Inactivation of Bcl-2 through IκB kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE)

Journal of Cellular Physiology

Volumn 227, Issue 11, 2012, Pages 3556-3565

  Bodur, Cagri ^a   Kutuk, Ozgur ^a   Tezil, Tugsan ^a   Basaga, Huveyda ^a  

^a SABANCI UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BAK; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; SMALL INTERFERING RNA;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; DRUG EXPOSURE; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE INACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPID PEROXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION;

ALDEHYDES; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; I-KAPPA B KINASE; MACROPHAGES; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; U937 CELLS;

MAMMALIA;

EID: 84864081330     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24057     Document Type: Article

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