메뉴 건너뛰기




Volumn 10, Issue 12, 2014, Pages

Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

EID: 84919683994     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004824     Document Type: Article
Times cited : (64)

References (98)
  • 1
    • 33846466508 scopus 로고    scopus 로고
    • Epidemiology of invasive candidiasis: a persistent public health proble
    • Pfaller MA, Diekema DJ, (2007) Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev 20: 133–163.
    • (2007) Clin Microbiol Rev , vol.20 , pp. 133-163
    • Pfaller, M.A.1    Diekema, D.J.2
  • 2
    • 27244436568 scopus 로고    scopus 로고
    • Contributions of hyphae and hypha-co-regulated genes to Candida albicans virulenc
    • Kumamoto CA, Vinces MD, (2005) Contributions of hyphae and hypha-co-regulated genes to Candida albicans virulence. Cell Microbiol 7: 1546–1554.
    • (2005) Cell Microbiol , vol.7 , pp. 1546-1554
    • Kumamoto, C.A.1    Vinces, M.D.2
  • 4
    • 0030732768 scopus 로고    scopus 로고
    • Misexpression of the white-phase-specific gene WH11 in the opaque phase of Candida albicans affects switching and virulenc
    • Kvaal CA, Srikantha T, Soll DR, (1997) Misexpression of the white-phase-specific gene WH11 in the opaque phase of Candida albicans affects switching and virulence. Infect Immun 65: 4468–4475.
    • (1997) Infect Immun , vol.65 , pp. 4468-4475
    • Kvaal, C.A.1    Srikantha, T.2    Soll, D.R.3
  • 5
    • 84874217979 scopus 로고    scopus 로고
    • Candida albicans pathogenicity mechanism
    • Mayer FL, Wilson D, Hube B, (2013) Candida albicans pathogenicity mechanisms. Virulence 4: 119–128.
    • (2013) Virulence , vol.4 , pp. 119-128
    • Mayer, F.L.1    Wilson, D.2    Hube, B.3
  • 7
    • 0033405366 scopus 로고    scopus 로고
    • Increased susceptibility to systemic candidiasis in interleukin-6 deficient mic
    • van Enckevort FH, Netea MG, Hermus AR, Sweep CG, Meis JF, et al. (1999) Increased susceptibility to systemic candidiasis in interleukin-6 deficient mice. Med Mycol 37: 419–426.
    • (1999) Med Mycol , vol.37 , pp. 419-426
    • van Enckevort, F.H.1    Netea, M.G.2    Hermus, A.R.3    Sweep, C.G.4    Meis, J.F.5
  • 8
    • 0030914272 scopus 로고    scopus 로고
    • Stable azole drug resistance associated with a substrain of Candida albicans from an HIV-infected patien
    • White TC, Pfaller MA, Rinaldi MG, Smith J, Redding SW, (1997) Stable azole drug resistance associated with a substrain of Candida albicans from an HIV-infected patient. Oral Dis 3 Suppl 1: S102–109.
    • (1997) Oral Dis , vol.3 Suppl 1 , pp. S102-109
    • White, T.C.1    Pfaller, M.A.2    Rinaldi, M.G.3    Smith, J.4    Redding, S.W.5
  • 9
    • 0025210157 scopus 로고
    • Chromosomal rearrangements associated with morphological mutants provide a means for genetic variation of Candida albican
    • Rustchenko-Bulgac EP, Sherman F, Hicks JB, (1990) Chromosomal rearrangements associated with morphological mutants provide a means for genetic variation of Candida albicans. J Bacteriol 172: 1276–1283.
    • (1990) J Bacteriol , vol.172 , pp. 1276-1283
    • Rustchenko-Bulgac, E.P.1    Sherman, F.2    Hicks, J.B.3
  • 10
    • 4644312650 scopus 로고    scopus 로고
    • Microevolution of Candida albicans strains during catheter-related candidemi
    • Shin JH, Park MR, Song JW, Shin DH, Jung SI, et al. (2004) Microevolution of Candida albicans strains during catheter-related candidemia. J Clin Microbiol 42: 4025–4031.
    • (2004) J Clin Microbiol , vol.42 , pp. 4025-4031
    • Shin, J.H.1    Park, M.R.2    Song, J.W.3    Shin, D.H.4    Jung, S.I.5
  • 11
    • 33749173831 scopus 로고    scopus 로고
    • Evolution of alternative transcriptional circuits with identical logi
    • Tsong AE, Tuch BB, Li H, Johnson AD, (2006) Evolution of alternative transcriptional circuits with identical logic. Nature 443: 415–420.
    • (2006) Nature , vol.443 , pp. 415-420
    • Tsong, A.E.1    Tuch, B.B.2    Li, H.3    Johnson, A.D.4
  • 13
    • 70349321199 scopus 로고    scopus 로고
    • Evolution in Candida albicans populations during a single passage through a mouse hos
    • Forche A, Magee PT, Selmecki A, Berman J, May G, (2009) Evolution in Candida albicans populations during a single passage through a mouse host. Genetics 182: 799–811.
    • (2009) Genetics , vol.182 , pp. 799-811
    • Forche, A.1    Magee, P.T.2    Selmecki, A.3    Berman, J.4    May, G.5
  • 14
    • 80052965456 scopus 로고    scopus 로고
    • Growth of Candida albicans hypha
    • Sudbery PE, (2011) Growth of Candida albicans hyphae. Nat Rev Microbiol 9: 737–748.
    • (2011) Nat Rev Microbiol , vol.9 , pp. 737-748
    • Sudbery, P.E.1
  • 16
    • 33846027505 scopus 로고    scopus 로고
    • Fungal invasion of normally non-phagocytic host cell
    • Filler SG, Sheppard DC, (2006) Fungal invasion of normally non-phagocytic host cells. PLoS Pathog 2: e129.
