Berberine protects against lipopolysaccharide-induced intestinal injury in mice via alpha 2 adrenoceptor-independent mechanisms

Acta Pharmacologica Sinica

Volumn 32, Issue 11, 2011, Pages 1364-1372

  Li, Hong Mei ^a   Wang, Yi Yang ^a   Wang, Hua Dong ^a,b   Cao, Wen Juan ^a   Yu, Xiao Hui ^a   Lu, Da Xiang ^a,b   Qi, Ren Bin ^a,b   Hu, Chao Feng ^a   Yan, Yu Xia ^a  

^a MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

^b JINAN UNIVERSITY   (China)

Author keywords

2 adrenoceptor; apoptosis; berberine; intestinal injury; lipopolysaccharide; macrophage infl ammatory protein 2 (MIP 2); NF B; Toll like receptor 4 (TLR4); yohimbine

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; BERBERINE; I KAPPA B ALPHA; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; MYELOPEROXIDASE; TOLL LIKE RECEPTOR 4; YOHIMBINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTOXEMIA; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; ILEUM; INJURY SCALE; INTESTINE CELL; INTESTINE INJURY; INTESTINE MUCOSA; INTESTINE MUCOSA PERMEABILITY; INTESTINE VILLUS; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NICK END LABELING; NONHUMAN; ORGAN WEIGHT; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BERBERINE; CHEMOKINE CXCL2; DRUGS, CHINESE HERBAL; ENDOTOXEMIA; ENTEROCYTES; GENE EXPRESSION REGULATION; ILEUM; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED BALB C; NEUTROPHILS; NF-KAPPA B; RECEPTORS, ADRENERGIC, ALPHA-2; TOLL-LIKE RECEPTOR 4; YOHIMBINE;

EID: 80755175187     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.102     Document Type: Article

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