메뉴 건너뛰기




Volumn 232, Issue 11, 2014, Pages 3687-3696

Fingolimod affects gene expression profile associated with LPS-induced memory impairment

Author keywords

FTY720; Gene profiling; Neuroinflammation; Sphingosine 1 phosphate

Indexed keywords

FINGOLIMOD; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; CASPASE 3; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 1BETA; NERVE PROTEIN; PROPANEDIOL DERIVATIVE; SPHINGOSINE; TRANSCRIPTOME; TUMOR NECROSIS FACTOR ALPHA;

EID: 84919847602     PISSN: 00144819     EISSN: 14321106     Source Type: Journal    
DOI: 10.1007/s00221-014-4052-4     Document Type: Article
Times cited : (9)

References (53)
  • 1
    • 79953190058 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking
    • PID: 21173151, COI: 1:CAS:528:DC%2BC3MXisVyqsLk%3D
    • Allende ML, Bektas M, Lee BG, Bonifacino E, Kang J, Tuymetova G, Chen W, Saba JD, Proia RL (2011) Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking. J Biol Chem 286:7348–7358
    • (2011) J Biol Chem , vol.286 , pp. 7348-7358
    • Allende, M.L.1    Bektas, M.2    Lee, B.G.3    Bonifacino, E.4    Kang, J.5    Tuymetova, G.6    Chen, W.7    Saba, J.D.8    Proia, R.L.9
  • 3
    • 0023943181 scopus 로고
    • Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer’s disease
    • PID: 3373218, COI: 1:CAS:528:DyaL1cXktlKjtL0%3D
    • Araujo D, Lapchak P, Robitaille Y, Gauthier S, Quirion R (1988) Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer’s disease. J Neurochem 50:1914–1923
    • (1988) J Neurochem , vol.50 , pp. 1914-1923
    • Araujo, D.1    Lapchak, P.2    Robitaille, Y.3    Gauthier, S.4    Quirion, R.5
  • 5
    • 27844517355 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling
    • PID: 16219683, COI: 1:CAS:528:DC%2BD2MXht1CnurzP
    • Chalfant CE, Spiegel S (2005) Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling. J Cell Sci 118:4605–4612
    • (2005) J Cell Sci , vol.118 , pp. 4605-4612
    • Chalfant, C.E.1    Spiegel, S.2
  • 8
    • 84874431535 scopus 로고    scopus 로고
    • New set of Alzheimer’s trials focus on prevention
    • PID: 23444487
    • Corbyn Z (2013) New set of Alzheimer’s trials focus on prevention. Lancet 381:614–615
    • (2013) Lancet , vol.381 , pp. 614-615
    • Corbyn, Z.1
  • 9
    • 17644365138 scopus 로고    scopus 로고
    • Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs
    • PID: 15771568, COI: 1:CAS:528:DC%2BD2MXktFOjtbg%3D
    • Cyster JG (2005) Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annu Rev Immunol 23:127–159
    • (2005) Annu Rev Immunol , vol.23 , pp. 127-159
    • Cyster, J.G.1
  • 10
    • 77958126430 scopus 로고    scopus 로고
    • B cell follicles and antigen encounters of the third kind
    • PID: 20959804, COI: 1:CAS:528:DC%2BC3cXhtlSgur%2FM
    • Cyster JG (2010) B cell follicles and antigen encounters of the third kind. Nat Immunol 11:989–996
    • (2010) Nat Immunol , vol.11 , pp. 989-996
    • Cyster, J.G.1
  • 12
    • 84865538160 scopus 로고    scopus 로고
    • Fingolimod, a sphingosine-1 phosphate receptor modulator increases BDNF levels and improves symptoms of a mouse model of Rett syndrome
    • PID: 22891354, COI: 1:CAS:528:DC%2BC38XhsVeis77K
    • Deogracias R, Yazdani M, Dekkers MP, Guy J, Ionescu MCS, Vogt KE, Barde Y-A (2012) Fingolimod, a sphingosine-1 phosphate receptor modulator increases BDNF levels and improves symptoms of a mouse model of Rett syndrome. Proc Natl Acad Sci USA 109:14230–14235
