-
1
-
-
0037228105
-
Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey
-
Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS: Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis 41: 1-12, 2003
-
(2003)
Am J Kidney Dis
, vol.41
, pp. 1-12
-
-
Coresh, J.1
Astor, B.C.2
Greene, T.3
Eknoyan, G.4
Levey, A.S.5
-
2
-
-
33748301941
-
Chronic kidney disease: A European perspective
-
Lameire N, Jager K, Van Biesen W, de Bacquer D, Vanholder R: Chronic kidney disease: A European perspective. Kidney Int Suppl 68: S30-S38, 2005
-
(2005)
Kidney Int Suppl
, vol.68
, pp. S30-S38
-
-
Lameire, N.1
Jager, K.2
Van Biesen, W.3
De Bacquer, D.4
Vanholder, R.5
-
3
-
-
0025053161
-
Distribution of type I collagen in human kidney diseases in comparison with type III collagen
-
Yoshioka K, Tohda M, Takemura T, Akano N, Matsubara K, Ooshima A, Maki S: Distribution of type I collagen in human kidney diseases in comparison with type III collagen. J Pathol 162: 141-148, 1990
-
(1990)
J Pathol
, vol.162
, pp. 141-148
-
-
Yoshioka, K.1
Tohda, M.2
Takemura, T.3
Akano, N.4
Matsubara, K.5
Ooshima, A.6
Maki, S.7
-
4
-
-
0034991582
-
Stimulation of pro-alpha(1)(I) collagen by TGF-beta(1) in mesangial cells: Role of the p38 MAPK pathway
-
Chin BY, Mohsenin A, Li SX, Choi AM, Choi ME: Stimulation of pro-alpha(1)(I) collagen by TGF-beta(1) in mesangial cells: Role of the p38 MAPK pathway. Am J Physiol Renal Physiol 280: F495-F504, 2001
-
(2001)
Am J Physiol Renal Physiol
, vol.280
, pp. F495-F504
-
-
Chin, B.Y.1
Mohsenin, A.2
Li, S.X.3
Choi, A.M.4
Choi, M.E.5
-
5
-
-
84857111725
-
The origin of interstitial myofibroblasts in chronic kidney disease
-
Grgic I, Duffield JS, Humphreys BD: The origin of interstitial myofibroblasts in chronic kidney disease. Pediatr Nephrol 27: 183-193, 2012
-
(2012)
Pediatr Nephrol
, vol.27
, pp. 183-193
-
-
Grgic, I.1
Duffield, J.S.2
Humphreys, B.D.3
-
6
-
-
77950565076
-
Autophagy is a component of epithelial cell fate in obstructive uropathy
-
Li L, Zepeda-Orozco D, Black R, Lin F: Autophagy is a component of epithelial cell fate in obstructive uropathy. Am J Pathol 176: 1767-1778, 2010
-
(2010)
Am J Pathol
, vol.176
, pp. 1767-1778
-
-
Li, L.1
Zepeda-Orozco, D.2
Black, R.3
Lin, F.4
-
7
-
-
77957252460
-
Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells
-
Koesters R, Kaissling B, Lehir M, Picard N, Theilig F, Gebhardt R, Glick AB, Hähnel B, Hosser H, Gröne HJ, Kriz W: Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am J Pathol 177: 632-643, 2010
-
(2010)
Am J Pathol
, vol.177
, pp. 632-643
-
-
Koesters, R.1
Kaissling, B.2
Lehir, M.3
Picard, N.4
Theilig, F.5
Gebhardt, R.6
Glick, A.B.7
Hähnel, B.8
Hosser, H.9
Gröne, H.J.10
Kriz, W.11
-
8
-
-
0346727324
-
Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulo-interstitial fibrosis induced by unilateral ureteral obstruction
-
Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A: Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulo-interstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112: 1486-1494, 2003
-
(2003)
J Clin Invest
, vol.112
, pp. 1486-1494
-
-
Sato, M.1
Muragaki, Y.2
Saika, S.3
Roberts, A.B.4
Ooshima, A.5
-
9
-
-
0033848986
-
Matrix metalloproteinases: Effectors of development and normal physiology
-
Vu TH, Werb Z: Matrix metalloproteinases: Effectors of development and normal physiology. Genes Dev 14: 2123-2133, 2000
-
(2000)
Genes Dev
, vol.14
, pp. 2123-2133
-
-
Vu, T.H.1
Werb, Z.2
-
10
-
-
0033618337
-
Matrix metalloproteinases
