-
1
-
-
79959517565
-
Human fatty liver disease: Old questions and new insights
-
PMID: 21700865
-
Cohen JC, Horton JD, Hobbs HH. Human fatty liver disease: old questions and new insights. Science 2011; 332: 1519-1523 [PMID: 21700865 DOI: 10.1126/science.1204265]
-
(2011)
Science
, vol.332
, pp. 1519-1523
-
-
Cohen, J.C.1
Horton, J.D.2
Hobbs, H.H.3
-
2
-
-
80053088189
-
Hepatocellular carcinoma
-
PMID: 21992124
-
El-Serag HB. Hepatocellular carcinoma. N Engl J Med 2011; 365 : 1118-1127 [PMID: 21992124 DOI: 10.1056/NEJMra1001683]
-
(2011)
N Engl J Med
, vol.365
, pp. 1118-1127
-
-
El-Serag, H.B.1
-
3
-
-
84898732247
-
Fatty acid elongation in nonalcoholic steatohepatitis and hepatocellular carcinoma
-
PMID: 24714086
-
Kessler SM, Simon Y, Gemperlein K, Gianmoena K, Cadenas C, Zimmer V, Pokorny J, Barghash A, Helms V, van Rooijen N, Bohle RM, Lammert F, Hengstler JG, Mueller R, Haybaeck J, Kiemer AK. Fatty acid elongation in nonalcoholic steatohepatitis and hepatocellular carcinoma. Int J Mol Sci 2014; 15: 5762-5773 [PMID: 24714086 DOI: 10.3390/ ijms15045762]
-
(2014)
Int J Mol Sci
, vol.15
, pp. 5762-5773
-
-
Kessler, S.M.1
Simon, Y.2
Gemperlein, K.3
Gianmoena, K.4
Cadenas, C.5
Zimmer, V.6
Pokorny, J.7
Barghash, A.8
Helms, V.9
Van Rooijen, N.10
Bohle, R.M.11
Lammert, F.12
Hengstler, J.G.13
Mueller, R.14
Haybaeck, J.15
Kiemer, A.K.16
-
4
-
-
84887323587
-
Rapid chromatographic method to decipher distinct alterations in lipid classes in NAFLD/NASH
-
PMID: 24179615
-
Laggai S, Simon Y, Ranssweiler T, Kiemer AK, Kessler SM. Rapid chromatographic method to decipher distinct alterations in lipid classes in NAFLD/NASH. World J Hepatol 2013; 5: 558-567 [PMID: 24179615 DOI: 10.4254/wjh.v5.i10.558]
-
(2013)
World J Hepatol
, vol.5
, pp. 558-567
-
-
Laggai, S.1
Simon, Y.2
Ranssweiler, T.3
Kiemer, A.K.4
Kessler, S.M.5
-
5
-
-
84901649725
-
The IGF2 mRNA binding protein p62/ IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis
-
PMID: 24755648
-
Laggai S, Kessler SM, Boettcher S, Lebrun V, Gemperlein K, Lederer E, Leclercq IA, Mueller R, Hartmann RW, Haybaeck J, Kiemer AK. The IGF2 mRNA binding protein p62/ IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis. J Lipid Res 2014; 55: 1087-1097 [PMID: 24755648 DOI: 10.1194/jlr.M045500]
-
(2014)
J Lipid Res
, vol.55
, pp. 1087-1097
-
-
Laggai, S.1
Kessler, S.M.2
Boettcher, S.3
Lebrun, V.4
Gemperlein, K.5
Lederer, E.6
Leclercq, I.A.7
Mueller, R.8
Hartmann, R.W.9
Haybaeck, J.10
Kiemer, A.K.11
-
6
-
-
84881454013
-
Proteomic and lipidomic signatures of lipid metabolism in NASH-associated hepatocellular carcinoma
-
PMID: 23749645
-
Muir K, Hazim A, He Y, Peyressatre M, Kim DY, Song X, Beretta L. Proteomic and lipidomic signatures of lipid metabolism in NASH-associated hepatocellular carcinoma. Cancer Res 2013; 73: 4722-4731 [PMID: 23749645 DOI: 10.1158/0008-5472.CAN-12-3797]
-
(2013)
Cancer Res
, vol.73
, pp. 4722-4731
-
-
Muir, K.1
Hazim, A.2
He, Y.3
Peyressatre, M.4
Kim, D.Y.5
Song, X.6
Beretta, L.7
-
7
-
-
84898766063
-
Lipid metabolism signatures in NASH-associated HCC. - Letter
-
PMID: 24778416
-
Kessler SM, Laggai S, Barghash A, Helms V, Kiemer AK. Lipid metabolism signatures in NASH-associated HCC. - letter. Cancer Res 2014; 74: 2903-2904 [PMID: 24778416 DOI: 10.1158/0008-5472.CAN-13-2852.]
