-
1
-
-
0028048223
-
Differential expression of five N-methyl-d-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats
-
Akazawa C, Shigemoto R, Bessho Y, Nakanishi S & Mizuno N (1994). Differential expression of five N-methyl-d-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats. J Comp Neurol 347, 150-160.
-
(1994)
J Comp Neurol
, vol.347
, pp. 150-160
-
-
Akazawa, C.1
Shigemoto, R.2
Bessho, Y.3
Nakanishi, S.4
Mizuno, N.5
-
3
-
-
34547652875
-
NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus
-
Al-Hallaq RA, Conrads TP, Veenstra TD & Wenthold RJ (2007). NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus. J Neurosci 27, 8334-8343.
-
(2007)
J Neurosci
, vol.27
, pp. 8334-8343
-
-
Al-Hallaq, R.A.1
Conrads, T.P.2
Veenstra, T.D.3
Wenthold, R.J.4
-
4
-
-
0023929233
-
The role of divalent cations in the N-methyl-d-aspartate responses of mouse central neurones in culture
-
Ascher P & Nowak L (1988). The role of divalent cations in the N-methyl-d-aspartate responses of mouse central neurones in culture. J Physiol 399, 247-266.
-
(1988)
J Physiol
, vol.399
, pp. 247-266
-
-
Ascher, P.1
Nowak, L.2
-
5
-
-
0026727807
-
Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor
-
Burnashev N, Schoepfer R, Monyer H, Ruppersberg JP, Gunther W, Seeburg PH & Sakmann B (1992). Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor. Science 257, 1415-1419.
-
(1992)
Science
, vol.257
, pp. 1415-1419
-
-
Burnashev, N.1
Schoepfer, R.2
Monyer, H.3
Ruppersberg, J.P.4
Gunther, W.5
Seeburg, P.H.6
Sakmann, B.7
-
6
-
-
0029028313
-
Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes
-
Burnashev N, Zhou Z, Neher E & Sakmann B (1995). Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes. J Physiol 485, 403-418.
-
(1995)
J Physiol
, vol.485
, pp. 403-418
-
-
Burnashev, N.1
Zhou, Z.2
Neher, E.3
Sakmann, B.4
-
7
-
-
0033566918
-
Subtype-dependence of NMDA receptor channel open probability
-
Chen N, Luo T & Raymond LA (1999). Subtype-dependence of NMDA receptor channel open probability. J Neurosci 19, 6844-6854.
-
(1999)
J Neurosci
, vol.19
, pp. 6844-6854
-
-
Chen, N.1
Luo, T.2
Raymond, L.A.3
-
8
-
-
0030997418
-
Differential sensitivity of recombinant N-methyl-d-aspartate receptor subtypes to zinc inhibition
-
Chen N, Moshaver A & Raymond LA (1997). Differential sensitivity of recombinant N-methyl-d-aspartate receptor subtypes to zinc inhibition. Mol Pharmacol 51, 1015-1023.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 1015-1023
-
-
Chen, N.1
Moshaver, A.2
Raymond, L.A.3
-
9
-
-
37849009751
-
Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes
-
Chen PE, Geballe MT, Katz E, Erreger K, Livesey MR, O'Toole KK, Le P, Lee CJ, Snyder JP, Traynelis SF & Wyllie DJ (2008). Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. J Physiol 586, 227-245.
-
(2008)
J Physiol
, vol.586
, pp. 227-245
-
-
Chen, P.E.1
Geballe, M.T.2
Katz, E.3
Erreger, K.4
Livesey, M.R.5
O'Toole, K.K.6
Le, P.7
Lee, C.J.8
Snyder, J.P.9
Traynelis, S.F.10
Wyllie, D.J.11
-
11
-
-
0033136273
-
2+ inhibition of the NMDA receptor
-
2+ inhibition of the NMDA receptor. Neuron 23, 171-180.
-
(1999)
Neuron
, vol.23
, pp. 171-180
-
-
Choi, Y.B.1
Lipton, S.A.2
-
12
-
-
33744966861
-
NMDA receptor NR2 subunit dependence of the slow component of magnesium unblock
-
Clarke RJ (2006). NMDA receptor NR2 subunit dependence of the slow component of magnesium unblock. J Neurosci 26, 5825-5834.
-
(2006)
J Neurosci
, vol.26
, pp. 5825-5834
-
-
Clarke, R.J.1
-
14
-
-
57049105073
-
Voltage-dependent gating of NR1/2B NMDA receptors
-
Clarke RJ & Johnson JW (2008). Voltage-dependent gating of NR1/2B NMDA receptors. J Physiol 586, 5727-5741.
-
(2008)
J Physiol
, vol.586
, pp. 5727-5741
-
-
Clarke, R.J.1
Johnson, J.W.2
-
15
-
-
16544376850
-
Role of distinct NMDA receptor subtypes at central synapses
-
Cull-Candy SG & Leszkiewicz DN (2004). Role of distinct NMDA receptor subtypes at central synapses. Sci STKE 2004, re16.
-
(2004)
Sci STKE
, vol.2004
, pp. re16
-
-
Cull-Candy, S.G.1
Leszkiewicz, D.N.2
-
16
-
-
0032478818
-
+ conduction and selectivity
-
+ conduction and selectivity. Science 280, 69-77.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Morais Cabral, J.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
17
-
-
51849143750
-
Activation of recombinant NR1/NR2C NMDA receptors
-
Dravid SM, Prakash A & Traynelis SF (2008). Activation of recombinant NR1/NR2C NMDA receptors. J Physiol 586, 4425-4439.
