Nuclear import of htert requires a bipartite nuclear localization signal and Akt-mediated phosphorylation

Journal of Cell Science

Volumn 125, Issue 11, 2012, Pages 2684-2697

  Chung, Jeeyun ^a,b   Khadka, Prabhat ^a   Chung, In Kwon ^a  

^a Yonsei University   (South Korea)

^b YALE UNIVERSITY   (United States)

Author keywords

Akt Phosphorylation; Htert; Nuclear localization signal; Telomerase

Indexed keywords

AMINO ACID; PROTEIN KINASE B; SERINE; TELOMERASE REVERSE TRANSCRIPTASE; WORTMANNIN;

ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; ENZYME INACTIVATION; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WILD TYPE;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; CELL LINE, TRANSFORMED; CELL NUCLEUS; FIBROBLASTS; FORESKIN; HUMANS; INTRACELLULAR SPACE; MALE; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; NUCLEAR LOCALIZATION SIGNALS; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBCELLULAR FRACTIONS; TELOMERASE;

EID: 84864966476     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.099267     Document Type: Article

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