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 14230-14235
    • Deogracias, R.1    Yazdani, M.2    Dekkers, M.P.3    Guy, J.4    Ionescu, M.C.S.5    Vogt, K.E.6    Barde, Y.-A.7
  • 13
    • 4444334949 scopus 로고    scopus 로고
    • Influence of a combination of two tetrachlorobiphenyl congeners (PCB 47; PCB 77) on thyroid status, choline acetyltransferase (ChAT) activity, and short-and long-term memory in 30-day-old Sprague–Dawley rats
    • PID: 15363586, COI: 1:CAS:528:DC%2BD2cXnsFGmsrY%3D
    • Donahue DA, Dougherty EJ, Meserve LA (2004) Influence of a combination of two tetrachlorobiphenyl congeners (PCB 47; PCB 77) on thyroid status, choline acetyltransferase (ChAT) activity, and short-and long-term memory in 30-day-old Sprague–Dawley rats. Toxicology 203:99–107
    • (2004) Toxicology , vol.203 , pp. 99-107
    • Donahue, D.A.1    Dougherty, E.J.2    Meserve, L.A.3
  • 14
    • 33748091728 scopus 로고    scopus 로고
    • Effect of lipopolysaccharide on global gene expression in the immature rat brain
    • PID: 16864697, COI: 1:CAS:528:DC%2BD28XntFaksbs%3D
    • Eklind S, Hagberg H, Wang X, Sävman K, Leverin A-L, Hedtjärn M, Mallard C (2006) Effect of lipopolysaccharide on global gene expression in the immature rat brain. Pediatr Res 60:161–168
    • (2006) Pediatr Res , vol.60 , pp. 161-168
    • Eklind, S.1    Hagberg, H.2    Wang, X.3    Sävman, K.4    Leverin, A.-L.5    Hedtjärn, M.6    Mallard, C.7
  • 15
    • 33748047499 scopus 로고    scopus 로고
    • Bioactive sphingolipids in the modulation of the inflammatory response
    • PID: 16759708
    • El Alwani M, Wu BX, Obeid LM, Hannun YA (2006) Bioactive sphingolipids in the modulation of the inflammatory response. Pharmacol Ther 112:171–183
    • (2006) Pharmacol Ther , vol.112 , pp. 171-183
    • El Alwani, M.1    Wu, B.X.2    Obeid, L.M.3    Hannun, Y.A.4
  • 16
    • 84880094451 scopus 로고    scopus 로고
    • Intracranial injection of LPS in rat as animal model of neuroinflammation
    • Espinosa-Oliva AM, de Pablos RM, Herrera AJ (2013) Intracranial injection of LPS in rat as animal model of neuroinflammation. Microglia 1041:295–305
    • (2013) Microglia , vol.1041 , pp. 295-305
    • Espinosa-Oliva, A.M.1    de Pablos, R.M.2    Herrera, A.J.3
  • 17
    • 84859519656 scopus 로고    scopus 로고
    • Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma
    • PID: 22351749, COI: 1:CAS:528:DC%2BC38Xhtl2hsLjO
    • Estrada-Bernal A, Palanichamy K, Chaudhury AR, Van Brocklyn JR (2012) Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma. Neuro-oncology 14:405–415
    • (2012) Neuro-oncology , vol.14 , pp. 405-415
    • Estrada-Bernal, A.1    Palanichamy, K.2    Chaudhury, A.R.3    Van Brocklyn, J.R.4
  • 18
    • 0025782928 scopus 로고
    • Cholinergic mechanisms in learning, memory and dementia: a review of recent evidence
    • PID: 1716012, COI: 1:STN:280:DyaK3MzmtFChtg%3D%3D
    • Fibiger HC (1991) Cholinergic mechanisms in learning, memory and dementia: a review of recent evidence. Trends Neurosci 14:220–223
    • (1991) Trends Neurosci , vol.14 , pp. 220-223
    • Fibiger, H.C.1
  • 20
    • 35348970884 scopus 로고    scopus 로고
    • Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis
    • COI: 1:CAS:528:DC%2BD2sXht1ynsLfP
