Progression from compensated hypertrophy to failure in the pressure-overloaded human: Heart structural deterioration and compensatory mechanisms

Circulation

Volumn 107, Issue 7, 2003, Pages 984-991

  Hein, Stefan ^a   Arnon, Eyal ^b   Kostin, Sawa ^b   Schönburg, Markus ^a   Elsässer, Albrecht ^c   Polyakova, Victoria ^b   Bauer, Erwin P ^a   Klövekorn, Wolf Peter ^a   Schaper, Jutta ^b  

^a KERCKHOFF HEART CENTER   (Germany)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Heart failure; Hemodynamics; Hypertrophy; Remodeling; Structure

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CELL NUCLEUS DNA; DIGITALIS; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; TRANSFORMING GROWTH FACTOR BETA;

ADULT; AGED; AORTA STENOSIS; AORTA VALVE REPLACEMENT; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL DEGENERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DNA SYNTHESIS; FEMALE; HEART EJECTION FRACTION; HEART FAILURE; HEART HYPERTROPHY; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; HEMODYNAMICS; HUMAN; HUMAN TISSUE; MALE; MITOSIS; MUSCLE RESECTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; UPREGULATION;

AGED; AORTIC VALVE STENOSIS; CAPILLARIES; CARDIOMEGALY; CELL DEATH; CELL NUCLEUS; DISEASE PROGRESSION; DNA; FEMALE; FIBROSIS; HEART FAILURE, CONGESTIVE; HEMODYNAMIC PROCESSES; HUMANS; INFLAMMATION; MALE; MODELS, CARDIOVASCULAR; MYOCYTES, CARDIAC; NUCLEAR PROTEINS; PEPTIDYL-DIPEPTIDASE A; RIBONUCLEOPROTEINS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 0037465434     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000051865.66123.B7     Document Type: Article

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