Interaction with endothelial cells is a prerequisite for branching ductal-alveolar morphogenesis and hyperplasia of preneoplastic human breast epithelial cells: Regulation by estrogen

Cancer Research

Volumn 60, Issue 2, 2000, Pages 439-449

  Shekhar, Malathy P V ^a,b   Werdell, Jill ^a   Tait, Larry ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KARMANOS CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; CYTOKERATIN; ESTROGEN; INTERLEUKIN 8; MUCIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CELL DIFFERENTIATION; CELL GROWTH; CELL HYPERPLASIA; CONTROLLED STUDY; ENDOTHELIUM CELL; HORMONAL REGULATION; HUMAN; HUMAN CELL; MORPHOGENESIS; PRECANCER; PRIORITY JOURNAL;

BASEMENT MEMBRANE; BREAST; BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; COCULTURE TECHNIQUES; COLLAGEN; CULTURE MEDIA, CONDITIONED; DRUG COMBINATIONS; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; EPITHELIAL CELLS; ESTROGENS; FEMALE; HUMANS; HYPERPLASIA; INTERLEUKIN-8; KERATINS; LAMININ; LYMPHOKINES; MATRIX METALLOPROTEINASE 2; MUCINS; PRECANCEROUS CONDITIONS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEOGLYCANS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0034650561     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (66)

1. Folkman, J., and Cotran, R. Relation of vascular proliferation to tumor growth. Int. Rev. Exp. Pathol., 16: 207-248, 1976.
2. Gimbrone, M. A., Jr., Cotran, R. S., Leapman, S. B., and Folkman, J. Tumor growth and neovascularization: an experimental model using the rabbit cornea. J. Natl. Cancer Inst., 52: 413-427, 1974.
3. Folkman, J. What is the evidence that tumors are angiogenesis dependent? J. Natl. Cancer Inst., 82: 4-6, 1990.
4. Auerbach, R. Angiogenesis-inducing factors: a review. In: E. Pick (ed.), Lymphokines, Vol. 4, pp. 69-84. New York: Academic Press, 1981.
5. Klagsbrun, M., and D'Amore, P. A. Regulation of angiogenesis. Annu. Rev. Physiol., 53: 217-239, 1991.
6. Ferrara, N., and Henzel, W. J. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem. Biophys. Res. Commun., 161: 851-858, 1989.
7. Connolly, D. T., Olander, J. V., Heuvelman, D., Nelson, R., Monsell, R., Siegel, N., Haymore, B. L., Leimgruber, R., and Feder, J. Human vascular permeability factor. Isolation from U937 cells. J. Biol. Chem., 264: 20017-20024, 1989.
8. Leung, D. W., Cachianes, G., Kuang, W. J., Goeddel, D. V., and Ferrara, N. Vascular endothelial growth is a secreted angiogenic mitogen. Science (Washington DC), 246: 1306-1309, 1989.
9. Alon, T., Hemo, I., Itin, A., Pe'er, J., Stone, J., and Kesher, E. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat. Med., 1: 1024-1028, 1995, 1995.
10. Watanabe, Y., and Dvorak, H. F. Vascular permeability factor/vascular endothelial growth factor inhibits anchorage disruption-induced apoptosis in microvessel endothelial cells by inducing scaffold formation. Exp. Cell. Res., 233: 340-349, 1997.
11. Neufeld, G., Cohen, T., Gengrinovitch, S., and Poltorak, Z. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J., 13: 9-22, 1999.
12. Berse, B., Brown, L. F., Van de Water, L., Dvorak, H. F., and Senger, D. R. Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Mol. Biol. Cell, 3: 211-220, 1992.
13. Connolly, D. T., Heuvelman, D. M., Nelson, R., Olander, J. V., Eppley, B. L., Delfino, J. J., Siegel, N. R., Leimgruber, R. M., and Feder, J. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J. Clin. Investig., 84: 1470-1477, 1989.
14. Kim, K. J., Li, B., Winer, J., Armanini, M., Gillett, N., Philips, H., and Ferrara, N. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo. Nature (Lond.), 362: 841-844, 1993.
