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Volumn 16, Issue 8, 1997, Pages 1982-1991

Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi

Author keywords

Candida albicans; Helix loop helix proteins; Morphogenesis; Transcription factor; Yeast

Indexed keywords

FUNGAL PROTEIN; HELIX LOOP HELIX PROTEIN; THREONINE; TRANSCRIPTION FACTOR;

EID: 0030945488     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.8.1982     Document Type: Article
Times cited : (536)

References (48)
  • 1
    • 0027431276 scopus 로고
    • A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation
    • Ayer, D.E. and Eisenman, R.N. (1993) A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation. Genes Dev., 7, 2110-2119.
    • (1993) Genes Dev. , vol.7 , pp. 2110-2119
    • Ayer, D.E.1    Eisenman, R.N.2
  • 2
    • 0028905563 scopus 로고
    • Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3
    • Ayer, D.E., Lawrence, Q.A. and Eisenman, R.N. (1995) Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell, 80, 767-776.
    • (1995) Cell , vol.80 , pp. 767-776
    • Ayer, D.E.1    Lawrence, Q.A.2    Eisenman, R.N.3
  • 3
    • 84907126545 scopus 로고
    • Phagocytosis of Candida albicans by rabbit alveolar macrophages and guinea pig neutrophils
    • Arai, T., Mikami, Y. and Yokoyama, K. (1977) Phagocytosis of Candida albicans by rabbit alveolar macrophages and guinea pig neutrophils. Sabouraudia, 15, 171-177.
    • (1977) Sabouraudia , vol.15 , pp. 171-177
    • Arai, T.1    Mikami, Y.2    Yokoyama, K.3
  • 4
    • 0029353422 scopus 로고
    • Flipping the Myc switch
    • Bernards, R. (1995) Flipping the Myc switch. Curr. Biol., 5, 859-861.
    • (1995) Curr. Biol. , vol.5 , pp. 859-861
    • Bernards, R.1
  • 5
    • 0027249418 scopus 로고
    • Regulation of dimorphism in S.cerevisiae: Involvement of a novel protein kinase homolog Elm1p and protein phosphatase 2A
    • Blacketer, M.J., Koehler, C.M., Coats, S.G., Myers, A.M. and Madaule, P. (1993) Regulation of dimorphism in S.cerevisiae: involvement of a novel protein kinase homolog Elm1p and protein phosphatase 2A. Mol. Cell. Biol., 13, 5567-5581.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5567-5581
    • Blacketer, M.J.1    Koehler, C.M.2    Coats, S.G.3    Myers, A.M.4    Madaule, P.5
  • 6
    • 0026061798 scopus 로고
    • Adherence and receptor relationships of Candida albicans
    • Calderone, R.A. and Braun, P. (1991) Adherence and receptor relationships of Candida albicans. Microbiol. Rev., 55, 1-20.
    • (1991) Microbiol. Rev. , vol.55 , pp. 1-20
    • Calderone, R.A.1    Braun, P.2
  • 7
    • 0026678112 scopus 로고
    • Cloning and expression of Candida albicans ADE2 and proteinase genes on a replicative plasmid in C. albicans and in Saccharomyces cerevisiae
    • Cannon, R.D., Jenkinson, H.F. and Shepherd, M.G. (1992). Cloning and expression of Candida albicans ADE2 and proteinase genes on a replicative plasmid in C. albicans and in Saccharomyces cerevisiae. Mol. Gen. Genet., 235, 453-457.
    • (1992) Mol. Gen. Genet. , vol.235 , pp. 453-457
    • Cannon, R.D.1    Jenkinson, H.F.2    Shepherd, M.G.3
  • 9
    • 0025989934 scopus 로고
    • Putative virulence factors of Candida albicans
    • Cutler, J.E. (1991) Putative virulence factors of Candida albicans. Annu. Rev. Microbiol., 45, 187-218.