    • Foster CA, Howard LM, Schweitzer A, Persohn E, Hiestand PC, Balatoni B, Reuschel R, Beerli C, Schwartz M, Billich A (2007) Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis. J Pharmacol Expe Ther 323:469–475
    • (2007) J Pharmacol Expe Ther , vol.323 , pp. 469-475
    • Foster, C.A.1    Howard, L.M.2    Schweitzer, A.3    Persohn, E.4    Hiestand, P.C.5    Balatoni, B.6    Reuschel, R.7    Beerli, C.8    Schwartz, M.9    Billich, A.10
  • 21
    • 84866095781 scopus 로고    scopus 로고
    • Fingolimod (FTY720) inhibits neuroinflammation and attenuates spontaneous convulsions in lithium-pilocarpine induced status epilepticus in rat model
    • PID: 22960129, COI: 1:CAS:528:DC%2BC38Xhs1arurbO
    • Gao F, Liu Y-F, Li X-W, Wang Y, Wei D, Jiang W (2012) Fingolimod (FTY720) inhibits neuroinflammation and attenuates spontaneous convulsions in lithium-pilocarpine induced status epilepticus in rat model. Pharmacol Biochem Behav 103:187–196
    • (2012) Pharmacol Biochem Behav , vol.103 , pp. 187-196
    • Gao, F.1    Liu, Y.-F.2    Li, X.-W.3    Wang, Y.4    Wei, D.5    Jiang, W.6
  • 22
    • 79959515864 scopus 로고    scopus 로고
    • Histology of the central nervous system
    • PID: 21119051
    • Garman RH (2011) Histology of the central nervous system. Toxicol Pathol 39:22–35
    • (2011) Toxicol Pathol , vol.39 , pp. 22-35
    • Garman, R.H.1
  • 23
    • 53949095181 scopus 로고    scopus 로고
    • Ischemic preconditioning induces chaperone hsp70 expression and inhibits protein aggregation in the CA1 neurons of rats
    • PID: 18839022, COI: 1:CAS:528:DC%2BD1MXhtVyrsL7O
    • Ge PF, Luo TF, Zhang JZ, Chen DW, Luan YX, Fu SL (2008) Ischemic preconditioning induces chaperone hsp70 expression and inhibits protein aggregation in the CA1 neurons of rats. Neurosci Bull 24:288–296
    • (2008) Neurosci Bull , vol.24 , pp. 288-296
    • Ge, P.F.1    Luo, T.F.2    Zhang, J.Z.3    Chen, D.W.4    Luan, Y.X.5    Fu, S.L.6
  • 24
    • 84880150760 scopus 로고    scopus 로고
    • Neurorestorative effect of FTY720 in a rat model of Alzheimer’s disease: comparison with memantine
    • PID: 23777795, COI: 1:CAS:528:DC%2BC3sXht1GjsLjL
    • Hemmati F, Dargahi L, Nasoohi S, Omidbakhsh R, Mohamed Z, Naidu M, Ahmadiani A (2013) Neurorestorative effect of FTY720 in a rat model of Alzheimer’s disease: comparison with memantine. Behav Brain Res 252:415–421
    • (2013) Behav Brain Res , vol.252 , pp. 415-421
    • Hemmati, F.1    Dargahi, L.2    Nasoohi, S.3    Omidbakhsh, R.4    Mohamed, Z.5    Naidu, M.6    Ahmadiani, A.7
  • 25
    • 84914155219 scopus 로고    scopus 로고
    • Emerging role of sphingosine-1-phosphate in Inflammation, cancer, and lymphangiogenesis
    • Huang W-C, Nagahashi M, Terracina KP, Takabe K (2013) Emerging role of sphingosine-1-phosphate in Inflammation, cancer, and lymphangiogenesis. Biomolecules 3:408–434
    • (2013) Biomolecules , vol.3 , pp. 408-434
    • Huang, W.-C.1    Nagahashi, M.2    Terracina, K.P.3    Takabe, K.4
  • 27
    • 0030767243 scopus 로고    scopus 로고
    • The cholinergic system in Alzheimer’s disease
    • PID: 9316159
    • Kása P, Rakonczay Z, Gulya K (1997) The cholinergic system in Alzheimer’s disease. Prog Neurobiol 52:511–535
    • (1997) Prog Neurobiol , vol.52 , pp. 511-535
    • Kása, P.1    Rakonczay, Z.2    Gulya, K.3
  • 28
    • 0033199822 scopus 로고    scopus 로고