    • (2006) PLoS Pathog , vol.2 , pp. 129
    • Filler, S.G.1    Sheppard, D.C.2
  • 17
    • 79952019135 scopus 로고    scopus 로고
    • From attachment to damage: defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cell
    • Wächtler B, Wilson D, Haedicke K, Dalle F, Hube B, (2011) From attachment to damage: defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cells. PLoS One 6: e17046.
    • (2011) PLoS One , vol.6 , pp. 17046
    • Wächtler, B.1    Wilson, D.2    Haedicke, K.3    Dalle, F.4    Hube, B.5
  • 18
    • 84893354236 scopus 로고    scopus 로고
    • Candida albicans triggers NLRP3-mediated pyroptosis in macrophage
    • Wellington M, Koselny K, Sutterwala FS, Krysan DJ, (2014) Candida albicans triggers NLRP3-mediated pyroptosis in macrophages. Eukaryot Cell 13: 329–340.
    • (2014) Eukaryot Cell , vol.13 , pp. 329-340
    • Wellington, M.1    Koselny, K.2    Sutterwala, F.S.3    Krysan, D.J.4
  • 19
    • 84899731243 scopus 로고    scopus 로고
    • The pathogen Candida albicans hijacks pyroptosis for escape from macrophage
    • Uwamahoro N, Verma-Gaur J, Shen HH, Qu Y, Lewis R, et al. (2014) The pathogen Candida albicans hijacks pyroptosis for escape from macrophages. MBio 5: e00003–00014.
    • (2014) MBio , vol.5 , pp. 00003-00014
    • Uwamahoro, N.1    Verma-Gaur, J.2    Shen, H.H.3    Qu, Y.4    Lewis, R.5
  • 20
    • 6344285788 scopus 로고    scopus 로고
    • Transcriptional response of Candida albicans upon internalization by macrophage
    • Lorenz MC, Bender JA, Fink GR, (2004) Transcriptional response of Candida albicans upon internalization by macrophages. Eukaryot Cell 3: 1076–1087.
    • (2004) Eukaryot Cell , vol.3 , pp. 1076-1087
    • Lorenz, M.C.1    Bender, J.A.2    Fink, G.R.3
  • 21
    • 84855872990 scopus 로고    scopus 로고
    • Candida albicans morphogenesis and host defence: discriminating invasion from colonizatio
    • Gow NA, van de Veerdonk FL, Brown AJ, Netea MG, (2011) Candida albicans morphogenesis and host defence: discriminating invasion from colonization. Nat Rev Microbiol 10: 112–122.
    • (2011) Nat Rev Microbiol , vol.10 , pp. 112-122
    • Gow, N.A.1    van de Veerdonk, F.L.2    Brown, A.J.3    Netea, M.G.4
  • 23
    • 0030945488 scopus 로고    scopus 로고
    • Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fung
    • Stoldt VR, Sonneborn A, Leuker CE, Ernst JF, (1997) Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi. Embo J 16: 1982–1991.
    • (1997) Embo J , vol.16 , pp. 1982-1991
    • Stoldt, V.R.1    Sonneborn, A.2    Leuker, C.E.3    Ernst, J.F.4
  • 25
    • 2942662225 scopus 로고    scopus 로고
    • Lipid raft polarization contributes to hyphal growth in Candida albican
    • Martin SW, Konopka JB, (2004) Lipid raft polarization contributes to hyphal growth in Candida albicans. Eukaryot Cell 3: 675–684.
    • (2004) Eukaryot Cell , vol.3 , pp. 675-684
    • Martin, S.W.1    Konopka, J.B.2
  • 26
    • 0024443395 scopus 로고
    • A morphology index for characterization of cell shape in Candida albican
    • Merson-Davies LA, Odds FC, (1989) A morphology index for characterization of cell shape in Candida albicans. J Gen Microbiol 135: 3143–3152.
    • (1989) J Gen Microbiol , vol.135 , pp. 3143-3152
    • Merson-Davies, L.A.1    Odds, F.C.2
  • 27
    • 79954556424 scopus 로고    scopus 로고
    • The Candida albicans-specific gene EED1 encodes a key regulator of hyphal extensio
    • Martin R, Moran GP, Jacobsen ID, Heyken A, Domey J, et al. (2011) The Candida albicans-specific gene EED1 encodes a key regulator of hyphal extension. PLoS One 6: e18394.
    • (2011) PLoS One , vol.6 , pp. 18394
    • Martin, R.1    Moran, G.P.2    Jacobsen, I.D.3    Heyken, A.4    Domey, J.5
  • 28
    • 4344613598 scopus 로고    scopus 로고
    • ALS3 and ALS8 represent a single locus that encodes a Candida albicans adhesin; functional comparisons between Als3p and Als1
    • Zhao X, Oh SH, Cheng G, Green CB, Nuessen JA, et al. (2004) ALS3 and ALS8 represent a single locus that encodes a Candida albicans adhesin; functional comparisons between Als3p and Als1p. Microbiology 150: 2415–2428.
    • (2004) Microbiology , vol.150 , pp. 2415-2428
    • Zhao, X.1    Oh, S.H.2    Cheng, G.3    Green, C.B.4    Nuessen, J.A.5
  • 29
    • 84856117019 scopus 로고    scopus 로고
    • A recently evolved transcriptional network controls biofilm development in Candida albican
    • Nobile CJ, Fox EP, Nett JE, Sorrells TR, Mitrovich QM, et al. (2012) A recently evolved transcriptional network controls biofilm development in Candida albicans. Cell 148: 126–138.
