; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; ERYTHROCYTE; FETUS LIVER; GENE DELETION; GENE LOCUS; GENE SILENCING; GENETIC TRANSCRIPTION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HISTONE MODIFICATION; HUMAN; HUMAN CELL; MEGAKARYOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; BLOOD CELL; CELL MATURATION; FETUS; FETUS DEVELOPMENT; GENE CONTROL; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ASSOCIATION; HEMATOPOIETIC SYSTEM; IN VIVO STUDY; K562 CELL LINE; LETHALITY; METHYLATION; STEM CELL; TRANSCRIPTION INITIATION; ANIMAL; CELL COUNT; CELL LINEAGE; CELL PROLIFERATION; CYTOLOGY; DEFICIENCY; EMBRYO DEATH; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENE ONTOLOGY; GENETIC EPIGENESIS; GENETICS; LIVER; METABOLISM; PATHOLOGY; PROTEIN PROCESSING; REGULATORY SEQUENCE;

MURINAE;

ANIMALS; CELL COUNT; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; EMBRYO LOSS; EPIGENESIS, GENETIC; FETUS; GEMININ; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE ONTOLOGY; GENETIC LOCI; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; K562 CELLS; LIVER; MICE; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN PROCESSING, POST-TRANSLATIONAL; REGULATORY SEQUENCES, NUCLEIC ACID; TRANSCRIPTION FACTORS; TRANSCRIPTOME;

EID: 84920511567     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.109454     Document Type: Article

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