-
Nagase H, Woessner JF Jr.: Matrix metalloproteinases. J Biol Chem 274: 21491-21494, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 21491-21494
-
-
Nagase, H.1
Woessner, J.F.2
-
11
-
-
0023025366
-
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix
-
Ignotz RA, Massagué J: Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 261: 4337-4345, 1986
-
(1986)
J Biol Chem
, vol.261
, pp. 4337-4345
-
-
Ignotz, R.A.1
Massagué, J.2
-
12
-
-
0037439630
-
Making sense of latent TGFbeta activation
-
Annes JP, Munger JS, Rifkin DB: Making sense of latent TGFbeta activation. J Cell Sci 116: 217-224, 2003
-
(2003)
J Cell Sci
, vol.116
, pp. 217-224
-
-
Annes, J.P.1
Munger, J.S.2
Rifkin, D.B.3
-
13
-
-
0028906190
-
Processing of transforming growth factor beta 1 precursor by human furin convertase
-
Dubois CM, Laprise MH, Blanchette F, Gentry LE, Leduc R: Processing of transforming growth factor beta 1 precursor by human furin convertase. J Biol Chem 270: 10618-10624, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 10618-10624
-
-
Dubois, C.M.1
Laprise, M.H.2
Blanchette, F.3
Gentry, L.E.4
Leduc, R.5
-
14
-
-
34848886914
-
Autophagosome formation: Core machinery and adaptations
-
Xie Z, Klionsky DJ: Autophagosome formation: Core machinery and adaptations. Nat Cell Biol 9: 1102-1109, 2007
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1102-1109
-
-
Xie, Z.1
Klionsky, D.J.2
-
15
-
-
77957657436
-
Induction of autophagic flux by amino acid deprivation is distinct from nitrogen starvation-induced macroautophagy
-
Ecker N, Mor A, Journo D, Abeliovich H: Induction of autophagic flux by amino acid deprivation is distinct from nitrogen starvation-induced macroautophagy. Autophagy 6: 879-890, 2010
-
(2010)
Autophagy
, vol.6
, pp. 879-890
-
-
Ecker, N.1
Mor, A.2
Journo, D.3
Abeliovich, H.4
-
16
-
-
33947250696
-
The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis
-
Liang J, Shao SH, Xu ZX, Hennessy B, Ding Z, Larrea M, Kondo S, Dumont DJ, Gutterman JU, Walker CL, Slingerland JM, Mills GB: The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis. Nat Cell Biol 9: 218-224, 2007
-
(2007)
Nat Cell Biol
, vol.9
, pp. 218-224
-
-
Liang, J.1
Shao, S.H.2
Xu, Z.X.3
Hennessy, B.4
Ding, Z.5
Larrea, M.6
Kondo, S.7
Dumont, D.J.8
Gutterman, J.U.9
Walker, C.L.10
Slingerland, J.M.11
Mills, G.B.12
-
17
-
-
79952797948
-
Autophagy: Regulation by energy sensing
-
Meijer AJ, Codogno P: Autophagy: Regulation by energy sensing. Curr Biol 21: R227-R229, 2011
-
(2011)
Curr Biol
, vol.21
, pp. R227-R229
-
-
Meijer, A.J.1
Codogno, P.2
-
18
-
-
79955804227
-
Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: Implications for Alzheimer's disease
-
Nijholt DA, de Graaf TR, van Haastert ES, Oliveira AO, Berkers CR, Zwart R, Ovaa H, Baas F, Hoozemans JJ, Scheper W: Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: Implications for Alzheimer's disease. Cell Death Differ 18: 1071-1081, 2011
-
(2011)
Cell Death Differ
, vol.18
, pp. 1071-1081
-
-
Nijholt, D.A.1
De Graaf, T.R.2
Van Haastert, E.S.3
Oliveira, A.O.4
Berkers, C.R.5
Zwart, R.6
Ovaa, H.7
Baas, F.8
Hoozemans, J.J.9
Scheper, W.10
-
19
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
Majmundar AJ, Wong WJ, Simon MC: Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell 40: 294-309, 2010
-
(2010)
Mol Cell
, vol.40
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
20
-
-
34247186472
-
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
-
Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z: Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J 26: 1749-1760, 2007
-
(2007)
EMBO J
, vol.26
, pp. 1749-1760
-
-
Scherz-Shouval, R.1
Shvets, E.2
Fass, E.3
Shorer, H.4
Gil, L.5
Elazar, Z.6
-
21
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G: Autophagy in the pathogenesis of disease. Cell 132: 27-42, 2008
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
22
-
-
72949111893
-
Physiological functions of autophagy
-
Mizushima N: Physiological functions of autophagy. Curr Top Microbiol Immunol 335: 71-84, 2009
-
(2009)
Curr Top Microbiol Immunol
, vol.335
, pp. 71-84
-
-
Mizushima, N.1
-
23
-
-
0035503594
-
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
-
Suzuki K, Kirisako T, Kamada Y, Mizushima N, Noda T, Ohsumi Y: The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J 20: 5971-5981, 2001
-
(2001)
EMBO J
, vol.20
, pp. 5971-5981
-
-
Suzuki, K.1
Kirisako, T.2
Kamada, Y.3
Mizushima, N.4
Noda, T.5
Ohsumi, Y.6
-
24
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N: Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A 100: 15077-15082, 2003
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
25
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X, Yu J, Bhagat G, Furuya N, Hibshoosh H, Troxel A, Rosen J, Eskelinen EL, Mizushima N, Ohsumi Y, Cattoretti G, Levine B: Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 112: 1809-1820, 2003
-
(2003)
J Clin Invest
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
Troxel, A.6
Rosen, J.7
Eskelinen, E.L.8
Mizushima, N.9
Ohsumi, Y.10
Cattoretti, G.11
Levine, B.12
-
26
-
-
49949098271
-
BAC-mediated transgenic expression of fluorescent autophagic protein Beclin 1 reveals a role for Beclin 1 in lymphocyte development
-
Arsov I, Li X, Matthews G, Coradin J, Hartmann B, Simon AK, Sealfon SC, Yue Z: BAC-mediated transgenic expression of fluorescent autophagic protein Beclin 1 reveals a role for Beclin 1 in lymphocyte development. Cell Death Differ 15: 1385-1395, 2008
-
(2008)
Cell Death Differ
, vol.15
, pp. 1385-1395
-
-
Arsov, I.1
Li, X.2
Matthews, G.3
Coradin, J.4
Hartmann, B.5
Simon, A.K.6
Sealfon, S.C.7
Yue, Z.8
-
27
-
-
45749114895
-
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice
-
Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, Wyss-Coray T: The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J Clin Invest 118: 2190-2199, 2008
-
(2008)
J Clin Invest
, vol.118
, pp. 2190-2199
-
-
Pickford, F.1
Masliah, E.2
Britschgi, M.3
Lucin, K.4
Narasimhan, R.5
Jaeger, P.A.6
Small, S.7
Spencer, B.8
Rockenstein, E.9
Levine, B.10
Wyss-Coray, T.11
-
28
-
-
84859509946
-
Autophagy promotes intracellular degradation of type I collagen induced by transforming growth factor (TGF)-β1
-
Kim SI, Na HJ, Ding Y, Wang Z, Lee SJ, Choi ME: Autophagy promotes intracellular degradation of type I collagen induced by transforming growth factor (TGF)-β1. J Biol Chem 287: 11677-11688, 2012
-
(2012)
J Biol Chem
, vol.287
, pp. 11677-11688
-
-
Kim, S.I.1
Na, H.J.2
Ding, Y.3
Wang, Z.4
Lee, S.J.5
Choi, M.E.6
-
29
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y, Yoshimori T: LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19: 5720-5728, 2000
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
30
-
-
77951169411
-
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
-