    • (2012) Cell , vol.148 , pp. 126-138
    • Nobile, C.J.1    Fox, E.P.2    Nett, J.E.3    Sorrells, T.R.4    Mitrovich, Q.M.5
  • 30
    • 0032746554 scopus 로고    scopus 로고
    • Filamentous growth of Candida albicans in response to physical environmental cues and its regulation by the unique CZF1 gen
    • Brown DH, JrGiusani AD, Chen X, Kumamoto CA, (1999) Filamentous growth of Candida albicans in response to physical environmental cues and its regulation by the unique CZF1 gene. Mol Microbiol 34: 651–662.
    • (1999) Mol Microbiol , vol.34 , pp. 651-662
    • Brown, D.H.1    Giusani, A.D.2    Chen, X.3    Kumamoto, C.A.4
  • 31
    • 44949243150 scopus 로고    scopus 로고
    • UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulenc
    • Banerjee M, Thompson DS, Lazzell A, Carlisle PL, Pierce C, et al. (2008) UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulence. Mol Biol Cell 19: 1354–1365.
    • (2008) Mol Biol Cell , vol.19 , pp. 1354-1365
    • Banerjee, M.1    Thompson, D.S.2    Lazzell, A.3    Carlisle, P.L.4    Pierce, C.5
  • 32
    • 84856650946 scopus 로고    scopus 로고
    • Transcription factor Efg1 shows a haploinsufficiency phenotype in modulating the cell wall architecture and immunogenicity of Candida albican
    • Zavrel M, Majer O, Kuchler K, Rupp S, (2012) Transcription factor Efg1 shows a haploinsufficiency phenotype in modulating the cell wall architecture and immunogenicity of Candida albicans. Eukaryot Cell 11: 129–140.
    • (2012) Eukaryot Cell , vol.11 , pp. 129-140
    • Zavrel, M.1    Majer, O.2    Kuchler, K.3    Rupp, S.4
  • 33
    • 84865307122 scopus 로고    scopus 로고
    • Importance of the Candida albicans cell wall during commensalism and infectio
    • Gow NA, Hube B, (2012) Importance of the Candida albicans cell wall during commensalism and infection. Curr Opin Microbiol 15: 406–412.
    • (2012) Curr Opin Microbiol , vol.15 , pp. 406-412
    • Gow, N.A.1    Hube, B.2
  • 34
    • 32944472993 scopus 로고    scopus 로고
    • The Cek1 and Hog1 mitogen-activated protein kinases play complementary roles in cell wall biogenesis and chlamydospore formation in the fungal pathogen Candida albican
    • Eisman B, Alonso-Monge R, Roman E, Arana D, Nombela C, et al. (2006) The Cek1 and Hog1 mitogen-activated protein kinases play complementary roles in cell wall biogenesis and chlamydospore formation in the fungal pathogen Candida albicans. Eukaryot Cell 5: 347–358.
    • (2006) Eukaryot Cell , vol.5 , pp. 347-358
    • Eisman, B.1    Alonso-Monge, R.2    Roman, E.3    Arana, D.4    Nombela, C.5
  • 35
    • 0031888386 scopus 로고    scopus 로고
    • A role for the MAP kinase gene MKC1 in cell wall construction and morphological transitions in Candida albican
    • Navarro-Garcia F, Alonso-Monge R, Rico H, Pla J, Sentandreu R, et al. (1998) A role for the MAP kinase gene MKC1 in cell wall construction and morphological transitions in Candida albicans. Microbiology 144 (Pt 2) 411–424.
    • (1998) Microbiology , vol.144 , pp. 411-424
    • Navarro-Garcia, F.1    Alonso-Monge, R.2    Rico, H.3    Pla, J.4    Sentandreu, R.5
  • 36
    • 27944454229 scopus 로고    scopus 로고
    • The Sho1 adaptor protein links oxidative stress to morphogenesis and cell wall biosynthesis in the fungal pathogen Candida albican
    • Roman E, Nombela C, Pla J, (2005) The Sho1 adaptor protein links oxidative stress to morphogenesis and cell wall biosynthesis in the fungal pathogen Candida albicans. Mol Cell Biol 25: 10611–10627.
    • (2005) Mol Cell Biol , vol.25 , pp. 10611-10627
    • Roman, E.1    Nombela, C.2    Pla, J.3
  • 37
    • 78649240033 scopus 로고    scopus 로고
    • Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-se
    • Bruno VM, Wang Z, Marjani SL, Euskirchen GM, Martin J, et al. (2010) Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-seq. Genome Res 20: 1451–1458.
    • (2010) Genome Res , vol.20 , pp. 1451-1458
    • Bruno, V.M.1    Wang, Z.2    Marjani, S.L.3    Euskirchen, G.M.4    Martin, J.5
  • 38
    • 84875045541 scopus 로고    scopus 로고
    • A core filamentation response network in Candida albicans is restricted to eight gene
    • Martin R, Albrecht-Eckardt D, Brunke S, Hube B, Hünniger K, et al. (2013) A core filamentation response network in Candida albicans is restricted to eight genes. PLoS One 8: e58613.
    • (2013) PLoS One , vol.8 , pp. 58613
    • Martin, R.1    Albrecht-Eckardt, D.2    Brunke, S.3    Hube, B.4    Hünniger, K.5
  • 39
    • 84871996857 scopus 로고    scopus 로고
    • Normal adaptation of Candida albicans to the murine gastrointestinal tract requires Efg1p-dependent regulation of metabolic and host defense gene
    • Pierce JV, Dignard D, Whiteway M, Kumamoto CA, (2013) Normal adaptation of Candida albicans to the murine gastrointestinal tract requires Efg1p-dependent regulation of metabolic and host defense genes. Eukaryot Cell 12: 37–49.
