Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance

PLoS Genetics

Volumn 5, Issue 10, 2009, Pages

  Selmecki, Anna M ^a   Dulmage, Keely ^a   Cowen, Leah E ^b   Anderson, James B ^c   Berman, Judith ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; FLUCONAZOLE;

ANEUPLOIDY; ANTIFUNGAL RESISTANCE; ARTICLE; CANDIDA ALBICANS; CHROMOSOME REARRANGEMENT; DIPLOIDY; DRUG EXPOSURE; EVOLUTION; FUNGAL STRAIN; GENOMIC INSTABILITY; IN VITRO STUDY; ISOCHROMOSOME; KARYOTYPE; LONGITUDINAL STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHARMACOGENETICS; PREVALENCE; SUPERNUMERARY CHROMOSOME; TRISOMY; CHROMOSOME; DRUG EFFECT; GENETIC FITNESS; GENETICS; HUMAN; MOLECULAR EVOLUTION;

CANDIDA ALBICANS;

ANEUPLOIDY; CANDIDA ALBICANS; CHROMOSOMES, FUNGAL; DRUG RESISTANCE, FUNGAL; EVOLUTION, MOLECULAR; FLUCONAZOLE; GENETIC FITNESS; HUMANS;

EID: 73449107205     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000705     Document Type: Article

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