-
(2008)
J Physiol
, vol.586
, pp. 4425-4439
-
-
Dravid, S.M.1
Prakash, A.2
Traynelis, S.F.3
-
18
-
-
14944364531
-
Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles
-
Erreger K, Dravid SM, Banke TG, Wyllie DJ & Traynelis SF (2005). Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles. J Physiol 563, 345-358.
-
(2005)
J Physiol
, vol.563
, pp. 345-358
-
-
Erreger, K.1
Dravid, S.M.2
Banke, T.G.3
Wyllie, D.J.4
Traynelis, S.F.5
-
19
-
-
34748926290
-
Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-d-aspartate glutamate receptors
-
Erreger K, Geballe MT, Kristensen A, Chen PE, Hansen KB, Lee CJ, Yuan H, Le P, Lyuboslavsky PN, Micale N, Jorgensen L, Clausen RP, Wyllie DJ, Snyder JP & Traynelis SF (2007). Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-d-aspartate glutamate receptors. Mol Pharmacol 72, 907-920.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 907-920
-
-
Erreger, K.1
Geballe, M.T.2
Kristensen, A.3
Chen, P.E.4
Hansen, K.B.5
Lee, C.J.6
Yuan, H.7
Le, P.8
Lyuboslavsky, P.N.9
Micale, N.10
Jorgensen, L.11
Clausen, R.P.12
Wyllie, D.J.13
Snyder, J.P.14
Traynelis, S.F.15
-
20
-
-
38849170353
-
Zinc inhibition of rat NR1/NR2A N-methyl-d-aspartate receptors
-
Erreger K & Traynelis SF (2008). Zinc inhibition of rat NR1/NR2A N-methyl-d-aspartate receptors. J Physiol 586, 763-778.
-
(2008)
J Physiol
, vol.586
, pp. 763-778
-
-
Erreger, K.1
Traynelis, S.F.2
-
22
-
-
0023856147
-
Slow excitatory postsynaptic currents mediated by N-methyl-d-aspartate receptors on cultured mouse central neurones
-
Forsythe ID & Westbrook GL (1988). Slow excitatory postsynaptic currents mediated by N-methyl-d-aspartate receptors on cultured mouse central neurones. J Physiol 396, 515-533.
-
(1988)
J Physiol
, vol.396
, pp. 515-533
-
-
Forsythe, I.D.1
Westbrook, G.L.2
-
23
-
-
27744500994
-
Subunit arrangement and function in NMDA receptors
-
Furukawa H, Singh SK, Mancusso R & Gouaux E (2005). Subunit arrangement and function in NMDA receptors. Nature 438, 185-192.
-
(2005)
Nature
, vol.438
, pp. 185-192
-
-
Furukawa, H.1
Singh, S.K.2
Mancusso, R.3
Gouaux, E.4
-
24
-
-
0030803667
-
The NR2B-specific interactions of polyamines and protons with the N-methyl-d-aspartate receptor
-
Gallagher MJ, Huang H, Grant ER & Lynch DR (1997). The NR2B-specific interactions of polyamines and protons with the N-methyl-d-aspartate receptor. J Biol Chem 272, 24971-24979.
-
(1997)
J Biol Chem
, vol.272
, pp. 24971-24979
-
-
Gallagher, M.J.1
Huang, H.2
Grant, E.R.3
Lynch, D.R.4
-
25
-
-
37549045649
-
Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition
-
Gielen M, Le Goff A, Stroebel D, Johnson JW, Neyton J & Paoletti P (2008). Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition. Neuron 57, 80-93.
-
(2008)
Neuron
, vol.57
, pp. 80-93
-
-
Gielen, M.1
Le Goff, A.2
Stroebel, D.3
Johnson, J.W.4
Neyton, J.5
Paoletti, P.6
-
26
-
-
66649086928
-
Mechanism of differential control of NMDA receptor activity by NR2 subunits
-
Gielen M, Siegler Retchless B, Mony L, Johnson JW & Paoletti P (2009). Mechanism of differential control of NMDA receptor activity by NR2 subunits. Nature 459, 703-707.
-
(2009)
Nature
, vol.459
, pp. 703-707
-
-
Gielen, M.1
Siegler Retchless, B.2
Mony, L.3
Johnson, J.W.4
Paoletti, P.5
-
27
-
-
80052188595
-
Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo
-
Gray JA, Shi Y, Usui H, During MJ, Sakimura K & Nicoll RA (2011). Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo. Neuron 71, 1085-1101.
-
(2011)
Neuron
, vol.71
, pp. 1085-1101
-
-
Gray, J.A.1
Shi, Y.2
Usui, H.3
During, M.J.4
Sakimura, K.5
Nicoll, R.A.6
-
28
-
-
56749185869
-
Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-d-aspartate receptor
-
Han X, Tomitori H, Mizuno S, Higashi K, Full C, Fukiwake T, Terui Y, Leewanich P, Nishimura K, Toida T, Williams K, Kashiwagi K & Igarashi K (2008). Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-d-aspartate receptor. J Neurochem 107, 1566-1577.
