메뉴 건너뛰기




Volumn 55, Issue 6, 1999, Pages 957-969

A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D- aspartate receptor: Effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BINDING PROTEIN; IFENPRODIL; ISOLEUCINE; LEUCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTON; SPERMINE; VALINE;

EID: 0033051714     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.55.6.957     Document Type: Article
Times cited : (143)

References (42)
  • 1
    • 0032578635 scopus 로고    scopus 로고
    • Structure of a glutamate-receptor ligand-binding core in complex with kainate
    • Armstrong N, Sun Y, Chen G-Q and Gouaux E (1998) Structure of a glutamate-receptor ligand-binding core in complex with kainate. Nature (Lond) 395:913-917.
    • (1998) Nature (Lond) , vol.395 , pp. 913-917
    • Armstrong, N.1    Sun, Y.2    Chen, G.-Q.3    Gouaux, E.4
  • 2
    • 0027174665 scopus 로고
    • Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurones
    • Benveniste M and Mayer ML (1993) Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurones. J Physiol (Lond) 464:131-163.
    • (1993) J Physiol (Lond) , vol.464 , pp. 131-163
    • Benveniste, M.1    Mayer, M.L.2
  • 3
    • 0025315206 scopus 로고
    • Ifenprodil and SL 82.0715 as cerebral antiischemic agents. III. Evidence for antagonistic effects at the polyamine modulatory site within the N-methyl-D-aspartate receptor complex
    • Carter CJ, Lloyd KG, Zivkovic B and Scatton B (1990) Ifenprodil and SL 82.0715 as cerebral antiischemic agents. III. Evidence for antagonistic effects at the polyamine modulatory site within the N-methyl-D-aspartate receptor complex. J Pharmacol Exp Ther 253:475-482.
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 475-482
    • Carter, C.J.1    Lloyd, K.G.2    Zivkovic, B.3    Scatton, B.4
  • 5
    • 0027323130 scopus 로고
    • Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C
    • Durand GM, Bennett MVL and Zukin RS (1993) Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C. Proc Natl Acad Sci USA 90:6731-6736.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6731-6736
    • Durand, G.M.1    Bennett, M.V.L.2    Zukin, R.S.3
  • 6
    • 0030803667 scopus 로고    scopus 로고
    • The NR2B-specific interactions of polyamines and protons with the N-methyl-D-aspartate receptor
    • Gallagher MJ, Huang H, Grant ER and Lynch DR (1997) The NR2B-specific interactions of polyamines and protons with the N-methyl-D-aspartate receptor. J Biol Chem 272:24971-24979.
    • (1997) J Biol Chem , vol.272 , pp. 24971-24979
    • Gallagher, M.J.1    Huang, H.2    Grant, E.R.3    Lynch, D.R.4
  • 8
    • 0029945013 scopus 로고    scopus 로고
    • An aspartate residue in the extracellular loop of the N-methyl-D-aspartate receptor controls sensitivity to spermine and protons
    • Kashiwagi K, Fukuchi J, Chao J, Igarashi K and Williams K (1996a) An aspartate residue in the extracellular loop of the N-methyl-D-aspartate receptor controls sensitivity to spermine and protons. Mol Pharmacol 48:1131-1141.
    • (1996) Mol Pharmacol , vol.48 , pp. 1131-1141
    • Kashiwagi, K.1    Fukuchi, J.2    Chao, J.3    Igarashi, K.4    Williams, K.5
  • 9
    • 0030860597 scopus 로고    scopus 로고
    • Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: Role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits
    • Kashiwagi K, Pahk AJ, Masuko T, Igarashi K and Williams K (1997) Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: Role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits. Mol Pharmacol 52:701-713.
