Berberine protects against neuronal damage via suppression of glia-mediated inflammation in traumatic brain injury

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Chen, Chien G ^a   Hung, Tai Ho ^b   Lee, Chao Yu ^a,d   Wang, Liang Fei ^c   Wu, Chun Hu ^c   Ke, Chia Hua ^a,c   Chen, Szu Fu ^a,c  

^a CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d IQVIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTACOID; BERBERINE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TOLL LIKE RECEPTOR 4; CHEMOKINE; MITOGEN ACTIVATED PROTEIN KINASE; MYD88 PROTEIN, MOUSE; NEUROPROTECTIVE AGENT; TLR4 PROTEIN, MOUSE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN DAMAGE; BRAIN EDEMA; BRAIN WATER; CELL ACTIVATION; DISEASE MODEL; ENZYME ACTIVITY; GLIA CELL; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; MEMBRANE PERMEABILITY; MICROGLIA; MOUSE; NERVE CELL CULTURE; NERVE CELL LESION; NERVE CELL NECROSIS; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRAUMATIC BRAIN INJURY; ANIMAL; BRAIN INJURIES; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; GENETICS; GLIA; INFLAMMATION; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY;

MUS;

ANIMALS; APOPTOSIS; BERBERINE; BLOOD-BRAIN BARRIER; BRAIN INJURIES; CELLS, CULTURED; CHEMOKINES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; NEUROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84919949221     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115694     Document Type: Article

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