Silicon dioxide nanoparticles increase macrophage atherogenicity: Stimulation of cellular cytotoxicity, oxidative stress, and triglycerides accumulation

Environmental Toxicology

Volumn 31, Issue 6, 2016, Pages 713-723

  Petrick, Lauren ^a   Rosenblat, Mira ^a   Paland, Nicole ^a   Aviram, Michael ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

ATGL; Cholesterol; Macrophages; Reactive oxygen species; Silicon dioxide nanoparticles; Triglycerides

Indexed keywords

BIOCHEMISTRY; CELL CULTURE; CELLS; CELLULAR MANUFACTURING; CHOLESTEROL; CYTOLOGY; CYTOTOXICITY; NANOPARTICLES; OXIDATIVE STRESS; SILICA; SILICON OXIDES; VEGETABLE OILS;

ATGL; CELLULAR CYTOTOXICITY; CHOLESTEROL METABOLISM; HORMONE-SENSITIVE LIPASE; LACTATE DEHYDROGENASE; REACTIVE OXYGEN SPECIES; SILICON DIOXIDE NANOPARTICLES; TRIGLYCERIDES;

MACROPHAGES;

ADIPOSE TRIGLYCERIDE LIPASE; CASPASE 3; CHOLESTEROL; HORMONE SENSITIVE LIPASE; LACTATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; SILICA NANOPARTICLE; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; METAL NANOPARTICLE; SILICON DIOXIDE;

CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; ESTER; HYDROLYSIS; METABOLISM; METABOLITE; NANOPARTICLE; ORGANIC COMPOUND; OXIDATION; OXYGEN; PROTEIN; SILICON; TOXICITY;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATHEROGENESIS; CELL DEATH; CELL LYSATE; CELL MEDIATED CYTOTOXICITY; CELLULAR SECRETION; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DNA DEGRADATION; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; LIPOLYSIS; MACROPHAGE; MACROPHAGE CULTURE; MITOCHONDRIAL MEMBRANE; MOUSE; NANOTOXICOLOGY; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PHOTON CORRELATION SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; ANIMAL; ATHEROSCLEROSIS; CELL LINE; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; RISK FACTOR;

MURINAE;

ANIMALS; ATHEROSCLEROSIS; CELL LINE; MACROPHAGES; METAL NANOPARTICLES; MICE; OXIDATIVE STRESS; RISK FACTORS; SILICON DIOXIDE; TRIGLYCERIDES;

EID: 84919460055     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.22084     Document Type: Article

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