-
(2014)
Cancer Res
, vol.74
, pp. 2903-2904
-
-
Kessler, S.M.1
Laggai, S.2
Barghash, A.3
Helms, V.4
Kiemer, A.K.5
-
8
-
-
39849103404
-
Hepatic free fatty acids accumulate in experimental steatohepatitis: Role of adaptive pathways
-
PMID: 18280001
-
Larter CZ, Yeh MM, Haigh WG, Williams J, Brown S, Bell-Anderson KS, Lee SP, Farrell GC. Hepatic free fatty acids accumulate in experimental steatohepatitis: role of adaptive pathways. J Hepatol 2008; 48: 638-647 [PMID: 18280001 DOI: 10.1016/j.jhep.2007.12.011]
-
(2008)
J Hepatol
, vol.48
, pp. 638-647
-
-
Larter, C.Z.1
Yeh, M.M.2
Haigh, W.G.3
Williams, J.4
Brown, S.5
Bell-Anderson, K.S.6
Lee, S.P.7
Farrell, G.C.8
-
9
-
-
84863524881
-
Liver cholesterol: Is it playing possum in NASH?
-
PMID: 22556144
-
Farrell GC, van Rooyen D. Liver cholesterol: is it playing possum in NASH? Am J Physiol Gastrointest Liver Physiol 2012; 303: G9-11 [PMID: 22556144 DOI: 10.1152/ajpgi.00008.2012]
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.303
, pp. G9-G11
-
-
Farrell, G.C.1
Van Rooyen, D.2
-
10
-
-
84876803994
-
Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis
-
PMID: 23417738
-
Ioannou GN, Haigh WG, Thorning D, Savard C. Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis. J Lipid Res 2013; 54: 1326-1334 [PMID: 23417738 DOI: 10.1194/jlr.M034876]
-
(2013)
J Lipid Res
, vol.54
, pp. 1326-1334
-
-
Ioannou, G.N.1
Haigh, W.G.2
Thorning, D.3
Savard, C.4
-
11
-
-
73149094543
-
The plasma lipidomic signature of nonalcoholic steatohepatitis
-
PMID: 19937697
-
Puri P, Wiest MM, Cheung O, Mirshahi F, Sargeant C, Min HK, Contos MJ, Sterling RK, Fuchs M, Zhou H, Watkins SM, Sanyal AJ. The plasma lipidomic signature of nonalcoholic steatohepatitis. Hepatology 2009; 50: 1827-1838 [PMID: 19937697 DOI: 10.1158/0008-5472]
-
(2009)
Hepatology
, vol.50
, pp. 1827-1838
-
-
Puri, P.1
Wiest, M.M.2
Cheung, O.3
Mirshahi, F.4
Sargeant, C.5
Min, H.K.6
Contos, M.J.7
Sterling, R.K.8
Fuchs, M.9
Zhou, H.10
Watkins, S.M.11
Sanyal, A.J.12
-
12
-
-
84894875873
-
Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice
-
PMID: 23832448
-
Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Okada Y, Kurihara C, Irie R, Yokoyama H, Shimamura K, Usui S, Ebinuma H, Saito H, Watanabe C, Komoto S, Kawaguchi A, Nagao S, Sugiyama K, Hokari R, Kanai T, Miura S, Hibi T. Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice. Hepatology 2014; 59: 154-169 [PMID: 23832448 DOI: 10.1002/hep.26604]
-
(2014)
Hepatology
, vol.59
, pp. 154-169
-
-
Tomita, K.1
Teratani, T.2
Suzuki, T.3
Shimizu, M.4
Sato, H.5
Narimatsu, K.6
Okada, Y.7
Kurihara, C.8
Irie, R.9
Yokoyama, H.10
Shimamura, K.11
Usui, S.12
Ebinuma, H.13
Saito, H.14
Watanabe, C.15
Komoto, S.16
Kawaguchi, A.17
Nagao, S.18
Sugiyama, K.19
Hokari, R.20
Kanai, T.21
Miura, S.22
Hibi, T.23
more..