-
(2008)
J Neurochem
, vol.107
, pp. 1566-1577
-
-
Han, X.1
Tomitori, H.2
Mizuno, S.3
Higashi, K.4
Full, C.5
Fukiwake, T.6
Terui, Y.7
Leewanich, P.8
Nishimura, K.9
Toida, T.10
Williams, K.11
Kashiwagi, K.12
Igarashi, K.13
-
29
-
-
84895480210
-
Distinct functional and pharmacological properties of triheteromeric GluN1/GluN2A/GluN2B NMDA receptors
-
Hansen KB, Ogden KK, Yuan H & Traynelis SF (2014). Distinct functional and pharmacological properties of triheteromeric GluN1/GluN2A/GluN2B NMDA receptors. Neuron 81, 1084-1096.
-
(2014)
Neuron
, vol.81
, pp. 1084-1096
-
-
Hansen, K.B.1
Ogden, K.K.2
Yuan, H.3
Traynelis, S.F.4
-
30
-
-
77956917231
-
Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders
-
Hardingham GE & Bading H (2010). Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci 11, 682-696.
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 682-696
-
-
Hardingham, G.E.1
Bading, H.2
-
31
-
-
17444426068
-
Modulation of triheteromeric NMDA receptors by N-terminal domain ligands
-
Hatton CJ & Paoletti P (2005). Modulation of triheteromeric NMDA receptors by N-terminal domain ligands. Neuron 46, 261-274.
-
(2005)
Neuron
, vol.46
, pp. 261-274
-
-
Hatton, C.J.1
Paoletti, P.2
-
32
-
-
0028987938
-
+ channel pore through mutant cycles with a peptide inhibitor
-
+ channel pore through mutant cycles with a peptide inhibitor. Science 268, 307-310.
-
(1995)
Science
, vol.268
, pp. 307-310
-
-
Hidalgo, P.1
MacKinnon, R.2
-
34
-
-
0023091647
-
Glycine potentiates the NMDA response in cultured mouse brain neurons
-
Johnson JW & Ascher P (1987). Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325, 529-531.
-
(1987)
Nature
, vol.325
, pp. 529-531
-
-
Johnson, J.W.1
Ascher, P.2
-
35
-
-
84901640125
-
Crystal structure of a heterotetrameric NMDA receptor ion channel
-
Karakas E & Furukawa H (2014). Crystal structure of a heterotetrameric NMDA receptor ion channel. Science 344, 992-997.
-
(2014)
Science
, vol.344
, pp. 992-997
-
-
Karakas, E.1
Furukawa, H.2
-
36
-
-
72449151659
-
Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit
-
Karakas E, Simorowski N & Furukawa H (2009). Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. EMBO J 28, 3910-3920.
-
(2009)
EMBO J
, vol.28
, pp. 3910-3920
-
-
Karakas, E.1
Simorowski, N.2
Furukawa, H.3
-
37
-
-
79960417429
-
Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors
-
Karakas E, Simorowski N & Furukawa H (2011). Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature 475, 249-253.
-
(2011)
Nature
, vol.475
, pp. 249-253
-
-
Karakas, E.1
Simorowski, N.2
Furukawa, H.3
-
38
-
-
0023754192
-
Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes
-
Kleckner NW & Dingledine R (1988). Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science 241, 835-837.
-
(1988)
Science
, vol.241
, pp. 835-837
-
-
Kleckner, N.W.1
Dingledine, R.2
-
39
-
-
0030000465
-
2+ block in NMDA receptor channels
-
2+ block in NMDA receptor channels. J Neurosci 16, 3549-3558.
-
(1996)
J Neurosci
, vol.16
, pp. 3549-3558
-
-
Kuner, T.1
Schoepfer, R.2
-
40
-
-
77956859010
-
NMDA receptors with locked glutamate-binding clefts open with high efficacy
-
Kussius CL & Popescu GK (2010). NMDA receptors with locked glutamate-binding clefts open with high efficacy. J Neurosci 30, 12474-12479.
-
(2010)
J Neurosci
, vol.30
, pp. 12474-12479
-
-
Kussius, C.L.1
Popescu, G.K.2
-
41
-
-
0026717250
-
Molecular diversity of the NMDA receptor channel
-
Kutsuwada T, Kashiwabuchi N, Mori H, Sakimura K, Kushiya E, Araki K, Meguro H, Masaki H, Kumanishi T, Arakawa M & Mishina M (1992). Molecular diversity of the NMDA receptor channel. Nature 358, 36-41.
-
(1992)
Nature
, vol.358
, pp. 36-41
-
-
Kutsuwada, T.1
Kashiwabuchi, N.2
Mori, H.3
Sakimura, K.4
Kushiya, E.5
Araki, K.6
Meguro, H.7
Masaki, H.8
Kumanishi, T.9
Arakawa, M.10
Mishina, M.11
-
42
-
-
77955570062
-
Glutamate receptors, neurotoxicity and neurodegeneration
-
Lau A & Tymianski M (2010). Glutamate receptors, neurotoxicity and neurodegeneration. Pflugers Arch 460, 525-542.
-
(2010)
Pflugers Arch
, vol.460
, pp. 525-542
-
-
Lau, A.1
Tymianski, M.2
-
43
-
-
84904199124
-
NMDA receptor structures reveal subunit arrangement and pore architecture
-
Lee C-H, Lu W, Michel JC, Goehring A, Du J, Song X & Gouaux E (2014). NMDA receptor structures reveal subunit arrangement and pore architecture. Nature 511, 191-197.
