Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways

Environmental Toxicology

Volumn 29, Issue 1, 2014, Pages 21-29

  Chueh, Fu Shin ^a   Chen, Ya Yin ^b,c   Huang, An Cheng ^d   Ho, Heng Chien ^e   Liao, Ching Lung ^e   Yang, Jai Sing ^e   Kuo, Chao Lin ^e   Chung, Jing Gung ^a,e  

^a ASIA UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d St Mary's Medicine Nursing and Management College   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Bufalin; Human osteosarcoma U 2 OS cells; Matrix metalloproteinases; Migration and invasion; Traditional Chinese medicine

Indexed keywords

BUFALIN; HUMAN OSTEOSARCOMA; MATRIX METALLOPROTEINASES; MIGRATION AND INVASION; TRADITIONAL CHINESE MEDICINE;

ASSAYS; CELL CULTURE; CELL DEATH; ENZYME ACTIVITY; ENZYME INHIBITION; PROTEINS;

CELL SIGNALING;

BUFALIN; GELATINASE A; GELATINASE B; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MATRILYSIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; SON OF SEVENLESS HOMOLOG 1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1; UNCLASSIFIED DRUG;

APOPTOSIS; BIOASSAY; CANCER; DISEASE CONTROL; DRUG; ENZYME ACTIVITY; HEALTH CARE; INVASIVE SPECIES; PUBLIC HEALTH; SIGNALING;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ZYMOGRAPHY;

BUFALIN; HUMAN OSTEOSARCOMA U-2 OS CELLS; MATRIX METALLOPROTEINASES; MIGRATION AND INVASION; TRADITIONAL CHINESE MEDICINE;

ANTINEOPLASTIC AGENTS; BONE NEOPLASMS; BUFANOLIDES; CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASE INHIBITORS; NEOPLASM INVASIVENESS; OSTEOSARCOMA; PROTEIN KINASE INHIBITORS;

EID: 84890565131     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20769     Document Type: Article

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