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Volumn 9, Issue 6, 2014, Pages 2219-2232

Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOKINASE; INSULIN; NEUROGENIN 3; PROTEIN RFX6; SULFONYLUREA RECEPTOR 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; ABCC8 PROTEIN, MOUSE; CALCIUM CHANNEL; DNA BINDING PROTEIN; GLUCOSE; RFX6 PROTEIN, MOUSE; SULFONYLUREA RECEPTOR;

EID: 84919846858     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.11.033     Document Type: Article
Times cited : (111)

References (56)
  • 1
    • 51649112751 scopus 로고    scopus 로고
    • Identification and characterization of novel human tissue-specific RFX transcription factors
    • Aftab S., Semenec L., Chu J.S., Chen N. Identification and characterization of novel human tissue-specific RFX transcription factors. BMC Evol. Biol. 2008, 8:226.
    • (2008) BMC Evol. Biol. , vol.8 , pp. 226
    • Aftab, S.1    Semenec, L.2    Chu, J.S.3    Chen, N.4
  • 2
    • 0033919717 scopus 로고    scopus 로고
    • Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion
    • Ainscow E.K., Zhao C., Rutter G.A. Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion. Diabetes 2000, 49:1149-1155.
    • (2000) Diabetes , vol.49 , pp. 1149-1155
    • Ainscow, E.K.1    Zhao, C.2    Rutter, G.A.3
  • 5
    • 84857975722 scopus 로고    scopus 로고
    • Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3
    • Blum B., Hrvatin S.S., Schuetz C., Bonal C., Rezania A., Melton D.A. Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3. Nat. Biotechnol. 2012, 30:261-264.
    • (2012) Nat. Biotechnol. , vol.30 , pp. 261-264
    • Blum, B.1    Hrvatin, S.S.2    Schuetz, C.3    Bonal, C.4    Rezania, A.5    Melton, D.A.6
  • 6
    • 0037219411 scopus 로고    scopus 로고
    • Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
    • Butler A.E., Janson J., Bonner-Weir S., Ritzel R., Rizza R.A., Butler P.C. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003, 52:102-110.
    • (2003) Diabetes , vol.52 , pp. 102-110
    • Butler, A.E.1    Janson, J.2    Bonner-Weir, S.3    Ritzel, R.4    Rizza, R.A.5    Butler, P.C.6
  • 8
    • 84893646612 scopus 로고    scopus 로고
    • Neonatal diabetes, gallbladder agenesis, duodenal atresia, and intestinal malrotation caused by a novel homozygous mutation in RFX6
    • Concepcion J.P., Reh C.S., Daniels M., Liu X., Paz V.P., Ye H., Highland H.M., Hanis C.L., Greeley S.A. Neonatal diabetes, gallbladder agenesis, duodenal atresia, and intestinal malrotation caused by a novel homozygous mutation in RFX6. Pediatr. Diabetes 2014, 15:67-72.
    • (2014) Pediatr. Diabetes , vol.15 , pp. 67-72
    • Concepcion, J.P.1    Reh, C.S.2    Daniels, M.3    Liu, X.4    Paz, V.P.5    Ye, H.6    Highland, H.M.7    Hanis, C.L.8    Greeley, S.A.9
  • 9
    • 84897452599 scopus 로고    scopus 로고
    • Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion
    • Dayeh T., Volkov P., Salö S., Hall E., Nilsson E., Olsson A.H., Kirkpatrick C.L., Wollheim C.B., Eliasson L., Rönn T., et al. Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion. PLoS Genet. 2014, 10:e1004160.
    • (2014) PLoS Genet. , vol.10 , pp. e1004160
    • Dayeh, T.1    Volkov, P.2    Salö, S.3    Hall, E.4    Nilsson, E.5    Olsson, A.H.6    Kirkpatrick, C.L.7    Wollheim, C.B.8    Eliasson, L.9    Rönn, T.10
  • 12
    • 84872248207 scopus 로고    scopus 로고
    • The developmental regulator Pax6 is essential for maintenance of islet cell function in the adult mouse pancreas
    • Hart A.W., Mella S., Mendrychowski J., van Heyningen V., Kleinjan D.A. The developmental regulator Pax6 is essential for maintenance of islet cell function in the adult mouse pancreas. PLoS ONE 2013, 8:e54173.
    • (2013) PLoS ONE , vol.8 , pp. e54173
    • Hart, A.W.1    Mella, S.2    Mendrychowski, J.3    van Heyningen, V.4    Kleinjan, D.A.5
  • 16
    • 0033431775 scopus 로고    scopus 로고
    • Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells
    • Ishihara H., Wang H., Drewes L.R., Wollheim C.B. Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells. J.Clin. Invest. 1999, 104:1621-1629.