-
(2014)
Nature
, vol.511
, pp. 191-197
-
-
Lee, C.-H.1
Lu, W.2
Michel, J.C.3
Goehring, A.4
Du, J.5
Song, X.6
Gouaux, E.7
-
44
-
-
0025247748
-
Glycine decreases desensitization of N-methyl-d-aspartate (NMDA) receptors expressed in Xenopus oocytes and is required for NMDA responses
-
Lerma J, Zukin RS & Bennett MV (1990). Glycine decreases desensitization of N-methyl-d-aspartate (NMDA) receptors expressed in Xenopus oocytes and is required for NMDA responses. Proc Natl Acad Sci U S A 87, 2354-2358.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 2354-2358
-
-
Lerma, J.1
Zukin, R.S.2
Bennett, M.V.3
-
45
-
-
0025368726
-
Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents
-
Lester RA, Clements JD, Westbrook GL & Jahr CE (1990). Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents. Nature 346, 565-567.
-
(1990)
Nature
, vol.346
, pp. 565-567
-
-
Lester, R.A.1
Clements, J.D.2
Westbrook, G.L.3
Jahr, C.E.4
-
46
-
-
0037686667
-
Molecular determinants of proton-sensitive N-methyl-d-aspartate receptor gating
-
Low CM, Lyuboslavsky P, French A, Le P, Wyatte K, Thiel WH, Marchan EM, Igarashi K, Kashiwagi K, Gernert K, Williams K, Traynelis SF & Zheng F (2003). Molecular determinants of proton-sensitive N-methyl-d-aspartate receptor gating. Mol Pharmacol 63, 1212-1222.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 1212-1222
-
-
Low, C.M.1
Lyuboslavsky, P.2
French, A.3
Le, P.4
Wyatte, K.5
Thiel, W.H.6
Marchan, E.M.7
Igarashi, K.8
Kashiwagi, K.9
Gernert, K.10
Williams, K.11
Traynelis, S.F.12
Zheng, F.13
-
47
-
-
0034718494
-
Molecular determinants of coordinated proton and zinc inhibition of N-methyl-d-aspartate NR1/NR2A receptors
-
Low CM, Zheng F, Lyuboslavsky P & Traynelis SF (2000). Molecular determinants of coordinated proton and zinc inhibition of N-methyl-d-aspartate NR1/NR2A receptors. Proc Natl Acad Sci U S A 97, 11062-11067.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 11062-11067
-
-
Low, C.M.1
Zheng, F.2
Lyuboslavsky, P.3
Traynelis, S.F.4
-
48
-
-
0031032658
-
The majority of N-methyl-d-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B)
-
Luo J, Wang Y, Yasuda RP, Dunah AW & Wolfe BB (1997). The majority of N-methyl-d-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B). Mol Pharmacol 51, 79-86.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 79-86
-
-
Luo, J.1
Wang, Y.2
Yasuda, R.P.3
Dunah, A.W.4
Wolfe, B.B.5
-
49
-
-
0022479032
-
NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones
-
MacDermott AB, Mayer ML, Westbrook GL, Smith SJ & Barker JL (1986). NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones. Nature 321, 519-522.
-
(1986)
Nature
, vol.321
, pp. 519-522
-
-
MacDermott, A.B.1
Mayer, M.L.2
Westbrook, G.L.3
Smith, S.J.4
Barker, J.L.5
-
50
-
-
84867815125
-
C-terminal domains of N-methyl-d-aspartic acid receptor modulate unitary channel conductance and gating
-
Maki BA, Aman TK, Amico-Ruvio SA, Kussius CL & Popescu GK (2012). C-terminal domains of N-methyl-d-aspartic acid receptor modulate unitary channel conductance and gating. J Biol Chem 287, 36071-36080.
-
(2012)
J Biol Chem
, vol.287
, pp. 36071-36080
-
-
Maki, B.A.1
Aman, T.K.2
Amico-Ruvio, S.A.3
Kussius, C.L.4
Popescu, G.K.5
-
51
-
-
5344241223
-
LTP and LTD: an embarrassment of riches
-
Malenka RC & Bear MF (2004). LTP and LTD: an embarrassment of riches. Neuron 44, 5-21.
-
(2004)
Neuron
, vol.44
, pp. 5-21
-
-
Malenka, R.C.1
Bear, M.F.2
-
52
-
-
0344304828
-
Identification of critical residues in the amino terminal domain of the human NR2B subunit involved in the RO 25-6981 binding pocket
-
Malherbe P, Mutel V, Broger C, Perin-Dureau F, Kemp JA, Neyton J, Paoletti P & Kew JN (2003). Identification of critical residues in the amino terminal domain of the human NR2B subunit involved in the RO 25-6981 binding pocket. J Pharmacol Exp Ther 307, 897-905.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 897-905
-
-
Malherbe, P.1
Mutel, V.2
Broger, C.3
Perin-Dureau, F.4
Kemp, J.A.5
Neyton, J.6
Paoletti, P.7
Kew, J.N.8
-
53
-
-
84860653602
-
The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults
-
Martel M-A, Ryan TJ, Bell KFS, Fowler JH, McMahon A, Al-Mubarak B, Komiyama NH, Horsburgh K, Kind PC, Grant SGN, Wyllie DJA & Hardingham GE (2012). The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults. Neuron 74, 543-556.