Hartleben B, Gödel M, Meyer-Schwesinger C, Liu S, Ulrich T, Köbler S, Wiech T, Grahammer F, Arnold SJ, Lindenmeyer MT, Cohen CD, Pavenstädt H, Kerjaschki D, Mizushima N, Shaw AS, Walz G, Huber TB: Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest 120: 1084-1096, 2010
-
(2010)
J Clin Invest
, vol.120
, pp. 1084-1096
-
-
Hartleben, B.1
Gödel, M.2
Meyer-Schwesinger, C.3
Liu, S.4
Ulrich, T.5
Köbler, S.6
Wiech, T.7
Grahammer, F.8
Arnold, S.J.9
Lindenmeyer, M.T.10
Cohen, C.D.11
Pavenstädt, H.12
Kerjaschki, D.13
Mizushima, N.14
Shaw, A.S.15
Walz, G.16
Huber, T.B.17
-
31
-
-
79952628267
-
The Beclin 1 network regulates autophagy and apoptosis
-
Kang R, Zeh HJ, Lotze MT, Tang D: The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 18: 571-580, 2011
-
(2011)
Cell Death Differ
, vol.18
, pp. 571-580
-
-
Kang, R.1
Zeh, H.J.2
Lotze, M.T.3
Tang, D.4
-
32
-
-
33646532461
-
Pathogenesis of renal injury in obstructive uropathy
-
Chevalier RL: Pathogenesis of renal injury in obstructive uropathy. Curr Opin Pediatr 18: 153-160, 2006
-
(2006)
Curr Opin Pediatr
, vol.18
, pp. 153-160
-
-
Chevalier, R.L.1
-
33
-
-
79957886201
-
Characterization of macroautophagic flux in vivo using a leupeptin-based assay
-
Haspel J, Shaik RS, Ifedigbo E, Nakahira K, Dolinay T, Englert JA, Choi AM: Characterization of macroautophagic flux in vivo using a leupeptin-based assay. Autophagy 7: 629-642, 2011
-
(2011)
Autophagy
, vol.7
, pp. 629-642
-
-
Haspel, J.1
Shaik, R.S.2
Ifedigbo, E.3
Nakahira, K.4
Dolinay, T.5
Englert, J.A.6
Choi, A.M.7
-
34
-
-
0025765844
-
A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1
-
Miyazono K, Olofsson A, Colosetti P, Heldin CH: A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1. EMBO J 10: 1091-1101, 1991
-
(1991)
EMBO J
, vol.10
, pp. 1091-1101
-
-
Miyazono, K.1
Olofsson, A.2
Colosetti, P.3
Heldin, C.H.4
-
35
-
-
77957669416
-
The Golgi as a potential membrane source for autophagy
-
Geng J, Klionsky DJ: The Golgi as a potential membrane source for autophagy. Autophagy 6: 950-951, 2010
-
(2010)
Autophagy
, vol.6
, pp. 950-951
-
-
Geng, J.1
Klionsky, D.J.2
-
36
-
-
75749122303
-
Methods in mammalian autophagy research
-
Mizushima N, Yoshimori T, Levine B: Methods in mammalian autophagy research. Cell 140: 313-326, 2010
-
(2010)
Cell
, vol.140
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
37
-
-
66149130696
-
Tgf-beta auto-induction and connective tissue growth factor expression in human renal tubule epithelial cells requires N-ras
-
Dockrell ME, Phanish MK, Hendry BM: Tgf-beta auto-induction and connective tissue growth factor expression in human renal tubule epithelial cells requires N-ras. Nephron, Exp Nephrol 112: e71-e79, 2009
-
(2009)
Nephron, Exp Nephrol
, vol.112
, pp. e71-e79
-
-
Dockrell, M.E.1
Phanish, M.K.2
Hendry, B.M.3
-
38
-
-
0027424626
-
Rat mesangial cell hypertrophy in response to transforming growth factor-beta 1
-
Choi ME, Kim EG, Huang Q, Ballermann BJ: Rat mesangial cell hypertrophy in response to transforming growth factor-beta 1. Kidney Int 44: 948-958, 1993
-
(1993)
Kidney Int
, vol.44
, pp. 948-958
-
-
Choi, M.E.1
Kim, E.G.2
Huang, Q.3
Ballermann, B.J.4
-
39
-
-
0031593675
-
Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells
-
Yamamoto A, Tagawa Y, Yoshimori T, Moriyama Y, Masaki R, Tashiro Y: Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells. Cell Struct Funct 23: 33-42, 1998
-
(1998)
Cell Struct Funct
, vol.23
, pp. 33-42
-
-
Yamamoto, A.1
Tagawa, Y.2
Yoshimori, T.3
Moriyama, Y.4
Masaki, R.5
Tashiro, Y.6
-
40
-
-
53549084325
-
Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?
