PI3K/Akt/uncoupling protein 2 signaling pathway may be involved in cell senescence and apoptosis induced by angiotensin II in human vascular endothelial cells

Molecular Biology Reports

Volumn 41, Issue 10, 2014, Pages 6931-6937

  Li, Ping ^a   Guo, Xin ^a,b   Lei, Pingping ^a   Shi, Shoujun ^a   Luo, Shike ^a   Cheng, Xiaoshu ^a  

^a NANCHANG UNIVERSITY   (China)

^b First Affiliated Hospital of Gannan Medical University   (China)

Author keywords

Angiotensin II; Cell apoptosis; Cell senescence; Oxidative stress; PI3K Akt signaling pathway; Uncoupling protein 2

Indexed keywords

ANGIOTENSIN II; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; TELOMERASE REVERSE TRANSCRIPTASE; UNCOUPLING PROTEIN 2; ION CHANNEL; MATRIX METALLOPROTEINASE; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; REACTIVE OXYGEN METABOLITE; TELOMERASE;

APOPTOSIS; ARTICLE; CELL AGING; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PROTEIN FUNCTION; SENESCENCE; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; CELL LINE; DRUG EFFECTS; ENDOTHELIUM CELL; METABOLISM;

ANGIOTENSIN II; APOPTOSIS; CELL AGING; CELL LINE; ENDOTHELIAL CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; ION CHANNELS; MATRIX METALLOPROTEINASES; MITOCHONDRIAL PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MYC; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TELOMERASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84919348844     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-014-3580-0     Document Type: Article

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