-
(2012)
Neuron
, vol.74
, pp. 543-556
-
-
Martel, M.-A.1
Ryan, T.J.2
Bell, K.F.S.3
Fowler, J.H.4
McMahon, A.5
Al-Mubarak, B.6
Komiyama, N.H.7
Horsburgh, K.8
Kind, P.C.9
Grant, S.G.N.10
Wyllie, D.J.A.11
Hardingham, G.E.12
-
54
-
-
0033051714
-
A regulatory domain (R1-R2) in the amino terminus of the N-methyl-d-aspartate receptor: effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein
-
Masuko T, Kashiwagi K, Kuno T, Nguyen ND, Pahk AJ, Fukuchi J, Igarashi K & Williams K (1999). A regulatory domain (R1-R2) in the amino terminus of the N-methyl-d-aspartate receptor: effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein. Mol Pharmacol 55, 957-969.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 957-969
-
-
Masuko, T.1
Kashiwagi, K.2
Kuno, T.3
Nguyen, N.D.4
Pahk, A.J.5
Fukuchi, J.6
Igarashi, K.7
Williams, K.8
-
56
-
-
79961020657
-
Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines
-
Mony L, Zhu S, Carvalho S & Paoletti P (2011). Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines. EMBO J 30, 3134-3146.
-
(2011)
EMBO J
, vol.30
, pp. 3134-3146
-
-
Mony, L.1
Zhu, S.2
Carvalho, S.3
Paoletti, P.4
-
57
-
-
0028343648
-
Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
-
Monyer H, Burnashev N, Laurie DJ, Sakmann B & Seeburg PH (1994). Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12, 529-540.
-
(1994)
Neuron
, vol.12
, pp. 529-540
-
-
Monyer, H.1
Burnashev, N.2
Laurie, D.J.3
Sakmann, B.4
Seeburg, P.H.5
-
58
-
-
0026721811
-
Heteromeric NMDA receptors: molecular and functional distinction of subtypes
-
Monyer H, Sprengel R, Schoepfer R, Herb A, Higuchi M, Lomeli H, Burnashev N, Sakmann B & Seeburg PH (1992). Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science 256, 1217-1221.
-
(1992)
Science
, vol.256
, pp. 1217-1221
-
-
Monyer, H.1
Sprengel, R.2
Schoepfer, R.3
Herb, A.4
Higuchi, M.5
Lomeli, H.6
Burnashev, N.7
Sakmann, B.8
Seeburg, P.H.9
-
59
-
-
70349618426
-
Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies
-
Ng FM, Geballe MT, Snyder JP, Traynelis SF & Low CM (2008). Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies. Mol Brain 1, 16.
-
(2008)
Mol Brain
, vol.1
, pp. 16
-
-
Ng, F.M.1
Geballe, M.T.2
Snyder, J.P.3
Traynelis, S.F.4
Low, C.M.5
-
60
-
-
0021260967
-
Magnesium gates glutamate-activated channels in mouse central neurones
-
Nowak L, Bregestovski P, Ascher P, Herbet A & Prochiantz A (1984). Magnesium gates glutamate-activated channels in mouse central neurones. Nature 307, 462-465.
-
(1984)
Nature
, vol.307
, pp. 462-465
-
-
Nowak, L.1
Bregestovski, P.2
Ascher, P.3
Herbet, A.4
Prochiantz, A.5
-
61
-
-
70450184777
-
Single-channel properties of N-methyl-d-aspartate receptors containing chimaeric GluN2A/GluN2D subunits
-
O'Leary T & Wyllie DJ (2009). Single-channel properties of N-methyl-d-aspartate receptors containing chimaeric GluN2A/GluN2D subunits. Biochem Soc Trans 37, 1347-1354.
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 1347-1354
-
-
O'Leary, T.1
Wyllie, D.J.2
-
63
-
-
0030746608
-
High-affinity zinc inhibition of NMDA NR1-NR2A receptors
-
Paoletti P, Ascher P & Neyton J (1997). High-affinity zinc inhibition of NMDA NR1-NR2A receptors. J Neurosci 17, 5711-5725.
-
(1997)
J Neurosci
, vol.17
, pp. 5711-5725
-
-
Paoletti, P.1
Ascher, P.2
Neyton, J.3
-
64
-
-
84878254691
-
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
-
Paoletti P, Bellone C & Zhou Q (2013). NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat Rev Neurosci 14, 383-400.
-
(2013)
Nat Rev Neurosci
, vol.14
, pp. 383-400
-
-
Paoletti, P.1
Bellone, C.2
Zhou, Q.3
-
65
-
-
0034517709
-
Molecular organization of a zinc binding N-terminal modulatory domain in a NMDA receptor subunit
-
Paoletti P, Perin-Dureau F, Fayyazuddin A, Le Goff A, Callebaut I & Neyton J (2000). Molecular organization of a zinc binding N-terminal modulatory domain in a NMDA receptor subunit. Neuron 28, 911-925.
-
(2000)
Neuron
, vol.28
, pp. 911-925
-
-
Paoletti, P.1
Perin-Dureau, F.2
Fayyazuddin, A.3
Le Goff, A.4
Callebaut, I.5
Neyton, J.6
-
66
-
-
0029862192
-
AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate
-
Partin KM, Fleck MW & Mayer ML (1996). AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate. J Neurosci 16, 6634-6647.
