MiR-22 regulates 5-FU sensitivity by inhibiting autophagy and promoting apoptosis in colorectal cancer cells

Cancer Letters

Volumn 356, Issue 2, 2015, Pages 781-790

  Zhang, Honghe ^a,d   Tang, Jinlong ^a,b   Li, Chen ^a,d   Kong, Jianlu ^a,d   Wang, Jingyu ^a,c   Wu, Yihua ^a   Xu, Enping ^a,d   Lai, Maode ^a,d  

^a ZHEJIANG UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Department of Stomatology The First Hospital of Jiaxing   (China)

^d Key Laboratory of Gastroenterology of Zhejiang Province   (China)

Author keywords

5 FU; Apoptosis; Autophagy; Colorectal cancer; MiR 22

Indexed keywords

FLUOROURACIL; MICRORNA 22; ANTINEOPLASTIC ANTIMETABOLITE; APOPTOSIS REGULATORY PROTEIN; MESSENGER RNA; MICRORNA; MIRN22 MICRORNA, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; BTG1 GENE; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SENSITIVITY; GENE; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; POSTTRANSCRIPTIONAL GENE SILENCING; TREATMENT OUTCOME; TUMOR XENOGRAFT; ADENOCARCINOMA; ANIMAL; BAGG ALBINO MOUSE; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DRUG EFFECTS; DRUG RESISTANCE; DRUG SCREENING; ENZYME IMMUNOASSAY; GENE EXPRESSION REGULATION; GENETICS; NUDE MOUSE; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

ADENOCARCINOMA; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BLOTTING, WESTERN; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DRUG RESISTANCE, NEOPLASM; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84919432647     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.10.029     Document Type: Article

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