Inhibition of PGC-1α after chemotherapy-mediated insult confines multiple myeloma cell survival by affecting ROS accumulation

Oncology Reports

Volumn 33, Issue 2, 2015, Pages 899-904

  Cao, Dedong ^a,b   Jin, Lu ^a   Zhou, Hao ^a,c   Yu, Wen ^a,c   Hu, Yu ^a,c   Guo, Tao ^a,c  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Bortezomib; Chemotherapy; Multiple myeloma; PGC 1 ; Reactive oxygen species

Indexed keywords

BORTEZOMIB; CATALASE; DEXAMETHASONE; MANGANESE SUPEROXIDE DISMUTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REACTIVE OXYGEN METABOLITE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; BORONIC ACID DERIVATIVE; PPARGC1A PROTEIN, HUMAN; PYRAZINE DERIVATIVE; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; FLOW CYTOMETRY; IN VITRO STUDY; MTT ASSAY; MULTIPLE MYELOMA; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; BORONIC ACIDS; CATALASE; CELL LINE, TUMOR; CELL SURVIVAL; DEXAMETHASONE; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MITOCHONDRIA; MULTIPLE MYELOMA; OXIDATIVE STRESS; PYRAZINES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTORS;

EID: 84919429788     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3635     Document Type: Article

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