Protective role of SIRT5 against motor deficit and dopaminergic degeneration in MPTP-induced mice model of Parkinson's disease

Behavioural Brain Research

Volumn 281, Issue , 2015, Pages 215-221

  Liu, Lei ^a   Peritore, Carina ^a   Ginsberg, Jessica ^a   Shih, Jennifer ^a   Arun, Siddharth ^a   Donmez, Gizem ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Behavior; Mitochondria; MPTP; Parkinson's disease; SIRT5; Sirtuin

Indexed keywords

MANGANESE SUPEROXIDE DISMUTASE; SIRTUIN 5; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; NEUROPROTECTIVE AGENT; SIRT5 PROTEIN, MOUSE; SIRTUIN; SUPEROXIDE DISMUTASE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; DOPAMINERGIC NERVE CELL; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; GENOTYPE; LOCOMOTION; MOTOR COORDINATION; MOTOR DYSFUNCTION; MOUSE; MPTP-INDUCED PARKINSONISM; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OPEN FIELD BEHAVIOR; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; COMPLICATION; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; INTOXICATION; KNOCKOUT MOUSE; MALE; METABOLISM; MITOCHONDRION; MOTOR ACTIVITY; NERVE DEGENERATION; PARKINSON DISEASE; PATHOLOGY; PATHOPHYSIOLOGY;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; MOTOR ACTIVITY; MPTP POISONING; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE; SIRTUINS; SUPEROXIDE DISMUTASE;

EID: 84920179057     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2014.12.035     Document Type: Article

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