-
1
-
-
0033764673
-
Advances in interleukin 2 receptor targeted treatment
-
Morris JC, Waldmann TA. Advances in interleukin 2 receptor targeted treatment. Ann Rheum Dis. 2000;59(suppl 1):i109-i114.
-
(2000)
Ann Rheum Dis
, vol.59
, Issue.SUPPL. 1
-
-
Morris, J.C.1
Waldmann, T.A.2
-
2
-
-
33750219508
-
Both integrated and differential regulation of components of the IL-2/IL-2 receptor system
-
Kim HP, Imbert J, Leonard WJ. Both integrated and differential regulation of components of the IL-2/IL-2 receptor system. Cytokine Growth Factor Rev. 2006;17:349-366.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 349-366
-
-
Kim, H.P.1
Imbert, J.2
Leonard, W.J.3
-
3
-
-
0019254359
-
Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma
-
Poiesz BJ, Ruscetti FW, Gazdar AF, Bunn PA, Minna JD, Gallo RC. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci U S A. 1980;77: 7415-7419.
-
(1980)
Proc Natl Acad Sci U S A
, vol.77
, pp. 7415-7419
-
-
Poiesz, B.J.1
Ruscetti, F.W.2
Gazdar, A.F.3
Bunn, P.A.4
Minna, J.D.5
Gallo, R.C.6
-
4
-
-
13144276369
-
Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins
-
Takemoto S, Mulloy JC, Cereseto A, et al. Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins. Proc Natl Acad Sci U S A. 1997; 94:13897-13902.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13897-13902
-
-
Takemoto, S.1
Mulloy, J.C.2
Cereseto, A.3
-
5
-
-
0029005549
-
Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I
-
Migone TS, Lin JX, Cereseto A, et al. Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I. Science. 1995;269:79-81.
-
(1995)
Science
, vol.269
, pp. 79-81
-
-
Migone, T.S.1
Lin, J.X.2
Cereseto, A.3
-
6
-
-
0029128045
-
Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells
-
Xu X, Kang S, Heidenreich O, Okerholm M, O'Shea JJ, Nerenberg Ml. Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells. J Clin Invest. 1995;96: 1548-1555.
-
(1995)
J Clin Invest
, vol.96
, pp. 1548-1555
-
-
Xu, X.1
Kang, S.2
Heidenreich, O.3
Okerholm, M.4
O'Shea, J.J.5
Nerenberg, M.6
-
7
-
-
0034327770
-
Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1 -transformed human T cells
-
Kirken RA, Erwin RA, Wang L Wang Y, Rui H, Farrar WL. Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1 -transformed human T cells. J Immunol. 2000;165:5097-5104.
-
(2000)
J Immunol
, vol.165
, pp. 5097-5104
-
-
Kirken, R.A.1
Erwin, R.A.2
Wang, L.3
Wang, Y.4
Rui, H.5
Farrar, W.L.6
-
8
-
-
0034235836
-
Bcl-X(L) is up-regulated by HTLV-I and HTLV-II in vitro and in ex vivo ATLL samples
-
Nicot C, Mahieux R, Takemoto S, Franchini G. Bcl-X(L) is up-regulated by HTLV-I and HTLV-II in vitro and in ex vivo ATLL samples. Blood. 2000; 96:275-281.
-
(2000)
Blood
, vol.96
, pp. 275-281
-
-
Nicot, C.1
Mahieux, R.2
Takemoto, S.3
Franchini, G.4
-
9
-
-
33746589840
-
Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence
-
DattaA, Bellon M, Sinha-Datta U, et al. Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence. Blood. 2006;108:1021-1029.
-
(2006)
Blood
, vol.108
, pp. 1021-1029
-
-
Datta, A.1
Bellon, M.2
Sinha-Datta, U.3
-
10
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn EH. Switching and signaling at the telomere. Cell. 2001;106:661-673.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
11
-
-
0030067487
-
Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues
-
Avilion AA, Piatyszek MA, Gupta J, Shay JW, Bacchetti S. Greider CW. Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. Cancer Res. 1996;56:645-650.