-
Klionsky DJ, Elazar Z, Seglen PO, Rubinsztein DC: Does bafilomycin A1 block the fusion of autophagosomes with lysosomes? Autophagy 4: 849-850, 2008
-
(2008)
Autophagy
, vol.4
, pp. 849-850
-
-
Klionsky, D.J.1
Elazar, Z.2
Seglen, P.O.3
Rubinsztein, D.C.4
-
41
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ: Autophagy fights disease through cellular self-digestion. Nature 451: 1069-1075, 2008
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
42
-
-
84877609568
-
Autophagy in human health and disease
-
Choi AM, Ryter SW, Levine B: Autophagy in human health and disease. N Engl J Med 368: 1845-1846, 2013
-
(2013)
N Engl J Med
, vol.368
, pp. 1845-1846
-
-
Choi, A.M.1
Ryter, S.W.2
Levine, B.3
-
43
-
-
84871037851
-
Fibroblast autophagy in fibrotic disorders
-
Del Principe D, Lista P, Malorni W, Giammarioli AM: Fibroblast autophagy in fibrotic disorders. J Pathol 229: 208-220, 2013
-
(2013)
J Pathol
, vol.229
, pp. 208-220
-
-
Del Principe, D.1
Lista, P.2
Malorni, W.3
Giammarioli, A.M.4
-
44
-
-
84862952042
-
The role of autophagy in unilateral ureteral obstruction rat model
-
Kim WY, Nam SA, Song HC, Ko JS, Park SH, Kim HL, Choi EJ, Kim YS, Kim J, Kim YK: The role of autophagy in unilateral ureteral obstruction rat model. Nephrology (Carlton) 17: 148-159, 2012
-
(2012)
Nephrology (Carlton)
, vol.17
, pp. 148-159
-
-
Kim, W.Y.1
Nam, S.A.2
Song, H.C.3
Ko, J.S.4
Park, S.H.5
Kim, H.L.6
Choi, E.J.7
Kim, Y.S.8
Kim, J.9
Kim, Y.K.10
-
45
-
-
77950252174
-
Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1
-
Djavaheri-Mergny M, Maiuri MC, Kroemer G: Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1. Oncogene 29: 1717-1719, 2010
-
(2010)
Oncogene
, vol.29
, pp. 1717-1719
-
-
Djavaheri-Mergny, M.1
Maiuri, M.C.2
Kroemer, G.3
-
46
-
-
33847350691
-
Common and uniquemechanisms regulate fibrosis in various fibroproliferative diseases
-
Wynn TA: Common and uniquemechanisms regulate fibrosis in various fibroproliferative diseases. J Clin Invest 117: 524-529, 2007
-
(2007)
J Clin Invest
, vol.117
, pp. 524-529
-
-
Wynn, T.A.1
-
47
-
-
0036322007
-
Evidence that fibroblasts derive from epithelium during tissue fibrosis
-
Iwano M, Plieth D, Danoff TM, Xue C, Okada H, Neilson EG: Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 110: 341-350, 2002
-
(2002)
J Clin Invest
, vol.110
, pp. 341-350
-
-
Iwano, M.1
Plieth, D.2
Danoff, T.M.3
Xue, C.4
Okada, H.5
Neilson, E.G.6
-
48
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
Kalluri R, Neilson EG: Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112: 1776-1784, 2003
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
49
-
-
34250733867
-
The role of tubular epithelial-mesenchymal transition in progressive kidney disease
-
Burns WC, Kantharidis P, Thomas MC: The role of tubular epithelial-mesenchymal transition in progressive kidney disease. Cells Tissues Organs 185: 222-231, 2007
-
(2007)
Cells Tissues Organs
, vol.185
, pp. 222-231
-
-
Burns, W.C.1
Kantharidis, P.2
Thomas, M.C.3
-
50
-
-
78149298226
-
Mechanisms of tubulointerstitial fibrosis
-
Zeisberg M, Neilson EG: Mechanisms of tubulointerstitial fibrosis. J Am Soc Nephrol 21: 1819-1834, 2010
