Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages

Journal of Biological Chemistry

Volumn 286, Issue 9, 2011, Pages 7418-7428

  Aflaki, Elma ^a   Radović, Branislav ^a   Chandak, Prakash G ^a   Kolb, Dagmar ^a,b   Eisenberg, Tobias ^b   Ring, Julia ^b   Fertschai, Ismene ^a   Uellen, Andreas ^a   Wolinski, Heimo ^b   Kohlwein, Sepp Dieter ^b   Zechner, Rudolf ^b   Levak Frank, Sanja ^a   Sattler, Wolfgang ^a   Graier, Wolfgang F ^a   Malli, Roland ^a   Madeo, Frank ^b   Kratky, Dagmar ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADP-RIBOSE; APOPTOSIS; APOPTOSIS-INDUCING FACTORS; APOPTOTIC; APOPTOTIC RESPONSE; ATHEROSCLEROTIC LESIONS; CASPASE-3; CYTOCHROME C; CYTOSOLIC; ELEVATED LEVEL; IN-VITRO; INTRACELLULAR CHOLESTEROL; MITOCHONDRIAL APOPTOSIS; MITOCHONDRIAL DYSFUNCTION; NUCLEAR LOCALIZATION; PERITONEAL MACROPHAGE; PHOSPHATIDYLSERINE; PLASMA MEMBRANES; POLYMERASE CLEAVAGE; PROGRAMMED CELL DEATHS; PROMINENT FEATURES; REACTIVE OXYGEN SPECIES; TRIACYLGLYCEROLS; VERY LOW DENSITY LIPOPROTEINS; WILD TYPES;

CELL DEATH; CELL MEMBRANES; ENZYMES; GLYCEROL; MITOCHONDRIA; OXYGEN;

MACROPHAGES;

ADENOSINE DIPHOSPHATE RIBOSE; APOPTOSIS INDUCING FACTOR; CALCIUM ION; CASPASE 3; CASPASE 7; CYTOCHROME C; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL MEMBRANE; CELL NUCLEUS; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME RELEASE; FEMALE; IN VITRO STUDY; LIPID HYDROLYSIS; LIPOLYSIS; MITOCHONDRION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; TISSUE TYPES;

ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; ATHEROSCLEROSIS; CELLS, CULTURED; CHOLESTEROL, VLDL; FEMALE; LIPASE; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MITOCHONDRIA; SIGNAL TRANSDUCTION; TRIGLYCERIDES;

MUS;

EID: 79953208051     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.175703     Document Type: Article

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