Salidroside Improves Behavioral and Histological Outcomes and Reduces Apoptosis via PI3K/Akt Signaling after Experimental Traumatic Brain Injury

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Chen, Szu Fu ^a,b   Tsai, Hsin Ju ^a,b   Hung, Tai Ho ^c   Chen, Chien Cheng ^b   Lee, Chao Yu ^d   Wu, Chun Hu ^a,b   Wang, Pei Yi ^a   Liao, Nien Chieh ^b  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; CYTOCHROME C; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; SALIDROSIDE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN EDEMA; BRAIN WATER; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG DOSE COMPARISON; IN VITRO STUDY; MALE; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRAUMATIC BRAIN INJURY;

ANTIOXIDANTS; APOPTOSIS; BRAIN EDEMA; BRAIN INJURIES; CELLS, CULTURED; CEREBRAL CORTEX; CHROMONES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSIDES; HIPPOCAMPUS; INJECTIONS, INTRAPERITONEAL; MITOCHONDRIA; MORPHOLINES; MOTOR ACTIVITY; NEURONS; NEUROPROTECTIVE AGENTS; ORGAN SPECIFICITY; PHENOLS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; ROTAROD PERFORMANCE TEST; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

MUS;

EID: 84866669157     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045763     Document Type: Article

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