-
(1996)
Cancer Res
, vol.56
, pp. 645-650
-
-
Avilion, A.A.1
Piatyszek, M.A.2
Gupta, J.3
Shay, J.W.4
Bacchetti, S.5
Greider, C.W.6
-
12
-
-
0032485416
-
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2). the catalytic subunit of telomerase
-
Counter CM, Meyerson M, Eaton EN, et al. Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2). the catalytic subunit of telomerase. Oncogene. 1998;16: 1217-1222.
-
(1998)
Oncogene
, vol.16
, pp. 1217-1222
-
-
Counter, C.M.1
Meyerson, M.2
Eaton, E.N.3
-
13
-
-
4944240745
-
Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-l-transformed cells
-
Sinha-DattaU, Horikawa I, Michishita E, et al. Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-l-transformed cells. Blood. 2004;104:2523-2531.
-
(2004)
Blood
, vol.104
, pp. 2523-2531
-
-
DattaU, S.1
Horikawa, I.2
Michishita, E.3
-
14
-
-
33748871127
-
Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia
-
Bellon M, Datta A, Brown M, et al. Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia. Int J Cancer. 2006;119:2090-2097.
-
(2006)
Int J Cancer
, vol.119
, pp. 2090-2097
-
-
Bellon, M.1
Datta, A.2
Brown, M.3
-
15
-
-
0034690244
-
HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300
-
Nicot C, Mahieux R, Opavsky R, et al. HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300. Oncogene. 2000;19:2155-64.
-
(2000)
Oncogene
, vol.19
, pp. 2155-2164
-
-
Nicot, C.1
Mahieux, R.2
Opavsky, R.3
-
16
-
-
32644476664
-
Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest
-
Bae-Jump VL, Zhou C, Gehrig PA, Whang YE, Boggess JF. Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest. Gynecol Oncol. 2006:100:487-94.
-
(2006)
Gynecol Oncol
, vol.100
, pp. 487-494
-
-
Bae-Jump, V.L.1
Zhou, C.2
Gehrig, P.A.3
Whang, Y.E.4
Boggess, J.F.5
-
17
-
-
0029941308
-
Cell cycledependent modulation of telomerase activity in tumor cells
-
Zhu X, Kumar R, Mandal M, et al. Cell cycledependent modulation of telomerase activity in tumor cells. Proc Natl Acad Sci U S A. 1996;93: 6091-6095.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 6091-6095
-
-
Zhu, X.1
Kumar, R.2
Mandal, M.3
-
18
-
-
31944444988
-
Cell cycle-regulated trafficking of human telomerase to telomeres
-
Tomlinson RL, Ziegler TD, Supakomdej T Terns RM, Terns MP. Cell cycle-regulated trafficking of human telomerase to telomeres. Mol Biol Cell. 2006;17:955-965.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 955-965
-
-
Tomlinson, R.L.1
Ziegler, T.D.2
Supakomdej, T.3
Terns, R.M.4
Terns, M.P.5
-
19
-
-
0027939430
-
Role of phosphatidylinositol-3-kinase in insulin receptor signaling: Studies with inhibitor, LY294002
-
Sanchez-Margalet V, Goldfine ID, Vlahos CJ, Sung CK. Role of phosphatidylinositol-3-kinase in insulin receptor signaling: studies with inhibitor, LY294002. Biochem Biophys Res Commun. 1994;204:446-452.
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 446-452
-
-
Sanchez-Margalet, V.1
Goldfine, I.D.2
Vlahos, C.J.3
Sung, C.K.4
-
20
-
-
27244438058
-
Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL)
-
Fukuda R, Hayashi A, UtsunomiyaA, et al. Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL). Proc Natl Acad Sci U S A. 2005;102:15213-15218.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15213-15218
-
-
Fukuda, R.1
Hayashi, A.2
UtsunomiyaA3
-
21
-
-
27144477415
-
Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells
-
Jeong SJ, Pise-Masison CA, Radonovich MF, Park HU, Brady JN. Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells. Oncogene. 2005;24: 6719-6728.
-
(2005)
Oncogene
, vol.24
, pp. 6719-6728
-
-
Jeong, S.J.1
Pise-Masison, C.A.2
Radonovich, M.F.3
Park, H.U.4
Brady, J.N.5
-
22
-
-
0033532056
-
Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit
-
Kang SS, Kwon T, Kwon DY, Do SI. Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit. J Biol Chem. 1999;274: 13085-13090.