    • (2013) Eukaryot Cell , vol.12 , pp. 37-49
    • Pierce, J.V.1    Dignard, D.2    Whiteway, M.3    Kumamoto, C.A.4
  • 40
    • 84877994942 scopus 로고    scopus 로고
    • Human serum promotes Candida albicans biofilm growth and virulence gene expression on silicone biomateria
    • Samaranayake YH, Cheung BP, Yau JY, Yeung SK, Samaranayake LP, (2013) Human serum promotes Candida albicans biofilm growth and virulence gene expression on silicone biomaterial. PLoS One 8: e62902.
    • (2013) PLoS One , vol.8 , pp. 62902
    • Samaranayake, Y.H.1    Cheung, B.P.2    Yau, J.Y.3    Yeung, S.K.4    Samaranayake, L.P.5
  • 41
    • 77953523119 scopus 로고    scopus 로고
    • The Candida albicans ELMO homologue functions together with Rac1 and Dck1, upstream of the MAP Kinase Cek1, in invasive filamentous growt
    • Hope H, Schmauch C, Arkowitz RA, Bassilana M, (2010) The Candida albicans ELMO homologue functions together with Rac1 and Dck1, upstream of the MAP Kinase Cek1, in invasive filamentous growth. Mol Microbiol 76: 1572–1590.
    • (2010) Mol Microbiol , vol.76 , pp. 1572-1590
    • Hope, H.1    Schmauch, C.2    Arkowitz, R.A.3    Bassilana, M.4
  • 42
    • 0035801610 scopus 로고    scopus 로고
    • NRG1, a repressor of filamentous growth in C.albicans, is down-regulated during filament inductio
    • Braun BR, Kadosh D, Johnson AD, (2001) NRG1, a repressor of filamentous growth in C.albicans, is down-regulated during filament induction. Embo J 20: 4753–4761.
    • (2001) Embo J , vol.20 , pp. 4753-4761
    • Braun, B.R.1    Kadosh, D.2    Johnson, A.D.3
  • 43
    • 17944370004 scopus 로고    scopus 로고
    • NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albican
    • Murad AM, Leng P, Straffon M, Wishart J, Macaskill S, et al. (2001) NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans. Embo J 20: 4742–4752.
    • (2001) Embo J , vol.20 , pp. 4742-4752
    • Murad, A.M.1    Leng, P.2    Straffon, M.3    Wishart, J.4    Macaskill, S.5
  • 44
    • 80052563657 scopus 로고    scopus 로고
    • Stress alters rates and types of loss of heterozygosity in Candida albican
    • Forche A, Abbey D, Pisithkul T, Weinzierl MA, Ringstrom T, et al. (2011) Stress alters rates and types of loss of heterozygosity in Candida albicans. MBio 2.
    • (2011) MBio , vol.2
    • Forche, A.1    Abbey, D.2    Pisithkul, T.3    Weinzierl, M.A.4    Ringstrom, T.5
  • 45
    • 70349682086 scopus 로고    scopus 로고
    • Efficient and rapid identification of Candida albicans allelic status using SNP-RFL
    • Forche A, Steinbach M, Berman J, (2009) Efficient and rapid identification of Candida albicans allelic status using SNP-RFLP. FEMS Yeast Res 9: 1061–1069.
    • (2009) FEMS Yeast Res , vol.9 , pp. 1061-1069
    • Forche, A.1    Steinbach, M.2    Berman, J.3
  • 46
    • 0027192868 scopus 로고
    • Isogenic strain construction and gene mapping in Candida albican
    • Fonzi WA, Irwin MY, (1993) Isogenic strain construction and gene mapping in Candida albicans. Genetics 134: 717–728.
    • (1993) Genetics , vol.134 , pp. 717-728
    • Fonzi, W.A.1    Irwin, M.Y.2
  • 47
    • 0034653201 scopus 로고    scopus 로고
    • CIp10, an efficient and convenient integrating vector for Candida albican
    • Murad AM, Lee PR, Broadbent ID, Barelle CJ, Brown AJ, (2000) CIp10, an efficient and convenient integrating vector for Candida albicans. Yeast 16: 325–327.
    • (2000) Yeast , vol.16 , pp. 325-327
    • Murad, A.M.1    Lee, P.R.2    Broadbent, I.D.3    Barelle, C.J.4    Brown, A.J.5
  • 48
    • 84862232618 scopus 로고    scopus 로고
    • The Candida genome database incorporates multiple Candida species: multispecies search and analysis tools with curated gene and protein information for Candida albicans and Candida glabrat
    • Inglis DO, Arnaud MB, Binkley J, Shah P, Skrzypek MS, et al. (2012) The Candida genome database incorporates multiple Candida species: multispecies search and analysis tools with curated gene and protein information for Candida albicans and Candida glabrata. Nucleic Acids Res 40: D667–674.
    • (2012) Nucleic Acids Res , vol.40 , pp. D667-674
    • Inglis, D.O.1    Arnaud, M.B.2    Binkley, J.3    Shah, P.4    Skrzypek, M.S.5
  • 49
    • 0035313659 scopus 로고    scopus 로고
    • The ALS gene family of Candida albican
    • Hoyer LL, (2001) The ALS gene family of Candida albicans. Trends Microbiol 9: 176–180.
    • (2001) Trends Microbiol , vol.9 , pp. 176-180
    • Hoyer, L.L.1
  • 50
    • 0029038690 scopus 로고
    • Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeas
    • Kuchin S, Yeghiayan P, Carlson M, (1995) Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast. Proc Natl Acad Sci U S A 92: 4006–4010.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 4006-4010
    • Kuchin, S.1    Yeghiayan, P.2    Carlson, M.3
  • 51
    • 0037426868 scopus 로고    scopus 로고
    • Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste1
    • Nelson C, Goto S, Lund K, Hung W, Sadowski I, (2003) Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12. Nature 421: 187–190.