-
(1996)
J Neurosci
, vol.16
, pp. 6634-6647
-
-
Partin, K.M.1
Fleck, M.W.2
Mayer, M.L.3
-
67
-
-
0037101607
-
Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors
-
Perin-Dureau F, Rachline J, Neyton J & Paoletti P (2002). Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors. J Neurosci 22, 5955-5965.
-
(2002)
J Neurosci
, vol.22
, pp. 5955-5965
-
-
Perin-Dureau, F.1
Rachline, J.2
Neyton, J.3
Paoletti, P.4
-
68
-
-
0028823737
-
Pharmacological properties of recombinant human N-methyl-d-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells
-
Priestley T, Laughton P, Myers J, Le Bourdelles B, Kerby J & Whiting PJ (1995). Pharmacological properties of recombinant human N-methyl-d-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells. Mol Pharmacol 48, 841-848.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 841-848
-
-
Priestley, T.1
Laughton, P.2
Myers, J.3
Le Bourdelles, B.4
Kerby, J.5
Whiting, P.J.6
-
69
-
-
84857064886
-
Influence of the intracellular GluN2 C-terminal domain on NMDA receptor function
-
Punnakkal P, Jendritza P & Kohr G (2012). Influence of the intracellular GluN2 C-terminal domain on NMDA receptor function. Neuropharmacology 62, 1985-1992.
-
(2012)
Neuropharmacology
, vol.62
, pp. 1985-1992
-
-
Punnakkal, P.1
Jendritza, P.2
Kohr, G.3
-
70
-
-
12144257176
-
The micromolar zinc-binding domain on the NMDA receptor subunit NR2B
-
Rachline J, Perin-Dureau F, Le Goff A, Neyton J & Paoletti P (2005). The micromolar zinc-binding domain on the NMDA receptor subunit NR2B. J Neurosci 25, 308-317.
-
(2005)
J Neurosci
, vol.25
, pp. 308-317
-
-
Rachline, J.1
Perin-Dureau, F.2
Le Goff, A.3
Neyton, J.4
Paoletti, P.5
-
71
-
-
77952052813
-
Subunit arrangement in N-methyl-d-aspartate (NMDA) receptors
-
Rambhadran A, Gonzalez J & Jayaraman V (2010). Subunit arrangement in N-methyl-d-aspartate (NMDA) receptors. J Biol Chem 285, 15296-15301.
-
(2010)
J Biol Chem
, vol.285
, pp. 15296-15301
-
-
Rambhadran, A.1
Gonzalez, J.2
Jayaraman, V.3
-
72
-
-
79953199424
-
Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-d-aspartate receptor population in adult hippocampal synapses
-
Rauner C & Kohr G (2010). Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-d-aspartate receptor population in adult hippocampal synapses. J Biol Chem 286, 7558-7566.
-
(2010)
J Biol Chem
, vol.286
, pp. 7558-7566
-
-
Rauner, C.1
Kohr, G.2
-
73
-
-
0035924573
-
Intersubunit cooperativity in the NMDA receptor
-
Regalado MP, Villarroel A & Lerma J (2001). Intersubunit cooperativity in the NMDA receptor. Neuron 32, 1085-1096.
-
(2001)
Neuron
, vol.32
, pp. 1085-1096
-
-
Regalado, M.P.1
Villarroel, A.2
Lerma, J.3
-
74
-
-
84859502370
-
An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors
-
Riou M, Stroebel D, Edwardson JM & Paoletti P (2012). An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors. PLoS One 7, e35134.
-
(2012)
PLoS One
, vol.7
, pp. e35134
-
-
Riou, M.1
Stroebel, D.2
Edwardson, J.M.3
Paoletti, P.4
-
75
-
-
84871720366
-
Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behaviour
-
Ryan TJ, Kopanitsa MV, Indersmitten T, Nithianantharajah J, Afinowi NO, Pettit C, Stanford LE, Sprengel R, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG & Komiyama NH (2013). Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behaviour. Nat Neurosci 16, 25-32.
-
(2013)
Nat Neurosci
, vol.16
, pp. 25-32
-
-
Ryan, T.J.1
Kopanitsa, M.V.2
Indersmitten, T.3
Nithianantharajah, J.4
Afinowi, N.O.5
Pettit, C.6
Stanford, L.E.7
Sprengel, R.8
Saksida, L.M.9
Bussey, T.J.10
O'Dell, T.J.11
Grant, S.G.12
Komiyama, N.H.13
-
77
-
-
0028988978
-
d-Serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release
-
Schell MJ, Molliver ME & Snyder SH (1995). d-Serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release. Proc Natl Acad Sci U S A 92, 3948-3952.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 3948-3952
-
-
Schell, M.J.1
Molliver, M.E.2
Snyder, S.H.3
-
78
-
-
0029658053
-
2+ influx and reversal potentials in recombinant N-methyl-d-aspartate receptor channels
-
2+ influx and reversal potentials in recombinant N-methyl-d-aspartate receptor channels. Biophys J 70, 2165-2174.
-
(1996)
Biophys J
, vol.70
, pp. 2165-2174
-
-
Schneggenburger, R.1
-
79
-
-
29244456432
-
Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits
-
Schorge S, Elenes S & Colquhoun D (2005). Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits. J Physiol 569, 395-418.