-
(1999)
J Biol Chem
, vol.274
, pp. 13085-13090
-
-
Kang, S.S.1
Kwon, T.2
Kwon, D.Y.3
Do, S.I.4
-
23
-
-
34147124095
-
Longitudinal inhibition of PI3K/Akt/m TOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells
-
Ikezoe T Nishioka C, Bandobashi K, et al. Longitudinal inhibition of PI3K/Akt/m TOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells. Leuk Res. 2007;31: 673-682.
-
(2007)
Leuk Res
, vol.31
, pp. 673-682
-
-
Ikezoe, T.1
Nishioka, C.2
Bandobashi, K.3
-
24
-
-
33745621927
-
Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells
-
Tomita M, Kawakami H, Uchihara JN, et al. Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells. Retrovirology. 2006;3:22.
-
(2006)
Retrovirology
, vol.3
, pp. 22
-
-
Tomita, M.1
Kawakami, H.2
Uchihara, J.N.3
-
25
-
-
0034327770
-
Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells
-
Kirken RA, Erwin RA, Wang L, Wang Y, Rui H, Farrar WL. Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells. J Immunol. 2000;165:5097-5104.
-
(2000)
J Immunol
, vol.165
, pp. 5097-5104
-
-
Kirken, R.A.1
Erwin, R.A.2
Wang, L.3
Wang, Y.4
Rui, H.5
Farrar, W.L.6
-
27
-
-
0037207872
-
Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein
-
Akiyama M, Hideshima T, Hayashi T, et al. Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein. Cancer Res. 2003;63:18-21.
-
(2003)
Cancer Res
, vol.63
, pp. 18-21
-
-
Akiyama, M.1
Hideshima, T.2
Hayashi, T.3
-
28
-
-
0034142386
-
Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT)
-
Kyo S, Takakura M. Taira T, et al. Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT). Nucleic Acids Res. 2000;28:669-677.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 669-677
-
-
Kyo, S.1
Takakura, M.2
Taira, T.3
-
29
-
-
0343673898
-
Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1
-
Gunes C, Lichsteiner S, Vasserot AP, Englert C. Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1. Cancer Res. 2000;60:2116-2121.
-
(2000)
Cancer Res
, vol.60
, pp. 2116-2121
-
-
Gunes, C.1
Lichsteiner, S.2
Vasserot, A.P.3
Englert, C.4
-
30
-
-
33645304018
-
hTERT phosphorylation by PKC is essential for telomerase holoprotein integrity and enzyme activity in head neck cancer cells
-
Chang JT, Lu YC, Chen YJ, et al. hTERT phosphorylation by PKC is essential for telomerase holoprotein integrity and enzyme activity in head neck cancer cells. Br J Cancer. 2006;94:870-878.
-
(2006)
Br J Cancer
, vol.94
, pp. 870-878
-
-
Chang, J.T.1
Lu, Y.C.2
Chen, Y.J.3
-
31
-
-
0033601234
-
The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene
-
Oh S, Song Y, Yim J, Kim TK. The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene. J Biol Chem. 1999;274:37473-37478.
-
(1999)
J Biol Chem
, vol.274
, pp. 37473-37478
-
-
Oh, S.1
Song, Y.2
Yim, J.3
Kim, T.K.4
-
32
-
-
0030665666
-
Inhibition of the DNA-binding and transcriptional repression activity of the Wilms' tumor gene product, WT1, by cAMP-dependent protein kinasemediated phosphorylation of Ser-365 and Ser-393 in the zinc finger domain
-
Sakamoto Y Yoshida M, Semba K, Hunter T. Inhibition of the DNA-binding and transcriptional repression activity of the Wilms' tumor gene product, WT1, by cAMP-dependent protein kinasemediated phosphorylation of Ser-365 and Ser-393 in the zinc finger domain. Oncogene. 1997;15:2001-2012.
-
(1997)
Oncogene
, vol.15
, pp. 2001-2012
-
-
Sakamoto, Y.1
Yoshida, M.2
Semba, K.3
Hunter, T.4
-
33
-
-
0029853390
-
Regulation of WT1 by phosphorylation: Inhibition of DNA binding, alteration of transcriptional activity and cellular translocation
-
Ye Y, Raychaudhuri B, GurneyA, Campbell CE, Williams BR. Regulation of WT1 by phosphorylation: inhibition of DNA binding, alteration of transcriptional activity and cellular translocation. EMBO J. 1996;15:5606-5615.