15. Plate, K. H., Breier, G., Weich, H. A., and Risau, W. Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature (Lond.), 359: 845-848, 1992.
16. Senge, D. R., Galli, S. J., Dvorak, A. M., Perruzzi, C. A., Harvey, V. S., and Dvorak, H. F. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science (Washington DC), 219: 983-985, 1983.
17. Yeo, K. T., Wang, H. H., Nagy, J. A., Sioussat, T. M., Ledbetter, S. R., Hoogewerf, A. J., Zhou, Y., Masse, E. M., Senger, D. R., and Dvorak, H. F. Vascular permeability factor (vascular endothelial growth factor) in guinea pig and human tumor and inflammatory effusions. Cancer Res., 53: 2912-2918, 1983.
18. Cullinan-Bove, K., and Koos, R. Vascular endothelial growth factor/vascular permeability factor expression in the rat uterus: rapid stimulation by estrogen correlates with estrogen-induced increases in uterine capillary permeability and growth. Endocrinology, 133: 829-837, 1993.
19. Nakamura, J., Savinov, A., Lu, Q., and Brodie, A. Estrogen regulates vascular endothelial growth/permeability factor expression in 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors. Endocrinology, 137: 5589-5596, 1996.
20. Shekhar, P. V. M., Nangia-Makker, P., Wolman, S., Tait, L., Heppner, G. H., and Visscher, D. W. Direct action of estrogen on sequence of progression of human preneoplastic breast disease. Am. J. Pathol., 152: 1129-1132, 1998.
21. Polverini, P. J. How the extracellular matrix and macrophages contribute to angiogenesis-dependent diseases. Eur. J. Cancer, 32A: 2430-2437, 1996.
22. Barcellos-Hoff, M. H., Aggeler, J., Ram, T. G., and Bissell, M. J. Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. Development (Camb.), 105: 223-235, 1989.
23. Boudreau, N., Sympson, C. J., Werb, Z., and Bissell, M. J. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science (Washington DC), 267: 891-893, 1995.
24. Liotta, L. A., Steeg, P. S., and Stetler-Stevenson, W. G. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell, 64: 327-336, 1991.
25. Liotta, L. A., Tryggvason, K., Garbisa, S., Hart, I., Foltz, C. M., and Shafie, S. Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature (Lond.), 284: 67-68, 1980.
26. Liotta, L. A., Tryggvason, K., Garbisa, S., Robey, P. G., and Abe, S. Partial purification and characterization of a neutral protease which cleaves type IV collagen. Biochemistry, 20: 100-104, 1981.
27. Wilhelm, S. M., Collier, I. E., Marmer, B. L., Eisen, A. Z., Grant, G. A., and Goldberg, G. I. SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. J. Biol. Chem., 264: 17213-17221, 1989.
28. Stetler-Stevenson, W. G., Krutzsch, H. C., Wacher, M. P., Margulies, I. M., and Liotta, L. A. The activation of human type IV collagenase proenzyme. Sequence identification of the major conversion product following organomercurial activation. J. Biol. Chem., 264: 1353-1356, 1989.
29. Collier, I. E., Wilhelm, S. M., Eisen, A. Z., Marmer, B. L., Grant, G. A., Seltzer, J. L., Kronberger, A., He, C. S., Bauer, E. A., and Goldberg, G. I. H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen. J. Biol. Chem., 263: 6579-6587, 1988.
30. Miller, F. R., Soule, H. D., Tait, L., Pauley, R. J., Wolman, S. R., Dawson, P. J., and Heppner, G. H. Xenograft model of human proliferative breast disease. J. Natl. Cancer Inst., 85: 1725-1732, 1993.
31. Basolo, F., Elliot, J., Tait, L., Chen, X. Q., Maloney, T., Russo, I. H., Pauley, R., Momiki, S., Caamano, J., Klein-Szanto, A. J., and Russo, J. Transformation of human breast epithelial cells by c-Ha-ras oncogene. Mol. Carcinog., 4: 25-35, 1991.