-
13
-
-
49649110937
-
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
-
PMID: 18666236
-
Wouters K, van Gorp PJ, Bieghs V, Gijbels MJ, Duimel H, Lütjohann D, Kerksiek A, van Kruchten R, Maeda N, Staels B, van Bilsen M, Shiri-Sverdlov R, Hofker MH. Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology 2008; 48: 474-486 [PMID: 18666236 DOI: 10.1002/hep.22363]
-
(2008)
Hepatology
, vol.48
, pp. 474-486
-
-
Wouters, K.1
Van Gorp, P.J.2
Bieghs, V.3
Gijbels, M.J.4
Duimel, H.5
Lütjohann, D.6
Kerksiek, A.7
Van Kruchten, R.8
Maeda, N.9
Staels, B.10
Van Bilsen, M.11
Shiri-Sverdlov, R.12
Hofker, M.H.13
-
14
-
-
0033526101
-
A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma
-
PMID: 10190901
-
Zhang JY, Chan EK, Peng XX, Tan EM. A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma. J Exp Med 1999; 189: 1101-1110 [PMID: 10190901 DOI: 10.1084/jem.189.7.1101]
-
(1999)
J Exp Med
, vol.189
, pp. 1101-1110
-
-
Zhang, J.Y.1
Chan, E.K.2
Peng, X.X.3
Tan, E.M.4
-
15
-
-
0034856833
-
Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis
-
PMID: 11549587
-
Lu M, Nakamura RM, Dent ED, Zhang JY, Nielsen FC, Christiansen J, Chan EK, Tan EM. Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis. Am J Pathol 2001; 159: 945-953 [PMID: 11549587 DOI: 10.1016/ S0002-9440(10)61770-1]
-
(2001)
Am J Pathol
, vol.159
, pp. 945-953
-
-
Lu, M.1
Nakamura, R.M.2
Dent, E.D.3
Zhang, J.Y.4
Nielsen, F.C.5
Christiansen, J.6
Chan, E.K.7
Tan, E.M.8
-
16
-
-
84874095808
-
IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: Antiapoptotic action is independent of IGF2/PI3K signaling
-
PMID: 23257922
-
Kessler SM, Pokorny J, Zimmer V, Laggai S, Lammert F, Bohle RM, Kiemer AK. IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling. Am J Physiol Gastrointest Liver Physiol 2013; 304: G328-G336 [PMID: 23257922 DOI: 10.1152/ajpgi.00005.2012]
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.304
, pp. G328-G336
-
-
Kessler, S.M.1
Pokorny, J.2
Zimmer, V.3
Laggai, S.4
Lammert, F.5
Bohle, R.M.6
Kiemer, A.K.7
-
17
-
-
84880313066
-
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): Post-transcriptional drivers of cancer progression?
-
PMID: 23069990
-
Bell JL, Wächter K, Mühleck B, Pazaitis N, Köhn M, Lederer M, Hüttelmaier S. Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression? Cell Mol Life Sci 2013; 70 : 2657-2675 [PMID: 23069990 DOI: 10.1007/s00018-012-1186-z]
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 2657-2675
-
-
Bell, J.L.1
Wächter, K.2
Mühleck, B.3
Pazaitis, N.4
Köhn, M.5
Lederer, M.6
Hüttelmaier, S.7
-
18
-
-
84897969932
-
The insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IGF2BP2-2 as a promoter of NAFLD and HCC?