    • (2003) Nature , vol.421 , pp. 187-190
    • Nelson, C.1    Goto, S.2    Lund, K.3    Hung, W.4    Sadowski, I.5
  • 52
    • 4444353636 scopus 로고    scopus 로고
    • Regulation of protein kinases; controlling activity through activation segment conformatio
    • Nolen B, Taylor S, Ghosh G, (2004) Regulation of protein kinases; controlling activity through activation segment conformation. Mol Cell 15: 661–675.
    • (2004) Mol Cell , vol.15 , pp. 661-675
    • Nolen, B.1    Taylor, S.2    Ghosh, G.3
  • 53
    • 5044225522 scopus 로고    scopus 로고
    • The SAT1 flipper, an optimized tool for gene disruption in Candida albican
    • Reuss O, Vik A, Kolter R, Morschhauser J, (2004) The SAT1 flipper, an optimized tool for gene disruption in Candida albicans. Gene 341: 119–127.
    • (2004) Gene , vol.341 , pp. 119-127
    • Reuss, O.1    Vik, A.2    Kolter, R.3    Morschhauser, J.4
  • 54
    • 73449107205 scopus 로고    scopus 로고
    • Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistanc
    • Selmecki AM, Dulmage K, Cowen LE, Anderson JB, Berman J, (2009) Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance. PLoS Genet 5: e1000705.
    • (2009) PLoS Genet , vol.5 , pp. 1000705
    • Selmecki, A.M.1    Dulmage, K.2    Cowen, L.E.3    Anderson, J.B.4    Berman, J.5
  • 55
    • 0028569082 scopus 로고
    • Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolo
    • Liu H, Köhler J, Fink GR, (1994) Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog. Science 266: 1723–1726.
    • (1994) Science , vol.266 , pp. 1723-1726
    • Liu, H.1    Köhler, J.2    Fink, G.R.3
  • 56
    • 0035053398 scopus 로고    scopus 로고
    • A potential phosphorylation site for an A-type kinase in the Efg1 regulator protein contributes to hyphal morphogenesis of Candida albican
    • Bockmühl DP, Ernst JF, (2001) A potential phosphorylation site for an A-type kinase in the Efg1 regulator protein contributes to hyphal morphogenesis of Candida albicans. Genetics 157: 1523–1530.
    • (2001) Genetics , vol.157 , pp. 1523-1530
    • Bockmühl, D.P.1    Ernst, J.F.2
  • 57
    • 10544224146 scopus 로고    scopus 로고
    • Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albican
    • Leberer E, Harcus D, Broadbent ID, Clark KL, Dignard D, et al. (1996) Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans. Proc Natl Acad Sci U S A 93: 13217–13222.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 13217-13222
    • Leberer, E.1    Harcus, D.2    Broadbent, I.D.3    Clark, K.L.4    Dignard, D.5
  • 58
    • 0142074768 scopus 로고    scopus 로고
    • The cAMP phosphodiesterase encoded by CaPDE2 is required for hyphal development in Candida albican
    • Jung WH, Stateva LI, (2003) The cAMP phosphodiesterase encoded by CaPDE2 is required for hyphal development in Candida albicans. Microbiology 149: 2961–2976.
    • (2003) Microbiology , vol.149 , pp. 2961-2976
    • Jung, W.H.1    Stateva, L.I.2
  • 59
    • 0032213222 scopus 로고    scopus 로고
    • N-acetyl-D-glucosamine induces germination in Candida albicans through a mechanism sensitive to inhibitors of cAMP-dependent protein kinas
    • Castilla R, Passeron S, Cantore ML, (1998) N-acetyl-D-glucosamine induces germination in Candida albicans through a mechanism sensitive to inhibitors of cAMP-dependent protein kinase. Cell Signal 10: 713–719.
    • (1998) Cell Signal , vol.10 , pp. 713-719
    • Castilla, R.1    Passeron, S.2    Cantore, M.L.3
  • 60
    • 27844459081 scopus 로고    scopus 로고
    • 2 sensing with cAMP signaling and virulenc
    • Klengel T, Liang WJ, Chaloupka J, Ruoff C, Schröppel K, et al. (2005) Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence. Curr Biol 15: 2021–2026.
    • (2005) Curr Biol , vol.15 , pp. 2021-2026
    • Klengel, T.1    Liang, W.J.2    Chaloupka, J.3    Ruoff, C.4    Schröppel, K.5
  • 61
    • 68849099102 scopus 로고    scopus 로고
    • The Cek1 MAPK is a short-lived protein regulated by quorum sensing in the fungal pathogen Candida albican
    • Roman E, Alonso-Monge R, Gong Q, Li D, Calderone R, et al. (2009) The Cek1 MAPK is a short-lived protein regulated by quorum sensing in the fungal pathogen Candida albicans. FEMS Yeast Res 9: 942–955.
    • (2009) FEMS Yeast Res , vol.9 , pp. 942-955
    • Roman, E.1    Alonso-Monge, R.2    Gong, Q.3    Li, D.4    Calderone, R.5
  • 62
    • 36849075751 scopus 로고    scopus 로고
    • Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesi
    • Davis-Hanna A, Piispanen AE, Stateva LI, Hogan DA, (2008) Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis. Mol Microbiol 67: 47–62.
    • (2008) Mol Microbiol , vol.67 , pp. 47-62
    • Davis-Hanna, A.1    Piispanen, A.E.2    Stateva, L.I.3    Hogan, D.A.4
  • 63
    • 79960921059 scopus 로고    scopus 로고
    • Hyphal development in Candida albicans requires two temporally linked changes in promoter chromatin for initiation and maintenanc
    • Lu Y, Su C, Wang A, Liu H, (2011) Hyphal development in Candida albicans requires two temporally linked changes in promoter chromatin for initiation and maintenance. PLoS Biol 9: e1001105.