-
(1996)
EMBO J
, vol.15
, pp. 5606-5615
-
-
Ye, Y.1
Raychaudhuri, B.2
Gurney, A.3
Campbell, C.E.4
Williams, B.R.5
-
34
-
-
33947195880
-
-
Bellon M. Nicot C. Telomerase: a crucial player in HTLV-1-induced human T-cell leukemia. Cancer Genomics Proteomics. 2007;4:21-25.
-
Bellon M. Nicot C. Telomerase: a crucial player in HTLV-1-induced human T-cell leukemia. Cancer Genomics Proteomics. 2007;4:21-25.
-
-
-
-
36
-
-
0035901533
-
The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells
-
Ellisen LW, Carlesso N, Cheng T, Scadden DT Haber DA. The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells. EMBO J. 2001;20:1897-1909.
-
(2001)
EMBO J
, vol.20
, pp. 1897-1909
-
-
Ellisen, L.W.1
Carlesso, N.2
Cheng, T.3
Scadden, D.T.4
Haber, D.A.5
-
37
-
-
0035203744
-
Forced expression of the Wilms tumor 1 (WT1) gene inhibits proliferation of human hematopoietic CD34(+) progenitor cells
-
Svedberg H, Richter J, Gullberg U. Forced expression of the Wilms tumor 1 (WT1) gene inhibits proliferation of human hematopoietic CD34(+) progenitor cells. Leukemia. 2001;15:1914-1922.
-
(2001)
Leukemia
, vol.15
, pp. 1914-1922
-
-
Svedberg, H.1
Richter, J.2
Gullberg, U.3
-
38
-
-
9244237089
-
Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: Implications for the involvement of WT1 in leukemogenesis
-
Yamagami T Sugiyama H, Inoue K, et al. Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis. Blood. 1996;87:2878-2884.
-
(1996)
Blood
, vol.87
, pp. 2878-2884
-
-
Yamagami, T.1
Sugiyama, H.2
Inoue, K.3
-
39
-
-
34548775721
-
Effective treatment of leukemic cell lines with wt1 siRNA
-
Glienke W, Maute L Koehl U, Esser R, Milz E, Bergmann L. Effective treatment of leukemic cell lines with wt1 siRNA. Leukemia. 2007;21:2164-2170.
-
(2007)
Leukemia
, vol.21
, pp. 2164-2170
-
-
Glienke, W.1
Maute, L.2
Koehl, U.3
Esser, R.4
Milz, E.5
Bergmann, L.6
-
40
-
-
0008421652
-
Human T-cell leukemia virus (HTLV-I) transcripts in fresh and cultured cells of patients with adult T-cell leukemia
-
Franchini G, Wong-Staal F, Gallo RC. Human T-cell leukemia virus (HTLV-I) transcripts in fresh and cultured cells of patients with adult T-cell leukemia. Proc Natl Acad Sci U S A. 1984;81:6207-6211.
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 6207-6211
-
-
Franchini, G.1
Wong-Staal, F.2
Gallo, R.C.3
-
41
-
-
0024327304
-
Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction
-
Kinoshita T Shimoyama M, Tobinai K, et al. Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction. Proc Natl Acad Sci U S A. 1989;86:5620-5624.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 5620-5624
-
-
Kinoshita, T.1
Shimoyama, M.2
Tobinai, K.3
-
42
-
-
0021990233
-
lnterleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells
-
Uchiyama T Hori T Tsudo M, et al. lnterleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells. J Clin Invest. 1985;76:446-453.
-
(1985)
J Clin Invest
, vol.76
, pp. 446-453
-
-
Uchiyama, T.1
Hori, T.2
Tsudo, M.3
-
43
-
-
38449104105
-
Regulation of telomerase and telomeres: Human tumor viruses take control
-
Bellon M. Nicot C. Regulation of telomerase and telomeres: human tumor viruses take control. J Natl Cancer Inst. 2008;100:98-108.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 98-108
-
-
Bellon, M.1
Nicot, C.2
|