Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells

Redox Biology

Volumn 4, Issue , 2015, Pages 14-22

  Barlow, Jonathan ^a   Hirschberg Jensen, Verena ^a   Affourtit, Charles ^a  

^a UNIVERSITY OF PLYMOUTH   (United Kingdom)

Author keywords

Cytoprotection; Glucolipotoxicity; INS 1E insulinoma cells; Mitochondrial dysfunction; Non esterified fatty acids; Obesity; Pancreatic beta cells; Reactive oxygen species; Type 2 diabetes; Uncoupling protein 2 (UCP2)

Indexed keywords

ANTIMYCIN A1; GLUCOSE; MITOCHONDRIAL REACTIVE OXYGEN METABOLITE; PALMITIC ACID; PALMITOLEIC ACID; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2; INSULIN; ION CHANNEL; MITOCHONDRIAL PROTEIN; MONOUNSATURATED FATTY ACID; UCP2 PROTEIN, HUMAN;

ARTICLE; CELL COUNT; CELL CULTURE; CELL LOSS; CELL VIABILITY; CYTOTOXICITY; INSULINOMA; NONHUMAN; OXIDATION; PANCREAS ISLET BETA CELL; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PANCREATIC NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

ANTIMYCIN A; CELL COUNT; CELL LINE, TUMOR; FATTY ACIDS, MONOUNSATURATED; GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INSULINOMA; ION CHANNELS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATION-REDUCTION; PANCREATIC NEOPLASMS; REACTIVE OXYGEN SPECIES; UNCOUPLING PROTEIN 2;

EID: 84919395041     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2014.11.009     Document Type: Article

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