    • Progressive and gender-dependent cognitive impairment in the APP-transgenic mouse model for Alzheimer’s disease
    • PID: 10513583, COI: 1:STN:280:DyaK1MvktFOnsw%3D%3D
    • King DL, Arendash GW, Crawford F, Sterk T, Menendez J, Mullan MJ (1999) Progressive and gender-dependent cognitive impairment in the APP-transgenic mouse model for Alzheimer’s disease. Behav Brain Res 103:145–162
    • (1999) Behav Brain Res , vol.103 , pp. 145-162
    • King, D.L.1    Arendash, G.W.2    Crawford, F.3    Sterk, T.4    Menendez, J.5    Mullan, M.J.6
  • 29
    • 25644456097 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer’s disease
    • PID: 16192374, COI: 1:CAS:528:DC%2BD2MXhtVOqs7rP
    • Kitazawa M, Oddo S, Yamasaki TR, Green KN, LaFerla FM (2005) Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer’s disease. J Neurosci 25:8843–8853
    • (2005) J Neurosci , vol.25 , pp. 8843-8853
    • Kitazawa, M.1    Oddo, S.2    Yamasaki, T.R.3    Green, K.N.4    LaFerla, F.M.5
  • 30
    • 0023555012 scopus 로고
    • 1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells
    • PID: 3479432, COI: 1:CAS:528:DyaL2sXmtFGntbk%3D
    • Kolesnick RN (1987) 1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells. J Biol Chem 262:16759–16762
    • (1987) J Biol Chem , vol.262 , pp. 16759-16762
    • Kolesnick, R.N.1
  • 31
    • 53349129897 scopus 로고    scopus 로고
    • Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation
    • Lee JW, Lee YK, Yuk DY, Choi DY, Ban SB, Oh KW, Hong JT (2008) Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation. J Neuroinflamm 5:37–51
    • (2008) J Neuroinflamm , vol.5 , pp. 37-51
    • Lee, J.W.1    Lee, Y.K.2    Yuk, D.Y.3    Choi, D.Y.4    Ban, S.B.5    Oh, K.W.6    Hong, J.T.7
  • 33
    • 79951649767 scopus 로고    scopus 로고
    • The regulatory mechanism of melanogenesis by FTY720, a sphingolipid analogue
    • PID: 21166720, COI: 1:CAS:528:DC%2BC3MXktlylsbc%3D
    • Lee JE, Kim SY, Jeong YM, Yun HY, Baek KJ, Kwon NS, Park KC, Kim DS (2011) The regulatory mechanism of melanogenesis by FTY720, a sphingolipid analogue. Exp Dermatol 20:237–241
    • (2011) Exp Dermatol , vol.20 , pp. 237-241
    • Lee, J.E.1    Kim, S.Y.2    Jeong, Y.M.3    Yun, H.Y.4    Baek, K.J.5    Kwon, N.S.6    Park, K.C.7    Kim, D.S.8
  • 34
    • 0036513485 scopus 로고    scopus 로고
    • The molecular basis of CaMKII function in synaptic and behavioural memory
    • PID: 11994750, COI: 1:CAS:528:DC%2BD38Xit1GrtLk%3D
    • Lisman J, Schulman H, Cline H (2002) The molecular basis of CaMKII function in synaptic and behavioural memory. Nat Rev Neurosci 3:175–190
    • (2002) Nat Rev Neurosci , vol.3 , pp. 175-190
    • Lisman, J.1    Schulman, H.2    Cline, H.3
  • 35
    • 58149401211 scopus 로고    scopus 로고
    • CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages
    • PID: 18818394, COI: 1:CAS:528:DC%2BD1cXhsFWms73N
    • Liu X, Yao M, Li N, Wang C, Zheng Y, Cao X (2008) CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages. Blood 112:4961–4970
    • (2008) Blood , vol.112 , pp. 4961-4970
    • Liu, X.1    Yao, M.2    Li, N.3    Wang, C.4    Zheng, Y.5    Cao, X.6
  • 37
    • 0033559508 scopus 로고    scopus 로고
    • Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway
    • PID: 10092785, COI: 1:CAS:528:DyaK1MXhvV2rtbs%3D
