Impact of the 3D Microenvironment on Phenotype, Gene Expression, and EGFR Inhibition of Colorectal Cancer Cell Lines

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Luca, Anna C ^a   Mersch, Sabrina ^a   Deenen, René ^b   Schmidt, Stephan ^a   Messner, Isabelle ^a   Schäfer, Karl Ludwig ^a   Baldus, Stephan E ^a   Huckenbeck, Wolfgang ^a   Piekorz, Roland P ^a   Knoefel, Wolfram T ^a   Krieg, Andreas ^a   Stoecklein, Nikolas H ^a  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL INVASION; CELL LINE; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL STRAIN COLO 205; CELL STRAIN COLO 206F; CELL STRAIN DLD 1; CELL STRAIN HT29; CELL STRAIN LOVO; CELL STRAIN SW 480; CELL STRUCTURE; CELL TYPE; CLINICAL ARTICLE; COLORECTAL CANCER; CONFOCAL LASER SCANNING FLUORESCENCE MICROSCOPY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HUMAN; HUMAN CELL; LAMININ RICH EXTRACELLULAR MATRIX; MALE; ONCOGENE K RAS; PHASE CONTRAST MICROSCOPY; SIGNAL TRANSDUCTION; SOLID TUMOR; STRUCTURE ANALYSIS; THREE DIMENSIONAL CANCER CELL CULTURE; TUMOR MICROENVIRONMENT; TWO DIMENSIONAL CANCER CELL CULTURE; WILD TYPE;

CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LAMININ; PHENOTYPE; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SPHEROIDS, CELLULAR; TUMOR MICROENVIRONMENT;

VITACEAE;

EID: 84875444552     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059689     Document Type: Article

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