    • (1997) Mol Pharmacol , vol.52 , pp. 701-713
    • Kashiwagi, K.1    Pahk, A.J.2    Masuko, T.3    Igarashi, K.4    Williams, K.5
  • 10
    • 15844379305 scopus 로고    scopus 로고
    • Spermidine-preferential uptake system in Escherichia coli. Identification of amino acids involved in polyamine binding in PotD protein
    • Kashiwagi K, Pistocchi R, Shibuya S, Sugiyama S, Morikawa K and Igarashi K (1996b) Spermidine-preferential uptake system in Escherichia coli. Identification of amino acids involved in polyamine binding in PotD protein. J Biol Chem 271:12205-12208.
    • (1996) J Biol Chem , vol.271 , pp. 12205-12208
    • Kashiwagi, K.1    Pistocchi, R.2    Shibuya, S.3    Sugiyama, S.4    Morikawa, K.5    Igarashi, K.6
  • 11
    • 0032190650 scopus 로고    scopus 로고
    • An allosteric interaction between the NMDA receptor polyamine and ifenprodil sites in rat cultured cortical neurones
    • Kew JNC and Kemp JA (1998) An allosteric interaction between the NMDA receptor polyamine and ifenprodil sites in rat cultured cortical neurones. J Physiol (Lond) 512:17-28.
    • (1998) J Physiol (Lond) , vol.512 , pp. 17-28
    • Kew, J.N.C.1    Kemp, J.A.2
  • 12
    • 0030450983 scopus 로고    scopus 로고
    • A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones
    • Kew JNC, Trube G and Kemp JA (1996) A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones. J Physiol (Lond) 497:761-772.
    • (1996) J Physiol (Lond) , vol.497 , pp. 761-772
    • Kew, J.N.C.1    Trube, G.2    Kemp, J.A.3
  • 13
    • 0023613953 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • Kunkel T, Roberts JD and Zakour RA (1987) Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol 154:367-382.
    • (1987) Methods Enzymol , vol.154 , pp. 367-382
    • Kunkel, T.1    Roberts, J.D.2    Zakour, R.A.3
  • 14
    • 0028284469 scopus 로고
    • Mutational analysis of the glycine-binding site of the NMDA receptor: Structural similarity with bacterial amino acid-binding proteins
    • Kuryatov A, Laube B, Betz H and Kuhse J (1994) Mutational analysis of the glycine-binding site of the NMDA receptor: Structural similarity with bacterial amino acid-binding proteins. Neuron 12:1291-1300.
    • (1994) Neuron , vol.12 , pp. 1291-1300
    • Kuryatov, A.1    Laube, B.2    Betz, H.3    Kuhse, J.4
  • 15
    • 0025951641 scopus 로고
    • Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism
    • Legendre P and Westbrook GL (1991) Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism. Mol Pharmacol 40:289-298.
    • (1991) Mol Pharmacol , vol.40 , pp. 289-298
    • Legendre, P.1    Westbrook, G.L.2
  • 16
    • 0025694769 scopus 로고
    • Polyamines potentiate responses of N-methyl-D-aspartate receptors expressed in Xenopus oocytes
    • McGurk JF, Bennett MVL and Zukin RS (1990) Polyamines potentiate responses of N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Proc Natl Acad Sci USA 87:9971-9974.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9971-9974
    • McGurk, J.F.1    Bennett, M.V.L.2    Zukin, R.S.3
  • 20
    • 0030904226 scopus 로고    scopus 로고
    • Assessment of pseudoenergy potentials by the best-five test: A new use of the three-dimensional profiles of proteins
    • Ota M and Nishikawa K (1997) Assessment of pseudoenergy potentials by the best-five test: A new use of the three-dimensional profiles of proteins. Protein Eng 10:339-351.
    • (1997) Protein Eng , vol.10 , pp. 339-351
    • Ota, M.1    Nishikawa, K.2
  • 21
    • 0030899137 scopus 로고    scopus 로고
    • Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes
    • Pahk AJ and Williams K (1997) Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes. Neurosci Lett 225:29-32.