    • Matsuda S, Minowa A, Suzuki S, Koyasu S (1999) Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway. J Immunol 162:3321–3326
    • (1999) J Immunol , vol.162 , pp. 3321-3326
    • Matsuda, S.1    Minowa, A.2    Suzuki, S.3    Koyasu, S.4
  • 38
    • 79955856733 scopus 로고    scopus 로고
    • JNK: a stress-activated protein kinase therapeutic strategies and involvement in Alzheimer’s and various neurodegenerative abnormalities
    • PID: 20878262, COI: 1:CAS:528:DC%2BC3MXit1KiurY%3D
    • Mehan S, Meena H, Sharma D, Sankhla R (2011) JNK: a stress-activated protein kinase therapeutic strategies and involvement in Alzheimer’s and various neurodegenerative abnormalities. J Mol Neurosci 43:376–390
    • (2011) J Mol Neurosci , vol.43 , pp. 376-390
    • Mehan, S.1    Meena, H.2    Sharma, D.3    Sankhla, R.4
  • 39
    • 53049085954 scopus 로고    scopus 로고
    • Central nervous system-directed effects of FTY720 (fingolimod)
    • PID: 18678377, COI: 1:CAS:528:DC%2BD1cXht1eitr3P
    • Miron VE, Schubart A, Antel JP (2008) Central nervous system-directed effects of FTY720 (fingolimod). J Neurol Sci 274:13–17
    • (2008) J Neurol Sci , vol.274 , pp. 13-17
    • Miron, V.E.1    Schubart, A.2    Antel, J.P.3
  • 40
    • 0347914568 scopus 로고    scopus 로고
    • Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction
    • PID: 14729126, COI: 1:CAS:528:DC%2BD2cXjsFSktA%3D%3D
    • Mufson EJ, Ginsberg SD, Ikonomovic MD, DeKosky ST (2003) Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction. J Chem Neuroanat 26:233–242
    • (2003) J Chem Neuroanat , vol.26 , pp. 233-242
    • Mufson, E.J.1    Ginsberg, S.D.2    Ikonomovic, M.D.3    DeKosky, S.T.4
  • 41
    • 84875367110 scopus 로고    scopus 로고
    • Fingolimod phosphate promotes the neuroprotective effects of microglia
    • PID: 23290828, COI: 1:CAS:528:DC%2BC3sXjvFWhsg%3D%3D
    • Noda H, Takeuchi H, Mizuno T, Suzumura A (2013) Fingolimod phosphate promotes the neuroprotective effects of microglia. J Neuroimmunol 256:13–18
    • (2013) J Neuroimmunol , vol.256 , pp. 13-18
    • Noda, H.1    Takeuchi, H.2    Mizuno, T.3    Suzumura, A.4
  • 42
    • 0034785791 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases and cerebral ischemia
    • PID: 11642541, COI: 1:CAS:528:DC%2BD3MXnvFeht74%3D
    • Nozaki K, Nishimura M, Hashimoto N (2001) Mitogen-activated protein kinases and cerebral ischemia. Mol Neurobiol 23:1–19
    • (2001) Mol Neurobiol , vol.23 , pp. 1-19
    • Nozaki, K.1    Nishimura, M.2    Hashimoto, N.3
  • 43
    • 0024795059 scopus 로고
    • Sphingomyelin turnover induced by vitamin D3 in HL-60 cells Role in cell differentiation
    • PID: 2808413, COI: 1:CAS:528:DyaL1MXmtV2ksLY%3D
    • Okazaki T, Bell R, Hannun Y (1989) Sphingomyelin turnover induced by vitamin D3 in HL-60 cells Role in cell differentiation. J Biol Chem 264:19076–19080
    • (1989) J Biol Chem , vol.264 , pp. 19076-19080
    • Okazaki, T.1    Bell, R.2    Hannun, Y.3
  • 44
    • 33745679123 scopus 로고    scopus 로고
    • Targeting signal transduction as a strategy to treat inflammatory diseases
    • PID: 16773072
    • O’Neill LA (2006) Targeting signal transduction as a strategy to treat inflammatory diseases. Nat Rev Drug Discov 5:549–563
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 549-563
    • O’Neill, L.A.1
  • 45
    • 0034659815 scopus 로고    scopus 로고
    • Proteomics to study genes and genomes
