Antioxidant catalase rescues against high fat diet-induced cardiac dysfunction via an IKKβ-AMPK-dependent regulation of autophagy

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 2, 2015, Pages 343-352

  Liang, Lei ^a,b   Shou, Xi Ling ^a,b   Zhao, Hai Kang ^c   Ren, Gu qun ^c   Wang, Jian Bang ^c   Wang, Xi Hui ^c   Ai, Wen Ting ^b   Maris, Jackie R ^d   Hueckstaedt, Lindsay K ^d   Ma, Ai qun ^b   Zhang, Yingmei ^d  

^a SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

^c XI'AN MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF WYOMING COLLEGE OF HEALTH SCIENCES   (United States)

Author keywords

AMPK; Autophagy; Cardiomyocyte; Catalase; Fat diet; IKK

Indexed keywords

CATALASE; FURA 2 ACETOXYMETHYL ESTER; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; I KAPPA B KINASE BETA; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; SALICYLATE SODIUM; TUBERIN; ANTIOXIDANT; CALCIUM; I KAPPA B KINASE;

ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FAT INTAKE; GENE OVEREXPRESSION; GEOMETRY; GLUCOSE BLOOD LEVEL; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART LEFT VENTRICLE SIZE; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HYPERINSULINEMIA; HYPERTRIGLYCERIDEMIA; INSULIN BLOOD LEVEL; LIPID DIET; LOW FAT DIET; MALE; MOUSE; NONHUMAN; OBESITY; TRANSGENE; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; BIOLOGICAL MODEL; CARDIOMEGALY; DRUG EFFECTS; ECHOCARDIOGRAPHY; ENZYMOLOGY; FEEDING BEHAVIOR; HEART; HEART CONTRACTION; INTRACELLULAR SPACE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION;

MUS MUSCULUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIOXIDANTS; AUTOPHAGY; CALCIUM; CARDIOMEGALY; CATALASE; DIET, HIGH-FAT; ECHOCARDIOGRAPHY; FEEDING BEHAVIOR; HEART; I-KAPPA B KINASE; INTRACELLULAR SPACE; MALE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MYOCARDIAL CONTRACTION; PALMITIC ACID; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84919830272     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.06.027     Document Type: Article

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