-
PMID: 24173291
-
Simon Y, Kessler SM, Bohle RM, Haybaeck J, Kiemer AK. The insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IGF2BP2-2 as a promoter of NAFLD and HCC? Gut 2014; 63: 861-863 [PMID: 24173291 DOI: 10.1136/gutjnl-2013-305736]
-
(2014)
Gut
, vol.63
, pp. 861-863
-
-
Simon, Y.1
Kessler, S.M.2
Bohle, R.M.3
Haybaeck, J.4
Kiemer, A.K.5
-
19
-
-
79954648698
-
Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype
-
PMID: 21145819
-
Tybl E, Shi FD, Kessler SM, Tierling S, Walter J, Bohle RM, Wieland S, Zhang J, Tan EM, Kiemer AK. Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype. J Hepatol 2011; 54: 994-1001 [PMID: 21145819 DOI: 10.1016/j.jhep.2010.08.034]
-
(2011)
J Hepatol
, vol.54
, pp. 994-1001
-
-
Tybl, E.1
Shi, F.D.2
Kessler, S.M.3
Tierling, S.4
Walter, J.5
Bohle, R.M.6
Wieland, S.7
Zhang, J.8
Tan, E.M.9
Kiemer, A.K.10
-
20
-
-
84874600567
-
Animal models of chronic liver diseases
-
PMID: 23275613
-
Liu Y, Meyer C, Xu C, Weng H, Hellerbrand C, ten Dijke P, Dooley S. Animal models of chronic liver diseases. Am J Physiol Gastrointest Liver Physiol 2013; 304: G449-G468 [PMID: 23275613 DOI: 10.1152/ajpgi.00199.2012]
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.304
, pp. G449-G468
-
-
Liu, Y.1
Meyer, C.2
Xu, C.3
Weng, H.4
Hellerbrand, C.5
Ten Dijke, P.6
Dooley, S.7
-
21
-
-
84856954278
-
Iron and steatohepatitis
-
PMID: 22320915
-
Corradini E, Pietrangelo A. Iron and steatohepatitis. J Gastroenterol Hepatol 2012; 27 Suppl 2: 42-46 [PMID: 22320915 DOI: 10.1111/j.1440-1746.2011.07014.x]
-
(2012)
J Gastroenterol Hepatol
, vol.27
, pp. 42-46
-
-
Corradini, E.1
Pietrangelo, A.2
-
22
-
-
63449095969
-
Effects of lactational exposure to benzo[alpha]pyrene (B[alpha]P) on postnatal neurodevelopment, neuronal receptor gene expression and behaviour in mice
-
PMID: 19428949
-
Bouayed J, Desor F, Rammal H, Kiemer AK, Tybl E, Schroeder H, Rychen G, Soulimani R. Effects of lactational exposure to benzo[alpha]pyrene (B[alpha]P) on postnatal neurodevelopment, neuronal receptor gene expression and behaviour in mice. Toxicology 2009; 259: 97-106 [PMID: 19428949 DOI: 10.1016/j.tox.2009.02.010]
-
(2009)
Toxicology
, vol.259
, pp. 97-106
-
-
Bouayed, J.1
Desor, F.2
Rammal, H.3
Kiemer, A.K.4
Tybl, E.5
Schroeder, H.6
Rychen, G.7
Soulimani, R.8
-
23
-
-
79955376789
-
Fatty acid-related phylogeny of myxobacteria as an approach to discover polyunsaturated omega-3/6 Fatty acids
-
PMID: 21317327
-
Garcia R, Pistorius D, Stadler M, Müller R. Fatty acid-related phylogeny of myxobacteria as an approach to discover polyunsaturated omega-3/6 Fatty acids. J Bacteriol 2011; 193: 1930-1942 [PMID: 21317327 DOI: 10.1128/JB.01091-10]
-
(2011)
J Bacteriol
, vol.193
, pp. 1930-1942
-
-
Garcia, R.1
Pistorius, D.2
Stadler, M.3
Müller, R.4
-
24
-
-
0036830306
-
In vivo regulation of inducible no synthase in immune-mediated liver injury in mice
-
PMID: 12395315
-