    • (1997) Neurosci Lett , vol.225 , pp. 29-32
    • Pahk, A.J.1    Williams, K.2
  • 22
    • 0024316832 scopus 로고
    • Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: Interaction with polyamines
    • Reynolds IJ and Miller RJ (1989) Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: Interaction with polyamines. Mol Pharmacol 36:758-765.
    • (1989) Mol Pharmacol , vol.36 , pp. 758-765
    • Reynolds, I.J.1    Miller, R.J.2
  • 23
    • 0024563996 scopus 로고
    • Periplasmic binding protein structure and function. Refined X-ray structures of the leucine/isoleucine/valine-binding protein and its complex with leucine
    • Sack JS, Saper MA and Quiocho FA (1989) Periplasmic binding protein structure and function. Refined X-ray structures of the leucine/isoleucine/valine-binding protein and its complex with leucine. J Mol Biol 206:171-191.
    • (1989) J Mol Biol , vol.206 , pp. 171-191
    • Sack, J.S.1    Saper, M.A.2    Quiocho, F.A.3
  • 24
    • 0026737236 scopus 로고
    • Rapid high-efficiency site-directed mutagenesis by the phosphorothioate approach
    • Sayers JR, Krekel C and Eckstein F (1992) Rapid high-efficiency site-directed mutagenesis by the phosphorothioate approach. Biotechniques 13:592-596.
    • (1992) Biotechniques , vol.13 , pp. 592-596
    • Sayers, J.R.1    Krekel, C.2    Eckstein, F.3
  • 25
    • 0031576342 scopus 로고    scopus 로고
    • Xenopus oocytes express a unitary glutamate receptor endogenously
    • Soloviev MM and Barnard EA (1997) Xenopus oocytes express a unitary glutamate receptor endogenously. J Mol Biol 273:14-18.
    • (1997) J Mol Biol , vol.273 , pp. 14-18
    • Soloviev, M.M.1    Barnard, E.A.2
  • 26
    • 0029933361 scopus 로고    scopus 로고
    • Crystal structure of PotD, the primary receptor of the polyamine transport system in Escherichia coli
    • Sugiyama S, Vassylyev DG, Matsushima M, Kashiwagi K, Igarashi K and Morikawa K (1996) Crystal structure of PotD, the primary receptor of the polyamine transport system in Escherichia coli. J Biol Chem 271:9519-9525.
    • (1996) J Biol Chem , vol.271 , pp. 9519-9525
    • Sugiyama, S.1    Vassylyev, D.G.2    Matsushima, M.3    Kashiwagi, K.4    Igarashi, K.5    Morikawa, K.6
  • 27
    • 0028034803 scopus 로고
    • Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor
    • Sullivan JM, Traynelis SF, Chen H-SV, Escobar W, Heinemann SF and Lipton SA (1994) Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor. Neuron 13:929-936.
    • (1994) Neuron , vol.13 , pp. 929-936
    • Sullivan, J.M.1    Traynelis, S.F.2    Chen, H.-S.V.3    Escobar, W.4    Heinemann, S.F.5    Lipton, S.A.6
  • 28
    • 0029966280 scopus 로고    scopus 로고
    • Three-dimensional models of nonNMDA glutamate receptors
    • Sutcliffe MJ, Wo ZG and Oswald RE (1996) Three-dimensional models of nonNMDA glutamate receptors. Biophys J 70:1575-1589.
    • (1996) Biophys J , vol.70 , pp. 1575-1589
    • Sutcliffe, M.J.1    Wo, Z.G.2    Oswald, R.E.3
  • 30
    • 0025142479 scopus 로고
    • Modulation of the N-methyl-D-aspartate channel by extracellular H+
    • Tang CM, Dichter M and Morad M (1990) Modulation of the N-methyl-D-aspartate channel by extracellular H+. Proc Natl Acad Sci USA 87:6445-6449.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6445-6449
    • Tang, C.M.1    Dichter, M.2    Morad, M.3
  • 31
    • 0032529588 scopus 로고    scopus 로고
    • Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit
    • Traynelis SF, Burgess MF, Zheng F, Lyuboslavsky P and Powers JL (1998) Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit. J Neurosci 18:6163-6175.