-
(2005)
J Physiol
, vol.569
, pp. 395-418
-
-
Schorge, S.1
Elenes, S.2
Colquhoun, D.3
-
80
-
-
0029056922
-
Energetics of protein-protein interactions: analysis of the barnase-barstar interface by single mutations and double mutant cycles
-
Schreiber G & Fersht AR (1995). Energetics of protein-protein interactions: analysis of the barnase-barstar interface by single mutations and double mutant cycles. J Mol Biol 248, 478-486.
-
(1995)
J Mol Biol
, vol.248
, pp. 478-486
-
-
Schreiber, G.1
Fersht, A.R.2
-
81
-
-
0028219211
-
Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
-
Sheng M, Cummings J, Roldan LA, Jan YN & Jan LY (1994). Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 368, 144-147.
-
(1994)
Nature
, vol.368
, pp. 144-147
-
-
Sheng, M.1
Cummings, J.2
Roldan, L.A.3
Jan, Y.N.4
Jan, L.Y.5
-
83
-
-
84862777495
-
A single GluN2 subunit residue controls NMDA receptor channel properties via intersubunit interaction
-
Siegler Retchless B, Gao W & Johnson JW (2012). A single GluN2 subunit residue controls NMDA receptor channel properties via intersubunit interaction. Nat Neurosci 15, 406-413.
-
(2012)
Nat Neurosci
, vol.15
, pp. 406-413
-
-
Siegler Retchless, B.1
Gao, W.2
Johnson, J.W.3
-
84
-
-
72049124287
-
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
-
Sobolevsky AI, Rosconi MP & Gouaux E (2009). X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature 462, 745-756.
-
(2009)
Nature
, vol.462
, pp. 745-756
-
-
Sobolevsky, A.I.1
Rosconi, M.P.2
Gouaux, E.3
-
85
-
-
78149495223
-
Functional evidence for a twisted conformation of the NMDA receptor GluN2A subunit N-terminal domain
-
Stroebel D, Carvalho S & Paoletti P (2011). Functional evidence for a twisted conformation of the NMDA receptor GluN2A subunit N-terminal domain. Neuropharmacology 60, 151-158.
-
(2011)
Neuropharmacology
, vol.60
, pp. 151-158
-
-
Stroebel, D.1
Carvalho, S.2
Paoletti, P.3
-
86
-
-
0032535032
-
Heterogeneity of homomeric GluR5 kainate receptor desensitization expressed in HEK293 cells
-
Swanson GT & Heinemann SF (1998). Heterogeneity of homomeric GluR5 kainate receptor desensitization expressed in HEK293 cells. J Physiol 513, 639-646.
-
(1998)
J Physiol
, vol.513
, pp. 639-646
-
-
Swanson, G.T.1
Heinemann, S.F.2
-
87
-
-
34247399105
-
Ion channels of glutamate receptors: structural modeling
-
Tikhonov DB (2007). Ion channels of glutamate receptors: structural modeling. Mol Membr Biol 24, 135-147.
-
(2007)
Mol Membr Biol
, vol.24
, pp. 135-147
-
-
Tikhonov, D.B.1
-
88
-
-
84877931450
-
Triheteromeric NMDA receptors at hippocampal synapses
-
Tovar KR, McGinley MJ & Westbrook GL (2013). Triheteromeric NMDA receptors at hippocampal synapses. J Neurosci 33, 9150-9160.
-
(2013)
J Neurosci
, vol.33
, pp. 9150-9160
-
-
Tovar, K.R.1
McGinley, M.J.2
Westbrook, G.L.3
-
89
-
-
0032529588
-
Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit
-
Traynelis SF, Burgess MF, Zheng F, Lyuboslavsky P & Powers JL (1998). Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit. J Neurosci 18, 6163-6175.
-
(1998)
J Neurosci
, vol.18
, pp. 6163-6175
-
-
Traynelis, S.F.1
Burgess, M.F.2
Zheng, F.3
Lyuboslavsky, P.4
Powers, J.L.5
-
90
-
-
0029021010
-
Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines
-
Traynelis SF, Hartley M & Heinemann SF (1995). Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines. Science 268, 873-876.
-
(1995)
Science
, vol.268
, pp. 873-876
-
-
Traynelis, S.F.1
Hartley, M.2
Heinemann, S.F.3
-
91
-
-
77952363301
-
Glutamate receptor ion channels: Structure, regulation, and function
-
Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ & Dingledine R (2010). Glutamate receptor ion channels: Structure, regulation, and function. Pharmacol Rev 62, 405-496.
-
(2010)
Pharmacol Rev
, vol.62
, pp. 405-496
-
-
Traynelis, S.F.1
Wollmuth, L.P.2
McBain, C.J.3
Menniti, F.S.4
Vance, K.M.5
Ogden, K.K.6
Hansen, K.B.7
Yuan, H.8
Myers, S.J.9
Dingledine, R.10
-
92
-
-
84865635893
-
GluN1 splice variant control of GluN1/GluN2D NMDA receptors
-
Vance KM, Hansen KB & Traynelis SF (2012). GluN1 splice variant control of GluN1/GluN2D NMDA receptors. J Physiol 590, 3857-3875.
