Effect of berberine on cell cycle arrest and cell survival during cerebral ischemia and reperfusion and correlations with p53/cyclin D1 and PI3K/Akt

European Journal of Pharmacology

Volumn 708, Issue 1-3, 2013, Pages 44-55

  Chai, Yu Shuang ^a   Hu, Jun ^a   Lei, Fan ^a   Wang, Yu Gang ^a   Yuan, Zhi Yi ^a   Lu, Xi ^a   Wang, Xin Pei ^a   Du, Feng ^b   Zhang, Dong ^c   Xing, Dong Ming ^a   Du, Li Jun ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b Tulane University   (United States)

^c XIYUAN HOSPITAL   (China)

Author keywords

Berberine; Cell cycle arrest; Cell survival; Cerebral ischemia and reperfusion

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; BERBERINE; CASPASE 3; CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN KINASE B; PROTEIN P53;

AKT GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL CYCLE ARREST; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYCLIN D1 GENE; DOSE RESPONSE; DRUG DOSE COMPARISON; ENZYME ACTIVATION; FEMALE; GENE; GENE EXPRESSION REGULATION; IN VITRO STUDY; IN VIVO STUDY; MALE; NEUROPROTECTION; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PI3K GENE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

ANIMALS; BERBERINE; BRAIN ISCHEMIA; CELL CYCLE CHECKPOINTS; CELL SURVIVAL; CELLS, CULTURED; CYCLIN D1; HIPPOCAMPUS; MALE; MICE; MICE, INBRED ICR; NEURONS; NEUROPROTECTIVE AGENTS; PC12 CELLS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; REPERFUSION INJURY; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84877816985     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.02.041     Document Type: Article

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