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1819-1834
-
-
Zeisberg, M.1
Neilson, E.G.2
-
51
-
-
84866516950
-
Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGFB and CTGF through LPA2- and Gaq-mediated Rho and avb6 integrindependent activation of TGF-b
-
Geng H, Lan R, Singha PK, Gilchrist A, Weinreb PH, Violette SM, Weinberg JM, Saikumar P, Venkatachalam MA: Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGFB and CTGF through LPA2- and Gaq-mediated Rho and avb6 integrindependent activation of TGF-b. Am J Pathol 181: 1236-1249, 2012
-
(2012)
Am J Pathol
, vol.181
, pp. 1236-1249
-
-
Geng, H.1
Lan, R.2
Singha, P.K.3
Gilchrist, A.4
Weinreb, P.H.5
Violette, S.M.6
Weinberg, J.M.7
Saikumar, P.8
Venkatachalam, M.A.9
-
52
-
-
79953176280
-
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
-
Harris J, Hartman M, Roche C, Zeng SG, O'Shea A, Sharp FA, Lambe EM, Creagh EM, Golenbock DT, Tschopp J, Kornfeld H, Fitzgerald KA, Lavelle EC: Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation. J Biol Chem 286: 9587-9597, 2011
-
(2011)
J Biol Chem
, vol.286
, pp. 9587-9597
-
-
Harris, J.1
Hartman, M.2
Roche, C.3
Zeng, S.G.4
O'Shea, A.5
Sharp, F.A.6
Lambe, E.M.7
Creagh, E.M.8
Golenbock, D.T.9
Tschopp, J.10
Kornfeld, H.11
Fitzgerald, K.A.12
Lavelle, E.C.13
-
53
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1 b production by targeting ubiquitinated inflammasomes for destruction
-
Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, Sher A, Kehrl JH: Activation of autophagy by inflammatory signals limits IL-1 b production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol 13: 255-263, 2012
-
(2012)
Nat Immunol
, vol.13
, pp. 255-263
-
-
Shi, C.S.1
Shenderov, K.2
Huang, N.N.3
Kabat, J.4
Abu-Asab, M.5
Fitzgerald, K.A.6
Sher, A.7
Kehrl, J.H.8
-
54
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S: Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 456: 264-268, 2008
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.G.5
Satoh, T.6
Omori, H.7
Noda, T.8
Yamamoto, N.9
Komatsu, M.10
Tanaka, K.11
Kawai, T.12
Tsujimura, T.13
Takeuchi, O.14
Yoshimori, T.15
Akira, S.16
-
55
-
-
79954459822
-
Inflammasome-independent modulation of cytokine response by autophagy in human cells
-
Crişan TO, Plantinga TS, van de Veerdonk FL, Farcasx MF, Stoffels M, Kullberg BJ, van der Meer JW, Joosten LA, Netea MG: Inflammasome-independent modulation of cytokine response by autophagy in human cells. PLoS ONE 6: e18666, 2011
-
(2011)
PLoS ONE
, vol.6
, pp. e18666
-
-
Crişan, T.O.1
Plantinga, T.S.2
Van De Veerdonk, F.L.3
Farcasx, M.F.4
Stoffels, M.5
Kullberg, B.J.6
Van Der Meer, J.W.7
Joosten, L.A.8
Netea, M.G.9
-
56
-
-
77950362382
-
The inflammasomes
-
Schroder K, Tschopp J: The inflammasomes. Cell 140: 821-832, 2010
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
57
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, Englert JA, Rabinovitch M, Cernadas M, Kim HP, Fitzgerald KA, Ryter SW, Choi AM: Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 12: 222-230, 2011
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
Rabinovitch, M.8
Cernadas, M.9
Kim, H.P.10