32. Dawson, P. J., Wolman, S. R., Tait, L., Heppner, G. H., and Miller, F. R. MCF10AT: a model for the evolution of cancer from proliferative breast disease. Am. J. Pathol., 148: 313-319, 1996.
33. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
34. Ishibashi, M., Ito, A., Sakyo, K., and Mori, Y. Procollagenase activator produced by rabbit uterine cervical fibroblasts. Biochem. J., 241: 527-534, 1987.
35. Polverini, P. J. The pathophysiology of angiogenesis. Crit. Rev. Oral Biol. Med., 6: 230-247, 1995.
36. Bar-Eli, M. Role of interleukin-8 in tumor growth and metastasis of human melanoma. Pathobiology, 67: 12-18, 1999.
37. Kumar, R., Yoneda, J., Bucana, C. D., and Fidler, I. J. 1998. Regulation of distinct steps of angiogenesis by different angiogenic molecules. Int. J. Oncol., 12: 749-757, 1998.
38. Miller, L. J., Kurtzman, S. H., Wang, Y., Anderson, K. H., Lindquist, R. R., and Kreutzer, D. L. Expression of interleukin-8 receptors on tumor cells and vascular endothelial cells in human breast cancer tissue. Anticancer Res., 18: 77-81, 1998.
39. Kufe, D., Inghirami, G., Abe, M., Hayes, D., Justi-Wheeler, H., and Schlom, J. Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma, 3: 223-232, 1984.
40. Kim-Schulze, S., McGowan, K. A., Hubchak, S. C., Cid, M. C., Martin, M. B., Kleinman, H. K., Greene, G. L., and Schnaper, H. W. Expression of an estrogen receptor by human coronary artery and umbilical vein endothelial cells. Circulation, 94: 1402-1407, 1996.
41. Soule, H. D., Maloney, T. M., Wolman, S. R., Peterson, W. D., Brenz, R., McGrath, C. M., Russo, J., Pauley, R. J., Jones, R. F., and Brooks, S. C. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res., 50: 6075-6086, 1990.
42. Murphy, L. C., Dotzlaw, H., Leygue, E., Douglas, D., Coutts, A., and Watson, P. H. Estrogen receptor variants and mutations. J. Steroid Biochem. Mol. Biol., 62: 363-372, 1997.
43. Moses, M. A., Sudhalter, J., and Langer, R. Identification of an inhibitor of neovascularization from cartilage. Science (Washington DC), 248: 1408-1410, 1990.
44. Mignatti, P., Tusboi, R., Robbins, E., and Rifkin, D. B. In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases. J. Cell Biol., 108: 671-682, 1988.
45. Johnson, M. D., Kim, H-R. C., Chesler, L., Tsao-Wu, G., Bouck, N., and Polverini, P. J. Inhibition of angiogenesis by tissue inhibitor of metalloproteinase. J. Cell Physiol., 160: 194-202, 1994.
46. Ingher, D. E. Extracellular matrix as a solid-state regulator of angiogenesis: identification of new targets for anti-cancer therapy. Cancer Biol., 3: 57-63, 1992.
47. Gabrisa, S., Pozzatti, R., Muschel, R. J., Saffiotti, U., Ballian, M., Goldfarb, R. H., Khoury, G., and Liotta, L. A. Secretion of type IV collagenolytic protease and metastatic phenotype induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-Ela. Cancer Res., 47: 1523-1528, 1987.
48. Liotta, L. A., and Stetler-Stevenson, W. G. Metalloproteinases and malignant conversion: does correlation imply causality? J. Natl. Cancer Inst., 81: 556-557, 1989.
49. r 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells. Cancer Res., 50: 3872-3877, 1990.
50. Okada, Y., Tsuchiya, H., Shimizu, H., Tomita, K., Nakanishi, I., Sata, H., Seiki, M., Yamashita, K., and Hayakawa, T. Induction and stimulation of 92 kDa gelatinase type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor α. Biochem. Biophys. Res. Commun., 171: 610-617, 1990.
