Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK-Hep1 cells through the inhibitions of NF-kB and matrix metalloproteinase-2/-9-signaling pathways

Environmental Toxicology

Volumn 30, Issue 1, 2015, Pages 74-82

  Chen, Ya Yin ^a,b   Lu, Hsu Feng ^c   Hsu, Shu Chun ^d   Kuo, Chao Lin ^d   Chang, Shu Jen ^d   Lin, Jen Jyh ^d,e   Wu, Ping Ping ^d   Liu, Jia You ^c   Lee, Ching Hsiao ^f   Chung, Jing Gung ^d,g   Chang, Jin Biou ^h,i  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f JEN TEH JUNIOR COLLEGE OF MEDICINE   (Taiwan)

^g CHINA MEDICAL UNIVERSITY   (Taiwan)

^h TRI SERVICE GENERAL HOSPITAL   (Taiwan)

ⁱ YUANPEI UNIVERSITY   (Taiwan)

Author keywords

Bufalin; Matrix metalloproteinase 2 9; Migration; NF B; SK Hep1

Indexed keywords

CELL CULTURE; DISEASES; PATHOLOGY; PROTEINS; TUMORS;

BUFALIN; HEPATOCELLULAR CARCINOMA; HUMAN CANCER CELLS; MATRIX METALLOPROTEINASE-2; MATRIX METALLOPROTEINASES; MIGRATION; NUCLEAR FACTOR KAPPAB; SK-HEP1;

CELLS;

BUFALIN; FOCAL ADHESION KINASE; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UROKINASE; VASCULOTROPIN; ANTINEOPLASTIC AGENT; BUFADIENOLIDE DERIVATIVE; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BUFO; BUFO GARGARIZANS; BUFO MELANOSTICTUS; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MIGRATION INHIBITION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TUMOR INVASION; ANTAGONISTS AND INHIBITORS; CELL MOTION; DRUG EFFECTS; LIVER TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

BUFO GARGARIZANS; BUFO MELANOSTICTUS;

ANTINEOPLASTIC AGENTS; BUFANOLIDES; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; LIVER NEOPLASMS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; NF-KAPPA B; SIGNAL TRANSDUCTION;

EID: 84919847871     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.21896     Document Type: Article

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