    • (1991) Annu. Rev. Microbiol. , vol.45 , pp. 187-218
    • Cutler, J.E.1
  • 10
    • 0027525415 scopus 로고
    • Morphogenesis-independent regulation of actin transcript levels in the pathogenic yeast Candida albicans
    • Delbrück, S. and Ernst, J.F. (1993) Morphogenesis-independent regulation of actin transcript levels in the pathogenic yeast Candida albicans. Mol. Microbiol., 10, 859-866.
    • (1993) Mol. Microbiol. , vol.10 , pp. 859-866
    • Delbrück, S.1    Ernst, J.F.2
  • 11
    • 0028118685 scopus 로고
    • Getting a grip on DNa structures of the basic region leucine zipper, and the basic region helix-loop-helix DNA-binding domains
    • Ellenberger, T. (1994) Getting a grip on DNA structures of the basic region leucine zipper, and the basic region helix-loop-helix DNA-binding domains. Curr. Opin. Struct. Biol., 4, 12-21.
    • (1994) Curr. Opin. Struct. Biol. , vol.4 , pp. 12-21
    • Ellenberger, T.1
  • 12
    • 0027910469 scopus 로고
    • Recognition by Max of its cognate DNa through a dimeric b/HLH/Z domain
    • Ferré-D'Amare, A., Prendergast, G.C., Ziff, E.B. and Burley, S.K. (1993) Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain. Nature, 363, 38-45.
    • (1993) Nature , vol.363 , pp. 38-45
    • Ferré-D'Amare, A.1    Prendergast, G.C.2    Ziff, E.B.3    Burley, S.K.4
  • 13
    • 0026670518 scopus 로고
    • Single amino acid substitutions alter helix-loop-helix protein specificity for bases flanking the core CANNTG
    • Fisher, F. and Goding, C.R. (1992) Single amino acid substitutions alter helix-loop-helix protein specificity for bases flanking the core CANNTG. EMBO J., 11, 4103-4109.
    • (1992) EMBO J. , vol.11 , pp. 4103-4109
    • Fisher, F.1    Goding, C.R.2
  • 14
    • 0027192868 scopus 로고
    • Isogenic strain construction and gene mapping in Candida albicans
    • Fonzi, W.A. and Irwin, M.Y. (1993) Isogenic strain construction and gene mapping in Candida albicans. Genetics., 134, 717-728.
    • (1993) Genetics. , vol.134 , pp. 717-728
    • Fonzi, W.A.1    Irwin, M.Y.2
  • 16
    • 0024266139 scopus 로고
    • New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
    • Gietz, R.D. and Sugino, A. (1988) New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene, 74, 527-534.
    • (1988) Gene , vol.74 , pp. 527-534
    • Gietz, R.D.1    Sugino, A.2
  • 17
    • 0028265881 scopus 로고
    • Induction of pseudohyphal growth by overexpression of PHD1, a Saccharomyces cerevisiae gene related to transcriptional regulators of fungal development
    • Gimeno, C.J. and Fink, G.R. (1994) Induction of pseudohyphal growth by overexpression of PHD1, a Saccharomyces cerevisiae gene related to transcriptional regulators of fungal development. Mol. Biol. Cell, 14, 2100-2112.
    • (1994) Mol. Biol. Cell , vol.14 , pp. 2100-2112
    • Gimeno, C.J.1    Fink, G.R.2
  • 18
    • 0026588787 scopus 로고
    • Unipolar cell divisions in the yeast S.cerevisiae lead to filamentous growth: Regulation by starvation and RAS
    • Gimeno, C.J., Ljungdahl, P.O., Styles, C.A. and Fink, G.R. (1992) Unipolar cell divisions in the yeast S.cerevisiae lead to filamentous growth: regulation by starvation and RAS. Cell, 68, 1077-1090.
    • (1992) Cell , vol.68 , pp. 1077-1090
    • Gimeno, C.J.1    Ljungdahl, P.O.2    Styles, C.A.3    Fink, G.R.4
  • 19
    • 0022399096 scopus 로고
    • Each of three TATa elements specifies a subset of the transcription initiation sites at the CYC1 promoter of Saccharomyces cerevisiae
    • Hahn, S., Hoar, E.T. and Guarente, L. (1985) Each of three TATA elements specifies a subset of the transcription initiation sites at the CYC1 promoter of Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 82, 8562-8566.