Koerber K, Sass G, Kiemer AK, Vollmar AM, Tiegs G. In vivo regulation of inducible no synthase in immune-mediated liver injury in mice. Hepatology 2002; 36: 1061-1069 [PMID: 12395315 DOI: 10.1053/jhep.2002.36155]
-
(2002)
Hepatology
, vol.36
, pp. 1061-1069
-
-
Koerber, K.1
Sass, G.2
Kiemer, A.K.3
Vollmar, A.M.4
Tiegs, G.5
-
25
-
-
0023833533
-
The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes
-
PMID: 3343237
-
Yao ZM, Vance DE. The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes. J Biol Chem 1988; 263: 2998-3004 [PMID: 3343237]
-
(1988)
J Biol Chem
, vol.263
, pp. 2998-3004
-
-
Yao, Z.M.1
Vance, D.E.2
-
26
-
-
39149112455
-
Interstrain differences in susceptibility to non-alcoholic steatohepatitis
-
PMID: 17868334
-
Yamazaki Y, Kakizaki S, Takizawa D, Ichikawa T, Sato K, Takagi H, Mori M. Interstrain differences in susceptibility to non-alcoholic steatohepatitis. J Gastroenterol Hepatol 2008; 23: 276-282 [PMID: 17868334 DOI: 10.1111/j.1440-1746.2007.05150.x]
-
(2008)
J Gastroenterol Hepatol
, vol.23
, pp. 276-282
-
-
Yamazaki, Y.1
Kakizaki, S.2
Takizawa, D.3
Ichikawa, T.4
Sato, K.5
Takagi, H.6
Mori, M.7
-
27
-
-
77955668811
-
Hepatic iron loading in mice increases cholesterol biosynthesis
-
PMID: 20683946
-
Graham RM, Chua AC, Carter KW, Delima RD, Johnstone D, Herbison CE, Firth MJ, O'Leary R, Milward EA, Olynyk JK, Trinder D. Hepatic iron loading in mice increases cholesterol biosynthesis. Hepatology 2010; 52: 462-471 [PMID: 20683946 DOI: 10.1002/hep.23712]
-
(2010)
Hepatology
, vol.52
, pp. 462-471
-
-
Graham, R.M.1
Chua, A.C.2
Carter, K.W.3
Delima, R.D.4
Johnstone, D.5
Herbison, C.E.6
Firth, M.J.7
O'Leary, R.8
Milward, E.A.9
Olynyk, J.K.10
Trinder, D.11
-
28
-
-
61849095626
-
Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH
-
PMID: 19231010
-
Caballero F, Fernández A, De Lacy AM, Fernández-Checa JC, Caballería J, García-Ruiz C. Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH. J Hepatol 2009; 50 : 789-796 [PMID: 19231010 DOI: 10.1016/j.jhep.2008.12.016]
-
(2009)
J Hepatol
, vol.50
, pp. 789-796
-
-
Caballero, F.1
Fernández, A.2
De Lacy, A.M.3
Fernández-Checa, J.C.4
Caballería, J.5
García-Ruiz, C.6
-
29
-
-
84860469242
-
Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease
-
PMID: 22560219
-
Min HK, Kapoor A, Fuchs M, Mirshahi F, Zhou H, Maher J, Kellum J, Warnick R, Contos MJ, Sanyal AJ. Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease. Cell Metab 2012; 15: 665-674 [PMID: 22560219 DOI: 10.1016/j.cmet.2012.04.004]
-
(2012)
Cell Metab
, vol.15
, pp. 665-674
-
-
Min, H.K.1
Kapoor, A.2
Fuchs, M.3
Mirshahi, F.4
Zhou, H.5
Maher, J.6
Kellum, J.7
Warnick, R.8
Contos, M.J.9
Sanyal, A.J.10
-
30
-
-
84875625146
-
Nonalcoholic fatty liver disease as an independent manifestation of the metabolic syndrome: Results of a US national survey in three ethnic groups
-
PMID: 23286209
-
Smits MM, Ioannou GN, Boyko EJ, Utzschneider KM. Nonalcoholic fatty liver disease as an independent manifestation of the metabolic syndrome: results of a US national survey in three ethnic groups. J Gastroenterol Hepatol 2013; 28: 664-670 [PMID: 23286209 DOI: 10.1111/jgh.12106]
