Angiotensin II induces endothelial cell senescence via the activation of mitogen-activated protein kinases

Cell Biochemistry and Function

Volumn 26, Issue 4, 2008, Pages 459-466

  Shan, Haiyan ^a   Bai, XiaoJuan ^a   Chen, XiangMei ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Angiotensin II; Endothelial cell; Mitogen activated protein kinase; Senescence

Indexed keywords

ANGIOTENSIN II; BETA GALACTOSIDASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2;

AGING; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL SHAPE; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; SIGNAL TRANSDUCTION; STAINING;

ANGIOTENSIN II; CELL AGING; CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; UMBILICAL CORD;

EID: 46749085503     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1467     Document Type: Article

References (40)

1. Folkow B, Svanborg A. Physiology of cardiovascular aging. Physiol Rev 1993; 73: 725-764.
2. Dohi Y, Kojima M, Sato K, et al. Age-related changes in vascular smooth muscle and endothelium. Drug Aging 1995; 7: 278-291.
3. Docherty JR. Cardiovascular responses in ageing: a review. Pharmacol Rev 1990; 42: 103-125.
4. Lakatta EG. Cardiovascular regulatory mechanisms in advanced age. Physiol Rev 1993; 73: 413-467.
5. Kuniya A, Kudej RK, Shen YT, et al. Peripheral vascular endothelial dysfunction and apoptosis in old monkeys. Arterioscler Thromb Vasc Biol 2000; 20: 1493-1502.
6. Shipley RD, Muller JM. Aging decreases vasoconstrictor responses of coronary resistance arterioles through endothelium-dependent mechanisms. Cardiovasc Res 2005; 66: 374-383.
7. Cooper LT, Cooke JP, Dzau VJ. The vasculopathy of aging. J Gerontol 1994; 49: B191-B196.
8. Minamino T, Miyauchi H, Yoshida T, et al. Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation 2002; 105: 1541-1544.
9. Minamino T, Yoshida T, Tatcno K, et al. Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation 2003; 108: 2264-2269.
10. Heymes C, Silverstre JS, Cortes CL, et al. Cardiac senescence is associated with enhanced expression of angiotensin II receptor subtypes. Endocrinology 1998; 139: 2579-2587.
11. Mukai Y, Shimokawa H, Higashi M, et al. Inhibitor renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats. Arterioscler Thromb Vasc Biol 2002; 22: 1445-1450.
12. Kansui Y, Fujii K, Goto K, et al. Ang II receptor antagonist improves a related endothelial dysfunction. J Hypertens 2002; 20: 439-446.
13. Chang L, Karin M. Mammalian MAP kinase signaling cascades. Nature 2001; 410: 37-40.
14. Giuseppa G, Catherine M, Giasson E, et al. Role of p44/42 MAP kinase in the age-dependent increase in vascular smooth muscle cell proliferation and neointimal formation. Arterioscler Thromb Vasc Biol 2003; 23: 204-210.
15. Bilato C, Crow MT. Atherosclerosis and the vascular biology of aging. Aging Clin Exp Res 1996; 8: 221-234.
16. Dimri GP, Lee X, Basile G, et al. A biomarker that identifies senescence human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 1995; 92: 9363-9367.
17. Griending QM, Sorescu D, Lassegue B, et al. Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol 2000; 20: 2175-2183.
18. Lorenzini A, Tresini M, Dewan MM, et al. Role of Raf/MEK/ERK and the PI3K/Akt (PKB) pathways in fibroblast senescence. Exp Gerontol 2002; 37: 1149-1156.
19. Serrano M, Blasco MA. Putting the stress on senescence. Curr Opin Cell Biol 2001; 13: 748-753.
20. Toussaint O, Medrano EE, Zglinicki T. Cellular and molecular mechanisms of stress-induced premature senescence(SIPS) of human diploid fibroblasts and melanocytes. Exp Gerontol 2000; 35: 927-945.
21. Wang XD, Chen XM, Wang JZ, et al. Signal transducers and activators of transcription 3 mediates up-regulation of angiotensin II-induced tissue inhibitor of metalloproteinase-1 expression in cultured human senescent fibroblasts. Chin Med J 2006; 119: 1094-1102.
22. Heymes C, Silverstre JS, Cortes CL, et al. Cardiac senescence is associated with enhanced expression of angiotensin II receptor subtypes. Endocrinology 1998; 139: 2579-2587.
23. Chen H, Li D, Mehta JL. Modulation of matrix metalloproteinase-1, its tissue inhibitor, and nuclear factor-kappB by losartan in hypercholesterolemic rabbits. J Cardiovasc Pharmacol 2002; 39: 2579-2587.
24. Mukai Y, Shimokawa H, Higashi M, et al. Inhibitor renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats. Arterioscler Thromb Vasc Biol 2002; 22: 1445-1450.
25. Kansui Y, Fujii K, Goto K, et al. Ang II receptor antagonist improves a related endothelial dysfunction. J Hypertens 2002; 20: 439-446.
26. Jorge D, Erusalimsky JD, Kurz DJ. Cellular senescence in vivo: its relevance in ageing and cardiovascular disease. Exp Gerontol 2005; 40: 634-642.
27. Zarubin T, Han JH. Activation and signaling of the p38 MAP kinase pathway. Cell Res 2005; 15: 11-18.
28. Yoon SO, Yun CH, Chung AS. Dose effect of oxidative stress on signal transduction in aging. Mech Aging Develop 2002; 123: 1597-1604.
29. Shintaro K, Toshio I, Katsunobu K, et al. Hyperglycemia accelerated endothelial progenitor cell senescence via the activation of p38 mitogen-activated protein kinase. Circ J 2006; 70: 1076-1082.
30. Wang W, Chen JX, Liao R, et al. Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. Mol Cell Biol 2002; 22: 3389-3403.
31. Imanishi T, Takuzo H, Nishio I. Estrogen reduces angiotensin II-induced acceleration of senescence in endothelial progenitor cells. Hypertens Res 2005; 28: 263-271.
32. Giuseppa G, Catherine M, Giasson E, et al. Role of p44/42 MAP kinase in the age-dependent increase in vascular smooth muscle cell proliferation and neointimal formation. Arterioscler Thromb Vasc Biol 2003; 23: 204-210.
33. Bilato C, Crow MT. Atherosclerosis and the vascular biology of aging. Aging Clin Exp Res 1996; 8: 221-234.
34. L in response to DNA damage. J Biol Chem 2000; 275: 322-327.
35. Schinzel A, Kaufmann T, Borner C. Bcl-2 family members: integrators of survival and death. Biochem Biophys 2004; 1644: 95-105.
36. L and E1B-19K proteins inhibit p53-induced irreversible growth arrest and senescence by preventing reactive oxygen species-dependent p38 activation. J.Biol Chem 2004; 279: 17765-17771.
37. Kumazaki T, Sasaki M, Nishiyama M, et al. Effect of Bcl-2 down-regulation on cellular life span. Biogerontology 2002; 3: 291-300.
38. Steller H. Mechanisms and genes of cellular suicide. Science 1995; 267: 1445-1449.
39. Monti D, Salvioli S, Capri M, et al. Decreased susceptibility to oxidative stress-induced apoptosis of peripheral blood mononuclear cells from healthy elderly and centenarians. Mech Aging Dev 2000; 121: 239-250.
40. Phaneuf S, Leeuwenburgh C. Cytochrome c release from mitochondria in the ageing heart: apossible mecheanism for apoptosis with age. Am J Physiol Regul Comp Physiol 2002; 282: R423-R430.