메뉴 건너뛰기




Volumn 341, Issue 1-2, 2004, Pages 119-127

The SAT1 flipper, an optimized tool for gene disruption in Candida albicans

Author keywords

base pairs; bp; C; Candida; Dominant selection marker; ECL; enhanced chemiluminescence; Eth; ethionine; FLP recombination target; FRT; Homozygous mutants; kb; Marker recycling; Nourseothricin resistance; Oligopeptide transporter; Targeted gene disruption

Indexed keywords

FUNGAL ENZYME; NOURSEOTHRICIN; PEPTIDE TRANSPORTER 1; RECOMBINASE; STREPTOTHRICIN ACETYLTRANSFERASE 1; UNCLASSIFIED DRUG;

EID: 5044225522     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2004.06.021     Document Type: Article
Times cited : (612)

References (33)
  • 2
    • 0035856576 scopus 로고    scopus 로고
    • Ura-status-dependent adhesion of Candida albicans mutants
    • Bain J.M., Stubberfield C., Gow N.A. Ura-status-dependent adhesion of Candida albicans mutants. FEMS Microbiol. Lett. 204:2001;323-328
    • (2001) FEMS Microbiol. Lett. , vol.204 , pp. 323-328
    • Bain, J.M.1    Stubberfield, C.2    Gow, N.A.3
  • 3
    • 0141780881 scopus 로고    scopus 로고
    • Evaluation of the roles of four Candida albicans genes in virulence by using gene disruption strains that express URA3 from the native locus
    • Cheng S., Nguyen M.H., Zhang Z., Jia H., Handfield M., Clancy C.J. Evaluation of the roles of four Candida albicans genes in virulence by using gene disruption strains that express URA3 from the native locus. Infect. Immun. 71:2003;6101-6103
    • (2003) Infect. Immun. , vol.71 , pp. 6101-6103
    • Cheng, S.1    Nguyen, M.H.2    Zhang, Z.3    Jia, H.4    Handfield, M.5    Clancy, C.J.6
  • 4
    • 0028895693 scopus 로고
    • Avirulence of Candida albicans auxotrophic mutants in a rat model of oropharyngeal candidiasis
    • Cole M.F., Bowen W.H., Zhao X.J., Cihlar R.L. Avirulence of Candida albicans auxotrophic mutants in a rat model of oropharyngeal candidiasis. FEMS Microbiol. Lett. 126:1995;177-180
    • (1995) FEMS Microbiol. Lett. , vol.126 , pp. 177-180
    • Cole, M.F.1    Bowen, W.H.2    Zhao, X.J.3    Cihlar, R.L.4
  • 5
    • 0027192868 scopus 로고
    • Isogenic strain construction and gene mapping in Candida albicans
    • Fonzi W.A., Irwin M.Y. Isogenic strain construction and gene mapping in Candida albicans. Genetics. 134:1993;717-728
    • (1993) Genetics , vol.134 , pp. 717-728
    • Fonzi, W.A.1    Irwin, M.Y.2
  • 7
    • 0021742042 scopus 로고
    • Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations
    • Gillum A.M., Tsay E.Y., Kirsch D.R. Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations. Mol. Gen. Genet. 198:1984;179-182
    • (1984) Mol. Gen. Genet. , vol.198 , pp. 179-182
    • Gillum, A.M.1    Tsay, E.Y.2    Kirsch, D.R.3
  • 8
    • 0024422573 scopus 로고
    • Nucleotide sequence of a plasmid born streptothricin-acetyl-transferase gene (sat-1)
    • Heim U., Tietze E., Weschke W., Tschäpe H., Wobus U. Nucleotide sequence of a plasmid born streptothricin-acetyl-transferase gene (sat-1). Nucleic Acids Res. 17:1989;7103
    • (1989) Nucleic Acids Res. , vol.17 , pp. 7103
    • Heim, U.1    Tietze, E.2    Weschke, W.3    Tschäpe, H.4    Wobus, U.5
  • 9
    • 0027940569 scopus 로고
    • Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans
    • Hube B., Monod M., Schofield D.A., Brown A.J., Gow N.A. Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans. Mol. Microbiol. 14:1994;87-99
    • (1994) Mol. Microbiol. , vol.14 , pp. 87-99
    • Hube, B.1    Monod, M.2    Schofield, D.A.3    Brown, A.J.4    Gow, N.A.5
  • 10
    • 0030884478 scopus 로고    scopus 로고
    • Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence
    • Hube B., Sanglard D., Odds F.C., Hess D., Monod M., Schafer W., Brown A.J., Gow N.A. Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence. Infect. Immun. 65:1997;3529-3538