-
(2012)
J Physiol
, vol.590
, pp. 3857-3875
-
-
Vance, K.M.1
Hansen, K.B.2
Traynelis, S.F.3
-
93
-
-
12644295056
-
Stable expression and characterization of recombinant human heteromeric N-methyl-d-aspartate receptor subtypes NMDAR1A/2A and NMDAR1A/2B in mammalian cells
-
Varney MA, Jachec C, Deal C, Hess SD, Daggett LP, Skvoretz R, Urcan M, Morrison JH, Moran T, Johnson EC & Velicelebi G (1996). Stable expression and characterization of recombinant human heteromeric N-methyl-d-aspartate receptor subtypes NMDAR1A/2A and NMDAR1A/2B in mammalian cells. J Pharmacol Exp Ther 279, 367-378.
-
(1996)
J Pharmacol Exp Ther
, vol.279
, pp. 367-378
-
-
Varney, M.A.1
Jachec, C.2
Deal, C.3
Hess, S.D.4
Daggett, L.P.5
Skvoretz, R.6
Urcan, M.7
Morrison, J.H.8
Moran, T.9
Johnson, E.C.10
Velicelebi, G.11
-
94
-
-
2642598047
-
Functional and pharmacological differences between recombinant N-methyl-d-aspartate receptors
-
Vicini S, Wang JF, Li JH, Zhu WJ, Wang YH, Luo JH, Wolfe BB & Grayson DR (1998). Functional and pharmacological differences between recombinant N-methyl-d-aspartate receptors. J Neurophysiol 79, 555-566.
-
(1998)
J Neurophysiol
, vol.79
, pp. 555-566
-
-
Vicini, S.1
Wang, J.F.2
Li, J.H.3
Zhu, W.J.4
Wang, Y.H.5
Luo, J.H.6
Wolfe, B.B.7
Grayson, D.R.8
-
95
-
-
0027525324
-
Ifenprodil discriminates subtypes of the N-methyl-d-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors
-
Williams K (1993). Ifenprodil discriminates subtypes of the N-methyl-d-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors. Mol Pharmacol 44, 851-859.
-
(1993)
Mol Pharmacol
, vol.44
, pp. 851-859
-
-
Williams, K.1
-
96
-
-
0030606839
-
Separating dual effects of zinc at recombinant N-methyl-d-aspartate receptors
-
Williams K (1996). Separating dual effects of zinc at recombinant N-methyl-d-aspartate receptors. Neurosci Lett 215, 9-12.
-
(1996)
Neurosci Lett
, vol.215
, pp. 9-12
-
-
Williams, K.1
-
97
-
-
0029071823
-
Structural conservation of ion conduction pathways in K channels and glutamate receptors
-
Wood MW, VanDongen HMA & VanDongen AMJ (1995). Structural conservation of ion conduction pathways in K channels and glutamate receptors. Proc Natl Acad Sci U S A 92, 4882-4886.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 4882-4886
-
-
Wood, M.W.1
VanDongen, H.M.A.2
VanDongen, A.M.J.3
-
98
-
-
37849040160
-
2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes
-
2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. J Physiol 586, 211-225.
-
(2008)
J Physiol
, vol.586
, pp. 211-225
-
-
Wrighton, D.C.1
Baker, E.J.2
Chen, P.E.3
Wyllie, D.J.4
-
99
-
-
0001823013
-
Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors
-
Wyllie DJ, Behe P & Colquhoun D (1998). Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors. J Physiol 510, 1-18.
-
(1998)
J Physiol
, vol.510
, pp. 1-18
-
-
Wyllie, D.J.1
Behe, P.2
Colquhoun, D.3
-
100
-
-
70349610345
-
Control of NMDA receptor function by the NR2 subunit amino-terminal domain
-
Yuan H, Hansen KB, Vance KM, Ogden KK & Traynelis SF (2009). Control of NMDA receptor function by the NR2 subunit amino-terminal domain. J Neurosci 29, 12045-12058.
-
(2009)
J Neurosci
, vol.29
, pp. 12045-12058
-
-
Yuan, H.1
Hansen, K.B.2
Vance, K.M.3
Ogden, K.K.4
Traynelis, S.F.5
-
101
-
-
84905913192
-
Functional analysis of a de novo GRIN2A missense mutation associated with early-onset epileptic encephalopathy
-
Yuan H, Hansen KB, Zhang J, Pierson TM, Markello TC, Fajardo KV, Holloman CM, Golas G, Adams DR, Boerkoel CF, Gahl WA & Traynelis SF (2014). Functional analysis of a de novo GRIN2A missense mutation associated with early-onset epileptic encephalopathy. Nat Commun 5, 3251.
-
(2014)
Nat Commun
, vol.5
, pp. 3251
-
-
Yuan, H.1
Hansen, K.B.2
Zhang, J.3
Pierson, T.M.4
Markello, T.C.5
Fajardo, K.V.6
Holloman, C.M.7
Golas, G.8
Adams, D.R.9
Boerkoel, C.F.10
Gahl, W.A.11
Traynelis, S.F.12
-
102
-
-
84885174557
-
NMDA receptors in nervous system diseases
-
Zhou Q & Sheng M (2013). NMDA receptors in nervous system diseases. Neuropharmacology 74, 69-75.
-
(2013)
Neuropharmacology
, vol.74
, pp. 69-75
-
-
Zhou, Q.1
Sheng, M.2
|