-
(2013)
J Gastroenterol Hepatol
, vol.28
, pp. 664-670
-
-
Smits, M.M.1
Ioannou, G.N.2
Boyko, E.J.3
Utzschneider, K.M.4
-
31
-
-
20444374054
-
Downregulated expression of PPARalpha target genes, reduced fatty acid oxidation and altered fatty acid composition in the liver of mice transgenic for hTNFalpha
-
PMID: 15893958 10.1016/j.bbalip.2005.02.011
-
Glosli H, Gudbrandsen OA, Mullen AJ, Halvorsen B, Rost TH, Wergedahl H, Prydz H, Aukrust P, Berge RK. Downregulated expression of PPARalpha target genes, reduced fatty acid oxidation and altered fatty acid composition in the liver of mice transgenic for hTNFalpha. Biochim Biophys Acta 2005; 1734 : 235-246 [PMID: 15893958 DOI: 10.1016/j.bbalip.2005.02.011]
-
(2005)
Biochim Biophys Acta
, vol.1734
, pp. 235-246
-
-
Glosli, H.1
Gudbrandsen, O.A.2
Mullen, A.J.3
Halvorsen, B.4
Rost, T.H.5
Wergedahl, H.6
Prydz, H.7
Aukrust, P.8
Berge, R.K.9
-
32
-
-
33646014467
-
Serum cytokine and soluble cytokine receptor levels in patients with non-alcoholic steatohepatitis
-
PMID: 16420507
-
Abiru S, Migita K, Maeda Y, Daikoku M, Ito M, Ohata K, Nagaoka S, Matsumoto T, Takii Y, Kusumoto K, Nakamura M, Komori A, Yano K, Yatsuhashi H, Eguchi K, Ishibashi H. Serum cytokine and soluble cytokine receptor levels in patients with non-alcoholic steatohepatitis. Liver Int 2006; 26: 39-45 [PMID: 16420507 DOI: 10.1111/j.1478-3231.2005.01191.x]
-
(2006)
Liver Int
, vol.26
, pp. 39-45
-
-
Abiru, S.1
Migita, K.2
Maeda, Y.3
Daikoku, M.4
Ito, M.5
Ohata, K.6
Nagaoka, S.7
Matsumoto, T.8
Takii, Y.9
Kusumoto, K.10
Nakamura, M.11
Komori, A.12
Yano, K.13
Yatsuhashi, H.14
Eguchi, K.15
Ishibashi, H.16
-
33
-
-
0042165989
-
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
-
PMID: 12891546
-
Feldstein AE, Canbay A, Angulo P, Taniai M, Burgart LJ, Lindor KD, Gores GJ. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology 2003; 125: 437-443 [PMID: 12891546 DOI: 10.1016/S0016-5085(03)00907-7]
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
Taniai, M.4
Burgart, L.J.5
Lindor, K.D.6
Gores, G.J.7
-
34
-
-
21044437187
-
Immune response towards lipid peroxidation products as a predictor of progression of non-alcoholic fatty liver disease to advanced fibrosis
-
PMID: 15951547
-
Albano E, Mottaran E, Vidali M, Reale E, Saksena S, Occhino G, Burt AD, Day CP. Immune response towards lipid peroxidation products as a predictor of progression of non-alcoholic fatty liver disease to advanced fibrosis. Gut 2005; 54: 987-993 [PMID: 15951547 DOI: 10.1136/gut.2004.057968]
-
(2005)
Gut
, vol.54
, pp. 987-993
-
-
Albano, E.1
Mottaran, E.2
Vidali, M.3
Reale, E.4
Saksena, S.5
Occhino, G.6
Burt, A.D.7
Day, C.P.8
-
35
-
-
33645963118
-
COX-2 induction in mice with experimental nutritional steatohepatitis: Role as proinflammatory mediator
-
PMID: 16557554
-