    • (1999) J.Clin. Invest. , vol.104 , pp. 1621-1629
    • Ishihara, H.1    Wang, H.2    Drewes, L.R.3    Wollheim, C.B.4
  • 17
    • 0027186032 scopus 로고
    • Mammalian glucokinase and its gene
    • Iynedjian P.B. Mammalian glucokinase and its gene. Biochem. J. 1993, 293:1-13.
    • (1993) Biochem. J. , vol.293 , pp. 1-13
    • Iynedjian, P.B.1
  • 20
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B., Trapnell C., Pop M., Salzberg S.L. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 2009, 10:R25.
    • (2009) Genome Biol. , vol.10 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 21
    • 34247279657 scopus 로고    scopus 로고
    • Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis
    • Li C., Chen P., Vaughan J., Lee K.-F., Vale W. Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis. Proc. Natl. Acad. Sci. USA 2007, 104:4206-4211.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 4206-4211
    • Li, C.1    Chen, P.2    Vaughan, J.3    Lee, K.-F.4    Vale, W.5
  • 23
    • 77955364191 scopus 로고    scopus 로고
    • Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes
    • Marselli L., Thorne J., Dahiya S., Sgroi D.C., Sharma A., Bonner-Weir S., Marchetti P., Weir G.C. Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes. PLoS ONE 2010, 5:e11499.
    • (2010) PLoS ONE , vol.5 , pp. e11499
    • Marselli, L.1    Thorne, J.2    Dahiya, S.3    Sgroi, D.C.4    Sharma, A.5    Bonner-Weir, S.6    Marchetti, P.7    Weir, G.C.8
  • 25
    • 23844433186 scopus 로고    scopus 로고
    • Glucokinase, glucose homeostasis, and diabetes mellitus
    • Matschinsky F.M. Glucokinase, glucose homeostasis, and diabetes mellitus. Curr. Diab. Rep. 2005, 5:171-176.
    • (2005) Curr. Diab. Rep. , vol.5 , pp. 171-176
    • Matschinsky, F.M.1
  • 26
    • 77956282569 scopus 로고    scopus 로고
    • The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet
    • McTaggart J.S., Clark R.H., Ashcroft F.M. The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet. J.Physiol. 2010, 588:3201-3209.
    • (2010) J.Physiol. , vol.588 , pp. 3201-3209
    • McTaggart, J.S.1    Clark, R.H.2    Ashcroft, F.M.3
  • 27
    • 19944431807 scopus 로고    scopus 로고
    • Neonatal diabetes, with hypoplastic pancreas, intestinal atresia and gall bladder hypoplasia: search forthe aetiology of a new autosomal recessive syndrome
    • Mitchell J., Punthakee Z., Lo B., Bernard C., Chong K., Newman C., Cartier L., Desilets V., Cutz E., Hansen I.L., et al. Neonatal diabetes, with hypoplastic pancreas, intestinal atresia and gall bladder hypoplasia: search forthe aetiology of a new autosomal recessive syndrome. Diabetologia 2004, 47:2160-2167.
    • (2004) Diabetologia , vol.47 , pp. 2160-2167
    • Mitchell, J.1    Punthakee, Z.2    Lo, B.3    Bernard, C.4    Chong, K.5    Newman, C.6    Cartier, L.7    Desilets, V.8    Cutz, E.9    Hansen, I.L.10
  • 28
    • 3542993224 scopus 로고    scopus 로고
    • Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells
    • Nenquin M., Szollosi A., Aguilar-Bryan L., Bryan J., Henquin J.C. Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells. J.Biol. Chem. 2004, 279:32316-32324.
    • (2004) J.Biol. Chem. , vol.279 , pp. 32316-32324
    • Nenquin, M.1    Szollosi, A.2    Aguilar-Bryan, L.3    Bryan, J.4    Henquin, J.C.5
  • 30
    • 79551686759 scopus 로고    scopus 로고
    • Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes
    • Pearl E.J., Jarikji Z., Horb M.E. Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes. Dev. Biol. 2011, 351:135-145.
    • (2011) Dev. Biol. , vol.351 , pp. 135-145
    • Pearl, E.J.1    Jarikji, Z.2    Horb, M.E.3
  • 31
    • 84877601932 scopus 로고    scopus 로고
    • When less is more: the forbidden fruits of gene repression in the adult β-cell
    • Pullen T.J., Rutter G.A. When less is more: the forbidden fruits of gene repression in the adult β-cell. Diabetes Obes. Metab. 2013, 15:503-512.