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 8562-8566
    • Hahn, S.1    Hoar, E.T.2    Guarente, L.3
  • 20
    • 0025963054 scopus 로고
    • Putting the HO gene to work: Practical uses for mating-type switching
    • Herskowitz, I. and Jensen, R.E. (1991) Putting the HO gene to work: practical uses for mating-type switching. Methods Enzymol., 194, 132-146.
    • (1991) Methods Enzymol. , vol.194 , pp. 132-146
    • Herskowitz, I.1    Jensen, R.E.2
  • 21
    • 0025290642 scopus 로고
    • Do the poly(A) tail and 3′ untranslated region control mRNA translation?
    • Jackson, R.J. and Standar, N. (1990) Do the poly(A) tail and 3′ untranslated region control mRNA translation? Cell, 62, 15-24.
    • (1990) Cell , vol.62 , pp. 15-24
    • Jackson, R.J.1    Standar, N.2
  • 22
    • 0021471049 scopus 로고
    • Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae
    • Johnston, M. and Davis, R.W. (1984) Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol. Cell. Biol., 4, 1440-1448.
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 1440-1448
    • Johnston, M.1    Davis, R.W.2
  • 23
    • 0023074162 scopus 로고
    • Development of autonomously replicating plasmids for Candida albicans
    • Kurtz, M.B., Cortelyou, M.W., Miller, S.M. and Kirsch, D.R. (1987) Development of autonomously replicating plasmids for Candida albicans. Mol. Cell. Biol., 7, 209-217.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 209-217
    • Kurtz, M.B.1    Cortelyou, M.W.2    Miller, S.M.3    Kirsch, D.R.4
  • 24
    • 0028143121 scopus 로고
    • Toxicity of a heterologous leucyl-tRNa (anticodon CAG) in the pathogen Candida albicans: In vivo evidence for non-standard decoding of CUG codons
    • Leuker, C.E. and Ernst, J.F. (1994) Toxicity of a heterologous leucyl-tRNA (anticodon CAG) in the pathogen Candida albicans: in vivo evidence for non-standard decoding of CUG codons. Mol. Gen. Genet., 245, 212-217.
    • (1994) Mol. Gen. Genet. , vol.245 , pp. 212-217
    • Leuker, C.E.1    Ernst, J.F.2
  • 25
    • 0026619531 scopus 로고
    • β-galactosidase of Kluyveromyces lactis (Lac4p) as reporter of gene expression in Candida albicans and C. tropicalis
    • Leuker, C.E., Hahn, A.-M. and Ernst, J.F. (1992) β-galactosidase of Kluyveromyces lactis (Lac4p) as reporter of gene expression in Candida albicans and C. tropicalis. Mol. Gen. Genet., 235, 235-241.
    • (1992) Mol. Gen. Genet. , vol.235 , pp. 235-241
    • Leuker, C.E.1    Hahn, A.-M.2    Ernst, J.F.3
  • 26
    • 0028169192 scopus 로고
    • C-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II
    • Li, L., Nerlov, C., Predergast, G., MacGregor, D. and Ziff, E.B. (1994) c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II. EMBO J., 13, 4070-4079.
    • (1994) EMBO J. , vol.13 , pp. 4070-4079
    • Li, L.1    Nerlov, C.2    Predergast, G.3    MacGregor, D.4    Ziff, E.B.5
  • 27
    • 0027759277 scopus 로고
    • Elements of the yeast pheromone response pathway required for filamentous growth of diploids
    • Liu, H., Styles, C.A. and Fink, G.R. (1993) Elements of the yeast pheromone response pathway required for filamentous growth of diploids. Science, 262, 1741-1744.
    • (1993) Science , vol.262 , pp. 1741-1744
    • Liu, H.1    Styles, C.A.2    Fink, G.R.3
  • 28
    • 0028569082 scopus 로고
    • Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog
    • Liu, H., Köhler, J. and Fink, G.R. (1994) Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog. Science, 266, 1723-1725.