Yu J, Ip E, Dela Peña A, Hou JY, Sesha J, Pera N, Hall P, Kirsch R, Leclercq I, Farrell GC. COX-2 induction in mice with experimental nutritional steatohepatitis: Role as proinflammatory mediator. Hepatology 2006; 43: 826-836 [PMID: 16557554 DOI: 10.1002/hep.21108]
-
(2006)
Hepatology
, vol.43
, pp. 826-836
-
-
Yu, J.1
Ip, E.2
Dela Peña, A.3
Hou, J.Y.4
Sesha, J.5
Pera, N.6
Hall, P.7
Kirsch, R.8
Leclercq, I.9
Farrell, G.C.10
-
36
-
-
75449101395
-
Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity
-
PMID: 20054868
-
Stienstra R, Saudale F, Duval C, Keshtkar S, Groener JE, van Rooijen N, Staels B, Kersten S, Müller M. Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity. Hepatology 2010; 51: 511-522 [PMID: 20054868 DOI: 10.1002/hep.23337]
-
(2010)
Hepatology
, vol.51
, pp. 511-522
-
-
Stienstra, R.1
Saudale, F.2
Duval, C.3
Keshtkar, S.4
Groener, J.E.5
Van Rooijen, N.6
Staels, B.7
Kersten, S.8
Müller, M.9
-
37
-
-
46049108007
-
Plasma palmitoleic acid, a product of stearoyl-coA desaturase activity, is an independent marker of triglyceridemia and abdominal adiposity
-
PMID: 18068341
-
Paillard F, Catheline D, Duff FL, Bouriel M, Deugnier Y, Pouchard M, Daubert JC, Legrand P. Plasma palmitoleic acid, a product of stearoyl-coA desaturase activity, is an independent marker of triglyceridemia and abdominal adiposity. Nutr Metab Cardiovasc Dis 2008; 18: 436-440 [PMID: 18068341 DOI: 10.1016/j.numecd.2007.02.017]
-
(2008)
Nutr Metab Cardiovasc Dis
, vol.18
, pp. 436-440
-
-
Paillard, F.1
Catheline, D.2
Duff, F.L.3
Bouriel, M.4
Deugnier, Y.5
Pouchard, M.6
Daubert, J.C.7
Legrand, P.8
-
38
-
-
33645506335
-
Identification of mouse palmitoyl-coenzyme A Delta9-desaturase
-
PMID: 16443825
-
Miyazaki M, Bruggink SM, Ntambi JM. Identification of mouse palmitoyl-coenzyme A Delta9-desaturase. J Lipid Res 2006; 47: 700-704 [PMID: 16443825 DOI: 10.1194/jlr.C500025-JLR200]
-
(2006)
J Lipid Res
, vol.47
, pp. 700-704
-
-
Miyazaki, M.1
Bruggink, S.M.2
Ntambi, J.M.3
-
39
-
-
0345276007
-
Regulation of stearoyl-CoA desaturases and role in metabolism
-
PMID: 14654089
-
Ntambi JM, Miyazaki M. Regulation of stearoyl-CoA desaturases and role in metabolism. Prog Lipid Res 2004; 43: 91-104 [PMID: 14654089 DOI: 10.1016/S0163-7827(03)00039-0]
-
(2004)
Prog Lipid Res
, vol.43
, pp. 91-104
-
-
Ntambi, J.M.1
Miyazaki, M.2
-
40
-
-
84870541988
-
Elovl6 promotes nonalcoholic steatohepatitis
-
PMID: 22753171
-
Matsuzaka T, Atsumi A, Matsumori R, Nie T, Shinozaki H, Suzuki-Kemuriyama N, Kuba M, Nakagawa Y, Ishii K, Shimada M, Kobayashi K, Yatoh S, Takahashi A, Takekoshi K, Sone H, Yahagi N, Suzuki H, Murata S, Nakamuta M, Yamada N, Shimano H. Elovl6 promotes nonalcoholic steatohepatitis. Hepatology 2012; 56: 2199-2208 [PMID: 22753171 DOI: 10.1002/hep.25932]
-
(2012)
Hepatology
, vol.56
, pp. 2199-2208
-
-
Matsuzaka, T.1
Atsumi, A.2
Matsumori, R.3
Nie, T.4
Shinozaki, H.5
Suzuki-Kemuriyama, N.6
Kuba, M.7
Nakagawa, Y.8
Ishii, K.9
Shimada, M.10
Kobayashi, K.11
Yatoh, S.12
Takahashi, A.13
Takekoshi, K.14
Sone, H.15
Yahagi, N.16
Suzuki, H.17
Murata, S.18
Nakamuta, M.19
Yamada, N.20
Shimano, H.21
more..