    • (2011) PLoS Biol , vol.9 , pp. 1001105
    • Lu, Y.1    Su, C.2    Wang, A.3    Liu, H.4
  • 64
    • 35948998096 scopus 로고    scopus 로고
    • In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial disseminatio
    • Zakikhany K, Naglik JR, Schmidt-Westhausen A, Holland G, Schaller M, et al. (2007) In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination. Cell Microbiol 9: 2938–2954.
    • (2007) Cell Microbiol , vol.9 , pp. 2938-2954
    • Zakikhany, K.1    Naglik, J.R.2    Schmidt-Westhausen, A.3    Holland, G.4    Schaller, M.5
  • 65
    • 23844552138 scopus 로고    scopus 로고
    • The MAP kinase Mkc1p is activated under different stress conditions in Candida albican
    • Navarro-Garcia F, Eisman B, Fiuza SM, Nombela C, Pla J, (2005) The MAP kinase Mkc1p is activated under different stress conditions in Candida albicans. Microbiology 151: 2737–2749.
    • (2005) Microbiology , vol.151 , pp. 2737-2749
    • Navarro-Garcia, F.1    Eisman, B.2    Fiuza, S.M.3    Nombela, C.4    Pla, J.5
  • 66
    • 77950241674 scopus 로고    scopus 로고
    • Candida albicans beta-glucan exposure is controlled by the fungal CEK1-mediated mitogen-activated protein kinase pathway that modulates immune responses triggered through dectin-
    • Galán-Diez M, Arana DM, Serrano-Gomez D, Kremer L, Casasnovas JM, et al. (2010) Candida albicans beta-glucan exposure is controlled by the fungal CEK1-mediated mitogen-activated protein kinase pathway that modulates immune responses triggered through dectin-1. Infect Immun 78: 1426–1436.
    • (2010) Infect Immun , vol.78 , pp. 1426-1436
    • Galán-Diez, M.1    Arana, D.M.2    Serrano-Gomez, D.3    Kremer, L.4    Casasnovas, J.M.5
  • 67
    • 0033710445 scopus 로고    scopus 로고
    • The TEA/ATTS transcription factor CaTec1p regulates hyphal development and virulence in Candida albican
    • Schweizer A, Rupp S, Taylor BN, Rollinghoff M, Schröppel K, (2000) The TEA/ATTS transcription factor CaTec1p regulates hyphal development and virulence in Candida albicans. Mol Microbiol 38: 435–445.
    • (2000) Mol Microbiol , vol.38 , pp. 435-445
    • Schweizer, A.1    Rupp, S.2    Taylor, B.N.3    Rollinghoff, M.4    Schröppel, K.5
  • 68
    • 84864086156 scopus 로고    scopus 로고
    • BRG1 and NRG1 form a novel feedback circuit regulating Candida albicans hypha formation and virulenc
    • Cleary IA, Lazzell AL, Monteagudo C, Thomas DP, Saville SP, (2012) BRG1 and NRG1 form a novel feedback circuit regulating Candida albicans hypha formation and virulence. Mol Microbiol 85: 557–573.
    • (2012) Mol Microbiol , vol.85 , pp. 557-573
    • Cleary, I.A.1    Lazzell, A.L.2    Monteagudo, C.3    Thomas, D.P.4    Saville, S.P.5
  • 69
    • 58149339808 scopus 로고    scopus 로고
    • UME6 is a crucial downstream target of other transcriptional regulators of true hyphal development in Candida albican
    • Zeidler U, Lettner T, Lassnig C, Müller M, Lajko R, et al. (2009) UME6 is a crucial downstream target of other transcriptional regulators of true hyphal development in Candida albicans. FEMS Yeast Res 9: 126–142.
    • (2009) FEMS Yeast Res , vol.9 , pp. 126-142
    • Zeidler, U.1    Lettner, T.2    Lassnig, C.3    Müller, M.4    Lajko, R.5
  • 70
    • 0033985662 scopus 로고    scopus 로고
    • RIM101-dependent and-independent pathways govern pH responses in Candida albican
    • Davis D, Wilson RB, Mitchell AP, (2000) RIM101-dependent and-independent pathways govern pH responses in Candida albicans. Mol Cell Biol 20: 971–978.
    • (2000) Mol Cell Biol , vol.20 , pp. 971-978
    • Davis, D.1    Wilson, R.B.2    Mitchell, A.P.3
  • 71
    • 50349084644 scopus 로고    scopus 로고
    • Impact of the unfolded protein response upon genome-wide expression patterns, and the role of Hac1 in the polarized growth, of Candida albican
    • Wimalasena TT, Enjalbert B, Guillemette T, Plumridge A, Budge S, et al. (2008) Impact of the unfolded protein response upon genome-wide expression patterns, and the role of Hac1 in the polarized growth, of Candida albicans. Fungal Genet Biol 45: 1235–1247.
    • (2008) Fungal Genet Biol , vol.45 , pp. 1235-1247
    • Wimalasena, T.T.1    Enjalbert, B.2    Guillemette, T.3    Plumridge, A.4    Budge, S.5
  • 72
    • 0032880015 scopus 로고    scopus 로고
    • HWP1 functions in the morphological development of Candida albicans downstream of EFG1, TUP1, and RBF
    • Sharkey LL, McNemar MD, Saporito-Irwin SM, Sypherd PS, Fonzi WA, (1999) HWP1 functions in the morphological development of Candida albicans downstream of EFG1, TUP1, and RBF1. J Bacteriol 181: 5273–5279.
    • (1999) J Bacteriol , vol.181 , pp. 5273-5279
    • Sharkey, L.L.1    McNemar, M.D.2    Saporito-Irwin, S.M.3    Sypherd, P.S.4    Fonzi, W.A.5
  • 73
    • 41749113291 scopus 로고    scopus 로고
    • An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC
    • Selmecki A, Gerami-Nejad M, Paulson C, Forche A, Berman J, (2008) An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1. Mol Microbiol 68: 624–641.