    • (1997) Infect. Immun. , vol.65 , pp. 3529-3538
    • Hube, B.1    Sanglard, D.2    Odds, F.C.3    Hess, D.4    Monod, M.5    Schafer, W.6    Brown, A.J.7    Gow, N.A.8
  • 11
    • 0028940433 scopus 로고
    • The gene encoding streptothricin acetyltransferase (sat) as a selectable marker for Leishmania expression vectors
    • Joshi P.B., Webb J.R., Davies J.E., McMaster W.R. The gene encoding streptothricin acetyltransferase (sat) as a selectable marker for Leishmania expression vectors. Gene. 156:1995;145-149
    • (1995) Gene , vol.156 , pp. 145-149
    • Joshi, P.B.1    Webb, J.R.2    Davies, J.E.3    McMaster, W.R.4
  • 12
    • 0025851152 scopus 로고
    • Pathogenicity of Candida albicans auxotrophic mutants in experimental infections
    • Kirsch D.R., Whitney R.R. Pathogenicity of Candida albicans auxotrophic mutants in experimental infections. Infect. Immun. 59:1991;3297-3300
    • (1991) Infect. Immun. , vol.59 , pp. 3297-3300
    • Kirsch, D.R.1    Whitney, R.R.2
  • 13
    • 0030938651 scopus 로고    scopus 로고
    • Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid
    • Köhler G.A., White T.C., Agabian N. Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid. J. Bacteriol. 179:1997;2331-2338
    • (1997) J. Bacteriol. , vol.179 , pp. 2331-2338
    • Köhler, G.A.1    White, T.C.2    Agabian, N.3
  • 14
    • 0023857885 scopus 로고
    • Analysis of the nourseothricin-resistance gene (nat) of Streptomyces noursei
    • Krügel H., Fiedler G., Haupt I., Sarfert E., Simon H. Analysis of the nourseothricin-resistance gene (nat) of Streptomyces noursei. Gene. 62:1988;209-217
    • (1988) Gene , vol.62 , pp. 209-217
    • Krügel, H.1    Fiedler, G.2    Haupt, I.3    Sarfert, E.4    Simon, H.5
  • 15
    • 0032411941 scopus 로고    scopus 로고
    • Altered expression of selectable marker URA3 in gene-disrupted Candida albicans strains complicates interpretation of virulence studies
    • Lay J., Henry L.K., Clifford J., Koltin Y., Bulawa C.E., Becker J.M. Altered expression of selectable marker URA3 in gene-disrupted Candida albicans strains complicates interpretation of virulence studies. Infect. Immun. 66:1998;5301-5306
    • (1998) Infect. Immun. , vol.66 , pp. 5301-5306
    • Lay, J.1    Henry, L.K.2    Clifford, J.3    Koltin, Y.4    Bulawa, C.E.5    Becker, J.M.6
  • 16
    • 0027305455 scopus 로고
    • Stimuli that induce production of Candida albicans extracellular aspartyl proteinase
    • Lerner C.G., Goldman R.C. Stimuli that induce production of Candida albicans extracellular aspartyl proteinase. J. Gen. Microbiol. 139(Pt. 7):1993;1643-1651
    • (1993) J. Gen. Microbiol. , vol.139 , Issue.7 PART , pp. 1643-1651
    • Lerner, C.G.1    Goldman, R.C.2
  • 19
    • 0141789642 scopus 로고    scopus 로고
    • Candida albicans secreted aspartyl proteinases in virulence and pathogenesis
    • (table of contents)
    • Naglik J.R., Challacombe S.J., Hube B. Candida albicans secreted aspartyl proteinases in virulence and pathogenesis. Microbiol. Mol. Biol. Rev. 67:2003;400-428. (table of contents)
    • (2003) Microbiol. Mol. Biol. Rev. , vol.67 , pp. 400-428
    • Naglik, J.R.1    Challacombe, S.J.2    Hube, B.3
  • 20
    • 0021073779 scopus 로고
    • Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis
    • Norrander J., Kempe T., Messing J. Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis. Gene. 26:1983;101-106
    • (1983) Gene , vol.26 , pp. 101-106
    • Norrander, J.1    Kempe, T.2    Messing, J.3
  • 22
    • 0036435557 scopus 로고    scopus 로고
    • Site-specific targeting of exogenous DNA into the genome of Candida albicans using the FLP recombinase
    • Sanchez-Martinez C., Perez-Martin J. Site-specific targeting of exogenous DNA into the genome of Candida albicans using the FLP recombinase. Mol. Genet. Genomics. 268:2002;418-424