    • (1994) Science , vol.266 , pp. 1723-1725
    • Liu, H.1    Köhler, J.2    Fink, G.R.3
  • 29
    • 0024721370 scopus 로고
    • Sequence and transcript analysis of the C. albicans URA3 gene encoding orotidine-5′-phosphate decarboxylase
    • Losberger, C. and Ernst, J.F. (1989) Sequence and transcript analysis of the C. albicans URA3 gene encoding orotidine-5′-phosphate decarboxylase. Curr. Genet., 16, 153-157.
    • (1989) Curr. Genet. , vol.16 , pp. 153-157
    • Losberger, C.1    Ernst, J.F.2
  • 30
    • 0028215362 scopus 로고
    • Crystal structure of MyoD bHLH domain-DNA complex: Perspectives on DNA recognititon and implications for transcriptional activation
    • Ma, P.C.M., Rould, M.A., Weintraub, H. and Pabo, C.O. (1994) Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognititon and implications for transcriptional activation. Cell. 77, 451-459.
    • (1994) Cell. , vol.77 , pp. 451-459
    • Ma, P.C.M.1    Rould, M.A.2    Weintraub, H.3    Pabo, C.O.4
  • 31
    • 0024369757 scopus 로고
    • Dimorphism in Histoplasma capsulatum: A model for the study of cell differentiation in pathogenic fungi
    • Maresca, B. and Kobayashi, G.S. (1989) Dimorphism in Histoplasma capsulatum: a model for the study of cell differentiation in pathogenic fungi. Microbiol. Rev., 53, 186-209.
    • (1989) Microbiol. Rev. , vol.53 , pp. 186-209
    • Maresca, B.1    Kobayashi, G.S.2
  • 32
    • 0026658687 scopus 로고
    • StuA is required for cell pattern formation in Aspergillus
    • Miller, K.Y., Wu, J. and Miller, B.L. (1992) StuA is required for cell pattern formation in Aspergillus. Genes Dev., 6, 1770-1782
    • (1992) Genes Dev. , vol.6 , pp. 1770-1782
    • Miller, K.Y.1    Wu, J.2    Miller, B.L.3
  • 33
    • 0029895340 scopus 로고    scopus 로고
    • Ras2 signals via the Cdc42/Ste20/mitosen-activated kinase module to induce filamentous growth in Saccharomyces cerevisiae
    • Mösch, H.-U., Roberts, R. and Fink, G.R. (1996) Ras2 signals via the Cdc42/Ste20/mitosen-activated kinase module to induce filamentous growth in Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 93, 5352-5356.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 5352-5356
    • Mösch, H.-U.1    Roberts, R.2    Fink, G.R.3
  • 34
    • 0027443434 scopus 로고
    • The structure and function of yeast ARS elements
    • Newlon, C.S. and Theis, J.F. (1993). The structure and function of yeast ARS elements. Curr. Opin. Genet. Cell Biol., 3, 752-758.
    • (1993) Curr. Opin. Genet. Cell Biol. , vol.3 , pp. 752-758
    • Newlon, C.S.1    Theis, J.F.2
  • 36
    • 0021025179 scopus 로고
    • Genetic analysis of red, adenine-requiring mutants of Candida albicans
    • Poulter, R.T.M and Rikkerink, E.H. (1983) Genetic analysis of red, adenine-requiring mutants of Candida albicans. J. Bacteriol., 156, 1066-1077.
    • (1983) J. Bacteriol. , vol.156 , pp. 1066-1077
    • Poulter, R.T.M.1    Rikkerink, E.H.2
  • 37
    • 0025369859 scopus 로고
    • Activators and targets
    • Ptashne, M. and Gann, A.A.F. (1990) Activators and targets. Nature, 346, 329-331.