    • (2008) Mol Microbiol , vol.68 , pp. 624-641
    • Selmecki, A.1    Gerami-Nejad, M.2    Paulson, C.3    Forche, A.4    Berman, J.5
  • 74
    • 70350017855 scopus 로고    scopus 로고
    • Widespread occurrence of chromosomal aneuploidy following the routine production of Candida albicans mutant
    • Arbour M, Epp E, Hogues H, Sellam A, Lacroix C, et al. (2009) Widespread occurrence of chromosomal aneuploidy following the routine production of Candida albicans mutants. FEMS Yeast Res 9: 1070–1077.
    • (2009) FEMS Yeast Res , vol.9 , pp. 1070-1077
    • Arbour, M.1    Epp, E.2    Hogues, H.3    Sellam, A.4    Lacroix, C.5
  • 75
    • 0141780881 scopus 로고    scopus 로고
    • Evaluation of the roles of four Candida albicans genes in virulence by using gene disruption strains that express URA3 from the native locu
    • Cheng S, Nguyen MH, Zhang Z, Jia H, Handfield M, et al. (2003) Evaluation of the roles of four Candida albicans genes in virulence by using gene disruption strains that express URA3 from the native locus. Infect Immun 71: 6101–6103.
    • (2003) Infect Immun , vol.71 , pp. 6101-6103
    • Cheng, S.1    Nguyen, M.H.2    Zhang, Z.3    Jia, H.4    Handfield, M.5
  • 76
    • 0036263539 scopus 로고    scopus 로고
    • Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locu
    • Sundstrom P, Cutler JE, Staab JF, (2002) Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus. Infect Immun 70: 3281–3283.
    • (2002) Infect Immun , vol.70 , pp. 3281-3283
    • Sundstrom, P.1    Cutler, J.E.2    Staab, J.F.3
  • 77
    • 17644366425 scopus 로고    scopus 로고
    • Flanking direct repeats of hisG alter URA3 marker expression at the HWP1 locus of Candida albican
    • Sharkey LL, Liao WL, Ghosh AK, Fonzi WA, (2005) Flanking direct repeats of hisG alter URA3 marker expression at the HWP1 locus of Candida albicans. Microbiology 151: 1061–1071.
    • (2005) Microbiology , vol.151 , pp. 1061-1071
    • Sharkey, L.L.1    Liao, W.L.2    Ghosh, A.K.3    Fonzi, W.A.4
  • 78
    • 0033786937 scopus 로고    scopus 로고
    • Mediator of transcriptional regulatio
    • Myers LC, Kornberg RD, (2000) Mediator of transcriptional regulation. Annu Rev Biochem 69: 729–749.
    • (2000) Annu Rev Biochem , vol.69 , pp. 729-749
    • Myers, L.C.1    Kornberg, R.D.2
  • 79
    • 0141725524 scopus 로고    scopus 로고
    • The mediator coactivator complex: functional and physical roles in transcriptional regulatio
    • Lewis BA, Reinberg D, (2003) The mediator coactivator complex: functional and physical roles in transcriptional regulation. J Cell Sci 116: 3667–3675.
    • (2003) J Cell Sci , vol.116 , pp. 3667-3675
    • Lewis, B.A.1    Reinberg, D.2
  • 80
    • 84856786805 scopus 로고    scopus 로고
    • Cdk8 regulates stability of the transcription factor Phd1 to control pseudohyphal differentiation of Saccharomyces cerevisia
    • Raithatha S, Su TC, Lourenco P, Goto S, Sadowski I, (2012) Cdk8 regulates stability of the transcription factor Phd1 to control pseudohyphal differentiation of Saccharomyces cerevisiae. Mol Cell Biol 32: 664–674.
    • (2012) Mol Cell Biol , vol.32 , pp. 664-674
    • Raithatha, S.1    Su, T.C.2    Lourenco, P.3    Goto, S.4    Sadowski, I.5
  • 81
    • 0041311216 scopus 로고    scopus 로고
    • The cyclin in the RNA polymerase holoenzyme is a target for the transcriptional repressor Tup1p in Saccharomyces cerevisia
    • Schüller J, Lehming N, (2003) The cyclin in the RNA polymerase holoenzyme is a target for the transcriptional repressor Tup1p in Saccharomyces cerevisiae. J Mol Microbiol Biotechnol 5: 199–205.
    • (2003) J Mol Microbiol Biotechnol , vol.5 , pp. 199-205
    • Schüller, J.1    Lehming, N.2
  • 82
    • 4344672753 scopus 로고    scopus 로고
    • Promoter-dependent roles for the Srb10 cyclin-dependent kinase and the Hda1 deacetylase in Tup1-mediated repression in Saccharomyces cerevisia
    • Green SR, Johnson AD, (2004) Promoter-dependent roles for the Srb10 cyclin-dependent kinase and the Hda1 deacetylase in Tup1-mediated repression in Saccharomyces cerevisiae. Mol Biol Cell 15: 4191–4202.
    • (2004) Mol Biol Cell , vol.15 , pp. 4191-4202
    • Green, S.R.1    Johnson, A.D.2
  • 83
    • 0031886049 scopus 로고    scopus 로고
    • Functional relationships of Srb10-Srb11 kinase, carboxy-terminal domain kinase CTDK-I, and transcriptional corepressor Ssn6-Tup
    • Kuchin S, Carlson M, (1998) Functional relationships of Srb10-Srb11 kinase, carboxy-terminal domain kinase CTDK-I, and transcriptional corepressor Ssn6-Tup1. Mol Cell Biol 18: 1163–1171.