    • (2002) Mol. Genet. Genomics , vol.268 , pp. 418-424
    • Sanchez-Martinez, C.1    Perez-Martin, J.2
  • 23
    • 0029045375 scopus 로고
    • The CUG codon is decoded in vivo as serine and not leucine in Candida albicans
    • Santos M.A., Tuite M.F. The CUG codon is decoded in vivo as serine and not leucine in Candida albicans. Nucleic Acids Res. 23:1995;1481-1486
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1481-1486
    • Santos, M.A.1    Tuite, M.F.2
  • 24
    • 0037322293 scopus 로고    scopus 로고
    • URA3 as a selectable marker for disruption and virulence assessment of Candida albicans genes
    • Staab J.F., Sundstrom P. URA3 as a selectable marker for disruption and virulence assessment of Candida albicans genes. Trends Microbiol. 11:2003;69-73
    • (2003) Trends Microbiol. , vol.11 , pp. 69-73
    • Staab, J.F.1    Sundstrom, P.2
  • 27
    • 0036015655 scopus 로고    scopus 로고
    • Host versus in vitro signals and intrastrain allelic differences in the expression of a Candida albicans virulence gene
    • Staib P., Kretschmar M., Nichterlein T., Hof H., Morschhäuser J. Host versus in vitro signals and intrastrain allelic differences in the expression of a Candida albicans virulence gene. Mol. Microbiol. 44:2002;1351-1366
    • (2002) Mol. Microbiol. , vol.44 , pp. 1351-1366
    • Staib, P.1    Kretschmar, M.2    Nichterlein, T.3    Hof, H.4    Morschhäuser, J.5
  • 28
    • 0034986998 scopus 로고    scopus 로고
    • Analysis of phase-specific gene expression at the single-cell level in the white-opaque switching system of Candida albicans
    • Strauß A., Michel S., Morschhäuser J. Analysis of phase-specific gene expression at the single-cell level in the white-opaque switching system of Candida albicans. J. Bacteriol. 183:2001;3761-3769
    • (2001) J. Bacteriol. , vol.183 , pp. 3761-3769
    • Strauß, A.1    Michel, S.2    Morschhäuser, J.3
  • 29
    • 0036263539 scopus 로고    scopus 로고
    • Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus
    • Sundstrom P., Cutler J.E., Staab J.F. Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus. Infect. Immun. 70:2002;3281-3283
    • (2002) Infect. Immun. , vol.70 , pp. 3281-3283
    • Sundstrom, P.1    Cutler, J.E.2    Staab, J.F.3
  • 30
    • 0033028595 scopus 로고    scopus 로고
    • Rapid hypothesis testing with Candida albicans through gene disruption with short homology regions
    • Wilson R.B., Davis D., Mitchell A.P. Rapid hypothesis testing with Candida albicans through gene disruption with short homology regions. J. Bacteriol. 181:1999;1868-1874
    • (1999) J. Bacteriol. , vol.181 , pp. 1868-1874
    • Wilson, R.B.1    Davis, D.2    Mitchell, A.P.3
  • 31
    • 0033989179 scopus 로고    scopus 로고
    • Activation of the multiple drug resistance gene MDR1 in fluconazole-resistant, clinical Candida albicans strains is caused by mutations in a trans-regulatory factor
    • Wirsching S., Michel S., Köhler G., Morschhäuser J. Activation of the multiple drug resistance gene MDR1 in fluconazole-resistant, clinical Candida albicans strains is caused by mutations in a trans-regulatory factor. J. Bacteriol. 182:2000;400-404
    • (2000) J. Bacteriol. , vol.182 , pp. 400-404
    • Wirsching, S.1    Michel, S.2    Köhler, G.3    Morschhäuser, J.4
  • 32
    • 0034081664 scopus 로고    scopus 로고
    • Targeted gene disruption in Candida albicans wild-type strains: The role of the MDR1 gene in fluconazole resistance of clinical Candida albicans isolates
    • Wirsching S., Michel S., Morschhäuser J. Targeted gene disruption in Candida albicans wild-type strains: the role of the MDR1 gene in fluconazole resistance of clinical Candida albicans isolates. Mol. Microbiol. 36:2000;856-865
    • (2000) Mol. Microbiol. , vol.36 , pp. 856-865
    • Wirsching, S.1    Michel, S.2    Morschhäuser, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.