    • (1998) J Neurosci , vol.18 , pp. 6163-6175
    • Traynelis, S.F.1    Burgess, M.F.2    Zheng, F.3    Lyuboslavsky, P.4    Powers, J.L.5
  • 32
    • 0025350861 scopus 로고
    • Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurones
    • Traynelis SF and Cull-Candy SG (1990) Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurones. Nature (Lond) 245:247-350.
    • (1990) Nature (Lond) , vol.245 , pp. 247-350
    • Traynelis, S.F.1    Cull-Candy, S.G.2
  • 33
    • 0029021010 scopus 로고
    • Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines
    • Traynelis SF, Hartley M and Heinemann SF (1995) Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines. Science (Wash DC) 268:873-876.
    • (1995) Science (Wash DC) , vol.268 , pp. 873-876
    • Traynelis, S.F.1    Hartley, M.2    Heinemann, S.F.3
  • 34
    • 0028921951 scopus 로고
    • Identification of amino acids in the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine binding site
    • Wafford KA, Kathoria M, Bain CJ, Marshall G, LeBourdellès B, Kemp JA and Whiting PJ (1995) Identification of amino acids in the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine binding site. Mol Pharmacol 47:374-380.
    • (1995) Mol Pharmacol , vol.47 , pp. 374-380
    • Wafford, K.A.1    Kathoria, M.2    Bain, C.J.3    Marshall, G.4    LeBourdellès, B.5    Kemp, J.A.6    Whiting, P.J.7
  • 35
    • 0027525324 scopus 로고
    • Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors
    • Williams K (1993) Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors. Mol Pharmacol 44:851-859.
    • (1993) Mol Pharmacol , vol.44 , pp. 851-859
    • Williams, K.1
  • 36
    • 0028069856 scopus 로고
    • Mechanisms influencing stimulatory effects of spermine at recombinant N-methyl-D-aspartate receptors
    • Williams K (1994) Mechanisms influencing stimulatory effects of spermine at recombinant N-methyl-D-aspartate receptors. Mol Pharmacol 46:161-168.
    • (1994) Mol Pharmacol , vol.46 , pp. 161-168
    • Williams, K.1
  • 37
    • 0030853492 scopus 로고    scopus 로고
    • Interactions of polyamines with ion channels
    • Williams K (1997) Interactions of polyamines with ion channels. Biochem J 325: 289-297.
    • (1997) Biochem J , vol.325 , pp. 289-297
    • Williams, K.1
  • 38
    • 0029561009 scopus 로고
    • An acidic amino acid in the N-methyl-D-aspartate receptor that is important for spermine stimulation
    • Williams K, Kashiwagi K, Fukuchi J and Igarashi K (1995) An acidic amino acid in the N-methyl-D-aspartate receptor that is important for spermine stimulation. Mol Pharmacol 48:1087-1098.
    • (1995) Mol Pharmacol , vol.48 , pp. 1087-1098
    • Williams, K.1    Kashiwagi, K.2    Fukuchi, J.3    Igarashi, K.4
  • 40
    • 0027405347 scopus 로고
    • Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro
    • Williams K, Russell SL, Shen YM and Molinoff PB (1993) Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro. Neuron 10:267-278.
    • (1993) Neuron , vol.10 , pp. 267-278
    • Williams, K.1    Russell, S.L.2    Shen, Y.M.3    Molinoff, P.B.4
  • 41
    • 0028340993 scopus 로고
    • Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits
    • Williams K, Zappia AM, Pritchett DB, Shen YM and Molinoff PB (1994) Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits. Mol Pharmacol 45:803-809.
    • (1994) Mol Pharmacol , vol.45 , pp. 803-809
    • Williams, K.1    Zappia, A.M.2    Pritchett, D.B.3    Shen, Y.M.4    Molinoff, P.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.