Candida albicans β-glucan exposure is controlled by the fungal CEK1-mediated mitogen-activated protein kinase pathway that modulates immune responses triggered through dectin-1

Infection and Immunity

Volumn 78, Issue 4, 2010, Pages 1426-1436

  Galán Díez, Marta ^a   Arana, David M ^b   Serrano Gómez, Diego ^a   Kremer, Leonor ^c   Casasnovas, José M ^c   Ortega, Mara ^a   Cuesta Domínguez, Álvaro ^a   Corbí, Angel L ^d   Pla, Jesús ^b   Fernández Ruiz, Elena ^a  

^a HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^d CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCAN; CYTOKINE; DECTIN 1; I KAPPA B; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE SYK; RAF PROTEIN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CANDIDA ALBICANS; CARBOHYDRATE ANALYSIS; CEK1 GENE; CELL ACTIVATION; CELL WALL; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; EMBRYO; ENZYME ACTIVATION; FUNGAL GENE; FUNGAL VIRULENCE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; MACROPHAGE; MOLECULAR RECOGNITION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; WILD TYPE;

BETA-GLUCANS; CANDIDA ALBICANS; CELL ADHESION; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; FUNGAL PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, FUNGAL; GENE KNOCKOUT TECHNIQUES; HUMANS; MACROPHAGES; MEMBRANE PROTEINS; MICROBIAL VIABILITY; MITOGEN-ACTIVATED PROTEIN KINASE 3; NERVE TISSUE PROTEINS; PHAGOCYTOSIS; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; SPLEEN;

EID: 77950241674     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00989-09     Document Type: Article

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