    • PID: 10866210, COI: 1:CAS:528:DC%2BD3cXksV2jt74%3D
    • Pandey A, Mann M (2000) Proteomics to study genes and genomes. Nature 405:837–846
    • (2000) Nature , vol.405 , pp. 837-846
    • Pandey, A.1    Mann, M.2
  • 46
    • 40749112792 scopus 로고    scopus 로고
    • Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10
    • PID: 18174455, COI: 1:CAS:528:DC%2BD1cXit1OlsbY%3D
    • Pereira C, Schaer DJ, Bachli EB, Kurrer MO, Schoedon G (2008) Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10. Arterioscler Thromb Vasc Biol 28:504–510
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 504-510
    • Pereira, C.1    Schaer, D.J.2    Bachli, E.B.3    Kurrer, M.O.4    Schoedon, G.5
  • 47
    • 52949108813 scopus 로고    scopus 로고
    • The alliance of sphingosine-1-phosphate and its receptors in immunity
    • PID: 18787560, COI: 1:CAS:528:DC%2BD1cXhtFKkur%2FI
    • Rivera J, Proia RL, Olivera A (2008) The alliance of sphingosine-1-phosphate and its receptors in immunity. Nat Rev Immunol 8:753–763
    • (2008) Nat Rev Immunol , vol.8 , pp. 753-763
    • Rivera, J.1    Proia, R.L.2    Olivera, A.3
  • 48
    • 0032549658 scopus 로고    scopus 로고
    • Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of IFN-β gene
    • PID: 9541017, COI: 1:CAS:528:DyaK1cXhs1Gisrg%3D
    • Sato M, Tanaka N, Hata N, Oda E, Taniguchi T (1998) Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of IFN-β gene. FEBS Lett 425:112–116
    • (1998) FEBS Lett , vol.425 , pp. 112-116
    • Sato, M.1    Tanaka, N.2    Hata, N.3    Oda, E.4    Taniguchi, T.5
  • 49
    • 0035016261 scopus 로고    scopus 로고
    • Lipopolysaccharide induces memory-processing deficits in day-old chicks
    • PID: 11325404, COI: 1:CAS:528:DC%2BD3MXivFensbw%3D
    • Sell KM, Crowe SF, Kent S (2001) Lipopolysaccharide induces memory-processing deficits in day-old chicks. Pharmacol Biochem Behav 68:497–502
    • (2001) Pharmacol Biochem Behav , vol.68 , pp. 497-502
    • Sell, K.M.1    Crowe, S.F.2    Kent, S.3
  • 50
    • 84862880013 scopus 로고    scopus 로고
    • Sesaminol glucosides protect β-amyloid induced apoptotic cell death by regulating redox system in SK-N-SH
    • COI: 1:CAS:528:DC%2BC3MXhsFOnsbvI
    • Um MY, Ahn JY, Kim MK, Ha TY (2012) Sesaminol glucosides protect β-amyloid induced apoptotic cell death by regulating redox system in SK-N-SH. Cells Neurochem Res 37:689–699
    • (2012) Cells Neurochem Res , vol.37 , pp. 689-699
    • Um, M.Y.1    Ahn, J.Y.2    Kim, M.K.3    Ha, T.Y.4
  • 51
    • 78649465795 scopus 로고    scopus 로고
    • Toll-like receptor tolerance as a mechanism for neuroprotection
    • PID: 21339866, COI: 1:CAS:528:DC%2BC3cXhsVCms7bP
    • Vartanian KB, Stenzel-Poore MP (2010) Toll-like receptor tolerance as a mechanism for neuroprotection. Transl Stroke Res 1:252–260
    • (2010) Transl Stroke Res , vol.1 , pp. 252-260
    • Vartanian, K.B.1    Stenzel-Poore, M.P.2
  • 52
    • 77956209928 scopus 로고    scopus 로고
    • Why women have more Alzheimer’s disease than men: gender and mitochondrial toxicity of amyloid-β peptide
    • Viña J, Lloret A (2010) Why women have more Alzheimer’s disease than men: gender and mitochondrial toxicity of amyloid-β peptide. J Alzheimers Dis 20:527–533
    • (2010) J Alzheimers Dis , vol.20 , pp. 527-533
    • Viña, J.1    Lloret, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.