Fitzgerald, K.A.11
Ryter, S.W.12
Choi, A.M.13
-
58
-
-
20144378863
-
Transient myofibroblast differentiation of interstitial fibroblastic cells relevant to tubular dilatation in uranyl acetate-induced acuterenal failure inrats
-
Fujigaki Y, Muranaka Y, Sun D, Goto T, Zhou H, Sakakima M, Fukasawa H, Yonemura K, Yamamoto T, Hishida A: Transient myofibroblast differentiation of interstitial fibroblastic cells relevant to tubular dilatation in uranyl acetate-induced acuterenal failure inrats. Virchows Arch 446: 164-176, 2005
-
(2005)
Virchows Arch
, vol.446
, pp. 164-176
-
-
Fujigaki, Y.1
Muranaka, Y.2
Sun, D.3
Goto, T.4
Zhou, H.5
Sakakima, M.6
Fukasawa, H.7
Yonemura, K.8
Yamamoto, T.9
Hishida, A.10
-
59
-
-
0035144846
-
Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat
-
Suzuki T, Kimura M, Asano M, Fujigaki Y, Hishida A: Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat. Am J Pathol 158: 75-85, 2001
-
(2001)
Am J Pathol
, vol.158
, pp. 75-85
-
-
Suzuki, T.1
Kimura, M.2
Asano, M.3
Fujigaki, Y.4
Hishida, A.5
-
60
-
-
38149098485
-
Developmental expression of LC3alpha and beta: Absence of fibronectin or autophagy phenotype in LC3beta knockout mice
-
Cann GM, Guignabert C, Ying L, Deshpande N, Bekker JM, Wang L, Zhou B, Rabinovitch M: Developmental expression of LC3alpha and beta: Absence of fibronectin or autophagy phenotype in LC3beta knockout mice. Dev Dyn 237: 187-195, 2008
-
(2008)
Dev Dyn
, vol.237
, pp. 187-195
-
-
Cann, G.M.1
Guignabert, C.2
Ying, L.3
Deshpande, N.4
Bekker, J.M.5
Wang, L.6
Zhou, B.7
Rabinovitch, M.8
-
61
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B: Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402: 672-676, 1999
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
62
-
-
41149128707
-
Protective effects of low-dose carbon monoxide against renal fibrosis induced by unilateral ureteral obstruction
-
Wang L, Lee JY, Kwak JH, He Y, Kim SI, Choi ME: Protective effects of low-dose carbon monoxide against renal fibrosis induced by unilateral ureteral obstruction. Am J Physiol Renal Physiol 294: 508-517, 2008
-
(2008)
Am J Physiol Renal Physiol
, vol.294
, pp. 508-517
-
-
Wang, L.1
Lee, J.Y.2
Kwak, J.H.3
He, Y.4
Kim, S.I.5
Choi, M.E.6
-
63
-
-
0024405810
-
Environment-dependent growth inhibition of human epidermal keratinocytes by recombinant human transforming growth factor-beta
-
Rollins BJ, O'Connell TM, Bennett G, Burton LE, Stiles CD, Rheinwald JG: Environment-dependent growth inhibition of human epidermal keratinocytes by recombinant human transforming growth factor-beta. J Cell Physiol 139: 455-462, 1989
-
(1989)
J Cell Physiol
, vol.139
, pp. 455-462
-
-
Rollins, B.J.1
O'Connell, T.M.2
Bennett, G.3
Burton, L.E.4
Stiles, C.D.5
Rheinwald, J.G.6
-
64
-
-
78549252103
-
TGF-beta1 protects against mesangial cell apoptosis via induction of autophagy
-
Ding Y, Kim JK, Kim SI, Na HJ, Jun SY, Lee SJ, Choi ME: TGF-beta1 protects against mesangial cell apoptosis via induction of autophagy. J Biol Chem 285: 37909-37919, 2010
-
(2010)
J Biol Chem
, vol.285
, pp. 37909-37919
-
-
Ding, Y.1
Kim, J.K.2
Kim, S.I.3
Na, H.J.4
Jun, S.Y.5
Lee, S.J.6
Choi, M.E.7
|