-
41
-
-
33644955272
-
Mouse models in non-alcoholic fatty liver disease and steatohepatitis research
-
PMID: 16436109
-
Anstee QM, Goldin RD. Mouse models in non-alcoholic fatty liver disease and steatohepatitis research. Int J Exp Pathol 2006; 87: 1-16 [PMID: 16436109 DOI: 10.1111/j.0959-9673.2006.00465.x]
-
(2006)
Int J Exp Pathol
, vol.87
, pp. 1-16
-
-
Anstee, Q.M.1
Goldin, R.D.2
-
42
-
-
84872493396
-
Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis
-
PMID: 23206728
-
Musso G, Gambino R, Cassader M. Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis. Prog Lipid Res 2013; 52: 175-191 [PMID: 23206728 DOI: 10.1016/ j.plipres.2012.11.002]
-
(2013)
Prog Lipid Res
, vol.52
, pp. 175-191
-
-
Musso, G.1
Gambino, R.2
Cassader, M.3
-
43
-
-
84860326669
-
NASH is an inflammatory disorder: Pathogenic, prognostic and therapeutic implications
-
PMID: 22570745
-
Farrell GC, van Rooyen D, Gan L, Chitturi S. NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications. Gut Liver 2012; 6: 149-171 [PMID: 22570745 DOI: 10.5009/gnl.2012.6.2.149]
-
(2012)
Gut Liver
, vol.6
, pp. 149-171
-
-
Farrell, G.C.1
Van Rooyen, D.2
Gan, L.3
Chitturi, S.4
-
44
-
-
60549103890
-
Iron overload is associated with hepatic oxidative damage to DNA in nonalcoholic steatohepatitis
-
PMID: 19190144
-
Fujita N, Miyachi H, Tanaka H, Takeo M, Nakagawa N, Kobayashi Y, Iwasa M, Watanabe S, Takei Y. Iron overload is associated with hepatic oxidative damage to DNA in nonalcoholic steatohepatitis. Cancer Epidemiol Biomarkers Prev 2009; 18: 424-432 [PMID: 19190144 DOI: 10.1158/1055-9965.EPI-08-0725]
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 424-432
-
-
Fujita, N.1
Miyachi, H.2
Tanaka, H.3
Takeo, M.4
Nakagawa, N.5
Kobayashi, Y.6
Iwasa, M.7
Watanabe, S.8
Takei, Y.9
-
45
-
-
58149280387
-
Liver iron excess in patients with hepatocellular carcinoma developed on non-alcoholic steato-hepatitis
-
PMID: 19070395
-
Sorrentino P, D'Angelo S, Ferbo U, Micheli P, Bracigliano A, Vecchione R. Liver iron excess in patients with hepatocellular carcinoma developed on non-alcoholic steato-hepatitis. J Hepatol 2009; 50: 351-357 [PMID: 19070395 DOI: 10.1016/j.jhep.2008.09.011]
-
(2009)
J Hepatol
, vol.50
, pp. 351-357
-
-
Sorrentino, P.1
D'Angelo, S.2
Ferbo, U.3
Micheli, P.4
Bracigliano, A.5
Vecchione, R.6
-
46
-
-
84867733827
-
Interactions between hepatic iron and lipid metabolism with possible relevance to steatohepatitis
-
PMID: 23002334
-
Ahmed U, Latham PS, Oates PS. Interactions between hepatic iron and lipid metabolism with possible relevance to steatohepatitis. World J Gastroenterol 2012; 18 : 4651-4658 [PMID: 23002334 DOI: 10.3748/wjg.v18.i34.4651]
-
(2012)
World J Gastroenterol
, vol.18
, pp. 4651-4658
-
-
Ahmed, U.1
Latham, P.S.2
Oates, P.S.3
-
47
-
-
0035953016
-
Stearoyl coenzyme A desaturase 1 expression and activity are increased in the liver during iron overload
-
PMID: 11278167
-
Pigeon C, Legrand P, Leroyer P, Bouriel M, Turlin B, Brissot P, Loréal O. Stearoyl coenzyme A desaturase 1 expression and activity are increased in the liver during iron overload. Biochim Biophys Acta 2001; 1535: 275-284 [PMID: 11278167 DOI: 10.1016/S0925-4439(01)00024-2]
-
(2001)
Biochim Biophys Acta
, vol.1535
, pp. 275-284
-
-
Pigeon, C.1
Legrand, P.2
Leroyer, P.3
Bouriel, M.4
Turlin, B.5
Brissot, P.6
Loréal, O.7
-
48
-
-
34648830569
-
Role of iron in hepatic fibrosis: One piece in the puzzle
-
PMID: 17729396
-
Philippe MA, Ruddell RG, Ramm GA. Role of iron in hepatic fibrosis: one piece in the puzzle. World J Gastroenterol 2007; 13: 4746-4754 [PMID: 17729396]
-
(2007)
World J Gastroenterol
, vol.13
, pp. 4746-4754
-
-
Philippe, M.A.1
Ruddell, R.G.2
Ramm, G.A.3
-
49
-
-
0035991444
-
In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases
-
PMID: 12076862
-
Seki S, Kitada T, Yamada T, Sakaguchi H, Nakatani K, Wakasa K. In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases. J Hepatol 2002; 37: 56-62 [PMID: 12076862 DOI: 10.1016/S0168-8278(02)00073-9]
-
(2002)
J Hepatol
, vol.37
, pp. 56-62
-
-
Seki, S.1
Kitada, T.2
Yamada, T.3
Sakaguchi, H.4
Nakatani, K.5
Wakasa, K.6
|