    • (1998) Mol Cell Biol , vol.18 , pp. 1163-1171
    • Kuchin, S.1    Carlson, M.2
  • 84
    • 0013329665 scopus 로고    scopus 로고
    • Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisia
    • Park SH, Koh SS, Chun JH, Hwang HJ, Kang HS, (1999) Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisiae. Mol Cell Biol 19: 2044–2050.
    • (1999) Mol Cell Biol , vol.19 , pp. 2044-2050
    • Park, S.H.1    Koh, S.S.2    Chun, J.H.3    Hwang, H.J.4    Kang, H.S.5
  • 85
    • 3042760385 scopus 로고    scopus 로고
    • The Ras/PKA signaling pathway directly targets the Srb9 protein, a component of the general RNA polymerase II transcription apparatu
    • Chang YW, Howard SC, Herman PK, (2004) The Ras/PKA signaling pathway directly targets the Srb9 protein, a component of the general RNA polymerase II transcription apparatus. Mol Cell 15: 107–116.
    • (2004) Mol Cell , vol.15 , pp. 107-116
    • Chang, Y.W.1    Howard, S.C.2    Herman, P.K.3
  • 86
    • 84908346385 scopus 로고    scopus 로고
    • Brunke S, Seider K, Fischer D, Jacobsen ID, Kasper L, et al. (2014) One Small Step for a Yeast - Microevolution within Macrophages Renders Candida glabrata Hypervirulent Due to a Single Point Mutatio
    • Brunke S, Seider K, Fischer D, Jacobsen I, Kasper L, et al. (2014) Brunke S, Seider K, Fischer D, Jacobsen ID, Kasper L, et al. (2014) One Small Step for a Yeast - Microevolution within Macrophages Renders Candida glabrata Hypervirulent Due to a Single Point Mutation. PLoS Pathog 10 (10) e1004478 doi:10.1371/journal.ppat.1004478
    • (2014) PLoS Pathog , vol.10 , Issue.10 , pp. 1004478
    • Brunke, S.1    Seider, K.2    Fischer, D.3    Jacobsen, I.4    Kasper, L.5
  • 87
    • 84861205386 scopus 로고    scopus 로고
    • The novel Candida albicans transporter Dur31 Is a multi-stage pathogenicity facto
    • Mayer FL, Wilson D, Jacobsen ID, Miramón P, Grosse K, et al. (2012) The novel Candida albicans transporter Dur31 Is a multi-stage pathogenicity factor. PLoS Pathog 8: e1002592.
    • (2012) PLoS Pathog , vol.8 , pp. 1002592
    • Mayer, F.L.1    Wilson, D.2    Jacobsen, I.D.3    Miramón, P.4    Grosse, K.5
  • 88
    • 0035710746 scopus 로고    scopus 로고
    • −ΔCT Metho
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔCT Method. Methods 25: 402–408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 89
    • 79960698975 scopus 로고    scopus 로고
    • Btrim: a fast, lightweight adapter and quality trimming program for next-generation sequencing technologie
    • Kong Y, (2011) Btrim: a fast, lightweight adapter and quality trimming program for next-generation sequencing technologies. Genomics 98: 152–153.
    • (2011) Genomics , vol.98 , pp. 152-153
    • Kong, Y.1
  • 90
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Se
    • Trapnell C, Pachter L, Salzberg SL, (2009) TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25: 1105–1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 91
    • 75249087100 scopus 로고    scopus 로고
    • edgeR: a Bioconductor package for differential expression analysis of digital gene expression dat
    • Robinson MD, McCarthy DJ, Smyth GK, (2010) edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26: 139–140.
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 92
    • 77958471357 scopus 로고    scopus 로고
    • Differential expression analysis for sequence count dat
    • Anders S, Huber W, (2010) Differential expression analysis for sequence count data. Genome Biol 11: R106.
    • (2010) Genome Biol , vol.11 , pp. R106
    • Anders, S.1    Huber, W.2
  • 93
    • 80053946203 scopus 로고    scopus 로고
    • SiTaR: a novel tool for transcription factor binding site predictio
    • Fazius E, Shelest V, Shelest E, (2011) SiTaR: a novel tool for transcription factor binding site prediction. Bioinformatics 27: 2806–2811.
    • (2011) Bioinformatics , vol.27 , pp. 2806-2811
    • Fazius, E.1    Shelest, V.2    Shelest, E.3
  • 95
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transfor
    • Li H, Durbin R, (2009) Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25: 1754–1760.
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 96
    • 80054078476 scopus 로고    scopus 로고
    • Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omeg
    • Sievers F, Wilm A, Dineen D, Gibson TJ, Karplus K, et al. (2011) Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Mol Syst Biol 7: 539.
    • (2011) Mol Syst Biol , vol.7 , pp. 539
    • Sievers, F.1    Wilm, A.2    Dineen, D.3    Gibson, T.J.4    Karplus, K.5
  • 97
    • 57149099394 scopus 로고    scopus 로고
    • Sequencing of natural strains of Arabidopsis thaliana with short read
    • Ossowski S, Schneeberger K, Clark RM, Lanz C, Warthmann N, et al. (2008) Sequencing of natural strains of Arabidopsis thaliana with short reads. Genome Res 18: 2024–2033.
    • (2008) Genome Res , vol.18 , pp. 2024-2033
    • Ossowski, S.1    Schneeberger, K.2    Clark, R.M.3    Lanz, C.4    Warthmann, N.5
  • 98
    • 0034618762 scopus 로고    scopus 로고
    • TFIIH is negatively regulated by cdk8-containing mediator complexe
    • Akoulitchev S, Chuikov S, Reinberg D, (2000) TFIIH is negatively regulated by cdk8-containing mediator complexes. Nature 407: 102–106.
    • (2000) Nature , vol.407 , pp. 102-106
    • Akoulitchev, S.1    Chuikov, S.2    Reinberg, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.