51. Schnaper, H. W., Grant, D. S., Stetler-Stevenson, W. G., Fridman, R., D'Orazi, G., Murphy, A. N., Bird, R. E., Hoythya, M., Fuerst, T. R., French, D. L., Quigley, J. P., and Kleinman, H. K. Type IV collagenase(s) and TIMPs modulate endothelial cell morphologies in vitro. J. Cell Physiol., 166: 235-246, 1993.
52. Rak, J., Filmus, J., and Kerbel, R. S. Reciprocal paracrine interactions between tumor cells and endothelial cells: the "angiogenesis progression" hypothesis. Eur. J. Cancer, 32A: 2438-2450, 1996.
53. Bouck, N. Tumor angiogenesis: role of oncogenes and tumor suppressor genes. Cancer Cells, 2: 179-185, 1990.
54. Bouck, N. Angiogenesis: a mechanism by which oncogenes and tumor suppressor genes regulate tumorigenesis. In: C. C. Benz and E. T. Liu (eds.), Oncogenes and Tumor Suppressor Genes in Human Malignancy, pp. 359-371. Boston: Kluwer Academic, 1993.
55. Shekhar, P. V. M., Werdell, J., and Basrur, V. S. Environmental estrogen stimulation of growth and estrogen receptor function in preneoplastic and cancerous human breast cells. J. Natl. Cancer Inst., 89: 1774-1782, 1997.
56. Shekhar, P. V. M., Chen, M. L., Werdell, J., Heppner, G. H., Miller, F. R., and Christman, J. K. Activation of expression of functional endogenous estrogen receptor in MCF10AT xenografts, a model for early human breast cancer. Int. J. Oncol., 13: 907-915, 1998.
57. Pilat, M. J., Christman, J. K., and Brooks, S. C. Characterization of the estrogen receptor transfected MCF10A breast cell line 139B6. Breast Cancer Res. Treat., 37: 253-266, 1996.
58. Johannisson, E. Effects of oestradiol and progesterone on the synthesis of DNA and the anti-hemophilic factor VIII antigen in human endometrial endothelial cells in vitro: a pilot study. Hum. Reprod., 1: 207-212, 1986.
59. Kaidoh, T., Yasugi, T., and Uehara, Y. The microvasculature of the 7,12-dimethylbenz(a)anthracene (DMBA)-induced rat mammary tumor 1 vascular patterns as visualized by scanning electron microscopy of corrosion casts. Virchows Arch. A. Pathol. Anal. Histopathol., 418: 111-117, 1991.
60. 3H-thymidine autoradiography. Basic Appl. Histochem., 29: 21-43, 1985.
61. Banerjee, S. K., Sarkar, D. K., Weston, A. P., De, A., and Campbell, D. R. Over expression of vascular endothelial growth factor and its receptor during the development of estrogen-induced rat pituitary tumors may mediate estrogen-initiated tumor angiogenesis. Carcinogenesis (Lond.), 18: 1155-1161, 1997.
62. Dowsett, M., Daffada, A., Chan, C. M., and Johnston, S. R. Oestrogen receptor mutants and variants in breast cancer. Eur. J. Cancer, 33: 1177-1183, 1997.
63. Tonetti, D. A., and Jordan, V. C. The role of estrogen receptor mutations in tamoxifen-stimulated breast cancer. J. Steroid Biochem. Mol. Biol., 62: 119-128, 1997.
64. Folkman, J. Tumor angiogenesis. Adv. Cancer Res., 43: 175-203, 1985.
65. Vlodavsky, I., Fuks, Z., Ishai-Michaeli, R., Bashkin, P., Levi, E., Korner, G., Bar-Shavit, R., and Klagsbrun, M. Extracellular matrix-resident basic fibroblast growth factor: implications for control of angiogenesis. J. Cell Biochem., 47: 167-176, 1991.
66. Vlodavsky, I., Bar-Shavit, R., Ishai-Michaeli, R., Bashkin, P., and Fuks, Z. Extracellular sequestration and release of fibroblast growth factor: a regulatory mechanism? Trends Biochem. Sci., 16: 268-271, 1991.