    • (1990) Nature , vol.346 , pp. 329-331
    • Ptashne, M.1    Gann, A.A.F.2
  • 38
    • 0026654255 scopus 로고
    • A G-protein α subunit from asexual Candida albicans functions in the mating pathway of Saccharomyces cerevisiae and is regulated by the a1-α2 reppressor
    • Sadhu, C., Hoekstra, D., McEachern, M.J., Reed, S.I. and Hicks, J.B. (1992) A G-protein α subunit from asexual Candida albicans functions in the mating pathway of Saccharomyces cerevisiae and is regulated by the a1-α2 reppressor. Mol. Cell. Biol., 12, 1977-1985.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1977-1985
    • Sadhu, C.1    Hoekstra, D.2    McEachern, M.J.3    Reed, S.I.4    Hicks, J.B.5
  • 40
    • 0029045375 scopus 로고
    • The CUG codon is decoded in vivo as serine and not leucine in Candida albicans
    • Santos, M.A.S. and Tuite, M.F. (1995) The CUG codon is decoded in vivo as serine and not leucine in Candida albicans. Nucleic Acids Res., 23, 1481-1486.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1481-1486
    • Santos, M.A.S.1    Tuite, M.F.2
  • 41
    • 0025034813 scopus 로고
    • The b alleles ot U.maydis, whose combinations program pathogenic development, code for polypeptides containing a homeodomain-related motif
    • Schulz, B., Banuett, F., Dahl, M., Schlesinger, R., Schäfer, W., Martin, T., Herskowitz, I. and Kahmann, R. (1990) The b alleles ot U.maydis, whose combinations program pathogenic development, code for polypeptides containing a homeodomain-related motif. Cell, 60, 295-306.
    • (1990) Cell , vol.60 , pp. 295-306
    • Schulz, B.1    Banuett, F.2    Dahl, M.3    Schlesinger, R.4    Schäfer, W.5    Martin, T.6    Herskowitz, I.7    Kahmann, R.8
  • 43
    • 0027153227 scopus 로고
    • High-frequency phenotypic switching in Candida albicans
    • Soll, D.R., Morrow, B. and Srikantha, T. (1993) High-frequency phenotypic switching in Candida albicans. Trends Genet., 9, 61-65.
    • (1993) Trends Genet. , vol.9 , pp. 61-65
    • Soll, D.R.1    Morrow, B.2    Srikantha, T.3
  • 44
    • 0028337542 scopus 로고
    • Transcriptional activation: A complex puzzle with few easy pieces
    • Tjian, R. and Maniatis, T. (1994) Transcriptional activation: a complex puzzle with few easy pieces. Cell, 77, 5-8.
    • (1994) Cell , vol.77 , pp. 5-8
    • Tjian, R.1    Maniatis, T.2
  • 45
    • 0028970369 scopus 로고
    • Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein
    • Treitel, M.A. and Carlson, M. (1995) Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein. Proc. Natl Acad. Sci. USA, 92, 3132-3136.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 3132-3136
    • Treitel, M.A.1    Carlson, M.2
  • 46
    • 0026641776 scopus 로고
    • Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection
    • Winston, F. and Carlson, M. (1992) Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection. Trends Genet., 8, 387-392.
    • (1992) Trends Genet. , vol.8 , pp. 387-392
    • Winston, F.1    Carlson, M.2
  • 47
    • 0028790841 scopus 로고    scopus 로고
    • SOK2 may regulate cyclic AMP-dependent protein kinase-stimulated growth and pseudohyphal development by repressing transcription
    • Ward, M.P., Gimeno, C.J., Fink, G.R. and Garrett, S. (1996) SOK2 may regulate cyclic AMP-dependent protein kinase-stimulated growth and pseudohyphal development by repressing transcription. Mol. Cell. Biol., 15, 6854-6863.
    • (1996) Mol. Cell. Biol. , vol.15 , pp. 6854-6863
    • Ward, M.P.1    Gimeno, C.J.2    Fink, G.R.3    Garrett, S.4
  • 48
    • 0020108296 scopus 로고
    • DNA sequence required for efficient transcription termination in yeast
    • Zaret, K.S. and Sherman, F. (1982) DNA sequence required for efficient transcription termination in yeast. Cell, 28, 563-573.
    • (1982) Cell , vol.28 , pp. 563-573
    • Zaret, K.S.1    Sherman, F.2


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