    • (2013) Diabetes Obes. Metab. , vol.15 , pp. 503-512
    • Pullen, T.J.1    Rutter, G.A.2
  • 32
  • 33
    • 79960322580 scopus 로고    scopus 로고
    • MiR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1)
    • Pullen T.J., da Silva Xavier G., Kelsey G., Rutter G.A. miR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1). Mol. Cell. Biol. 2011, 31:3182-3194.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 3182-3194
    • Pullen, T.J.1    da Silva Xavier, G.2    Kelsey, G.3    Rutter, G.A.4
  • 34
    • 84863214806 scopus 로고    scopus 로고
    • Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic β-cells leads to relative hyperinsulinism during exercise
    • Pullen T.J., Sylow L., Sun G., Halestrap A.P., Richter E.A., Rutter G.A. Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic β-cells leads to relative hyperinsulinism during exercise. Diabetes 2012, 61:1719-1725.
    • (2012) Diabetes , vol.61 , pp. 1719-1725
    • Pullen, T.J.1    Sylow, L.2    Sun, G.3    Halestrap, A.P.4    Richter, E.A.5    Rutter, G.A.6
  • 38
    • 12144281012 scopus 로고    scopus 로고
    • Visualising insulin secretion. The Minkowski Lecture 2004
    • Rutter G.A. Visualising insulin secretion. The Minkowski Lecture 2004. Diabetologia 2004, 47:1861-1872.
    • (2004) Diabetologia , vol.47 , pp. 1861-1872
    • Rutter, G.A.1
  • 39
    • 77953399221 scopus 로고    scopus 로고
    • Think zinc: new roles for zinc in the control of insulin secretion
    • Rutter G.A. Think zinc: new roles for zinc in the control of insulin secretion. Islets 2010, 2:49-50.
    • (2010) Islets , vol.2 , pp. 49-50
    • Rutter, G.A.1
  • 40
    • 84910625084 scopus 로고    scopus 로고
    • Dorothy Hodgkin Lecture 2014. Understanding genes identified by genome-wide association studies for type 2 diabetes
    • Rutter G.A. Dorothy Hodgkin Lecture 2014. Understanding genes identified by genome-wide association studies for type 2 diabetes. Diabet. Med. 2014, 31:1480-1487.
    • (2014) Diabet. Med. , vol.31 , pp. 1480-1487
    • Rutter, G.A.1
  • 45
    • 80054923598 scopus 로고    scopus 로고
    • Clinical characterization of a newly described neonatal diabetes syndrome caused by RFX6 mutations
    • Spiegel R., Dobbie A., Hartman C., de Vries L., Ellard S., Shalev S.A. Clinical characterization of a newly described neonatal diabetes syndrome caused by RFX6 mutations. Am. J. Med. Genet. 2011, 155A:2821-2825.
    • (2011) Am. J. Med. Genet. , vol.155 A , pp. 2821-2825
    • Spiegel, R.1    Dobbie, A.2    Hartman, C.3    de Vries, L.4    Ellard, S.5    Shalev, S.A.6
  • 46
    • 84866389264 scopus 로고    scopus 로고
    • Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure
    • Talchai C., Xuan S., Lin H.V., Sussel L., Accili D. Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell 2012, 150:1223-1234.
    • (2012) Cell , vol.150 , pp. 1223-1234
    • Talchai, C.1    Xuan, S.2    Lin, H.V.3    Sussel, L.4    Accili, D.5
  • 49
    • 84884590826 scopus 로고    scopus 로고
    • Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells
    • Taylor B.L., Liu F.-F., Sander M. Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells. Cell Rep. 2013, 4:1262-1275.
    • (2013) Cell Rep. , vol.4 , pp. 1262-1275
    • Taylor, B.L.1    Liu, F.-F.2    Sander, M.3
  • 50
    • 0029417331 scopus 로고
    • Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose
    • Terauchi Y., Sakura H., Yasuda K., Iwamoto K., Takahashi N., Ito K., Kasai H., Suzuki H., Ueda O., Kamada N., et al. Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose. J.Biol. Chem. 1995, 270:30253-30256.
    • (1995) J.Biol. Chem. , vol.270 , pp. 30253-30256
    • Terauchi, Y.1    Sakura, H.2    Yasuda, K.3    Iwamoto, K.4    Takahashi, N.5    Ito, K.6    Kasai, H.7    Suzuki, H.8    Ueda, O.9    Kamada, N.10
  • 52
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Seq
    • Trapnell C., Pachter L., Salzberg S.L. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 2009, 25:1105-1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 54
    • 33750067680 scopus 로고    scopus 로고
    • The role of voltage-gated calcium channels in pancreatic beta-cell physiology and pathophysiology
    • Yang S.N., Berggren P.O. The role of voltage-gated calcium channels in pancreatic beta-cell physiology and pathophysiology. Endocr. Rev. 2006, 27:621-676.
    • (2006) Endocr. Rev. , vol.27 , pp. 621-676
    • Yang, S.N.1    Berggren, P.O.2


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